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Metastatic Primary Peritoneal Serous Adenocarcinoma

MedGen UID:
1726246
•Concept ID:
C5418957
•
Neoplastic Process

Definition

Primary peritoneal serous adenocarcinoma that has spread from its original site of growth to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Primary Peritoneal Serous Adenocarcinoma

Professional guidelines

PubMed

Diagnosis and management of metastatic neoplasms with unknown primary.
Bochtler T, Löffler H, Krämer A
Semin Diagn Pathol 2018 May;35(3):199-206. Epub 2017 Nov 26 doi: 10.1053/j.semdp.2017.11.013. PMID: 29203116
Diagnostic and therapeutic management of cancer of an unknown primary.
Pavlidis N, Briasoulis E, Hainsworth J, Greco FA
Eur J Cancer 2003 Sep;39(14):1990-2005. doi: 10.1016/s0959-8049(03)00547-1. PMID: 12957453
Refined diagnostic criteria for implants associated with ovarian atypical proliferative serous tumors (borderline) and micropapillary serous carcinomas.
Bell KA, Smith Sehdev AE, Kurman RJ
Am J Surg Pathol 2001 Apr;25(4):419-32. doi: 10.1097/00000478-200104000-00001. PMID: 11257616

Recent clinical studies

Etiology

Genomic catastrophe, the peritoneal cavity and ovarian cancer prevention.
Yoon JY, Chapel DB, Goebel E, Qian X, Mito JK, Horowitz NS, Miron A, Soong TR, Xian W, Crum CP
J Pathol 2022 Jul;257(3):255-261. Epub 2022 Apr 18 doi: 10.1002/path.5891. PMID: 35238033
Diagnosis and management of metastatic neoplasms with unknown primary.
Bochtler T, Löffler H, Krämer A
Semin Diagn Pathol 2018 May;35(3):199-206. Epub 2017 Nov 26 doi: 10.1053/j.semdp.2017.11.013. PMID: 29203116
From the archives of the AFIP: primary peritoneal tumors: imaging features with pathologic correlation.
Levy AD, Arnáiz J, Shaw JC, Sobin LH
Radiographics 2008 Mar-Apr;28(2):583-607; quiz 621-2. doi: 10.1148/rg.282075175. PMID: 18349460
Diagnostic and therapeutic management of cancer of an unknown primary.
Pavlidis N, Briasoulis E, Hainsworth J, Greco FA
Eur J Cancer 2003 Sep;39(14):1990-2005. doi: 10.1016/s0959-8049(03)00547-1. PMID: 12957453
Role of immunohistochemistry in distinguishing epithelial peritoneal mesotheliomas from peritoneal and ovarian serous carcinomas.
Ordóñez NG
Am J Surg Pathol 1998 Oct;22(10):1203-14. doi: 10.1097/00000478-199810000-00005. PMID: 9777982

Diagnosis

Diagnosis and management of metastatic neoplasms with unknown primary.
Bochtler T, Löffler H, Krämer A
Semin Diagn Pathol 2018 May;35(3):199-206. Epub 2017 Nov 26 doi: 10.1053/j.semdp.2017.11.013. PMID: 29203116
Therapeutic strategies in epithelial ovarian cancer.
Kim A, Ueda Y, Naka T, Enomoto T
J Exp Clin Cancer Res 2012 Feb 13;31(1):14. doi: 10.1186/1756-9966-31-14. PMID: 22330607Free PMC Article
New diagnostic and molecular characteristics of malignant mesothelioma.
Davidson B
Ultrastruct Pathol 2008 Nov-Dec;32(6):227-40. doi: 10.1080/01913120802454298. PMID: 19117264
Diagnostic and therapeutic management of cancer of an unknown primary.
Pavlidis N, Briasoulis E, Hainsworth J, Greco FA
Eur J Cancer 2003 Sep;39(14):1990-2005. doi: 10.1016/s0959-8049(03)00547-1. PMID: 12957453
Primary neoplasia of the female peritoneum.
Fox H
Histopathology 1993 Aug;23(2):103-10. doi: 10.1111/j.1365-2559.1993.tb00467.x. PMID: 8406381

Therapy

Targeting progesterone signaling prevents metastatic ovarian cancer.
Kim O, Park EY, Kwon SY, Shin S, Emerson RE, Shin YH, DeMayo FJ, Lydon JP, Coffey DM, Hawkins SM, Quilliam LA, Cheon DJ, Fernández FM, Nephew KP, Karpf AR, Widschwendter M, Sood AK, Bast RC Jr, Godwin AK, Miller KD, Cho CH, Kim J
Proc Natl Acad Sci U S A 2020 Dec 15;117(50):31993-32004. Epub 2020 Dec 1 doi: 10.1073/pnas.2013595117. PMID: 33262282Free PMC Article
In vivo modeling of metastatic human high-grade serous ovarian cancer in mice.
Kim O, Park EY, Klinkebiel DL, Pack SD, Shin YH, Abdullaev Z, Emerson RE, Coffey DM, Kwon SY, Creighton CJ, Kwon S, Chang EC, Chiang T, Yatsenko AN, Chien J, Cheon DJ, Yang-Hartwich Y, Nakshatri H, Nephew KP, Behringer RR, Fernández FM, Cho CH, Vanderhyden B, Drapkin R, Bast RC Jr, Miller KD, Karpf AR, Kim J
PLoS Genet 2020 Jun;16(6):e1008808. Epub 2020 Jun 4 doi: 10.1371/journal.pgen.1008808. PMID: 32497036Free PMC Article
Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma.
De Thaye E, Van de Vijver K, Van der Meulen J, Taminau J, Wagemans G, Denys H, Van Dorpe J, Berx G, Ceelen W, Van Bocxlaer J, De Wever O
Sci Rep 2020 Apr 21;10(1):6688. doi: 10.1038/s41598-020-63738-6. PMID: 32317693Free PMC Article
Therapeutic strategies in epithelial ovarian cancer.
Kim A, Ueda Y, Naka T, Enomoto T
J Exp Clin Cancer Res 2012 Feb 13;31(1):14. doi: 10.1186/1756-9966-31-14. PMID: 22330607Free PMC Article
Primary peritoneal papillary serous adenocarcinoma: clinical and management aspects.
Altaras MM, Aviram R, Cohen I, Cordoba M, Weiss E, Beyth Y
Gynecol Oncol 1991 Mar;40(3):230-6. doi: 10.1016/0090-8258(90)90283-q. PMID: 2013445

Prognosis

Biomarkers expression among paired serous ovarian cancer primary lesions and their peritoneal cavity metastases in treatment-naïve patients: A single-center study.
Nikas IP, Lee C, Song MJ, Kim B, Ryu HS
Cancer Med 2022 Jun;11(11):2193-2203. Epub 2022 Feb 25 doi: 10.1002/cam4.4600. PMID: 35212471Free PMC Article
Diagnosis and management of metastatic neoplasms with unknown primary.
Bochtler T, Löffler H, Krämer A
Semin Diagn Pathol 2018 May;35(3):199-206. Epub 2017 Nov 26 doi: 10.1053/j.semdp.2017.11.013. PMID: 29203116
Therapeutic strategies in epithelial ovarian cancer.
Kim A, Ueda Y, Naka T, Enomoto T
J Exp Clin Cancer Res 2012 Feb 13;31(1):14. doi: 10.1186/1756-9966-31-14. PMID: 22330607Free PMC Article
Diagnostic and therapeutic management of cancer of an unknown primary.
Pavlidis N, Briasoulis E, Hainsworth J, Greco FA
Eur J Cancer 2003 Sep;39(14):1990-2005. doi: 10.1016/s0959-8049(03)00547-1. PMID: 12957453
Primary peritoneal papillary serous adenocarcinoma: clinical and management aspects.
Altaras MM, Aviram R, Cohen I, Cordoba M, Weiss E, Beyth Y
Gynecol Oncol 1991 Mar;40(3):230-6. doi: 10.1016/0090-8258(90)90283-q. PMID: 2013445

Clinical prediction guides

Genomic catastrophe, the peritoneal cavity and ovarian cancer prevention.
Yoon JY, Chapel DB, Goebel E, Qian X, Mito JK, Horowitz NS, Miron A, Soong TR, Xian W, Crum CP
J Pathol 2022 Jul;257(3):255-261. Epub 2022 Apr 18 doi: 10.1002/path.5891. PMID: 35238033
Diagnosis and management of metastatic neoplasms with unknown primary.
Bochtler T, Löffler H, Krämer A
Semin Diagn Pathol 2018 May;35(3):199-206. Epub 2017 Nov 26 doi: 10.1053/j.semdp.2017.11.013. PMID: 29203116
Metachronous serous endometrial intraepithelial carcinoma and serous peritoneal carcinoma: analysis of probable independent lesions.
Furuya M, Sato T, Tanaka R, Yamamoto M, Yokota NR, Miyagi E
Diagn Pathol 2016 Nov 14;11(1):130. doi: 10.1186/s13000-016-0585-0. PMID: 27842566Free PMC Article
ATP-based chemotherapy response assay in primary or recurrent ovarian and peritoneal cancer.
Lee M, Kim SW, Nam EJ, Cho H, Kim JH, Kim YT, Kim S
Yonsei Med J 2014 Nov;55(6):1664-71. doi: 10.3349/ymj.2014.55.6.1664. PMID: 25323906Free PMC Article
Role of immunohistochemistry in distinguishing epithelial peritoneal mesotheliomas from peritoneal and ovarian serous carcinomas.
Ordóñez NG
Am J Surg Pathol 1998 Oct;22(10):1203-14. doi: 10.1097/00000478-199810000-00005. PMID: 9777982

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