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Skin Soft Tissue Neoplasm

MedGen UID:
1764505
•Concept ID:
C5418298
•
Neoplastic Process

Definition

A mesenchymal neoplasm that arises from the skin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin Soft Tissue Neoplasm

Professional guidelines

PubMed

ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT/IGRT.
Damico N, Meyer J, Das P, Murphy J, Miller E, Koontz B, Hall W, McBride M, Pereira G, Catalano P, Chakravarthy AB, O'Dwyer PJ, Dorth J
Pract Radiat Oncol 2022 Jul-Aug;12(4):335-347. doi: 10.1016/j.prro.2022.01.015. PMID: 35717050
Management of Skin Sarcomas.
Messina V, Cope B, Keung EZ, Fiore M
Surg Oncol Clin N Am 2022 Jul;31(3):511-525. Epub 2022 May 31 doi: 10.1016/j.soc.2022.03.010. PMID: 35715147
Radiation-Induced Skin Fibrosis: Pathogenesis, Current Treatment Options, and Emerging Therapeutics.
Borrelli MR, Shen AH, Lee GK, Momeni A, Longaker MT, Wan DC
Ann Plast Surg 2019 Oct;83(4S Suppl 1):S59-S64. doi: 10.1097/SAP.0000000000002098. PMID: 31513068Free PMC Article

Recent clinical studies

Etiology

Myxoinflammatory Fibroblastic Sarcoma.
Wu H, Laskin WB
Surg Pathol Clin 2024 Mar;17(1):83-96. Epub 2023 Aug 8 doi: 10.1016/j.path.2023.07.003. PMID: 38278610
Hypofractionated, 3-week, preoperative radiotherapy for patients with soft tissue sarcomas (HYPORT-STS): a single-centre, open-label, single-arm, phase 2 trial.
Guadagnolo BA, Bassett RL, Mitra D, Farooqi A, Hempel C, Dorber C, Willis T, Wang WL, Ratan R, Somaiah N, Benjamin RS, Torres KE, Hunt KK, Scally CP, Keung EZ, Satcher RL, Bird JE, Lin PP, Moon BS, Lewis VO, Roland CL, Bishop AJ
Lancet Oncol 2022 Dec;23(12):1547-1557. Epub 2022 Nov 4 doi: 10.1016/S1470-2045(22)00638-6. PMID: 36343656Free PMC Article
Diagnosis and Management of Subcutaneous Soft Tissue Sarcoma.
Endo M, Setsu N, Fujiwara T, Ishii T, Nakagawa M, Yahiro K, Kimura A, Shimada E, Nakashima Y, Matsumoto Y
Curr Treat Options Oncol 2019 May 25;20(7):54. doi: 10.1007/s11864-019-0656-z. PMID: 31129726
Cutaneous sarcomas.
Kohlmeyer J, Steimle-Grauer SA, Hein R
J Dtsch Dermatol Ges 2017 Jun;15(6):630-648. doi: 10.1111/ddg.13249. PMID: 28591457
Kutane Sarkome.
Kohlmeyer J, Steimle-Grauer SA, Hein R
J Dtsch Dermatol Ges 2017 Jun;15(6):630-649. doi: 10.1111/ddg.13249_g. PMID: 28591446

Diagnosis

Myxoinflammatory Fibroblastic Sarcoma.
Wu H, Laskin WB
Surg Pathol Clin 2024 Mar;17(1):83-96. Epub 2023 Aug 8 doi: 10.1016/j.path.2023.07.003. PMID: 38278610
Fibroblastic and Myofibroblastic Soft-Tissue Tumors: Imaging Spectrum and Radiologic-Pathologic Correlation.
Haseli S, Mansoori B, Christensen D, Abadi A, Pooyan A, Shomal Zadeh F, Mau B, Khalili N, Murphey M, Chalian M
Radiographics 2023 Aug;43(8):e230005. doi: 10.1148/rg.230005. PMID: 37440448
Basic Knowledge in Soft Tissue Sarcoma.
Bourcier K, Le Cesne A, Tselikas L, Adam J, Mir O, Honore C, de Baere T
Cardiovasc Intervent Radiol 2019 Sep;42(9):1255-1261. Epub 2019 Jun 24 doi: 10.1007/s00270-019-02259-w. PMID: 31236647
Hamartomas of skin and soft tissue.
Tjarks BJ, Gardner JM, Riddle ND
Semin Diagn Pathol 2019 Jan;36(1):48-61. Epub 2018 Dec 11 doi: 10.1053/j.semdp.2018.12.001. PMID: 30573326
Tumors of the hand.
Mavrogenis AF, Panagopoulos GN, Angelini A, Lesenský J, Vottis C, Megaloikonomos PD, Kokkalis ZT, Kontogeorgakos V, Ruggieri P, Papagelopoulos PJ
Eur J Orthop Surg Traumatol 2017 Aug;27(6):747-762. Epub 2017 Jun 5 doi: 10.1007/s00590-017-1984-y. PMID: 28585186

Therapy

Hypofractionated, 3-week, preoperative radiotherapy for patients with soft tissue sarcomas (HYPORT-STS): a single-centre, open-label, single-arm, phase 2 trial.
Guadagnolo BA, Bassett RL, Mitra D, Farooqi A, Hempel C, Dorber C, Willis T, Wang WL, Ratan R, Somaiah N, Benjamin RS, Torres KE, Hunt KK, Scally CP, Keung EZ, Satcher RL, Bird JE, Lin PP, Moon BS, Lewis VO, Roland CL, Bishop AJ
Lancet Oncol 2022 Dec;23(12):1547-1557. Epub 2022 Nov 4 doi: 10.1016/S1470-2045(22)00638-6. PMID: 36343656Free PMC Article
ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT/IGRT.
Damico N, Meyer J, Das P, Murphy J, Miller E, Koontz B, Hall W, McBride M, Pereira G, Catalano P, Chakravarthy AB, O'Dwyer PJ, Dorth J
Pract Radiat Oncol 2022 Jul-Aug;12(4):335-347. doi: 10.1016/j.prro.2022.01.015. PMID: 35717050
SKIN AND SUBCUTANEOUS ADIPOSE TISSUE DAMAGE AFTER RADIATION THERAPY IN BREAST CANCER PATIENTS.
Bazyka DA, Litvinenko OO, Bugaytsov SG, Shakhrai GF
Probl Radiac Med Radiobiol 2021 Dec;26:18-35. doi: 10.33145/2304-8336-2021-26-18-35. PMID: 34965541
Dermatofibrosarcoma Protuberans.
Allen A, Ahn C, Sangüeza OP
Dermatol Clin 2019 Oct;37(4):483-488. doi: 10.1016/j.det.2019.05.006. PMID: 31466588
Phase II trial of weekly paclitaxel for unresectable angiosarcoma: the ANGIOTAX Study.
Penel N, Bui BN, Bay JO, Cupissol D, Ray-Coquard I, Piperno-Neumann S, Kerbrat P, Fournier C, Taieb S, Jimenez M, Isambert N, Peyrade F, Chevreau C, Bompas E, Brain EG, Blay JY
J Clin Oncol 2008 Nov 10;26(32):5269-74. Epub 2008 Sep 22 doi: 10.1200/JCO.2008.17.3146. PMID: 18809609

Prognosis

Fibroblastic and Myofibroblastic Soft-Tissue Tumors: Imaging Spectrum and Radiologic-Pathologic Correlation.
Haseli S, Mansoori B, Christensen D, Abadi A, Pooyan A, Shomal Zadeh F, Mau B, Khalili N, Murphey M, Chalian M
Radiographics 2023 Aug;43(8):e230005. doi: 10.1148/rg.230005. PMID: 37440448
Ultrasonography of Pediatric Superficial Soft Tissue Tumors and Tumor-Like Lesions.
Kim HW, Yoo SY, Oh S, Jeon TY, Kim JH
Korean J Radiol 2020 Mar;21(3):341-355. doi: 10.3348/kjr.2019.0343. PMID: 32090527Free PMC Article
Basic Knowledge in Soft Tissue Sarcoma.
Bourcier K, Le Cesne A, Tselikas L, Adam J, Mir O, Honore C, de Baere T
Cardiovasc Intervent Radiol 2019 Sep;42(9):1255-1261. Epub 2019 Jun 24 doi: 10.1007/s00270-019-02259-w. PMID: 31236647
Cutaneous sarcomas.
Kohlmeyer J, Steimle-Grauer SA, Hein R
J Dtsch Dermatol Ges 2017 Jun;15(6):630-648. doi: 10.1111/ddg.13249. PMID: 28591457
Kutane Sarkome.
Kohlmeyer J, Steimle-Grauer SA, Hein R
J Dtsch Dermatol Ges 2017 Jun;15(6):630-649. doi: 10.1111/ddg.13249_g. PMID: 28591446

Clinical prediction guides

Fibroblastic and Myofibroblastic Soft-Tissue Tumors: Imaging Spectrum and Radiologic-Pathologic Correlation.
Haseli S, Mansoori B, Christensen D, Abadi A, Pooyan A, Shomal Zadeh F, Mau B, Khalili N, Murphey M, Chalian M
Radiographics 2023 Aug;43(8):e230005. doi: 10.1148/rg.230005. PMID: 37440448
Clinical, histopathological and molecular features of dedifferentiated melanomas: An EORTC Melanoma Group Retrospective Analysis.
Hench J, Mihic-Probst D, Agaimy A, Frank S, Meyer P, Hultschig C, Simi S, Alos L, Balamurugan T, Blokx W, Bosisio F, Cappellesso R, Griewank K, Hadaschik E, van Kempen LC, Kempf W, Lentini M, Mazzucchelli L, Rinaldi G, Rutkowski P, Schadendorf D, Schilling B, Szumera-Cieckiewicz A, van den Oord J, Mandalà M, Massi D; EORTC Melanoma Group
Eur J Cancer 2023 Jul;187:7-14. Epub 2023 Apr 2 doi: 10.1016/j.ejca.2023.03.032. PMID: 37098294
Soft-tissue reconstruction after soft-tissue sarcoma resection: the clinical outcomes of 24 patients.
Hasegawa H, Tsukamoto S, Honoki K, Shimizu T, Ferra L, Errani C, Sioutis S, Mavrogenis AF, Tanaka Y
Eur J Orthop Surg Traumatol 2022 Jan;32(1):1-10. Epub 2021 Feb 20 doi: 10.1007/s00590-021-02901-9. PMID: 33608754
Treatment of a first patient with FLASH-radiotherapy.
Bourhis J, Sozzi WJ, Jorge PG, Gaide O, Bailat C, Duclos F, Patin D, Ozsahin M, Bochud F, Germond JF, Moeckli R, Vozenin MC
Radiother Oncol 2019 Oct;139:18-22. Epub 2019 Jul 11 doi: 10.1016/j.radonc.2019.06.019. PMID: 31303340
Cutaneous myofibroma.
Smith KJ, Skelton HG, Barrett TL, Lupton GP, Graham JH
Mod Pathol 1989 Nov;2(6):603-9. PMID: 2587567

Recent systematic reviews

Dermatofibrosarcoma protuberans of the scalp: Surgical management in a multicentric series of 11 cases and systematic review of the literature.
Kuhlmann C, Ehrl D, Taha S, Wachtel N, Schmid A, Bronsert P, Zeller J, Giunta RE, Eisenhardt SU, Braig D
Surgery 2023 Jun;173(6):1463-1475. Epub 2023 Apr 1 doi: 10.1016/j.surg.2023.02.026. PMID: 37012145
Skin sequelae in patients with infantile hemangioma: a systematic review.
Li W, Kang J, Bai S, Yuan L, Liu J, Bi Y, Sun J, He Y
Eur J Pediatr 2023 Feb;182(2):479-488. Epub 2022 Nov 24 doi: 10.1007/s00431-022-04688-1. PMID: 36434402
Extramedullary disease in multiple myeloma: a systematic literature review.
Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675Free PMC Article
Systemic antibiotics for treating malignant wounds.
Ramasubbu DA, Smith V, Hayden F, Cronin P
Cochrane Database Syst Rev 2017 Aug 24;8(8):CD011609. doi: 10.1002/14651858.CD011609.pub2. PMID: 28837757Free PMC Article
Laser and light-based therapy for cutaneous and soft-tissue metastases of malignant melanoma: a systematic review.
Austin E, Mamalis A, Ho D, Jagdeo J
Arch Dermatol Res 2017 May;309(4):229-242. Epub 2017 Mar 17 doi: 10.1007/s00403-017-1720-9. PMID: 28314913

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