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Pancreatic Poorly Cohesive Adenocarcinoma

MedGen UID:
1754718
Concept ID:
C5419872
Neoplastic Process

Definition

An adenocarcinoma that arises from the pancreas and is characterized by the presence of isolated malignant cells or malignant cells that form small aggregates. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPancreatic Poorly Cohesive Adenocarcinoma

Recent clinical studies

Etiology

Simbolo M, Silvestris N, Malleo G, Mafficini A, Maggino L, Cocomazzi A, Veghini L, Mombello A, Pezzini F, Sereni E, Martelli FM, Gkountakos A, Ciaparrone C, Piredda ML, Ingravallo G, Paolino G, Nappo F, Rapposelli IG, Frassinetti L, Saragoni L, Lonardi S, Pea A, Paiella S, Fassan M, Brunetti O, Cingarlini S, Salvia R, Milella M, Corbo V, Lawlor RT, Scarpa A, Luchini C
Mod Pathol 2023 Sep;36(9):100251. Epub 2023 Jun 22 doi: 10.1016/j.modpat.2023.100251. PMID: 37355152
Wang Y, Li X, Gao L, Wang C, Zhang Y, Huang Q
BMC Gastroenterol 2020 Oct 21;20(1):351. doi: 10.1186/s12876-020-01498-3. PMID: 33087057Free PMC Article
Xue Y, Reid MD
Surg Pathol Clin 2020 Sep;13(3):453-467. Epub 2020 Jul 15 doi: 10.1016/j.path.2020.05.005. PMID: 32773194
Chang F, Vu C, Chandra A, Meenan J, Herbert A
Cytopathology 2006 Feb;17(1):10-7. doi: 10.1111/j.1365-2303.2006.00311.x. PMID: 16417560
Jiménez-Heffernan JA, Vicandi B, López-Ferrer P, González-Peramato P, Pérez-Campos A, Viguer JM
Acta Cytol 2004 May-Jun;48(3):295-301. doi: 10.1159/000326376. PMID: 15192942

Diagnosis

Bazzichetto C, Luchini C, Conciatori F, Vaccaro V, Di Cello I, Mattiolo P, Falcone I, Ferretti G, Scarpa A, Cognetti F, Milella M
Int J Mol Sci 2020 Nov 22;21(22) doi: 10.3390/ijms21228841. PMID: 33266496Free PMC Article
Xue Y, Reid MD
Surg Pathol Clin 2020 Sep;13(3):453-467. Epub 2020 Jul 15 doi: 10.1016/j.path.2020.05.005. PMID: 32773194
Hirabayashi K, Zamboni G, Ito H, Ogawa M, Kawaguchi Y, Yamashita T, Nakagohri T, Nakamura N
World J Gastroenterol 2013 Jun 7;19(21):3358-63. doi: 10.3748/wjg.v19.i21.3358. PMID: 23745041Free PMC Article
Cho YM, Choi J, Lee OJ, Lee HI, Han DJ, Ro JY
Pathol Int 2006 Nov;56(11):702-6. doi: 10.1111/j.1440-1827.2006.02033.x. PMID: 17040295
Tschang TP, Garza-Garza R, Kissane JM
Cancer 1977 May;39(5):2114-26. doi: 10.1002/1097-0142(197705)39:5<2114::aid-cncr2820390528>3.0.co;2-3. PMID: 870168

Therapy

Fonseca MR, Constante M, Moura A, Melo Valadão I
BMJ Case Rep 2019 Dec 2;12(12) doi: 10.1136/bcr-2019-231796. PMID: 31796461Free PMC Article

Prognosis

Simbolo M, Silvestris N, Malleo G, Mafficini A, Maggino L, Cocomazzi A, Veghini L, Mombello A, Pezzini F, Sereni E, Martelli FM, Gkountakos A, Ciaparrone C, Piredda ML, Ingravallo G, Paolino G, Nappo F, Rapposelli IG, Frassinetti L, Saragoni L, Lonardi S, Pea A, Paiella S, Fassan M, Brunetti O, Cingarlini S, Salvia R, Milella M, Corbo V, Lawlor RT, Scarpa A, Luchini C
Mod Pathol 2023 Sep;36(9):100251. Epub 2023 Jun 22 doi: 10.1016/j.modpat.2023.100251. PMID: 37355152
Xue Y, Reid MD
Surg Pathol Clin 2020 Sep;13(3):453-467. Epub 2020 Jul 15 doi: 10.1016/j.path.2020.05.005. PMID: 32773194
Hirabayashi K, Zamboni G, Ito H, Ogawa M, Kawaguchi Y, Yamashita T, Nakagohri T, Nakamura N
World J Gastroenterol 2013 Jun 7;19(21):3358-63. doi: 10.3748/wjg.v19.i21.3358. PMID: 23745041Free PMC Article
Chiaravalli AM, Finzi G, Bertolini V, La Rosa S, Capella C
Virchows Arch 2009 Dec;455(6):527-31. Epub 2009 Nov 12 doi: 10.1007/s00428-009-0852-5. PMID: 19908063
Cho YM, Choi J, Lee OJ, Lee HI, Han DJ, Ro JY
Pathol Int 2006 Nov;56(11):702-6. doi: 10.1111/j.1440-1827.2006.02033.x. PMID: 17040295

Clinical prediction guides

Xue Y, Reid MD
Surg Pathol Clin 2020 Sep;13(3):453-467. Epub 2020 Jul 15 doi: 10.1016/j.path.2020.05.005. PMID: 32773194
Hirabayashi K, Zamboni G, Ito H, Ogawa M, Kawaguchi Y, Yamashita T, Nakagohri T, Nakamura N
World J Gastroenterol 2013 Jun 7;19(21):3358-63. doi: 10.3748/wjg.v19.i21.3358. PMID: 23745041Free PMC Article
Chiaravalli AM, Finzi G, Bertolini V, La Rosa S, Capella C
Virchows Arch 2009 Dec;455(6):527-31. Epub 2009 Nov 12 doi: 10.1007/s00428-009-0852-5. PMID: 19908063
Winter JM, Ting AH, Vilardell F, Gallmeier E, Baylin SB, Hruban RH, Kern SE, Iacobuzio-Donahue CA
Clin Cancer Res 2008 Jan 15;14(2):412-8. doi: 10.1158/1078-0432.CCR-07-0487. PMID: 18223216Free PMC Article
Hara H, Suda K
Am J Clin Pathol 2008 Jan;129(1):115-29. doi: 10.1309/PHV2244LC8B0P7TR. PMID: 18089497

Supplemental Content

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