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Reactive Hyperplasia of the Retinal Pigment Epithelium

MedGen UID:
1729204
•Concept ID:
C5420845
•
Disease or Syndrome

Definition

A reactive, non-neoplastic hyperplasia of the retinal pigment epithelium. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVReactive Hyperplasia of the Retinal Pigment Epithelium

Recent clinical studies

Etiology

Focal retinal pigment epithelial dysplasia associated with fundus flavimaculatus.
Gass JD, Hummer J
Retina 1999;19(4):297-301. doi: 10.1097/00006982-199907000-00005. PMID: 10458294

Diagnosis

Reactive Retinal Pigment Epithelium Hyperplasia in Presumed Ocular Histoplasmosis Syndrome.
Azarcon CP, Craven CM, Wells JR
Ophthalmol Retina 2022 Jan;6(1):36. doi: 10.1016/j.oret.2021.10.002. PMID: 34996538
Indolent nonprogressive multifocal choroidal lesions.
Shelsta HN, Jampol LM, Weinberg DV
Retina 2012 Feb;32(2):289-92. doi: 10.1097/IAE.0b013e318219e6e3. PMID: 21900853
Focal retinal pigment epithelial dysplasia associated with fundus flavimaculatus.
Gass JD, Hummer J
Retina 1999;19(4):297-301. doi: 10.1097/00006982-199907000-00005. PMID: 10458294
Idiopathic reactive hyperplasia of the retinal pigment epithelium.
Olsen TW, Frayer WC, Myers FL, Davis MD, Albert DM
Arch Ophthalmol 1999 Jan;117(1):50-4. doi: 10.1001/archopht.117.1.50. PMID: 9930160
Reactivity of the retinal pigment epithelium: an experimental and histopathologic study.
Frayer WC
Trans Am Ophthalmol Soc 1966;64:586-643. PMID: 5965122Free PMC Article

Therapy

Retinal pigment epithelial tear after treatment of metastatic carcinoma of the choroid.
Mames RN, Margo CE
Retina 1991;11(4):430-2. doi: 10.1097/00006982-199111040-00012. PMID: 1813962

Prognosis

Indolent nonprogressive multifocal choroidal lesions.
Shelsta HN, Jampol LM, Weinberg DV
Retina 2012 Feb;32(2):289-92. doi: 10.1097/IAE.0b013e318219e6e3. PMID: 21900853
Focal retinal pigment epithelial dysplasia associated with fundus flavimaculatus.
Gass JD, Hummer J
Retina 1999;19(4):297-301. doi: 10.1097/00006982-199907000-00005. PMID: 10458294

Clinical prediction guides

Indolent nonprogressive multifocal choroidal lesions.
Shelsta HN, Jampol LM, Weinberg DV
Retina 2012 Feb;32(2):289-92. doi: 10.1097/IAE.0b013e318219e6e3. PMID: 21900853
Retinal pigment epithelial tear after treatment of metastatic carcinoma of the choroid.
Mames RN, Margo CE
Retina 1991;11(4):430-2. doi: 10.1097/00006982-199111040-00012. PMID: 1813962
Multifocal static creamy choroidal infiltrates. An early sign of lymphoid neoplasia.
Jakobiec FA, Sacks E, Kronish JW, Weiss T, Smith M
Ophthalmology 1987 Apr;94(4):397-406. doi: 10.1016/s0161-6420(87)33453-0. PMID: 3295641

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