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COVID-19-Associated Acute Respiratory Distress Syndrome

MedGen UID:
1727950
•Concept ID:
C5419164
•
Disease or Syndrome
Synonym: SARS-CoV-2-Associated Acute Respiratory Distress Syndrome

Definition

Acute respiratory distress syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCOVID-19-Associated Acute Respiratory Distress Syndrome

Professional guidelines

PubMed

COVID-19-associated acute respiratory distress syndrome (CARDS): Current knowledge on pathophysiology and ICU treatment - A narrative review.
Pfortmueller CA, Spinetti T, Urman RD, Luedi MM, Schefold JC
Best Pract Res Clin Anaesthesiol 2021 Oct;35(3):351-368. Epub 2020 Dec 17 doi: 10.1016/j.bpa.2020.12.011. PMID: 34511224Free PMC Article
Severe covid-19 pneumonia: pathogenesis and clinical management.
Attaway AH, Scheraga RG, Bhimraj A, Biehl M, Hatipoğlu U
BMJ 2021 Mar 10;372:n436. doi: 10.1136/bmj.n436. PMID: 33692022
COVID-19-associated acute respiratory distress syndrome: is a different approach to management warranted?
Fan E, Beitler JR, Brochard L, Calfee CS, Ferguson ND, Slutsky AS, Brodie D
Lancet Respir Med 2020 Aug;8(8):816-821. Epub 2020 Jul 6 doi: 10.1016/S2213-2600(20)30304-0. PMID: 32645311Free PMC Article

Recent clinical studies

Etiology

Randomized Phase 3 Trial of Ruxolitinib for COVID-19-Associated Acute Respiratory Distress Syndrome.
Rein L, Calero K, Shah R, Ojielo C, Hudock KM, Lodhi S, Sadaka F, Bellam S, Palma C, Hager DN, Daniel J, Schaub R, O'Hayer K, Theodoropoulos NM
Crit Care Med 2022 Dec 1;50(12):1701-1713. Epub 2022 Oct 13 doi: 10.1097/CCM.0000000000005682. PMID: 36226977Free PMC Article
Human placenta-derived amniotic epithelial cells as a new therapeutic hope for COVID-19-associated acute respiratory distress syndrome (ARDS) and systemic inflammation.
Babajani A, Moeinabadi-Bidgoli K, Niknejad F, Rismanchi H, Shafiee S, Shariatzadeh S, Jamshidi E, Farjoo MH, Niknejad H
Stem Cell Res Ther 2022 Mar 25;13(1):126. doi: 10.1186/s13287-022-02794-3. PMID: 35337387Free PMC Article
COVID-19-Associated acute respiratory distress syndrome (CARDS): Mechanistic insights on therapeutic intervention and emerging trends.
Thapa K, Verma N, Singh TG, Kaur Grewal A, Kanojia N, Rani L
Int Immunopharmacol 2021 Dec;101(Pt A):108328. Epub 2021 Nov 3 doi: 10.1016/j.intimp.2021.108328. PMID: 34768236Free PMC Article
Consensus for the management of analgesia, sedation and delirium in adults with COVID-19-associated acute respiratory distress syndrome.
Donato M, Carini FC, Meschini MJ, Saubidet IL, Goldberg A, Sarubio MG, Olmos D, Reina R
Rev Bras Ter Intensiva 2021 Jan-Mar;33(1):48-67. doi: 10.5935/0103-507X.20210005. PMID: 33886853Free PMC Article
Severe covid-19 pneumonia: pathogenesis and clinical management.
Attaway AH, Scheraga RG, Bhimraj A, Biehl M, Hatipoğlu U
BMJ 2021 Mar 10;372:n436. doi: 10.1136/bmj.n436. PMID: 33692022

Diagnosis

Development and early diagnosis of critical illness myopathy in COVID-19 associated acute respiratory distress syndrome.
Rodriguez B, Branca M, Gutt-Will M, Roth M, Söll N, Nansoz S, Cameron DR, Tankisi H, Tan SV, Bostock H, Raabe A, Schefold JC, Jakob SM, Z'Graggen WJ
J Cachexia Sarcopenia Muscle 2022 Jun;13(3):1883-1895. Epub 2022 Apr 5 doi: 10.1002/jcsm.12989. PMID: 35384375Free PMC Article
COVID-19-associated acute respiratory distress syndrome (CARDS): Current knowledge on pathophysiology and ICU treatment - A narrative review.
Pfortmueller CA, Spinetti T, Urman RD, Luedi MM, Schefold JC
Best Pract Res Clin Anaesthesiol 2021 Oct;35(3):351-368. Epub 2020 Dec 17 doi: 10.1016/j.bpa.2020.12.011. PMID: 34511224Free PMC Article
Long-term impact of COVID-19 associated acute respiratory distress syndrome.
Aranda J, Oriol I, Martín M, Feria L, Vázquez N, Rhyman N, Vall-Llosera E, Pallarés N, Coloma A, Pestaña M, Loureiro J, Güell E, Borjabad B, León E, Franz E, Domènech A, Pintado S, Contra A, Cortés MDS, Chivite I, Clivillé R, Vacas M, Ceresuela LM, Carratalà J
J Infect 2021 Nov;83(5):581-588. Epub 2021 Aug 13 doi: 10.1016/j.jinf.2021.08.018. PMID: 34400219Free PMC Article
Consensus for the management of analgesia, sedation and delirium in adults with COVID-19-associated acute respiratory distress syndrome.
Donato M, Carini FC, Meschini MJ, Saubidet IL, Goldberg A, Sarubio MG, Olmos D, Reina R
Rev Bras Ter Intensiva 2021 Jan-Mar;33(1):48-67. doi: 10.5935/0103-507X.20210005. PMID: 33886853Free PMC Article
Severe covid-19 pneumonia: pathogenesis and clinical management.
Attaway AH, Scheraga RG, Bhimraj A, Biehl M, Hatipoğlu U
BMJ 2021 Mar 10;372:n436. doi: 10.1136/bmj.n436. PMID: 33692022

Therapy

Randomized Phase 3 Trial of Ruxolitinib for COVID-19-Associated Acute Respiratory Distress Syndrome.
Rein L, Calero K, Shah R, Ojielo C, Hudock KM, Lodhi S, Sadaka F, Bellam S, Palma C, Hager DN, Daniel J, Schaub R, O'Hayer K, Theodoropoulos NM
Crit Care Med 2022 Dec 1;50(12):1701-1713. Epub 2022 Oct 13 doi: 10.1097/CCM.0000000000005682. PMID: 36226977Free PMC Article
Pathomechanisms Underlying Hypoxemia in Two COVID-19-Associated Acute Respiratory Distress Syndrome Phenotypes: Insights From Thrombosis and Hemostasis.
Gando S, Wada T
Shock 2022 Jan 1;57(1):1-6. doi: 10.1097/SHK.0000000000001825. PMID: 34172612Free PMC Article
COVID-19-associated acute respiratory distress syndrome (CARDS): Current knowledge on pathophysiology and ICU treatment - A narrative review.
Pfortmueller CA, Spinetti T, Urman RD, Luedi MM, Schefold JC
Best Pract Res Clin Anaesthesiol 2021 Oct;35(3):351-368. Epub 2020 Dec 17 doi: 10.1016/j.bpa.2020.12.011. PMID: 34511224Free PMC Article
Consensus for the management of analgesia, sedation and delirium in adults with COVID-19-associated acute respiratory distress syndrome.
Donato M, Carini FC, Meschini MJ, Saubidet IL, Goldberg A, Sarubio MG, Olmos D, Reina R
Rev Bras Ter Intensiva 2021 Jan-Mar;33(1):48-67. doi: 10.5935/0103-507X.20210005. PMID: 33886853Free PMC Article
COVID-19 and MS disease-modifying therapies.
Berger JR, Brandstadter R, Bar-Or A
Neurol Neuroimmunol Neuroinflamm 2020 Jul;7(4) Epub 2020 May 15 doi: 10.1212/NXI.0000000000000761. PMID: 32414755Free PMC Article

Prognosis

Extracorporeal membrane oxygenation for COVID-19-associated acute respiratory distress syndrome: A nationwide analysis.
Watanabe A, Malik A, Aikawa T, Briasoulis A, Kuno T
J Med Virol 2023 Jul;95(7):e28961. doi: 10.1002/jmv.28961. PMID: 37477642
Prognostic factors associated with mortality among patients receiving venovenous extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis.
Tran A, Fernando SM, Rochwerg B, Barbaro RP, Hodgson CL, Munshi L, MacLaren G, Ramanathan K, Hough CL, Brochard LJ, Rowan KM, Ferguson ND, Combes A, Slutsky AS, Fan E, Brodie D
Lancet Respir Med 2023 Mar;11(3):235-244. Epub 2022 Oct 10 doi: 10.1016/S2213-2600(22)00296-X. PMID: 36228638Free PMC Article
Development and early diagnosis of critical illness myopathy in COVID-19 associated acute respiratory distress syndrome.
Rodriguez B, Branca M, Gutt-Will M, Roth M, Söll N, Nansoz S, Cameron DR, Tankisi H, Tan SV, Bostock H, Raabe A, Schefold JC, Jakob SM, Z'Graggen WJ
J Cachexia Sarcopenia Muscle 2022 Jun;13(3):1883-1895. Epub 2022 Apr 5 doi: 10.1002/jcsm.12989. PMID: 35384375Free PMC Article
Pathomechanisms Underlying Hypoxemia in Two COVID-19-Associated Acute Respiratory Distress Syndrome Phenotypes: Insights From Thrombosis and Hemostasis.
Gando S, Wada T
Shock 2022 Jan 1;57(1):1-6. doi: 10.1097/SHK.0000000000001825. PMID: 34172612Free PMC Article
Long-term impact of COVID-19 associated acute respiratory distress syndrome.
Aranda J, Oriol I, Martín M, Feria L, Vázquez N, Rhyman N, Vall-Llosera E, Pallarés N, Coloma A, Pestaña M, Loureiro J, Güell E, Borjabad B, León E, Franz E, Domènech A, Pintado S, Contra A, Cortés MDS, Chivite I, Clivillé R, Vacas M, Ceresuela LM, Carratalà J
J Infect 2021 Nov;83(5):581-588. Epub 2021 Aug 13 doi: 10.1016/j.jinf.2021.08.018. PMID: 34400219Free PMC Article

Clinical prediction guides

Lung transplantation for coronavirus disease 2019 associated severe acute respiratory distress syndrome.
Garza-Castillon R, Bharat A
Curr Opin Anaesthesiol 2023 Feb 1;36(1):11-19. Epub 2022 Oct 27 doi: 10.1097/ACO.0000000000001203. PMID: 36302203
Prognostic factors associated with mortality among patients receiving venovenous extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis.
Tran A, Fernando SM, Rochwerg B, Barbaro RP, Hodgson CL, Munshi L, MacLaren G, Ramanathan K, Hough CL, Brochard LJ, Rowan KM, Ferguson ND, Combes A, Slutsky AS, Fan E, Brodie D
Lancet Respir Med 2023 Mar;11(3):235-244. Epub 2022 Oct 10 doi: 10.1016/S2213-2600(22)00296-X. PMID: 36228638Free PMC Article
Clinical outcomes and lung mechanics characteristics between COVID-19 and non-COVID-19-associated acute respiratory distress syndrome: a propensity score analysis of two major randomized trials.
Tomazini BM, Costa ELV, Besen BAMP, Zampieri FG, Carvalho CRR, Caser EB, Souza-Dantas VC, Boschi E, Fumis RRL, Alencar Filho MS, Maia IS, Oliveira Filho W, Veiga VC, Avezum A, Lopes RD, Machado FR, Berwanger O, Rosa RG, Cavalcanti AB, Azevedo LCP
Rev Bras Ter Intensiva 2022;34(3):335-341. Epub 2022 Nov 4 doi: 10.5935/0103-507X.20220040-pt. PMID: 36351065Free PMC Article
Randomized Phase 3 Trial of Ruxolitinib for COVID-19-Associated Acute Respiratory Distress Syndrome.
Rein L, Calero K, Shah R, Ojielo C, Hudock KM, Lodhi S, Sadaka F, Bellam S, Palma C, Hager DN, Daniel J, Schaub R, O'Hayer K, Theodoropoulos NM
Crit Care Med 2022 Dec 1;50(12):1701-1713. Epub 2022 Oct 13 doi: 10.1097/CCM.0000000000005682. PMID: 36226977Free PMC Article
Clinical Characteristics and Outcomes of Patients With COVID-19-Associated Acute Respiratory Distress Syndrome Who Underwent Lung Transplant.
Kurihara C, Manerikar A, Querrey M, Felicelli C, Yeldandi A, Garza-Castillon R Jr, Lung K, Kim S, Ho B, Tomic R, Arunachalam A, Budinger GRS, Pesce L, Bharat A
JAMA 2022 Feb 15;327(7):652-661. doi: 10.1001/jama.2022.0204. PMID: 35085383Free PMC Article

Recent systematic reviews

Prognostic factors associated with mortality among patients receiving venovenous extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis.
Tran A, Fernando SM, Rochwerg B, Barbaro RP, Hodgson CL, Munshi L, MacLaren G, Ramanathan K, Hough CL, Brochard LJ, Rowan KM, Ferguson ND, Combes A, Slutsky AS, Fan E, Brodie D
Lancet Respir Med 2023 Mar;11(3):235-244. Epub 2022 Oct 10 doi: 10.1016/S2213-2600(22)00296-X. PMID: 36228638Free PMC Article
COVID-19-Associated acute respiratory distress syndrome (CARDS): Mechanistic insights on therapeutic intervention and emerging trends.
Thapa K, Verma N, Singh TG, Kaur Grewal A, Kanojia N, Rani L
Int Immunopharmacol 2021 Dec;101(Pt A):108328. Epub 2021 Nov 3 doi: 10.1016/j.intimp.2021.108328. PMID: 34768236Free PMC Article

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