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Locally Advanced Oropharyngeal Carcinoma

MedGen UID:
1732207
Concept ID:
C5418791
Neoplastic Process

Definition

Oropharyngeal carcinoma that has spread to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Horáková Z, Slavik M, Veselý K, Budíková M, Kostřica R, Binková H
Klin Onkol 2019 Spring;32(3):187-196. PMID: 31216850
Masterson L, Moualed D, Masood A, Dwivedi RC, Benson R, Sterling JC, Rhodes KM, Sudhoff H, Jani P, Goon P
Cochrane Database Syst Rev 2014 Feb 15;2014(2):CD010271. doi: 10.1002/14651858.CD010271.pub2. PMID: 24532092Free PMC Article
Kann BH, Buckstein M, Carpenter TJ, Bakst R, Misiukiewicz K, Genden E, Posner M, Kostakoglu L, Som P, Gupta V
Head Neck 2014 Dec;36(12):1689-94. Epub 2014 Jan 13 doi: 10.1002/hed.23512. PMID: 24123603

Recent clinical studies

Etiology

Ferris RL, Flamand Y, Weinstein GS, Li S, Quon H, Mehra R, Garcia JJ, Chung CH, Gillison ML, Duvvuri U, O'Malley BW Jr, Ozer E, Thomas GR, Koch WM, Gross ND, Bell RB, Saba NF, Lango M, Méndez E, Burtness B
J Clin Oncol 2022 Jan 10;40(2):138-149. Epub 2021 Oct 26 doi: 10.1200/JCO.21.01752. PMID: 34699271Free PMC Article
Parmar A, Macluskey M, Mc Goldrick N, Conway DI, Glenny AM, Clarkson JE, Worthington HV, Chan KK
Cochrane Database Syst Rev 2021 Dec 20;12(12):CD006386. doi: 10.1002/14651858.CD006386.pub4. PMID: 34929047Free PMC Article
Magnes T, Wagner S, Kiem D, Weiss L, Rinnerthaler G, Greil R, Melchardt T
Int J Mol Sci 2021 May 7;22(9) doi: 10.3390/ijms22094981. PMID: 34067112Free PMC Article
Qureshi HA, Abouyared M, Barber B, Houlton JJ
Curr Treat Options Oncol 2019 Apr 1;20(5):36. doi: 10.1007/s11864-019-0621-x. PMID: 30931485
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243

Diagnosis

Parmar A, Macluskey M, Mc Goldrick N, Conway DI, Glenny AM, Clarkson JE, Worthington HV, Chan KK
Cochrane Database Syst Rev 2021 Dec 20;12(12):CD006386. doi: 10.1002/14651858.CD006386.pub4. PMID: 34929047Free PMC Article
Anderson CM, Lee CM, Saunders DP, Curtis A, Dunlap N, Nangia C, Lee AS, Gordon SM, Kovoor P, Arevalo-Araujo R, Bar-Ad V, Peddada A, Colvett K, Miller D, Jain AK, Wheeler J, Blakaj D, Bonomi M, Agarwala SS, Garg M, Worden F, Holmlund J, Brill JM, Downs M, Sonis ST, Katz S, Buatti JM
J Clin Oncol 2019 Dec 1;37(34):3256-3265. Epub 2019 Oct 16 doi: 10.1200/JCO.19.01507. PMID: 31618127Free PMC Article
Mehanna H, McConkey CC, Rahman JK, Wong WL, Smith AF, Nutting C, Hartley AG, Hall P, Hulme C, Patel DK, Zeidler SV, Robinson M, Sanghera B, Fresco L, Dunn JA
Health Technol Assess 2017 Apr;21(17):1-122. doi: 10.3310/hta21170. PMID: 28409743Free PMC Article
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243
Huber MA, Tantiwongkosi B
Med Clin North Am 2014 Nov;98(6):1299-321. Epub 2014 Sep 20 doi: 10.1016/j.mcna.2014.08.005. PMID: 25443678

Therapy

Ferris RL, Flamand Y, Weinstein GS, Li S, Quon H, Mehra R, Garcia JJ, Chung CH, Gillison ML, Duvvuri U, O'Malley BW Jr, Ozer E, Thomas GR, Koch WM, Gross ND, Bell RB, Saba NF, Lango M, Méndez E, Burtness B
J Clin Oncol 2022 Jan 10;40(2):138-149. Epub 2021 Oct 26 doi: 10.1200/JCO.21.01752. PMID: 34699271Free PMC Article
Parmar A, Macluskey M, Mc Goldrick N, Conway DI, Glenny AM, Clarkson JE, Worthington HV, Chan KK
Cochrane Database Syst Rev 2021 Dec 20;12(12):CD006386. doi: 10.1002/14651858.CD006386.pub4. PMID: 34929047Free PMC Article
Sun XS, Tao Y, Le Tourneau C, Pointreau Y, Sire C, Kaminsky MC, Coutte A, Alfonsi M, Boisselier P, Martin L, Miroir J, Ramee JF, Delord JP, Clatot F, Rolland F, Villa J, Magne N, Elicin O, Gherga E, Nguyen F, Lafond C, Bera G, Calugaru V, Geoffrois L, Chauffert B, Zubel A, Zanna C, Brienza S, Crompton P, Rouits E, Gollmer K, Szyldergemajn S, Bourhis J
Lancet Oncol 2020 Sep;21(9):1173-1187. Epub 2020 Aug 3 doi: 10.1016/S1470-2045(20)30327-2. PMID: 32758455
Mehanna H, McConkey CC, Rahman JK, Wong WL, Smith AF, Nutting C, Hartley AG, Hall P, Hulme C, Patel DK, Zeidler SV, Robinson M, Sanghera B, Fresco L, Dunn JA
Health Technol Assess 2017 Apr;21(17):1-122. doi: 10.3310/hta21170. PMID: 28409743Free PMC Article
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243

Prognosis

Wong KCW, Johnson D, Hui EP, Lam RCT, Ma BBY, Chan ATC
Cancer Treat Rev 2022 Apr;105:102361. Epub 2022 Feb 16 doi: 10.1016/j.ctrv.2022.102361. PMID: 35231870
Magnes T, Wagner S, Kiem D, Weiss L, Rinnerthaler G, Greil R, Melchardt T
Int J Mol Sci 2021 May 7;22(9) doi: 10.3390/ijms22094981. PMID: 34067112Free PMC Article
Sun XS, Tao Y, Le Tourneau C, Pointreau Y, Sire C, Kaminsky MC, Coutte A, Alfonsi M, Boisselier P, Martin L, Miroir J, Ramee JF, Delord JP, Clatot F, Rolland F, Villa J, Magne N, Elicin O, Gherga E, Nguyen F, Lafond C, Bera G, Calugaru V, Geoffrois L, Chauffert B, Zubel A, Zanna C, Brienza S, Crompton P, Rouits E, Gollmer K, Szyldergemajn S, Bourhis J
Lancet Oncol 2020 Sep;21(9):1173-1187. Epub 2020 Aug 3 doi: 10.1016/S1470-2045(20)30327-2. PMID: 32758455
Qureshi HA, Abouyared M, Barber B, Houlton JJ
Curr Treat Options Oncol 2019 Apr 1;20(5):36. doi: 10.1007/s11864-019-0621-x. PMID: 30931485
Mehanna H, McConkey CC, Rahman JK, Wong WL, Smith AF, Nutting C, Hartley AG, Hall P, Hulme C, Patel DK, Zeidler SV, Robinson M, Sanghera B, Fresco L, Dunn JA
Health Technol Assess 2017 Apr;21(17):1-122. doi: 10.3310/hta21170. PMID: 28409743Free PMC Article

Clinical prediction guides

Ferris RL, Flamand Y, Weinstein GS, Li S, Quon H, Mehra R, Garcia JJ, Chung CH, Gillison ML, Duvvuri U, O'Malley BW Jr, Ozer E, Thomas GR, Koch WM, Gross ND, Bell RB, Saba NF, Lango M, Méndez E, Burtness B
J Clin Oncol 2022 Jan 10;40(2):138-149. Epub 2021 Oct 26 doi: 10.1200/JCO.21.01752. PMID: 34699271Free PMC Article
Parmar A, Macluskey M, Mc Goldrick N, Conway DI, Glenny AM, Clarkson JE, Worthington HV, Chan KK
Cochrane Database Syst Rev 2021 Dec 20;12(12):CD006386. doi: 10.1002/14651858.CD006386.pub4. PMID: 34929047Free PMC Article
Magnes T, Wagner S, Kiem D, Weiss L, Rinnerthaler G, Greil R, Melchardt T
Int J Mol Sci 2021 May 7;22(9) doi: 10.3390/ijms22094981. PMID: 34067112Free PMC Article
Qureshi HA, Abouyared M, Barber B, Houlton JJ
Curr Treat Options Oncol 2019 Apr 1;20(5):36. doi: 10.1007/s11864-019-0621-x. PMID: 30931485
Mehanna H, McConkey CC, Rahman JK, Wong WL, Smith AF, Nutting C, Hartley AG, Hall P, Hulme C, Patel DK, Zeidler SV, Robinson M, Sanghera B, Fresco L, Dunn JA
Health Technol Assess 2017 Apr;21(17):1-122. doi: 10.3310/hta21170. PMID: 28409743Free PMC Article

Recent systematic reviews

Faur CI, Falamas A, Chirila M, Roman RC, Rotaru H, Moldovan MA, Albu S, Baciut M, Robu I, Hedesiu M
Int J Oral Maxillofac Surg 2022 Nov;51(11):1373-1381. Epub 2022 Mar 10 doi: 10.1016/j.ijom.2022.02.015. PMID: 35282942
Parmar A, Macluskey M, Mc Goldrick N, Conway DI, Glenny AM, Clarkson JE, Worthington HV, Chan KK
Cochrane Database Syst Rev 2021 Dec 20;12(12):CD006386. doi: 10.1002/14651858.CD006386.pub4. PMID: 34929047Free PMC Article
Alterio D, Gugliandolo SG, Augugliaro M, Marvaso G, Gandini S, Bellerba F, Russell-Edu SW, De Simone I, Cinquini M, Starzyńska A, Zaffaroni M, Bacigalupo A, Fanetti G, Durante S, Dicuonzo S, Orecchia R, Jereczek-Fossa BA
Oral Dis 2021 Oct;27(7):1644-1653. Epub 2020 Sep 22 doi: 10.1111/odi.13599. PMID: 32810381
Jayaram SC, Muzaffar SJ, Ahmed I, Dhanda J, Paleri V, Mehanna H
Head Neck 2016 Dec;38(12):1855-1861. Epub 2016 Jul 13 doi: 10.1002/hed.24531. PMID: 27405247
Masterson L, Moualed D, Liu ZW, Howard JE, Dwivedi RC, Tysome JR, Benson R, Sterling JC, Sudhoff H, Jani P, Goon PK
Eur J Cancer 2014 Oct;50(15):2636-48. Epub 2014 Aug 1 doi: 10.1016/j.ejca.2014.07.001. PMID: 25091798

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