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t(1;11)(q21;q23)

MedGen UID:: 1718878
•Concept ID:: C5239094
•: Cell or Molecular Dysfunction

Definition

A cytogenetic abnormality that refers to the translocation of the long arm (q21) of chromosome 1 and the long arm (q23) of chromosome 11. It is associated with KMT2A (MLL)/MLLT11 (AF1Q) fusions, acute myeloid leukemia and some cases of acute lymphoblastic leukemia. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVt(1;11)(q21;q23)

Molecular Abnormality
- Cytogenetic Abnormality
  - Chromosome 1 Abnormality
    - t(1;11)(q21;q23)

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