Metastatic Anal Carcinoma

MedGen UID:: 1755103
•Concept ID:: C5401417
•: Neoplastic Process

Definition

Anal carcinoma that has spread from its primary site to another anatomic site. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMetastatic Anal Carcinoma

Disorder by Site
- Disorder of gastrointestinal tract
  - Anus disorder
    - Anus neoplasm
      - Anus cancer
        Anal carcinoma
        Metastatic Anal Carcinoma
        Advanced Anal Carcinoma
        Advanced Anal Canal Squamous Cell Carcinoma
        Locally Advanced Anal Carcinoma
        Metastatic Anal Canal Carcinoma
        Metastatic Anal Canal Squamous Cell Carcinoma
        Metastatic Anal Squamous Cell Carcinoma

Professional guidelines

PubMed

Anal Carcinoma, Version 2.2023, NCCN Clinical Practice Guidelines in Oncology.

Benson AB, Venook AP, Al-Hawary MM, Azad N, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Garrido-Laguna I, Grem JL, Hecht JR, Hoffe S, Hubbard J, Hunt S, Hussan H, Jeck W, Johung KL, Joseph N, Kirilcuk N, Krishnamurthi S, Maratt J, Messersmith WA, Meyerhardt J, Miller ED, Mulcahy MF, Nurkin S, Overman MJ, Parikh A, Patel H, Pedersen K, Saltz L, Schneider C, Shibata D, Skibber JM, Sofocleous CT, Stotsky-Himelfarb E, Tavakkoli A, Willett CG, Williams G, Algieri F, Gurski L, Stehman K
J Natl Compr Canc Netw 2023 Jun;21(6):653-677. doi: 10.6004/jnccn.2023.0030. PMID: 37308125

Platinum-Fluoropyrimidine and Paclitaxel-Based Chemotherapy in the Treatment of Advanced Anal Cancer Patients.

Sclafani F, Morano F, Cunningham D, Baratelli C, Kalaitzaki E, Watkins D, Starling N, Chau I, Rao S
Oncologist 2017 Apr;22(4):402-408. Epub 2017 Feb 16 doi: 10.1634/theoncologist.2016-0241. PMID: 28209745 Free PMC Article

Treatment options in metastatic squamous cell carcinoma of the anal canal.

Eng C, Pathak P
Curr Treat Options Oncol 2008 Dec;9(4-6):400-7. Epub 2009 May 29 doi: 10.1007/s11864-009-0103-7. PMID: 19479383

See all (3)

Recent clinical studies

Etiology

Relapsed refractory metastatic squamous cell cancer of anal canal in a patient with retroviral infection responding to cetuximab.

Lerner J, Michel M, Dasanu CA
J Oncol Pharm Pract 2020 Jun;26(4):1025-1028. Epub 2019 Nov 4 doi: 10.1177/1078155219884605. PMID: 31684821

Does gap-free intensity modulated chemoradiation therapy provide a greater clinical benefit than 3D conformal chemoradiation in patients with anal cancer?

Dewas CV, Maingon P, Dalban C, Petitfils A, Peignaux K, Truc G, Martin E, Khoury C, Dewas S, Créhange G
Radiat Oncol 2012 Nov 29;7:201. doi: 10.1186/1748-717X-7-201. PMID: 23190693 Free PMC Article

See all (2)

Diagnosis

Combined multimodal approach to the treatment of metastatic anal carcinoma: report of a case and review of the literature.

Tokar M, Bobilev D, Zalmanov S, Geffen DB, Walfisch S
Onkologie 2006 Feb;29(1-2):30-2. doi: 10.1159/000089798. PMID: 16514253

See all (1)

Therapy

Relapsed refractory metastatic squamous cell cancer of anal canal in a patient with retroviral infection responding to cetuximab.

Lerner J, Michel M, Dasanu CA
J Oncol Pharm Pract 2020 Jun;26(4):1025-1028. Epub 2019 Nov 4 doi: 10.1177/1078155219884605. PMID: 31684821

Platinum-Fluoropyrimidine and Paclitaxel-Based Chemotherapy in the Treatment of Advanced Anal Cancer Patients.

Does gap-free intensity modulated chemoradiation therapy provide a greater clinical benefit than 3D conformal chemoradiation in patients with anal cancer?

Dewas CV, Maingon P, Dalban C, Petitfils A, Peignaux K, Truc G, Martin E, Khoury C, Dewas S, Créhange G
Radiat Oncol 2012 Nov 29;7:201. doi: 10.1186/1748-717X-7-201. PMID: 23190693 Free PMC Article

Treatment options in metastatic squamous cell carcinoma of the anal canal.

Eng C, Pathak P
Curr Treat Options Oncol 2008 Dec;9(4-6):400-7. Epub 2009 May 29 doi: 10.1007/s11864-009-0103-7. PMID: 19479383

Combined multimodal approach to the treatment of metastatic anal carcinoma: report of a case and review of the literature.

Tokar M, Bobilev D, Zalmanov S, Geffen DB, Walfisch S
Onkologie 2006 Feb;29(1-2):30-2. doi: 10.1159/000089798. PMID: 16514253

See all (6)

Prognosis

Relapsed refractory metastatic squamous cell cancer of anal canal in a patient with retroviral infection responding to cetuximab.

Lerner J, Michel M, Dasanu CA
J Oncol Pharm Pract 2020 Jun;26(4):1025-1028. Epub 2019 Nov 4 doi: 10.1177/1078155219884605. PMID: 31684821

Platinum-Fluoropyrimidine and Paclitaxel-Based Chemotherapy in the Treatment of Advanced Anal Cancer Patients.

Does gap-free intensity modulated chemoradiation therapy provide a greater clinical benefit than 3D conformal chemoradiation in patients with anal cancer?

Dewas CV, Maingon P, Dalban C, Petitfils A, Peignaux K, Truc G, Martin E, Khoury C, Dewas S, Créhange G
Radiat Oncol 2012 Nov 29;7:201. doi: 10.1186/1748-717X-7-201. PMID: 23190693 Free PMC Article

Treatment options in metastatic squamous cell carcinoma of the anal canal.

Eng C, Pathak P
Curr Treat Options Oncol 2008 Dec;9(4-6):400-7. Epub 2009 May 29 doi: 10.1007/s11864-009-0103-7. PMID: 19479383

See all (4)