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Advanced Transformed Non-Hodgkin Lymphoma

MedGen UID:
1747774
Concept ID:
C5419608
Neoplastic Process

Definition

Transformed non-Hodgkin lymphoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Transformed Non-Hodgkin Lymphoma

Professional guidelines

PubMed

Nastoupil LJ, Bartlett NL
J Clin Oncol 2023 Feb 1;41(4):903-913. Epub 2022 Dec 12 doi: 10.1200/JCO.22.01848. PMID: 36508700
Jain P, Wang M
Am J Hematol 2019 Jun;94(6):710-725. Epub 2019 Apr 19 doi: 10.1002/ajh.25487. PMID: 30963600
El-Galaly TC, Villa D, Gormsen LC, Baech J, Lo A, Cheah CY
J Intern Med 2018 Oct;284(4):358-376. Epub 2018 Jul 24 doi: 10.1111/joim.12813. PMID: 29989234

Recent clinical studies

Etiology

Parry EM, Ten Hacken E, Wu CJ
Blood 2023 Jul 6;142(1):11-22. doi: 10.1182/blood.2022016502. PMID: 36758208Free PMC Article
Nastoupil LJ, Bartlett NL
J Clin Oncol 2023 Feb 1;41(4):903-913. Epub 2022 Dec 12 doi: 10.1200/JCO.22.01848. PMID: 36508700
El-Galaly TC, Villa D, Gormsen LC, Baech J, Lo A, Cheah CY
J Intern Med 2018 Oct;284(4):358-376. Epub 2018 Jul 24 doi: 10.1111/joim.12813. PMID: 29989234
Italiano A, Soria JC, Toulmonde M, Michot JM, Lucchesi C, Varga A, Coindre JM, Blakemore SJ, Clawson A, Suttle B, McDonald AA, Woodruff M, Ribich S, Hedrick E, Keilhack H, Thomson B, Owa T, Copeland RA, Ho PTC, Ribrag V
Lancet Oncol 2018 May;19(5):649-659. Epub 2018 Apr 9 doi: 10.1016/S1470-2045(18)30145-1. PMID: 29650362
Maloney DG
Curr Opin Hematol 1995 Jul;2(4):255-61. doi: 10.1097/00062752-199502040-00004. PMID: 9372005

Diagnosis

Parry EM, Ten Hacken E, Wu CJ
Blood 2023 Jul 6;142(1):11-22. doi: 10.1182/blood.2022016502. PMID: 36758208Free PMC Article
Wang H, Fu BB, Gale RP, Liang Y
Leukemia 2021 Sep;35(9):2460-2468. Epub 2021 Jun 11 doi: 10.1038/s41375-021-01313-2. PMID: 34117356Free PMC Article
Jain P, Wang M
Am J Hematol 2019 Jun;94(6):710-725. Epub 2019 Apr 19 doi: 10.1002/ajh.25487. PMID: 30963600
El-Galaly TC, Villa D, Gormsen LC, Baech J, Lo A, Cheah CY
J Intern Med 2018 Oct;284(4):358-376. Epub 2018 Jul 24 doi: 10.1111/joim.12813. PMID: 29989234
Jawed SI, Myskowski PL, Horwitz S, Moskowitz A, Querfeld C
J Am Acad Dermatol 2014 Feb;70(2):205.e1-16; quiz 221-2. doi: 10.1016/j.jaad.2013.07.049. PMID: 24438969

Therapy

Christensen BW, Zaha VG, Awan FT
Expert Rev Hematol 2022 Apr;15(4):321-331. Epub 2022 Apr 22 doi: 10.1080/17474086.2022.2067526. PMID: 35437106
Wang H, Fu BB, Gale RP, Liang Y
Leukemia 2021 Sep;35(9):2460-2468. Epub 2021 Jun 11 doi: 10.1038/s41375-021-01313-2. PMID: 34117356Free PMC Article
Huang R, Li X, He Y, Zhu W, Gao L, Liu Y, Gao L, Wen Q, Zhong JF, Zhang C, Zhang X
J Hematol Oncol 2020 Jul 2;13(1):86. doi: 10.1186/s13045-020-00910-5. PMID: 32616000Free PMC Article
Jain P, Wang M
Am J Hematol 2019 Jun;94(6):710-725. Epub 2019 Apr 19 doi: 10.1002/ajh.25487. PMID: 30963600
Xu-Monette ZY, Zhou J, Young KH
Blood 2018 Jan 4;131(1):68-83. Epub 2017 Nov 8 doi: 10.1182/blood-2017-07-740993. PMID: 29118007Free PMC Article

Prognosis

Nadeu F, Royo R, Massoni-Badosa R, Playa-Albinyana H, Garcia-Torre B, Duran-Ferrer M, Dawson KJ, Kulis M, Diaz-Navarro A, Villamor N, Melero JL, Chapaprieta V, Dueso-Barroso A, Delgado J, Moia R, Ruiz-Gil S, Marchese D, Giró A, Verdaguer-Dot N, Romo M, Clot G, Rozman M, Frigola G, Rivas-Delgado A, Baumann T, Alcoceba M, González M, Climent F, Abrisqueta P, Castellví J, Bosch F, Aymerich M, Enjuanes A, Ruiz-Gaspà S, López-Guillermo A, Jares P, Beà S, Capella-Gutierrez S, Gelpí JL, López-Bigas N, Torrents D, Campbell PJ, Gut I, Rossi D, Gaidano G, Puente XS, Garcia-Roves PM, Colomer D, Heyn H, Maura F, Martín-Subero JI, Campo E
Nat Med 2022 Aug;28(8):1662-1671. Epub 2022 Aug 11 doi: 10.1038/s41591-022-01927-8. PMID: 35953718Free PMC Article
Wang H, Fu BB, Gale RP, Liang Y
Leukemia 2021 Sep;35(9):2460-2468. Epub 2021 Jun 11 doi: 10.1038/s41375-021-01313-2. PMID: 34117356Free PMC Article
Jain P, Wang M
Am J Hematol 2019 Jun;94(6):710-725. Epub 2019 Apr 19 doi: 10.1002/ajh.25487. PMID: 30963600
El-Galaly TC, Villa D, Gormsen LC, Baech J, Lo A, Cheah CY
J Intern Med 2018 Oct;284(4):358-376. Epub 2018 Jul 24 doi: 10.1111/joim.12813. PMID: 29989234
Xu-Monette ZY, Zhou J, Young KH
Blood 2018 Jan 4;131(1):68-83. Epub 2017 Nov 8 doi: 10.1182/blood-2017-07-740993. PMID: 29118007Free PMC Article

Clinical prediction guides

Wang H, Fu BB, Gale RP, Liang Y
Leukemia 2021 Sep;35(9):2460-2468. Epub 2021 Jun 11 doi: 10.1038/s41375-021-01313-2. PMID: 34117356Free PMC Article
Jain P, Wang M
Am J Hematol 2019 Jun;94(6):710-725. Epub 2019 Apr 19 doi: 10.1002/ajh.25487. PMID: 30963600
El-Galaly TC, Villa D, Gormsen LC, Baech J, Lo A, Cheah CY
J Intern Med 2018 Oct;284(4):358-376. Epub 2018 Jul 24 doi: 10.1111/joim.12813. PMID: 29989234
Italiano A, Soria JC, Toulmonde M, Michot JM, Lucchesi C, Varga A, Coindre JM, Blakemore SJ, Clawson A, Suttle B, McDonald AA, Woodruff M, Ribich S, Hedrick E, Keilhack H, Thomson B, Owa T, Copeland RA, Ho PTC, Ribrag V
Lancet Oncol 2018 May;19(5):649-659. Epub 2018 Apr 9 doi: 10.1016/S1470-2045(18)30145-1. PMID: 29650362
Xu-Monette ZY, Zhou J, Young KH
Blood 2018 Jan 4;131(1):68-83. Epub 2017 Nov 8 doi: 10.1182/blood-2017-07-740993. PMID: 29118007Free PMC Article

Recent systematic reviews

Travaglino A, Russo D, Varricchio S, Pignatiello S, Baldo A, Picardi M, Pane F, Mascolo M
Am J Clin Pathol 2021 Aug 4;156(3):350-355. doi: 10.1093/ajcp/aqaa261. PMID: 33769436
Leberfinger AN, Behar BJ, Williams NC, Rakszawski KL, Potochny JD, Mackay DR, Ravnic DJ
JAMA Surg 2017 Dec 1;152(12):1161-1168. doi: 10.1001/jamasurg.2017.4026. PMID: 29049466

Supplemental Content

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