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Benign Laryngeal Soft Tissue Neoplasm

MedGen UID:
1738967
•Concept ID:
C5420188
•
Neoplastic Process

Definition

A mesenchymal neoplasm that arises from the larynx and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Laryngeal Soft Tissue Neoplasm

Professional guidelines

PubMed

Office pulsed dye laser treatment for benign laryngeal vascular polyps: a preliminary study.
Ivey CM, Woo P, Altman KW, Shapshay SM
Ann Otol Rhinol Laryngol 2008 May;117(5):353-8. doi: 10.1177/000348940811700505. PMID: 18564532
Bronchoscopic management of benign stenosis.
Shapshay SM, Valdez TA
Chest Surg Clin N Am 2001 Nov;11(4):749-68. PMID: 11780294
Combined surgery and postoperative irradiation in the treatment of cervical lymph nodes.
Goffinet DR, Fee WE Jr, Goode RL
Arch Otolaryngol 1984 Nov;110(11):736-8. doi: 10.1001/archotol.1984.00800370038009. PMID: 6487124

Recent clinical studies

Etiology

Supraglottic subepithelial benign mass lesions: Focus on clinical features of sialolipoma-like lesion.
Tachibana T, Kariya S, Wani Y, Komatsubara Y, Naoi Y, Kuroda K, Fushimi S, Hotta M, Haruna K, Nagatani T, Makino T, Kataoka Y, Nishizaki K
Auris Nasus Larynx 2021 Feb;48(1):154-160. Epub 2020 Aug 15 doi: 10.1016/j.anl.2020.07.017. PMID: 32807554
Well-Differentiated/Dedifferentiated Liposarcoma Arising in the Upper Aerodigestive Tract: 8 Cases Mimicking Non-adipocytic Lesions.
Fritchie K, Ghosh T, Graham RP, Roden AC, Schembri-Wismayer D, Folpe A, Rivera M
Head Neck Pathol 2020 Dec;14(4):974-981. Epub 2020 May 14 doi: 10.1007/s12105-020-01171-x. PMID: 32410132Free PMC Article
Differing characteristics of cartilaginous lesions of the larynx.
Ferlito A, Devaney KO, Mäkitie AA
Eur Arch Otorhinolaryngol 2019 Oct;276(10):2635-2647. Epub 2019 Jul 23 doi: 10.1007/s00405-019-05563-w. PMID: 31338576Free PMC Article
Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: What is New in the 2017 WHO Blue Book for Tumours of the Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Gale N, Poljak M, Zidar N
Head Neck Pathol 2017 Mar;11(1):23-32. Epub 2017 Feb 28 doi: 10.1007/s12105-017-0788-z. PMID: 28247231Free PMC Article
Submucosal neoplasms of the laryngeal introitus.
Friedman AD, Burns JA, Lutch MJ, Zeitels SM
J Laryngol Otol 2012 Jul;126(7):706-13. Epub 2012 May 25 doi: 10.1017/S0022215112000928. PMID: 22624973

Diagnosis

Supraglottic subepithelial benign mass lesions: Focus on clinical features of sialolipoma-like lesion.
Tachibana T, Kariya S, Wani Y, Komatsubara Y, Naoi Y, Kuroda K, Fushimi S, Hotta M, Haruna K, Nagatani T, Makino T, Kataoka Y, Nishizaki K
Auris Nasus Larynx 2021 Feb;48(1):154-160. Epub 2020 Aug 15 doi: 10.1016/j.anl.2020.07.017. PMID: 32807554
Nonepithelial Tumors of the Larynx: Single-Institution 13-Year Review with Radiologic-Pathologic Correlation.
Ong AC, Huh EH, Moreland AJ, Rooper LM, Aygun N, Akst LM, Best SR, Khan MA
Radiographics 2020 Nov-Dec;40(7):2011-2028. Epub 2020 Oct 9 doi: 10.1148/rg.2020190210. PMID: 33035134
Differing characteristics of cartilaginous lesions of the larynx.
Ferlito A, Devaney KO, Mäkitie AA
Eur Arch Otorhinolaryngol 2019 Oct;276(10):2635-2647. Epub 2019 Jul 23 doi: 10.1007/s00405-019-05563-w. PMID: 31338576Free PMC Article
Buccal space tumours.
Hasan Z, Tan D, Buchanan M, Palme C, Riffat F
Auris Nasus Larynx 2019 Apr;46(2):160-166. Epub 2018 Jul 18 doi: 10.1016/j.anl.2018.06.011. PMID: 30031665
Hyperbaric oxygen and malignancies: a potential role in radiotherapy, chemotherapy, tumor surgery and phototherapy.
Al-Waili NS, Butler GJ, Beale J, Hamilton RW, Lee BY, Lucas P
Med Sci Monit 2005 Sep;11(9):RA279-89. Epub 2005 Aug 26 PMID: 16127374

Therapy

Office pulsed dye laser treatment for benign laryngeal vascular polyps: a preliminary study.
Ivey CM, Woo P, Altman KW, Shapshay SM
Ann Otol Rhinol Laryngol 2008 May;117(5):353-8. doi: 10.1177/000348940811700505. PMID: 18564532
Atypical fibroxanthoma of the external ear in a cardiac transplant recipient: case report and the causal role of the immunosuppressive therapy.
Ferri E, Iaderosa GA, Armato E
Auris Nasus Larynx 2008 Jun;35(2):260-3. Epub 2007 Sep 5 doi: 10.1016/j.anl.2007.04.013. PMID: 17804184
Bronchoscopic management of benign stenosis.
Shapshay SM, Valdez TA
Chest Surg Clin N Am 2001 Nov;11(4):749-68. PMID: 11780294
Can positron emission tomography distinguish tumor recurrence from irradiation sequelae in patients treated for larynx cancer?
Greven KM, Williams DW 3rd, Keyes JW Jr, McGuirt WF, Watson NE Jr, Case LD
Cancer J Sci Am 1997 Nov-Dec;3(6):353-7. PMID: 9403048
Distinguishing tumor recurrence from irradiation sequelae with positron emission tomography in patients treated for larynx cancer.
Greven KM, Williams DW 3rd, Keyes JW Jr, McGuirt WF, Harkness BA, Watson NE Jr, Raben M, Frazier LC, Geisinger KR, Cappellari JO
Int J Radiat Oncol Biol Phys 1994 Jul 1;29(4):841-5. doi: 10.1016/0360-3016(94)90574-6. PMID: 8040032

Prognosis

Differing characteristics of cartilaginous lesions of the larynx.
Ferlito A, Devaney KO, Mäkitie AA
Eur Arch Otorhinolaryngol 2019 Oct;276(10):2635-2647. Epub 2019 Jul 23 doi: 10.1007/s00405-019-05563-w. PMID: 31338576Free PMC Article
Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: What is New in the 2017 WHO Blue Book for Tumours of the Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Gale N, Poljak M, Zidar N
Head Neck Pathol 2017 Mar;11(1):23-32. Epub 2017 Feb 28 doi: 10.1007/s12105-017-0788-z. PMID: 28247231Free PMC Article
Submucosal neoplasms of the laryngeal introitus.
Friedman AD, Burns JA, Lutch MJ, Zeitels SM
J Laryngol Otol 2012 Jul;126(7):706-13. Epub 2012 May 25 doi: 10.1017/S0022215112000928. PMID: 22624973
Cutaneous myoepithelioma: an under-recognized cutaneous neoplasm composed of myoepithelial cells.
Kutzner H, Mentzel T, Kaddu S, Soares LM, Sangueza OP, Requena L
Am J Surg Pathol 2001 Mar;25(3):348-55. doi: 10.1097/00000478-200103000-00009. PMID: 11224605
The pathology of head and neck tumors: spindle cell lesions (sarcomatoid carcinomas, nodular fasciitis, and fibrosarcoma) of the aerodigestive tracts, Part 14.
Batsakis JG, Rice DH, Howard DR
Head Neck Surg 1982 Jul-Aug;4(6):499-513. doi: 10.1002/hed.2890040609. PMID: 6749762

Clinical prediction guides

Osteoclast-Like Giant Cell Tumor of the Parotid Gland: Report of a Case Diagnosed on Fine-Needle Aspiration Cytology With Histological and Immunohistochemical Findings.
Elhence P, Rao M, Goyal A, Kumar A, Khera PS, Bhattacharya S
Diagn Cytopathol 2016 Jun;44(6):548-51. Epub 2016 Apr 15 doi: 10.1002/dc.23482. PMID: 27079183
Non-epithelial neoplasms of the larynx and hypopharynx - 12 - years of experience.
Rzepakowska A, Osuch-Wójcikiewicz E, Bruzgielewicz A, Niemczyk K
Otolaryngol Pol 2015;69(5):9-15. doi: 10.5604/00306657.1170420. PMID: 26537641
A case report of a rare intramuscular granular cell tumor.
Porta N, Mazzitelli R, Cacciotti J, Cirenza M, Labate A, Lo Schiavo MG, Laghi A, Petrozza V, Della Rocca C
Diagn Pathol 2015 Sep 17;10:162. doi: 10.1186/s13000-015-0390-1. PMID: 26377191Free PMC Article
Intramuscular myxoma of scalene muscle: a case report.
Ozawa H, Fujii M, Tomita T, Ogawa K
Auris Nasus Larynx 2004 Sep;31(3):319-22. doi: 10.1016/j.anl.2004.03.009. PMID: 15364372
Neurogenic tumors of the head and neck in children.
de Campora E, Radici M, de Campora L
Int J Pediatr Otorhinolaryngol 1999 Oct 5;49 Suppl 1:S231-3. doi: 10.1016/s0165-5876(99)00166-4. PMID: 10577811

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