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Unresectable Neuroendocrine Carcinoma

MedGen UID:
1744762
Concept ID:
C5419869
Neoplastic Process

Definition

Neuroendocrine carcinoma that is not amenable to surgical resection. [from NCI]

Professional guidelines

PubMed

Bellefkih FZ, Benchakroun N, Lalya I, Amaoui B, El Kacemi H, Acharki A, El Hfid M, El Mazghi A, Chekrine T, Bouchbika Z, Jouhadi H, Sahraoui S, Tawfiq N, Michalet M
Cancer Radiother 2023 Sep;27(6-7):622-637. Epub 2023 Jul 25 doi: 10.1016/j.canrad.2023.06.010. PMID: 37500390
Chatani PD, Agarwal SK, Sadowski SM
Front Endocrinol (Lausanne) 2020;11:575620. Epub 2021 Jan 18 doi: 10.3389/fendo.2020.575620. PMID: 33537001Free PMC Article
Pappa T, Alevizaki M
Endocrine 2016 Jul;53(1):7-17. Epub 2016 Feb 2 doi: 10.1007/s12020-016-0873-1. PMID: 26839093

Recent clinical studies

Etiology

Kim S, Wuthrick E, Blakaj D, Eroglu Z, Verschraegen C, Thapa R, Mills M, Dibs K, Liveringhouse C, Russell J, Caudell JJ, Tarhini A, Markowitz J, Kendra K, Wu R, Chen DT, Berglund A, Michael L, Aoki M, Wang MH, Hamaidi I, Cheng P, de la Iglesia J, Slebos RJ, Chung CH, Knepper TC, Moran-Segura CM, Nguyen JV, Perez BA, Rose T, Harrison L, Messina JL, Sondak VK, Tsai KY, Khushalani NI, Brohl AS
Lancet 2022 Sep 24;400(10357):1008-1019. Epub 2022 Sep 12 doi: 10.1016/S0140-6736(22)01659-2. PMID: 36108657Free PMC Article
Morizane C, Machida N, Honma Y, Okusaka T, Boku N, Kato K, Nomura S, Hiraoka N, Sekine S, Taniguchi H, Okano N, Yamaguchi K, Sato T, Ikeda M, Mizuno N, Ozaka M, Kataoka T, Ueno M, Kitagawa Y, Terashima M, Furuse J; Japan Clinical Oncology Group (JCOG)
JAMA Oncol 2022 Oct 1;8(10):1447-1455. doi: 10.1001/jamaoncol.2022.3395. PMID: 35980649Free PMC Article
Hasskarl J
Recent Results Cancer Res 2018;211:101-123. doi: 10.1007/978-3-319-91442-8_8. PMID: 30069763
Haberal Reyhan N
Exp Clin Transplant 2017 Mar;15(Suppl 2):69-73. doi: 10.6002/ect.TOND16.L18. PMID: 28302003
Eghtesad B, Aucejo F
J Gastrointest Cancer 2014 Sep;45(3):353-62. doi: 10.1007/s12029-014-9590-2. PMID: 24604263

Diagnosis

Ziogas IA, Schmitz R, Moris D, Vatsaas CJ
Anticancer Res 2022 Feb;42(2):629-639. doi: 10.21873/anticanres.15520. PMID: 35093860
Omiyale AO
World J Gastroenterol 2021 Jul 14;27(26):4172-4181. doi: 10.3748/wjg.v27.i26.4172. PMID: 34326617Free PMC Article
Lanfredini S, Thapa A, O'Neill E
Biochem Soc Trans 2019 Aug 30;47(4):961-972. Epub 2019 Jul 24 doi: 10.1042/BST20170521. PMID: 31341034
Pappa T, Alevizaki M
Endocrine 2016 Jul;53(1):7-17. Epub 2016 Feb 2 doi: 10.1007/s12020-016-0873-1. PMID: 26839093
Lebbe C, Becker JC, Grob JJ, Malvehy J, Del Marmol V, Pehamberger H, Peris K, Saiag P, Middleton MR, Bastholt L, Testori A, Stratigos A, Garbe C; European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organization for Research and Treatment of Cancer (EORTC)
Eur J Cancer 2015 Nov;51(16):2396-403. Epub 2015 Aug 6 doi: 10.1016/j.ejca.2015.06.131. PMID: 26257075

Therapy

Kim S, Wuthrick E, Blakaj D, Eroglu Z, Verschraegen C, Thapa R, Mills M, Dibs K, Liveringhouse C, Russell J, Caudell JJ, Tarhini A, Markowitz J, Kendra K, Wu R, Chen DT, Berglund A, Michael L, Aoki M, Wang MH, Hamaidi I, Cheng P, de la Iglesia J, Slebos RJ, Chung CH, Knepper TC, Moran-Segura CM, Nguyen JV, Perez BA, Rose T, Harrison L, Messina JL, Sondak VK, Tsai KY, Khushalani NI, Brohl AS
Lancet 2022 Sep 24;400(10357):1008-1019. Epub 2022 Sep 12 doi: 10.1016/S0140-6736(22)01659-2. PMID: 36108657Free PMC Article
Morizane C, Machida N, Honma Y, Okusaka T, Boku N, Kato K, Nomura S, Hiraoka N, Sekine S, Taniguchi H, Okano N, Yamaguchi K, Sato T, Ikeda M, Mizuno N, Ozaka M, Kataoka T, Ueno M, Kitagawa Y, Terashima M, Furuse J; Japan Clinical Oncology Group (JCOG)
JAMA Oncol 2022 Oct 1;8(10):1447-1455. doi: 10.1001/jamaoncol.2022.3395. PMID: 35980649Free PMC Article
Angeles CV, Sabel MS
J Surg Oncol 2021 Mar;123(3):775-781. doi: 10.1002/jso.26319. PMID: 33595894
Marabelle A, Le DT, Ascierto PA, Di Giacomo AM, De Jesus-Acosta A, Delord JP, Geva R, Gottfried M, Penel N, Hansen AR, Piha-Paul SA, Doi T, Gao B, Chung HC, Lopez-Martin J, Bang YJ, Frommer RS, Shah M, Ghori R, Joe AK, Pruitt SK, Diaz LA Jr
J Clin Oncol 2020 Jan 1;38(1):1-10. Epub 2019 Nov 4 doi: 10.1200/JCO.19.02105. PMID: 31682550Free PMC Article
Lee AY, Berman RS
Ann Surg Oncol 2020 Jan;27(1):22-27. Epub 2019 Sep 23 doi: 10.1245/s10434-019-07831-9. PMID: 31549317

Prognosis

Melehy A, Agopian V
Curr Opin Organ Transplant 2024 Feb 1;29(1):30-36. Epub 2023 Oct 18 doi: 10.1097/MOT.0000000000001118. PMID: 37851086
Sun TY, Hendifar A, Padda SK
Curr Oncol Rep 2022 Jul;24(7):819-824. Epub 2022 Mar 19 doi: 10.1007/s11912-022-01253-9. PMID: 35305210
Ziogas IA, Schmitz R, Moris D, Vatsaas CJ
Anticancer Res 2022 Feb;42(2):629-639. doi: 10.21873/anticanres.15520. PMID: 35093860
Raiker R, Chauhan A, Hasanein H, Burkeen G, Horn M, Veedu J, Vela C, Arnold S, Kolesar J, Anthony L, Evers BM, Cavnar M
Orphanet J Rare Dis 2019 Nov 21;14(1):266. doi: 10.1186/s13023-019-1230-2. PMID: 31752927Free PMC Article
Pappa T, Alevizaki M
Endocrine 2016 Jul;53(1):7-17. Epub 2016 Feb 2 doi: 10.1007/s12020-016-0873-1. PMID: 26839093

Clinical prediction guides

Melehy A, Agopian V
Curr Opin Organ Transplant 2024 Feb 1;29(1):30-36. Epub 2023 Oct 18 doi: 10.1097/MOT.0000000000001118. PMID: 37851086
Kim S, Wuthrick E, Blakaj D, Eroglu Z, Verschraegen C, Thapa R, Mills M, Dibs K, Liveringhouse C, Russell J, Caudell JJ, Tarhini A, Markowitz J, Kendra K, Wu R, Chen DT, Berglund A, Michael L, Aoki M, Wang MH, Hamaidi I, Cheng P, de la Iglesia J, Slebos RJ, Chung CH, Knepper TC, Moran-Segura CM, Nguyen JV, Perez BA, Rose T, Harrison L, Messina JL, Sondak VK, Tsai KY, Khushalani NI, Brohl AS
Lancet 2022 Sep 24;400(10357):1008-1019. Epub 2022 Sep 12 doi: 10.1016/S0140-6736(22)01659-2. PMID: 36108657Free PMC Article
Sun TY, Hendifar A, Padda SK
Curr Oncol Rep 2022 Jul;24(7):819-824. Epub 2022 Mar 19 doi: 10.1007/s11912-022-01253-9. PMID: 35305210
Vogel A, Gupta S, Zeile M, von Haken R, Brüning R, Lotz G, Vahrmeijer A, Vogl T, Wacker F
Adv Ther 2017 Jan;33(12):2122-2138. Epub 2016 Oct 31 doi: 10.1007/s12325-016-0424-4. PMID: 27798773Free PMC Article
Gillenwater AM, Weber RS
Cancer Treat Res 1997;90:149-69. doi: 10.1007/978-1-4615-6165-1_8. PMID: 9367082

Recent systematic reviews

Bellefkih FZ, Benchakroun N, Lalya I, Amaoui B, El Kacemi H, Acharki A, El Hfid M, El Mazghi A, Chekrine T, Bouchbika Z, Jouhadi H, Sahraoui S, Tawfiq N, Michalet M
Cancer Radiother 2023 Sep;27(6-7):622-637. Epub 2023 Jul 25 doi: 10.1016/j.canrad.2023.06.010. PMID: 37500390
Rowell NP
Br J Radiol 2023 Aug;96(1148):20220660. Epub 2023 Jun 29 doi: 10.1259/bjr.20220660. PMID: 37335288Free PMC Article
Tappenden P, Carroll C, Hamilton J, Kaltenthaler E, Wong R, Wadsley J, Moss L, Balasubramanian S
Health Technol Assess 2019 Feb;23(8):1-144. doi: 10.3310/hta23080. PMID: 30821231Free PMC Article
Vogel A, Gupta S, Zeile M, von Haken R, Brüning R, Lotz G, Vahrmeijer A, Vogl T, Wacker F
Adv Ther 2017 Jan;33(12):2122-2138. Epub 2016 Oct 31 doi: 10.1007/s12325-016-0424-4. PMID: 27798773Free PMC Article
Rosen AC, Wu S, Damse A, Sherman E, Lacouture ME
J Clin Endocrinol Metab 2012 Apr;97(4):1125-33. Epub 2012 Feb 29 doi: 10.1210/jc.2011-2677. PMID: 22378813

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