U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Malignant Inner Ear Neoplasm

MedGen UID:
1757413
•Concept ID:
C2837942
•
Neoplastic Process

Definition

A malignant neoplasm that affects the inner ear. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Inner Ear Neoplasm

Professional guidelines

PubMed

Cisplatin in Ovarian Cancer Treatment-Known Limitations in Therapy Force New Solutions.
Zoń A, Bednarek I
Int J Mol Sci 2023 Apr 20;24(8) doi: 10.3390/ijms24087585. PMID: 37108749Free PMC Article
The Future of Vestibular Schwannoma Management.
Moore LS, Stankovic KM
Otolaryngol Clin North Am 2023 Jun;56(3):611-622. Epub 2023 Apr 3 doi: 10.1016/j.otc.2023.02.018. PMID: 37019772
Prenatal diagnosis of vermian cyst: a new type of posterior fossa cyst.
Chanclud J, Valence S, Perre SV, Guilbaud L, Moutard ML, Jouannic JM, Ducou Le Pointe H, Blondiaux E, Garel C
Pediatr Radiol 2023 Mar;53(3):461-469. Epub 2022 Oct 24 doi: 10.1007/s00247-022-05531-3. PMID: 36274068

Recent clinical studies

Etiology

von Hippel-Lindau disease: Updated guideline for diagnosis and surveillance.
Louise M Binderup M, Smerdel M, Borgwadt L, Beck Nielsen SS, Madsen MG, Møller HU, Kiilgaard JF, Friis-Hansen L, Harbud V, Cortnum S, Owen H, Gimsing S, Friis Juhl HA, Munthe S, Geilswijk M, Rasmussen ÅK, Møldrup U, Graumann O, Donskov F, Grønbæk H, Stausbøl-Grøn B, Schaffalitzky de Muckadell O, Knigge U, Dam G, Wadt KA, Bøgeskov L, Bagi P, Lund L, Stochholm K, Ousager LB, Sunde L
Eur J Med Genet 2022 Aug;65(8):104538. Epub 2022 Jun 13 doi: 10.1016/j.ejmg.2022.104538. PMID: 35709961
SOX10: 20 years of phenotypic plurality and current understanding of its developmental function.
Pingault V, Zerad L, Bertani-Torres W, Bondurand N
J Med Genet 2022 Feb;59(2):105-114. Epub 2021 Oct 19 doi: 10.1136/jmedgenet-2021-108105. PMID: 34667088Free PMC Article
Aminoglycoside- and Cisplatin-Induced Ototoxicity: Mechanisms and Otoprotective Strategies.
Kros CJ, Steyger PS
Cold Spring Harb Perspect Med 2019 Nov 1;9(11) doi: 10.1101/cshperspect.a033548. PMID: 30559254Free PMC Article
Primary inner ear schwannomas: a case series and systematic review of the literature.
Van Abel KM, Carlson ML, Link MJ, Neff BA, Beatty CW, Lohse CM, Eckel LJ, Lane JI, Driscoll CL
Laryngoscope 2013 Aug;123(8):1957-66. Epub 2013 Jan 18 doi: 10.1002/lary.23928. PMID: 23335152
Radiotherapy-induced ear toxicity.
Jereczek-Fossa BA, Zarowski A, Milani F, Orecchia R
Cancer Treat Rev 2003 Oct;29(5):417-30. doi: 10.1016/s0305-7372(03)00066-5. PMID: 12972360

Diagnosis

The Vestibulocochlear Nerve: Anatomy and Pathology.
Corrêa DG, Hygino da Cruz LC Jr, Freddi TAL
Semin Ultrasound CT MR 2023 Apr;44(2):81-94. Epub 2023 Mar 22 doi: 10.1053/j.sult.2023.03.007. PMID: 37055143
Tumors of the temporal bone.
Chovanec M, Fík Z
Cas Lek Cesk 2019 Winter;158(6):248-252. PMID: 31931585
Intralabyrinthine schwannomas.
Frisch CD, Eckel LJ, Lane JI, Neff BA
Otolaryngol Clin North Am 2015 Jun;48(3):423-41. Epub 2015 Apr 9 doi: 10.1016/j.otc.2015.02.004. PMID: 25863567
Imaging diagnostics: congenital malformations and acquired lesions of the inner ear.
Pont E, Mazón M, Montesinos P, Sánchez MÁ, Más-Estellés F
Acta Otorrinolaringol Esp 2015 Jul-Aug;66(4):224-33. Epub 2014 Oct 12 doi: 10.1016/j.otorri.2014.07.002. PMID: 25312404
Primary inner ear schwannomas: a case series and systematic review of the literature.
Van Abel KM, Carlson ML, Link MJ, Neff BA, Beatty CW, Lohse CM, Eckel LJ, Lane JI, Driscoll CL
Laryngoscope 2013 Aug;123(8):1957-66. Epub 2013 Jan 18 doi: 10.1002/lary.23928. PMID: 23335152

Therapy

Cisplatin in Ovarian Cancer Treatment-Known Limitations in Therapy Force New Solutions.
Zoń A, Bednarek I
Int J Mol Sci 2023 Apr 20;24(8) doi: 10.3390/ijms24087585. PMID: 37108749Free PMC Article
In vivo delivery of CRISPR-Cas9 genome editing components for therapeutic applications.
Huang K, Zapata D, Tang Y, Teng Y, Li Y
Biomaterials 2022 Dec;291:121876. Epub 2022 Oct 28 doi: 10.1016/j.biomaterials.2022.121876. PMID: 36334354Free PMC Article
Aminoglycoside- and Cisplatin-Induced Ototoxicity: Mechanisms and Otoprotective Strategies.
Kros CJ, Steyger PS
Cold Spring Harb Perspect Med 2019 Nov 1;9(11) doi: 10.1101/cshperspect.a033548. PMID: 30559254Free PMC Article
Irradiated ears in nasopharyngeal carcinoma survivors: A review.
Young YH
Laryngoscope 2019 Mar;129(3):637-642. Epub 2018 Sep 8 doi: 10.1002/lary.27303. PMID: 30194730
Radiation therapy and hearing loss.
Bhandare N, Jackson A, Eisbruch A, Pan CC, Flickinger JC, Antonelli P, Mendenhall WM
Int J Radiat Oncol Biol Phys 2010 Mar 1;76(3 Suppl):S50-7. doi: 10.1016/j.ijrobp.2009.04.096. PMID: 20171518Free PMC Article

Prognosis

Data Set for the Reporting of Ear and Temporal Bone Tumors: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting.
Gupta R, Sandison A, Wenig BM, Thompson LDR
Arch Pathol Lab Med 2019 May;143(5):593-602. Epub 2018 Nov 30 doi: 10.5858/arpa.2018-0415-SA. PMID: 30500288
Growth rate of vestibular schwannoma.
Paldor I, Chen AS, Kaye AH
J Clin Neurosci 2016 Oct;32:1-8. Epub 2016 Jul 20 doi: 10.1016/j.jocn.2016.05.003. PMID: 27450283
Primary inner ear schwannomas: a case series and systematic review of the literature.
Van Abel KM, Carlson ML, Link MJ, Neff BA, Beatty CW, Lohse CM, Eckel LJ, Lane JI, Driscoll CL
Laryngoscope 2013 Aug;123(8):1957-66. Epub 2013 Jan 18 doi: 10.1002/lary.23928. PMID: 23335152
Radiation effects on the auditory and vestibular systems.
Bhandare N, Mendenhall WM, Antonelli PJ
Otolaryngol Clin North Am 2009 Aug;42(4):623-34. doi: 10.1016/j.otc.2009.04.002. PMID: 19751868
Radiotherapy-induced ear toxicity.
Jereczek-Fossa BA, Zarowski A, Milani F, Orecchia R
Cancer Treat Rev 2003 Oct;29(5):417-30. doi: 10.1016/s0305-7372(03)00066-5. PMID: 12972360

Clinical prediction guides

Burden of serious harms from diagnostic error in the USA.
Newman-Toker DE, Nassery N, Schaffer AC, Yu-Moe CW, Clemens GD, Wang Z, Zhu Y, Saber Tehrani AS, Fanai M, Hassoon A, Siegal D
BMJ Qual Saf 2024 Jan 19;33(2):109-120. doi: 10.1136/bmjqs-2021-014130. PMID: 37460118Free PMC Article
Cisplatin in Ovarian Cancer Treatment-Known Limitations in Therapy Force New Solutions.
Zoń A, Bednarek I
Int J Mol Sci 2023 Apr 20;24(8) doi: 10.3390/ijms24087585. PMID: 37108749Free PMC Article
SOX10: 20 years of phenotypic plurality and current understanding of its developmental function.
Pingault V, Zerad L, Bertani-Torres W, Bondurand N
J Med Genet 2022 Feb;59(2):105-114. Epub 2021 Oct 19 doi: 10.1136/jmedgenet-2021-108105. PMID: 34667088Free PMC Article
Primary inner ear schwannomas: a case series and systematic review of the literature.
Van Abel KM, Carlson ML, Link MJ, Neff BA, Beatty CW, Lohse CM, Eckel LJ, Lane JI, Driscoll CL
Laryngoscope 2013 Aug;123(8):1957-66. Epub 2013 Jan 18 doi: 10.1002/lary.23928. PMID: 23335152
von Hippel-Lindau disease.
Singh AD, Shields CL, Shields JA
Surv Ophthalmol 2001 Sep-Oct;46(2):117-42. doi: 10.1016/s0039-6257(01)00245-4. PMID: 11578646

Recent systematic reviews

Pre-habilitation with intratympanic gentamicin in vestibular schwannomas: a systematic review.
Potdar T, Kontorinis G
J Laryngol Otol 2023 Sep;137(9):985-991. Epub 2023 Apr 26 doi: 10.1017/S0022215123000725. PMID: 37185086
Systematic Review of Endolymphatic Sac Tumor Treatment and Outcomes.
Tang JD, Grady AJ, Nickel CJ, Ryan LE, Malone A, Canvasser L, Boyev KP
Otolaryngol Head Neck Surg 2023 Mar;168(3):282-290. Epub 2023 Jan 27 doi: 10.1177/01945998221108313. PMID: 35763364
Symptoms and clinical features in patients affected by endolymphatic sac tumor: a systematic review and meta-analysis.
Gioacchini FM, Kaleci S, Chiarella G, Viola P, Pisani D, Scarpa A, Tulli M, Pace A, Iannella G, Re M
Eur Arch Otorhinolaryngol 2022 Nov;279(11):5081-5088. Epub 2022 Jun 15 doi: 10.1007/s00405-022-07469-6. PMID: 35704074
Indications and contraindications of auditory brainstem implants: systematic review and illustrative cases.
Merkus P, Di Lella F, Di Trapani G, Pasanisi E, Beltrame MA, Zanetti D, Negri M, Sanna M
Eur Arch Otorhinolaryngol 2014 Jan;271(1):3-13. Epub 2013 Feb 13 doi: 10.1007/s00405-013-2378-3. PMID: 23404468
Primary inner ear schwannomas: a case series and systematic review of the literature.
Van Abel KM, Carlson ML, Link MJ, Neff BA, Beatty CW, Lohse CM, Eckel LJ, Lane JI, Driscoll CL
Laryngoscope 2013 Aug;123(8):1957-66. Epub 2013 Jan 18 doi: 10.1002/lary.23928. PMID: 23335152

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...