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Laryngeal Neuroendocrine Carcinoma

MedGen UID:
1754876
•Concept ID:
C5420182
•
Neoplastic Process
Synonym: Primary Laryngeal Neuroendocrine Carcinoma

Definition

A rare neuroendocrine carcinoma that arises from the larynx. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLaryngeal Neuroendocrine Carcinoma

Professional guidelines

PubMed

Differential diagnosis of calcitonin-secreting neuroendocrine carcinoma of the foregut by pentagastrin stimulation.
Machens A, Haedecke J, Holzhausen HJ, Thomusch O, Schneyer U, Dralle H
Langenbecks Arch Surg 2000 Oct;385(6):398-401. doi: 10.1007/s004230000169. PMID: 11127524

Recent clinical studies

Etiology

Application of INSM1 in Diagnosis and Grading of Laryngeal Neuroendocrine Carcinoma.
Yuan C, Jiao F, Zhai C, Zhang J, Wang S, Zhu L
Laryngoscope 2021 Oct;131(10):E2662-E2668. Epub 2021 Apr 13 doi: 10.1002/lary.29554. PMID: 33847383
Is human papillomavirus involved in laryngeal neuroendocrine carcinoma?
Halmos GB, van der Laan TP, van Hemel BM, Dikkers FG, Slagter-Menkema L, van der Laan BF, Schuuring E
Eur Arch Otorhinolaryngol 2013 Feb;270(2):719-25. Epub 2012 Jun 15 doi: 10.1007/s00405-012-2075-7. PMID: 22699626Free PMC Article
Differential diagnosis of calcitonin-secreting neuroendocrine carcinoma of the foregut by pentagastrin stimulation.
Machens A, Haedecke J, Holzhausen HJ, Thomusch O, Schneyer U, Dralle H
Langenbecks Arch Surg 2000 Oct;385(6):398-401. doi: 10.1007/s004230000169. PMID: 11127524

Diagnosis

Application of INSM1 in Diagnosis and Grading of Laryngeal Neuroendocrine Carcinoma.
Yuan C, Jiao F, Zhai C, Zhang J, Wang S, Zhu L
Laryngoscope 2021 Oct;131(10):E2662-E2668. Epub 2021 Apr 13 doi: 10.1002/lary.29554. PMID: 33847383
Laryngeal Neuroendocrine Carcinoma: A Population-Based Analysis of Incidence and Survival.
Ghosh R, Dutta R, Dubal PM, Park RC, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2015 Dec;153(6):966-72. Epub 2015 Jul 16 doi: 10.1177/0194599815594386. PMID: 26183520
Primary moderately differentiated neuroendocrine carcinoma (atypical carcinoid) of the larynx: A case report with immunohistochemical and molecular study.
Giordano G, Corcione L, Giordano D, D'Adda T, Gnetti L, Ferri T
Auris Nasus Larynx 2009 Apr;36(2):228-31. Epub 2008 Jul 9 doi: 10.1016/j.anl.2008.05.002. PMID: 18617341
Atypical carcinoid (neuroendocrine carcinoma) of the gingiva: counterpart of a laryngeal tumor.
Abiko Y, Ogawa I, Hattori Y, Kusano K, Nishimura M, Ohuchi T, Abe U, Shibata T, Matsuda S, Takata T, Kaku T
Pathol Int 2004 Feb;54(2):97-100. doi: 10.1111/j.1440-1827.2004.01598.x. PMID: 14720139
Differential diagnosis of calcitonin-secreting neuroendocrine carcinoma of the foregut by pentagastrin stimulation.
Machens A, Haedecke J, Holzhausen HJ, Thomusch O, Schneyer U, Dralle H
Langenbecks Arch Surg 2000 Oct;385(6):398-401. doi: 10.1007/s004230000169. PMID: 11127524

Prognosis

Hypopharyngeal squamous cell carcinoma and laryngeal neuroendocrine carcinoma colliding in the aryepiglottic fold: a case report.
Marangoni R, Mauramati S, Bertino G, Occhini A, Benazzo M, Morbini P
Tumori 2017 Nov 15;103(Suppl. 1):e1-e4. doi: 10.5301/tj.5000630. PMID: 28430347
Laryngeal Neuroendocrine Carcinoma: A Population-Based Analysis of Incidence and Survival.
Ghosh R, Dutta R, Dubal PM, Park RC, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2015 Dec;153(6):966-72. Epub 2015 Jul 16 doi: 10.1177/0194599815594386. PMID: 26183520
Is human papillomavirus involved in laryngeal neuroendocrine carcinoma?
Halmos GB, van der Laan TP, van Hemel BM, Dikkers FG, Slagter-Menkema L, van der Laan BF, Schuuring E
Eur Arch Otorhinolaryngol 2013 Feb;270(2):719-25. Epub 2012 Jun 15 doi: 10.1007/s00405-012-2075-7. PMID: 22699626Free PMC Article
Large cell neuroendocrine carcinoma of the larynx: definition of an entity.
Lewis JS Jr, Spence DC, Chiosea S, Barnes EL Jr, Brandwein-Gensler M, El-Mofty SK
Head Neck Pathol 2010 Sep;4(3):198-207. Epub 2010 Jun 30 doi: 10.1007/s12105-010-0188-0. PMID: 20589486Free PMC Article

Clinical prediction guides

Application of INSM1 in Diagnosis and Grading of Laryngeal Neuroendocrine Carcinoma.
Yuan C, Jiao F, Zhai C, Zhang J, Wang S, Zhu L
Laryngoscope 2021 Oct;131(10):E2662-E2668. Epub 2021 Apr 13 doi: 10.1002/lary.29554. PMID: 33847383
Atypical carcinoid (neuroendocrine carcinoma) of the gingiva: counterpart of a laryngeal tumor.
Abiko Y, Ogawa I, Hattori Y, Kusano K, Nishimura M, Ohuchi T, Abe U, Shibata T, Matsuda S, Takata T, Kaku T
Pathol Int 2004 Feb;54(2):97-100. doi: 10.1111/j.1440-1827.2004.01598.x. PMID: 14720139

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