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Metastatic Rectal Squamous Cell Carcinoma

MedGen UID:
1736273
•Concept ID:
C5418788
•
Neoplastic Process

Definition

Rectal squamous cell carcinoma that has spread from the original site of growth to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Rectal Squamous Cell Carcinoma

Professional guidelines

PubMed

Squamous rectal carcinoma: a rare malignancy, literature review and management recommendations.
Astaras C, Bornand A, Koessler T
ESMO Open 2021 Aug;6(4):100180. Epub 2021 Jun 7 doi: 10.1016/j.esmoop.2021.100180. PMID: 34111760Free PMC Article
Long-standing Crohn's disease and its implication on anal squamous cell cancer management.
Lightner AL, Moncrief SB, Smyrk TC, Pemberton JH, Haddock MG, Larson DW, Dozois EJ, Mathis KL
Int J Colorectal Dis 2017 May;32(5):661-666. Epub 2017 Mar 14 doi: 10.1007/s00384-017-2794-8. PMID: 28293746
Chemoradiotherapy in the management of primary squamous-cell carcinoma of the rectum.
Wang ML, Heriot A, Leong T, Ngan SY
Colorectal Dis 2011 Mar;13(3):296-301. doi: 10.1111/j.1463-1318.2009.02154.x. PMID: 20002695

Recent clinical studies

Etiology

Anal Cancer and Anal Cancer Screening.
Cohen CM, Clarke MA
Clin Obstet Gynecol 2023 Sep 1;66(3):516-533. Epub 2023 Jul 13 doi: 10.1097/GRF.0000000000000789. PMID: 37439541Free PMC Article
Squamous rectal carcinoma: a rare malignancy, literature review and management recommendations.
Astaras C, Bornand A, Koessler T
ESMO Open 2021 Aug;6(4):100180. Epub 2021 Jun 7 doi: 10.1016/j.esmoop.2021.100180. PMID: 34111760Free PMC Article
Outcome following local excision of T1 anal cancers-a systematic review.
Pedersen TB, Kildsig J, Serup-Hansen E, Gocht-Jensen P, Klein MF
Int J Colorectal Dis 2020 Sep;35(9):1663-1671. Epub 2020 Jul 15 doi: 10.1007/s00384-020-03687-8. PMID: 32671458
Neoadjuvant Chemotherapy Followed by Radical Surgery Versus Concomitant Chemotherapy and Radiotherapy in Patients With Stage IB2, IIA, or IIB Squamous Cervical Cancer: A Randomized Controlled Trial.
Gupta S, Maheshwari A, Parab P, Mahantshetty U, Hawaldar R, Sastri Chopra S, Kerkar R, Engineer R, Tongaonkar H, Ghosh J, Gulia S, Kumar N, Shylasree TS, Gawade R, Kembhavi Y, Gaikar M, Menon S, Thakur M, Shrivastava S, Badwe R
J Clin Oncol 2018 Jun 1;36(16):1548-1555. Epub 2018 Feb 12 doi: 10.1200/JCO.2017.75.9985. PMID: 29432076
Anorectal Cancer: Critical Anatomic and Staging Distinctions That Affect Use of Radiation Therapy.
Matalon SA, Mamon HJ, Fuchs CS, Doyle LA, Tirumani SH, Ramaiya NH, Rosenthal MH
Radiographics 2015 Nov-Dec;35(7):2090-107. doi: 10.1148/rg.2015150037. PMID: 26562239Free PMC Article

Diagnosis

Anal Cancer and Anal Cancer Screening.
Cohen CM, Clarke MA
Clin Obstet Gynecol 2023 Sep 1;66(3):516-533. Epub 2023 Jul 13 doi: 10.1097/GRF.0000000000000789. PMID: 37439541Free PMC Article
Demographics, pattern of practice and clinical outcomes in rectal squamous cell carcinoma.
Id Said B, Buchan D, Liu Z, Kim J, Hosni A, Brierley JD, Chadi S, Grant RC, Kalimuthu S, Liu ZA, Lukovic J
Colorectal Dis 2023 Apr;25(4):608-615. Epub 2022 Nov 28 doi: 10.1111/codi.16417. PMID: 36394982
Squamous rectal carcinoma: a rare malignancy, literature review and management recommendations.
Astaras C, Bornand A, Koessler T
ESMO Open 2021 Aug;6(4):100180. Epub 2021 Jun 7 doi: 10.1016/j.esmoop.2021.100180. PMID: 34111760Free PMC Article
Squamous cell rectal cancer in a young woman.
Novisedláková M, Udovít Ml D, Oravský M, Kukučka M, Schnorrer M
Klin Onkol 2021 Winter;34(1):62-68. doi: 10.48095/ccko202162. PMID: 33657822
Tumors and Tumorlike Conditions of the Anal Canal and Perianal Region: MR Imaging Findings.
Surabhi VR, Menias CO, Amer AM, Elshikh M, Katabathina VS, Hara AK, Baughman WC, Kielar A, Elsayes KM, Siegel CL
Radiographics 2016 Sep-Oct;36(5):1339-53. doi: 10.1148/rg.2016150209. PMID: 27618320

Therapy

Anal Cancer and Anal Cancer Screening.
Cohen CM, Clarke MA
Clin Obstet Gynecol 2023 Sep 1;66(3):516-533. Epub 2023 Jul 13 doi: 10.1097/GRF.0000000000000789. PMID: 37439541Free PMC Article
Practice changing data and emerging concepts from recent radiation therapy randomised clinical trials.
Espenel S, Chargari C, Blanchard P, Bockel S, Morel D, Rivera S, Levy A, Deutsch E
Eur J Cancer 2022 Aug;171:242-258. Epub 2022 Jun 29 doi: 10.1016/j.ejca.2022.04.038. PMID: 35779346
Squamous rectal carcinoma: a rare malignancy, literature review and management recommendations.
Astaras C, Bornand A, Koessler T
ESMO Open 2021 Aug;6(4):100180. Epub 2021 Jun 7 doi: 10.1016/j.esmoop.2021.100180. PMID: 34111760Free PMC Article
Neoadjuvant Chemotherapy Followed by Radical Surgery Versus Concomitant Chemotherapy and Radiotherapy in Patients With Stage IB2, IIA, or IIB Squamous Cervical Cancer: A Randomized Controlled Trial.
Gupta S, Maheshwari A, Parab P, Mahantshetty U, Hawaldar R, Sastri Chopra S, Kerkar R, Engineer R, Tongaonkar H, Ghosh J, Gulia S, Kumar N, Shylasree TS, Gawade R, Kembhavi Y, Gaikar M, Menon S, Thakur M, Shrivastava S, Badwe R
J Clin Oncol 2018 Jun 1;36(16):1548-1555. Epub 2018 Feb 12 doi: 10.1200/JCO.2017.75.9985. PMID: 29432076
Squamous-cell carcinoma of the colon responsive to combination chemotherapy: report of two cases and review of the literature.
Juturi JV, Francis B, Koontz PW, Wilkes JD
Dis Colon Rectum 1999 Jan;42(1):102-9. doi: 10.1007/BF02235191. PMID: 10211528

Prognosis

Perianal Fistula-Associated Carcinoma in Crohn's Disease: A Multicentre Retrospective Case Control Study.
Palmieri C, Müller G, Kroesen AJ, Galata C, Rink AD, Morgenstern J, Kruis W
J Crohns Colitis 2021 Oct 7;15(10):1686-1693. doi: 10.1093/ecco-jcc/jjab057. PMID: 33772272
Neoadjuvant Chemotherapy Followed by Radical Surgery Versus Concomitant Chemotherapy and Radiotherapy in Patients With Stage IB2, IIA, or IIB Squamous Cervical Cancer: A Randomized Controlled Trial.
Gupta S, Maheshwari A, Parab P, Mahantshetty U, Hawaldar R, Sastri Chopra S, Kerkar R, Engineer R, Tongaonkar H, Ghosh J, Gulia S, Kumar N, Shylasree TS, Gawade R, Kembhavi Y, Gaikar M, Menon S, Thakur M, Shrivastava S, Badwe R
J Clin Oncol 2018 Jun 1;36(16):1548-1555. Epub 2018 Feb 12 doi: 10.1200/JCO.2017.75.9985. PMID: 29432076
Chemoradiotherapy in the management of primary squamous-cell carcinoma of the rectum.
Wang ML, Heriot A, Leong T, Ngan SY
Colorectal Dis 2011 Mar;13(3):296-301. doi: 10.1111/j.1463-1318.2009.02154.x. PMID: 20002695
Laparoscopic total mesorectal excision (TME) for rectal cancer surgery: long-term outcomes.
Leroy J, Jamali F, Forbes L, Smith M, Rubino F, Mutter D, Marescaux J
Surg Endosc 2004 Feb;18(2):281-9. Epub 2003 Dec 29 doi: 10.1007/s00464-002-8877-8. PMID: 14691716
Squamous-cell carcinoma of the colon responsive to combination chemotherapy: report of two cases and review of the literature.
Juturi JV, Francis B, Koontz PW, Wilkes JD
Dis Colon Rectum 1999 Jan;42(1):102-9. doi: 10.1007/BF02235191. PMID: 10211528

Clinical prediction guides

Demographics, pattern of practice and clinical outcomes in rectal squamous cell carcinoma.
Id Said B, Buchan D, Liu Z, Kim J, Hosni A, Brierley JD, Chadi S, Grant RC, Kalimuthu S, Liu ZA, Lukovic J
Colorectal Dis 2023 Apr;25(4):608-615. Epub 2022 Nov 28 doi: 10.1111/codi.16417. PMID: 36394982
Coexpress of GATA-3 and ER in Anorectal and Head and Neck Squamous Cell Carcinoma Mimicking Metastatic Breast Cancer.
Wang Y, Lu S, Amin A, Wang L
Appl Immunohistochem Mol Morphol 2021 Jul 1;29(6):409-413. doi: 10.1097/PAI.0000000000000887. PMID: 33264107
Adenosquamous Cell Carcinoma of the Rectum in a Girl: First Case Reported and Review of the Literature.
García NÁ, Hernando Cubero J, Alonso Orduña V, Torrecilla Idoipe N, Calvo Escribano C, Fernandez Atuán R
J Pediatr Hematol Oncol 2015 Aug;37(6):e364-7. doi: 10.1097/MPH.0000000000000361. PMID: 26181422
Impact of circumferential resection margin distance on locoregional recurrence and survival after chemoradiotherapy in esophageal squamous cell carcinoma.
Chao YK, Yeh CJ, Chang HK, Tseng CK, Chu YY, Hsieh MJ, Wu YC, Liu HP
Ann Surg Oncol 2011 Feb;18(2):529-34. Epub 2010 Aug 10 doi: 10.1245/s10434-010-1244-4. PMID: 20697822
Chemoradiotherapy in the management of primary squamous-cell carcinoma of the rectum.
Wang ML, Heriot A, Leong T, Ngan SY
Colorectal Dis 2011 Mar;13(3):296-301. doi: 10.1111/j.1463-1318.2009.02154.x. PMID: 20002695

Recent systematic reviews

Outcome following local excision of T1 anal cancers-a systematic review.
Pedersen TB, Kildsig J, Serup-Hansen E, Gocht-Jensen P, Klein MF
Int J Colorectal Dis 2020 Sep;35(9):1663-1671. Epub 2020 Jul 15 doi: 10.1007/s00384-020-03687-8. PMID: 32671458

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