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Locally Advanced Oropharyngeal Carcinoma

MedGen UID:
1732207
Concept ID:
C5418791
Neoplastic Process

Definition

Oropharyngeal carcinoma that has spread to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Horáková Z, Slavik M, Veselý K, Budíková M, Kostřica R, Binková H
Klin Onkol 2019 Spring;32(3):187-196. PMID: 31216850
Masterson L, Moualed D, Masood A, Dwivedi RC, Benson R, Sterling JC, Rhodes KM, Sudhoff H, Jani P, Goon P
Cochrane Database Syst Rev 2014 Feb 15;2014(2):CD010271. doi: 10.1002/14651858.CD010271.pub2. PMID: 24532092Free PMC Article
Kann BH, Buckstein M, Carpenter TJ, Bakst R, Misiukiewicz K, Genden E, Posner M, Kostakoglu L, Som P, Gupta V
Head Neck 2014 Dec;36(12):1689-94. Epub 2014 Jan 13 doi: 10.1002/hed.23512. PMID: 24123603

Recent clinical studies

Etiology

de Sousa LG, Lazar Neto F, Dal Lago EA, Sikora A, Hanna E, Moreno A, Phan J, Glisson BS, Bell D, Ferrarotto R
Oral Oncol 2023 Mar;138:106311. Epub 2023 Jan 24 doi: 10.1016/j.oraloncology.2023.106311. PMID: 36702015
Ferris RL, Flamand Y, Weinstein GS, Li S, Quon H, Mehra R, Garcia JJ, Chung CH, Gillison ML, Duvvuri U, O'Malley BW Jr, Ozer E, Thomas GR, Koch WM, Gross ND, Bell RB, Saba NF, Lango M, Méndez E, Burtness B
J Clin Oncol 2022 Jan 10;40(2):138-149. Epub 2021 Oct 26 doi: 10.1200/JCO.21.01752. PMID: 34699271Free PMC Article
Parmar A, Macluskey M, Mc Goldrick N, Conway DI, Glenny AM, Clarkson JE, Worthington HV, Chan KK
Cochrane Database Syst Rev 2021 Dec 20;12(12):CD006386. doi: 10.1002/14651858.CD006386.pub4. PMID: 34929047Free PMC Article
Economopoulou P, Kotsantis I, Psyrri A
Int J Mol Sci 2020 May 11;21(9) doi: 10.3390/ijms21093388. PMID: 32403287Free PMC Article
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243

Diagnosis

Parmar A, Macluskey M, Mc Goldrick N, Conway DI, Glenny AM, Clarkson JE, Worthington HV, Chan KK
Cochrane Database Syst Rev 2021 Dec 20;12(12):CD006386. doi: 10.1002/14651858.CD006386.pub4. PMID: 34929047Free PMC Article
Economopoulou P, Kotsantis I, Psyrri A
Int J Mol Sci 2020 May 11;21(9) doi: 10.3390/ijms21093388. PMID: 32403287Free PMC Article
Salwey L, L'Huillier V, Zaid M, Vené Y, Tavernier L, Mauvais O
Eur Ann Otorhinolaryngol Head Neck Dis 2020 Nov;137(5):377-380. Epub 2020 Apr 25 doi: 10.1016/j.anorl.2020.03.004. PMID: 32345551
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243
Cohan DM, Popat S, Kaplan SE, Rigual N, Loree T, Hicks WL Jr
Curr Opin Otolaryngol Head Neck Surg 2009 Apr;17(2):88-94. doi: 10.1097/moo.0b013e32832984c0. PMID: 19373958

Therapy

Ferris RL, Flamand Y, Weinstein GS, Li S, Quon H, Mehra R, Garcia JJ, Chung CH, Gillison ML, Duvvuri U, O'Malley BW Jr, Ozer E, Thomas GR, Koch WM, Gross ND, Bell RB, Saba NF, Lango M, Méndez E, Burtness B
J Clin Oncol 2022 Jan 10;40(2):138-149. Epub 2021 Oct 26 doi: 10.1200/JCO.21.01752. PMID: 34699271Free PMC Article
Parmar A, Macluskey M, Mc Goldrick N, Conway DI, Glenny AM, Clarkson JE, Worthington HV, Chan KK
Cochrane Database Syst Rev 2021 Dec 20;12(12):CD006386. doi: 10.1002/14651858.CD006386.pub4. PMID: 34929047Free PMC Article
Sun XS, Tao Y, Le Tourneau C, Pointreau Y, Sire C, Kaminsky MC, Coutte A, Alfonsi M, Boisselier P, Martin L, Miroir J, Ramee JF, Delord JP, Clatot F, Rolland F, Villa J, Magne N, Elicin O, Gherga E, Nguyen F, Lafond C, Bera G, Calugaru V, Geoffrois L, Chauffert B, Zubel A, Zanna C, Brienza S, Crompton P, Rouits E, Gollmer K, Szyldergemajn S, Bourhis J
Lancet Oncol 2020 Sep;21(9):1173-1187. Epub 2020 Aug 3 doi: 10.1016/S1470-2045(20)30327-2. PMID: 32758455
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243
Maggiore RJ, Curran EK, Witt ME, Haraf DJ, Vokes EE, Cohen EE
J Geriatr Oncol 2013 Oct;4(4):327-33. Epub 2013 Jun 10 doi: 10.1016/j.jgo.2013.05.003. PMID: 24472475Free PMC Article

Prognosis

de Sousa LG, Lazar Neto F, Dal Lago EA, Sikora A, Hanna E, Moreno A, Phan J, Glisson BS, Bell D, Ferrarotto R
Oral Oncol 2023 Mar;138:106311. Epub 2023 Jan 24 doi: 10.1016/j.oraloncology.2023.106311. PMID: 36702015
Sun XS, Tao Y, Le Tourneau C, Pointreau Y, Sire C, Kaminsky MC, Coutte A, Alfonsi M, Boisselier P, Martin L, Miroir J, Ramee JF, Delord JP, Clatot F, Rolland F, Villa J, Magne N, Elicin O, Gherga E, Nguyen F, Lafond C, Bera G, Calugaru V, Geoffrois L, Chauffert B, Zubel A, Zanna C, Brienza S, Crompton P, Rouits E, Gollmer K, Szyldergemajn S, Bourhis J
Lancet Oncol 2020 Sep;21(9):1173-1187. Epub 2020 Aug 3 doi: 10.1016/S1470-2045(20)30327-2. PMID: 32758455
Economopoulou P, Kotsantis I, Psyrri A
Int J Mol Sci 2020 May 11;21(9) doi: 10.3390/ijms21093388. PMID: 32403287Free PMC Article
Castelli J, Depeursinge A, Ndoh V, Prior JO, Ozsahin M, Devillers A, Bouchaab H, Chajon E, de Crevoisier R, Scher N, Jegoux F, Laguerre B, De Bari B, Bourhis J
Eur J Cancer 2017 Apr;75:222-230. Epub 2017 Feb 24 doi: 10.1016/j.ejca.2017.01.018. PMID: 28237868
Cohan DM, Popat S, Kaplan SE, Rigual N, Loree T, Hicks WL Jr
Curr Opin Otolaryngol Head Neck Surg 2009 Apr;17(2):88-94. doi: 10.1097/moo.0b013e32832984c0. PMID: 19373958

Clinical prediction guides

Haist M, Kaufmann J, Kur IM, Zimmer S, Grabbe S, Schmidberger H, Weigert A, Mayer A
Front Immunol 2023;14:1070203. Epub 2023 Apr 28 doi: 10.3389/fimmu.2023.1070203. PMID: 37187729Free PMC Article
Wong KCW, Johnson D, Hui EP, Lam RCT, Ma BBY, Chan ATC
Cancer Treat Rev 2022 Apr;105:102361. Epub 2022 Feb 16 doi: 10.1016/j.ctrv.2022.102361. PMID: 35231870
Ferris RL, Flamand Y, Weinstein GS, Li S, Quon H, Mehra R, Garcia JJ, Chung CH, Gillison ML, Duvvuri U, O'Malley BW Jr, Ozer E, Thomas GR, Koch WM, Gross ND, Bell RB, Saba NF, Lango M, Méndez E, Burtness B
J Clin Oncol 2022 Jan 10;40(2):138-149. Epub 2021 Oct 26 doi: 10.1200/JCO.21.01752. PMID: 34699271Free PMC Article
Parmar A, Macluskey M, Mc Goldrick N, Conway DI, Glenny AM, Clarkson JE, Worthington HV, Chan KK
Cochrane Database Syst Rev 2021 Dec 20;12(12):CD006386. doi: 10.1002/14651858.CD006386.pub4. PMID: 34929047Free PMC Article
Castelli J, Depeursinge A, Ndoh V, Prior JO, Ozsahin M, Devillers A, Bouchaab H, Chajon E, de Crevoisier R, Scher N, Jegoux F, Laguerre B, De Bari B, Bourhis J
Eur J Cancer 2017 Apr;75:222-230. Epub 2017 Feb 24 doi: 10.1016/j.ejca.2017.01.018. PMID: 28237868

Recent systematic reviews

Raggini E, Mattavelli D, Zigliani G, Bossi P, Piazza C
Acta Otorhinolaryngol Ital 2024 Feb;44(1):1-12. doi: 10.14639/0392-100X-N2762. PMID: 38420716Free PMC Article
Faur CI, Falamas A, Chirila M, Roman RC, Rotaru H, Moldovan MA, Albu S, Baciut M, Robu I, Hedesiu M
Int J Oral Maxillofac Surg 2022 Nov;51(11):1373-1381. Epub 2022 Mar 10 doi: 10.1016/j.ijom.2022.02.015. PMID: 35282942
Parmar A, Macluskey M, Mc Goldrick N, Conway DI, Glenny AM, Clarkson JE, Worthington HV, Chan KK
Cochrane Database Syst Rev 2021 Dec 20;12(12):CD006386. doi: 10.1002/14651858.CD006386.pub4. PMID: 34929047Free PMC Article
Alterio D, Gugliandolo SG, Augugliaro M, Marvaso G, Gandini S, Bellerba F, Russell-Edu SW, De Simone I, Cinquini M, Starzyńska A, Zaffaroni M, Bacigalupo A, Fanetti G, Durante S, Dicuonzo S, Orecchia R, Jereczek-Fossa BA
Oral Dis 2021 Oct;27(7):1644-1653. Epub 2020 Sep 22 doi: 10.1111/odi.13599. PMID: 32810381
Jayaram SC, Muzaffar SJ, Ahmed I, Dhanda J, Paleri V, Mehanna H
Head Neck 2016 Dec;38(12):1855-1861. Epub 2016 Jul 13 doi: 10.1002/hed.24531. PMID: 27405247

Supplemental Content

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