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Small Hepatocellular Carcinoma

MedGen UID:
1754837
Concept ID:
C5419807
Neoplastic Process
Synonym: Small HCC

Definition

Hepatocellular carcinoma measuring equal to or less than 2 cm in diameter. It includes early hepatocellular carcinoma and small progressed hepatocellular carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSmall Hepatocellular Carcinoma

Professional guidelines

PubMed

Santambrogio R, Barabino M, D'Alessandro V, Iacob G, Opocher E, Gemma M, Zappa MA
Updates Surg 2021 Aug;73(4):1359-1369. Epub 2021 Apr 5 doi: 10.1007/s13304-021-01036-0. PMID: 33821430
Hernandez-Gea V, Turon F, Berzigotti A, Villanueva A
World J Gastroenterol 2013 Feb 28;19(8):1193-9. doi: 10.3748/wjg.v19.i8.1193. PMID: 23482437Free PMC Article
Leoni S, Piscaglia F, Righini R, Bolondi L
Acta Gastroenterol Belg 2006 Apr-Jun;69(2):230-5. PMID: 16929622

Recent clinical studies

Etiology

Li LQ, Su TS, Wu QY, Lin ZT, Liang SX
Clin Oncol (R Coll Radiol) 2023 Oct;35(10):652-664. Epub 2023 Jul 13 doi: 10.1016/j.clon.2023.07.002. PMID: 37541936
Ichikawa S, Goshima S
Magn Reson Med Sci 2023 Apr 1;22(2):157-175. Epub 2023 Feb 1 doi: 10.2463/mrms.rev.2022-0100. PMID: 36725068Free PMC Article
Wang YQ, Wang AJ, Zhang TT, Chen SH
Sci Rep 2022 Sep 20;12(1):15676. doi: 10.1038/s41598-022-19531-8. PMID: 36127436Free PMC Article
Hytiroglou P, Park YN, Krinsky G, Theise ND
Gastroenterol Clin North Am 2007 Dec;36(4):867-87, vii. doi: 10.1016/j.gtc.2007.08.010. PMID: 17996795
Marrero JA
Curr Opin Gastroenterol 2006 May;22(3):248-53. doi: 10.1097/01.mog.0000218961.86182.8c. PMID: 16550039

Diagnosis

Ichikawa S, Goshima S
Magn Reson Med Sci 2023 Apr 1;22(2):157-175. Epub 2023 Feb 1 doi: 10.2463/mrms.rev.2022-0100. PMID: 36725068Free PMC Article
Li Y, Chen J, Weng S, Sun H, Yan C, Xu X, Ye R, Hong J
Clin Radiol 2019 Aug;74(8):653.e1-653.e9. Epub 2019 Jun 11 doi: 10.1016/j.crad.2019.05.009. PMID: 31200932
Hytiroglou P, Park YN, Krinsky G, Theise ND
Gastroenterol Clin North Am 2007 Dec;36(4):867-87, vii. doi: 10.1016/j.gtc.2007.08.010. PMID: 17996795
Leoni S, Piscaglia F, Righini R, Bolondi L
Acta Gastroenterol Belg 2006 Apr-Jun;69(2):230-5. PMID: 16929622
Marrero JA
Curr Opin Gastroenterol 2006 May;22(3):248-53. doi: 10.1097/01.mog.0000218961.86182.8c. PMID: 16550039

Therapy

Li LQ, Su TS, Wu QY, Lin ZT, Liang SX
Clin Oncol (R Coll Radiol) 2023 Oct;35(10):652-664. Epub 2023 Jul 13 doi: 10.1016/j.clon.2023.07.002. PMID: 37541936
Jarnagin WR
Ann Surg Oncol 2010 May;17(5):1226-33. Epub 2010 Apr 20 doi: 10.1245/s10434-010-0978-3. PMID: 20405327Free PMC Article
Yin XY, Lu MD
Expert Rev Gastroenterol Hepatol 2009 Apr;3(2):121-30. doi: 10.1586/egh.09.7. PMID: 19351283
Marrero JA
Curr Opin Gastroenterol 2006 May;22(3):248-53. doi: 10.1097/01.mog.0000218961.86182.8c. PMID: 16550039
Lin SM, Lin DY
Chang Gung Med J 2003 May;26(5):308-14. PMID: 12934846

Prognosis

Wang YQ, Wang AJ, Zhang TT, Chen SH
Sci Rep 2022 Sep 20;12(1):15676. doi: 10.1038/s41598-022-19531-8. PMID: 36127436Free PMC Article
Karadag Soylu N
J Gastrointest Cancer 2020 Dec;51(4):1176-1186. doi: 10.1007/s12029-020-00499-5. PMID: 32844348
Li Y, Chen J, Weng S, Sun H, Yan C, Xu X, Ye R, Hong J
Clin Radiol 2019 Aug;74(8):653.e1-653.e9. Epub 2019 Jun 11 doi: 10.1016/j.crad.2019.05.009. PMID: 31200932
Jiang K, Zhang W, Su M, Liu Y, Zhao X, Wang J, Yao M, Ogbonna J, Dong J, Huang Z
Eur J Surg Oncol 2013 Nov;39(11):1236-42. Epub 2013 Aug 29 doi: 10.1016/j.ejso.2013.08.002. PMID: 23993049
Marrero JA
Curr Opin Gastroenterol 2006 May;22(3):248-53. doi: 10.1097/01.mog.0000218961.86182.8c. PMID: 16550039

Clinical prediction guides

Wu X, Wei M, Chen Y, Peng Z
J Cancer Res Ther 2023 Apr;19(Supplement):S166-S171. doi: 10.4103/jcrt.JCRT_1604_20. PMID: 37147994
Wang YQ, Wang AJ, Zhang TT, Chen SH
Sci Rep 2022 Sep 20;12(1):15676. doi: 10.1038/s41598-022-19531-8. PMID: 36127436Free PMC Article
Santambrogio R, Barabino M, D'Alessandro V, Iacob G, Opocher E, Gemma M, Zappa MA
Updates Surg 2021 Aug;73(4):1359-1369. Epub 2021 Apr 5 doi: 10.1007/s13304-021-01036-0. PMID: 33821430
Kaibori M, Yoshii K, Hasegawa K, Ariizumi S, Kobayashi T, Kamiyama T, Kudo A, Yamaue H, Kokudo N, Yamamoto M
J Hepatobiliary Pancreat Sci 2020 Jun;27(6):331-341. Epub 2020 Feb 27 doi: 10.1002/jhbp.720. PMID: 32012448
Li Y, Chen J, Weng S, Sun H, Yan C, Xu X, Ye R, Hong J
Clin Radiol 2019 Aug;74(8):653.e1-653.e9. Epub 2019 Jun 11 doi: 10.1016/j.crad.2019.05.009. PMID: 31200932

Recent systematic reviews

Shaaban Abdelgalil M, Amer BE, Yasen N, El-Samahy M, Awad AK, Elfakharany B, Saeed O, Abd-ElGawad M
World J Surg Oncol 2024 Feb 7;22(1):47. doi: 10.1186/s12957-023-03292-3. PMID: 38326841Free PMC Article
Wade R, South E, Anwer S, Sharif-Hurst S, Harden M, Fulbright H, Hodgson R, Dias S, Simmonds M, Rowe I, Thornton P, Eastwood A
Health Technol Assess 2023 Dec;27(29):1-172. doi: 10.3310/GK5221. PMID: 38149643Free PMC Article
Li LQ, Su TS, Wu QY, Lin ZT, Liang SX
Clin Oncol (R Coll Radiol) 2023 Oct;35(10):652-664. Epub 2023 Jul 13 doi: 10.1016/j.clon.2023.07.002. PMID: 37541936
Dai XM, Xiang ZQ, Wang Q, Li HJ, Zhu Z
World J Surg Oncol 2022 Sep 19;20(1):299. doi: 10.1186/s12957-022-02770-4. PMID: 36117165Free PMC Article
Jiang K, Zhang W, Su M, Liu Y, Zhao X, Wang J, Yao M, Ogbonna J, Dong J, Huang Z
Eur J Surg Oncol 2013 Nov;39(11):1236-42. Epub 2013 Aug 29 doi: 10.1016/j.ejso.2013.08.002. PMID: 23993049

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