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Supratentorial Gliosarcoma

MedGen UID:
1739476
•Concept ID:
C5418951
•
Neoplastic Process

Definition

A gliosarcoma arising from the supratentorial region. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSupratentorial Gliosarcoma

Recent clinical studies

Etiology

Cerebellar high-grade gliomas do not present the same molecular alterations as supratentorial high-grade gliomas and may show histone H3 gene mutations.
Tauziède-Espariat A, Saffroy R, Pagès M, Pallud J, Legrand L, Besnard A, Lacombe J, Lot G, Borha A, Tazi S, Adle-Biassette H, Polivka M, Lechapt E, Varlet P
Clin Neuropathol 2018 Sep/Oct;37(5):209-216. doi: 10.5414/NP301104. PMID: 29809131
Detailed magnetic resonance imaging features of a case series of primary gliosarcoma.
Sampaio L, Linhares P, Fonseca J
Neuroradiol J 2017 Dec;30(6):546-553. Epub 2017 Jun 23 doi: 10.1177/1971400917715879. PMID: 28644110Free PMC Article
Radiotherapy in supratentorial gliomas. A study of 821 cases.
Heesters M, Molenaar W, Go GK
Strahlenther Onkol 2003 Sep;179(9):606-14. doi: 10.1007/s00066-003-1098-9. PMID: 14628126
Gliosarcoma: a clinical study.
Lutterbach J, Guttenberger R, Pagenstecher A
Radiother Oncol 2001 Oct;61(1):57-64. doi: 10.1016/s0167-8140(01)00415-7. PMID: 11578729
Characterisation of molecular alterations in microdissected archival gliomas.
Walker C, Joyce KA, Thompson-Hehir J, Davies MP, Gibbs FE, Halliwell N, Lloyd BH, Machell Y, Roebuck MM, Salisbury J, Sibson DR, Du Plessis D, Broome J, Rossi ML
Acta Neuropathol 2001 Apr;101(4):321-33. doi: 10.1007/s004010000259. PMID: 11355303

Diagnosis

Genetic and histologic spatiotemporal evolution of recurrent, multifocal, multicentric and metastatic glioblastoma.
Georgescu MM, Olar A
Acta Neuropathol Commun 2020 Feb 3;8(1):10. doi: 10.1186/s40478-020-0889-x. PMID: 32014051Free PMC Article
Detailed magnetic resonance imaging features of a case series of primary gliosarcoma.
Sampaio L, Linhares P, Fonseca J
Neuroradiol J 2017 Dec;30(6):546-553. Epub 2017 Jun 23 doi: 10.1177/1971400917715879. PMID: 28644110Free PMC Article
Gliosarcoma of the cerebellar hemisphere: a case report and review of the literature.
Moon SK, Kim EJ, Choi WS, Ryu CW, Park BJ, Lee J
Korean J Radiol 2010 Sep-Oct;11(5):566-70. Epub 2010 Aug 27 doi: 10.3348/kjr.2010.11.5.566. PMID: 20808702Free PMC Article
Characterisation of molecular alterations in microdissected archival gliomas.
Walker C, Joyce KA, Thompson-Hehir J, Davies MP, Gibbs FE, Halliwell N, Lloyd BH, Machell Y, Roebuck MM, Salisbury J, Sibson DR, Du Plessis D, Broome J, Rossi ML
Acta Neuropathol 2001 Apr;101(4):321-33. doi: 10.1007/s004010000259. PMID: 11355303
Associated vascular malformations and neoplasms in children.
Ecklund J, Schut L, Rorke L
Pediatr Neurosurg 1993 Jul-Aug;19(4):196-201. doi: 10.1159/000120730. PMID: 8329304

Therapy

Clinical outcome of gliosarcoma compared with glioblastoma multiforme: North Central Cancer Treatment Group results.
Galanis E, Buckner JC, Dinapoli RP, Scheithauer BW, Jenkins RB, Wang CH, O'Fallon JR, Farr G Jr
J Neurosurg 1998 Sep;89(3):425-30. doi: 10.3171/jns.1998.89.3.0425. PMID: 9724117
Combination chemotherapy (COMP protocol) and radiotherapy of anaplastic supratentorial gliomas.
Jellinger K, Kothbauer P, Volc D, Vollmer R, Weiss R
Acta Neurochir (Wien) 1979;51(1-2):1-13. doi: 10.1007/BF01401790. PMID: 532722

Prognosis

Gliosarcoma in a Young Filipino Woman: A Case Report and Review of the Literature.
Langlois AM, Alarfaj AK, Sagga A, Findlay JM, Das S
Am J Case Rep 2019 Jun 27;20:914-919. doi: 10.12659/AJCR.916020. PMID: 31243260Free PMC Article
Clinical outcome of gliosarcoma compared with glioblastoma multiforme: a clinical study in Chinese patients.
Zhang G, Huang S, Zhang J, Wu Z, Lin S, Wang Y
J Neurooncol 2016 Apr;127(2):355-62. Epub 2016 Jan 2 doi: 10.1007/s11060-015-2046-0. PMID: 26725096
Radiotherapy in supratentorial gliomas. A study of 821 cases.
Heesters M, Molenaar W, Go GK
Strahlenther Onkol 2003 Sep;179(9):606-14. doi: 10.1007/s00066-003-1098-9. PMID: 14628126
Gliosarcoma: a clinical study.
Lutterbach J, Guttenberger R, Pagenstecher A
Radiother Oncol 2001 Oct;61(1):57-64. doi: 10.1016/s0167-8140(01)00415-7. PMID: 11578729
Clinical outcome of gliosarcoma compared with glioblastoma multiforme: North Central Cancer Treatment Group results.
Galanis E, Buckner JC, Dinapoli RP, Scheithauer BW, Jenkins RB, Wang CH, O'Fallon JR, Farr G Jr
J Neurosurg 1998 Sep;89(3):425-30. doi: 10.3171/jns.1998.89.3.0425. PMID: 9724117

Clinical prediction guides

Magnetic resonance imaging of primary cerebral gliosarcoma: a report of 15 cases.
Han L, Zhang X, Qiu S, Li X, Xiong W, Zhang Y, Qu H, Chang R, Chen B, Wang W, Li S
Acta Radiol 2008 Nov;49(9):1058-67. doi: 10.1080/02841850802314796. PMID: 18766496
Radiotherapy in supratentorial gliomas. A study of 821 cases.
Heesters M, Molenaar W, Go GK
Strahlenther Onkol 2003 Sep;179(9):606-14. doi: 10.1007/s00066-003-1098-9. PMID: 14628126
Expression of the neural cell adhesion molecule in astrocytic tumors: an inverse correlation with malignancy.
Sasaki H, Yoshida K, Ikeda E, Asou H, Inaba M, Otani M, Kawase T
Cancer 1998 May 15;82(10):1921-31. doi: 10.1002/(sici)1097-0142(19980515)82:10<1921::aid-cncr16>3.0.co;2-v. PMID: 9587126
Linear contrast enhancement at the operative site on early post-operative CT after removal of brain tumors.
Nicoletti GF, Barone F, Passanisi M, Mancuso P, Albanese V
J Neurosurg Sci 1994 Jun;38(2):131-5. PMID: 7891195

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