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Malignant Fundus Neoplasm

MedGen UID:
1754723
•Concept ID:
C0864946
•
Neoplastic Process

Definition

A primary or metastatic malignant neoplasm that affects the gastric fundus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Fundus Neoplasm

Professional guidelines

PubMed

Challenges in the diagnosis and management of vitreoretinal lymphoma - Clinical and basic approaches.
Takase H, Arai A, Iwasaki Y, Imai A, Nagao T, Kawagishi M, Ishida T, Mochizuki M
Prog Retin Eye Res 2022 Sep;90:101053. Epub 2022 Feb 21 doi: 10.1016/j.preteyeres.2022.101053. PMID: 35210172
Consensus Recommendations for the Diagnosis of Vitreoretinal Lymphoma.
Carbonell D, Mahajan S, Chee SP, Sobolewska B, Agrawal R, Bülow T, Gupta V, Jones NP, Accorinti M, Agarwal M, Batchelor T, Biswas J, Cimino L, tenDam-van Loon NH, de-la-Torre A, Frenkel S, Pe'er J, Kramer M, Miserocchi E, Mochizuki M, Ness T, Rosenbaum JT, Sen HN, Simion M (VRL patient), Sitter H, Vasconcelos-Santos DV, Habot-Wilner Z, Coupland SE, Pulido JS, Smith J, Thorne JE, Zierhut M; Study Group for Vitreoretinal Lymphoma Diagnostics
Ocul Immunol Inflamm 2021 Apr 3;29(3):507-520. Epub 2021 May 19 doi: 10.1080/09273948.2021.1878233. PMID: 34009095
Circumscribed choroidal hemangioma: An overview of clinical manifestation, diagnosis and management.
Sen M, Honavar SG
Indian J Ophthalmol 2019 Dec;67(12):1965-1973. doi: 10.4103/ijo.IJO_2036_19. PMID: 31755430Free PMC Article

Recent clinical studies

Etiology

Ophthalmic Presentation and Outcomes for Malignant Sinonasal Tumors.
Vahdani K, Rose GE
Ophthalmic Plast Reconstr Surg 2022 Jan-Feb 01;38(1):29-33. doi: 10.1097/IOP.0000000000001972. PMID: 33782330
Genotype-phenotype correlation in von Hippel-Lindau disease.
Reich M, Jaegle S, Neumann-Haefelin E, Klingler JH, Evers C, Daniel M, Bucher F, Ludwig F, Nuessle S, Kopp J, Boehringer D, Reinhard T, Lagrèze WA, Lange C, Agostini H, Lang SJ
Acta Ophthalmol 2021 Dec;99(8):e1492-e1500. Epub 2021 Mar 15 doi: 10.1111/aos.14843. PMID: 33720516
Using risk factors for detection and prognostication of uveal melanoma.
Rishi P, Koundanya VV, Shields CL
Indian J Ophthalmol 2015 Feb;63(2):110-6. doi: 10.4103/0301-4738.154373. PMID: 25827540Free PMC Article
Pigmented and depigmented lesions of the ocular fundus.
Traboulsi EI
Curr Opin Ophthalmol 2012 Sep;23(5):337-43. doi: 10.1097/ICU.0b013e32835622b0. PMID: 22847029
Torpedo maculopathy.
Teitelbaum BA, Hachey DL, Messner LV
J Am Optom Assoc 1997 Jun;68(6):373-6. PMID: 9190137

Diagnosis

Intraocular Tumors: Angiographic Patterns.
Bowen RC, Raval V, Soto H, Singh AD
Asia Pac J Ophthalmol (Phila) 2020 Sep-Oct;9(5):449-460. doi: 10.1097/APO.0000000000000323. PMID: 32960821
MELANOCYTOMA OR JUXTAPAPILLARY MELANOMA?
Baartman BJ, Ahmad B, Srivastava S, Jones S, Singh AD
Retin Cases Brief Rep 2019 Winter;13(1):15-17. doi: 10.1097/ICB.0000000000000520. PMID: 28060135
Choroidal malignant melanoma.
Murphy SF, Mahl CF, Bloom SM
Optom Clin 1993;3(3):63-77. PMID: 8199451
Diffuse infiltrating retinoblastoma.
Bhatnagar R, Vine AK
Ophthalmology 1991 Nov;98(11):1657-61. doi: 10.1016/s0161-6420(91)32072-4. PMID: 1800925
Melanocytoma.
Stone R, Tate HR
Arch Ophthalmol 1975 Jul;93(7):540-1. doi: 10.1001/archopht.1975.01010020556016. PMID: 1138699

Therapy

PET/CT and PET/MRI in ophthalmic oncology (Review).
Kalemaki MS, Karantanas AH, Exarchos D, Detorakis ET, Zoras O, Marias K, Millo C, Bagci U, Pallikaris I, Stratis A, Karatzanis I, Perisinakis K, Koutentakis P, Kontadakis GA, Spandidos DA, Tsatsakis A, Papadakis GZ
Int J Oncol 2020 Feb;56(2):417-429. Epub 2020 Jan 3 doi: 10.3892/ijo.2020.4955. PMID: 31939615Free PMC Article
Circumscribed choroidal hemangioma: An overview of clinical manifestation, diagnosis and management.
Sen M, Honavar SG
Indian J Ophthalmol 2019 Dec;67(12):1965-1973. doi: 10.4103/ijo.IJO_2036_19. PMID: 31755430Free PMC Article
I Can't See.
Leung EH, Stout JT
J Pediatr Ophthalmol Strabismus 2019 Mar 19;56(2):71. doi: 10.3928/01913913-20190212-01. PMID: 30889258
A Rare Cause of Uveitis: Vemurafenib.
Sızmaz S, Görkemli N, Esen E, Demircan N
Turk J Ophthalmol 2018 Dec 27;48(6):323-325. doi: 10.4274/tjo.95914. PMID: 30605942Free PMC Article
Emergency oesophagectomy.
Kerr WF
Thorax 1968 Mar;23(2):204-9. doi: 10.1136/thx.23.2.204. PMID: 5654080Free PMC Article

Prognosis

Genotype-phenotype correlation in von Hippel-Lindau disease.
Reich M, Jaegle S, Neumann-Haefelin E, Klingler JH, Evers C, Daniel M, Bucher F, Ludwig F, Nuessle S, Kopp J, Boehringer D, Reinhard T, Lagrèze WA, Lange C, Agostini H, Lang SJ
Acta Ophthalmol 2021 Dec;99(8):e1492-e1500. Epub 2021 Mar 15 doi: 10.1111/aos.14843. PMID: 33720516
A proteomics based approach for the identification of gastric cancer related markers.
Sheikh IA, Mirza Z, Ali A, Aliev G, Ashraf GM
Curr Pharm Des 2016;22(7):804-11. doi: 10.2174/1381612822666151209151848. PMID: 26648471
Using risk factors for detection and prognostication of uveal melanoma.
Rishi P, Koundanya VV, Shields CL
Indian J Ophthalmol 2015 Feb;63(2):110-6. doi: 10.4103/0301-4738.154373. PMID: 25827540Free PMC Article
Fundus lesions of adenomatous polyposis.
Tiret A, Parc C
Curr Opin Ophthalmol 1999 Jun;10(3):168-72. doi: 10.1097/00055735-199906000-00003. PMID: 10537774
Choroidal malignant melanoma.
Murphy SF, Mahl CF, Bloom SM
Optom Clin 1993;3(3):63-77. PMID: 8199451

Clinical prediction guides

Dissecting transcriptional heterogeneity in primary gastric adenocarcinoma by single cell RNA sequencing.
Zhang M, Hu S, Min M, Ni Y, Lu Z, Sun X, Wu J, Liu B, Ying X, Liu Y
Gut 2021 Mar;70(3):464-475. Epub 2020 Jun 12 doi: 10.1136/gutjnl-2019-320368. PMID: 32532891Free PMC Article
Retinoblastoma, the visible CNS tumor: A review.
Dimaras H, Corson TW
J Neurosci Res 2019 Jan;97(1):29-44. Epub 2018 Jan 3 doi: 10.1002/jnr.24213. PMID: 29314142Free PMC Article
Gastric adenocarcinoma of fundic gland type with signet-ring cell carcinoma component: A case report and review of the literature.
Kai K, Satake M, Tokunaga O
World J Gastroenterol 2018 Jul 14;24(26):2915-2920. doi: 10.3748/wjg.v24.i26.2915. PMID: 30018486Free PMC Article
SELF-PEELING EPIRETINAL MEMBRANE.
Ozgonul C, Besirli CG
Retin Cases Brief Rep 2018 Summer;12(3):196-199. doi: 10.1097/ICB.0000000000000485. PMID: 27930436
DNA methylation markers for diagnosis and prognosis of common cancers.
Hao X, Luo H, Krawczyk M, Wei W, Wang W, Wang J, Flagg K, Hou J, Zhang H, Yi S, Jafari M, Lin D, Chung C, Caughey BA, Li G, Dhar D, Shi W, Zheng L, Hou R, Zhu J, Zhao L, Fu X, Zhang E, Zhang C, Zhu JK, Karin M, Xu RH, Zhang K
Proc Natl Acad Sci U S A 2017 Jul 11;114(28):7414-7419. Epub 2017 Jun 26 doi: 10.1073/pnas.1703577114. PMID: 28652331Free PMC Article

Recent systematic reviews

Pediatric Cataract Surgery Following Treatment for Retinoblastoma: A Case Series and Systematic Review.
Kletke SN, Mallipatna A, Mireskandari K, Gallie BL, Ali A
Am J Ophthalmol 2022 Jul;239:130-141. Epub 2022 Feb 13 doi: 10.1016/j.ajo.2022.02.001. PMID: 35172168
Systematic review of giant gastric lipomas reported since 1980 and report of two new cases in a review of 117110 esophagogastroduodenoscopies.
Cappell MS, Stevens CE, Amin M
World J Gastroenterol 2017 Aug 14;23(30):5619-5633. doi: 10.3748/wjg.v23.i30.5619. PMID: 28852321Free PMC Article
Systematic review with meta-analysis: fundic gland polyps and proton pump inhibitors.
Martin FC, Chenevix-Trench G, Yeomans ND
Aliment Pharmacol Ther 2016 Nov;44(9):915-925. Epub 2016 Sep 15 doi: 10.1111/apt.13800. PMID: 27634363
Use of Proton Pump Inhibitors and Risks of Fundic Gland Polyps and Gastric Cancer: Systematic Review and Meta-analysis.
Tran-Duy A, Spaetgens B, Hoes AW, de Wit NJ, Stehouwer CD
Clin Gastroenterol Hepatol 2016 Dec;14(12):1706-1719.e5. Epub 2016 May 20 doi: 10.1016/j.cgh.2016.05.018. PMID: 27211501
Esophagogastric cancer after bariatric surgery: systematic review of the literature.
Scozzari G, Trapani R, Toppino M, Morino M
Surg Obes Relat Dis 2013 Jan-Feb;9(1):133-42. Epub 2012 Oct 12 doi: 10.1016/j.soard.2012.10.002. PMID: 23265766

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