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Unresectable Large Cell Neuroendocrine Carcinoma

MedGen UID:
1766894
Concept ID:
C5419871
Neoplastic Process

Definition

Large cell neuroendocrine carcinoma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Large Cell Neuroendocrine Carcinoma

Professional guidelines

PubMed

Sugawara T, Rodriguez Franco S, Franklin O, Kirsch MJ, Colborn KL, Del Chiaro M, Schulick RD
J Am Coll Surg 2023 Sep 1;237(3):515-524. Epub 2023 May 5 doi: 10.1097/XCS.0000000000000735. PMID: 37146214
Wolin EM
Chest 2017 May;151(5):1141-1146. Epub 2016 Jun 29 doi: 10.1016/j.chest.2016.06.018. PMID: 27373769
Mackley HB, Videtic GM
Oncology (Williston Park) 2006 Nov;20(12):1537-43; discussion 1544-5, 1549. PMID: 17153907

Recent clinical studies

Etiology

Hendifar AE, Marchevsky AM, Tuli R
J Thorac Oncol 2017 Mar;12(3):425-436. Epub 2016 Nov 24 doi: 10.1016/j.jtho.2016.11.2222. PMID: 27890494
Wolin EM
Chest 2017 May;151(5):1141-1146. Epub 2016 Jun 29 doi: 10.1016/j.chest.2016.06.018. PMID: 27373769
Shimada Y, Niho S, Ishii G, Hishida T, Yoshida J, Nishimura M, Yoh K, Goto K, Ohmatsu H, Ohe Y, Nagai K
Lung Cancer 2012 Mar;75(3):368-73. Epub 2011 Sep 13 doi: 10.1016/j.lungcan.2011.08.012. PMID: 21920624
Hakimi AA, Koi PT, Milhoua PM, Blitman NM, Li M, Hugec V, Dutcher JP, Ghavamian R
Urology 2007 Nov;70(5):878-82. doi: 10.1016/j.urology.2007.06.1124. PMID: 18068443
Modlin IM, Lewis JJ, Ahlman H, Bilchik AJ, Kumar RR
Surg Gynecol Obstet 1993 May;176(5):507-18. PMID: 8386860

Diagnosis

Omiyale AO
World J Gastroenterol 2021 Jul 14;27(26):4172-4181. doi: 10.3748/wjg.v27.i26.4172. PMID: 34326617Free PMC Article
Raiker R, Chauhan A, Hasanein H, Burkeen G, Horn M, Veedu J, Vela C, Arnold S, Kolesar J, Anthony L, Evers BM, Cavnar M
Orphanet J Rare Dis 2019 Nov 21;14(1):266. doi: 10.1186/s13023-019-1230-2. PMID: 31752927Free PMC Article
Hendifar AE, Marchevsky AM, Tuli R
J Thorac Oncol 2017 Mar;12(3):425-436. Epub 2016 Nov 24 doi: 10.1016/j.jtho.2016.11.2222. PMID: 27890494
Wolin EM
Chest 2017 May;151(5):1141-1146. Epub 2016 Jun 29 doi: 10.1016/j.chest.2016.06.018. PMID: 27373769
Shimada Y, Niho S, Ishii G, Hishida T, Yoshida J, Nishimura M, Yoh K, Goto K, Ohmatsu H, Ohe Y, Nagai K
Lung Cancer 2012 Mar;75(3):368-73. Epub 2011 Sep 13 doi: 10.1016/j.lungcan.2011.08.012. PMID: 21920624

Therapy

Hendifar AE, Marchevsky AM, Tuli R
J Thorac Oncol 2017 Mar;12(3):425-436. Epub 2016 Nov 24 doi: 10.1016/j.jtho.2016.11.2222. PMID: 27890494
Wolin EM
Chest 2017 May;151(5):1141-1146. Epub 2016 Jun 29 doi: 10.1016/j.chest.2016.06.018. PMID: 27373769
Wolin EM
Oncologist 2015 Oct;20(10):1123-31. Epub 2015 Aug 25 doi: 10.1634/theoncologist.2015-0198. PMID: 26306904Free PMC Article
Shimada Y, Niho S, Ishii G, Hishida T, Yoshida J, Nishimura M, Yoh K, Goto K, Ohmatsu H, Ohe Y, Nagai K
Lung Cancer 2012 Mar;75(3):368-73. Epub 2011 Sep 13 doi: 10.1016/j.lungcan.2011.08.012. PMID: 21920624
Srirajaskanthan R, Toumpanakis C, Karpathakis A, Marelli L, Quigley AM, Dusmet M, Meyer T, Caplin ME
Lung Cancer 2009 Jul;65(1):68-73. Epub 2008 Dec 12 doi: 10.1016/j.lungcan.2008.10.025. PMID: 19070398

Prognosis

Raiker R, Chauhan A, Hasanein H, Burkeen G, Horn M, Veedu J, Vela C, Arnold S, Kolesar J, Anthony L, Evers BM, Cavnar M
Orphanet J Rare Dis 2019 Nov 21;14(1):266. doi: 10.1186/s13023-019-1230-2. PMID: 31752927Free PMC Article
Shi X, Yu PC, Lei BW, Li CW, Zhang Y, Tan LC, Shi RL, Wang J, Ma B, Xu WB, Wang X, Hu JQ, Huang NS, Wei WJ, Wang Y, Chen TZ, Wang YL, Ji QH
Thyroid 2019 Sep;29(9):1269-1278. Epub 2019 Aug 19 doi: 10.1089/thy.2019.0079. PMID: 31328653
Hendifar AE, Marchevsky AM, Tuli R
J Thorac Oncol 2017 Mar;12(3):425-436. Epub 2016 Nov 24 doi: 10.1016/j.jtho.2016.11.2222. PMID: 27890494
Wolin EM
Chest 2017 May;151(5):1141-1146. Epub 2016 Jun 29 doi: 10.1016/j.chest.2016.06.018. PMID: 27373769
Shimada Y, Niho S, Ishii G, Hishida T, Yoshida J, Nishimura M, Yoh K, Goto K, Ohmatsu H, Ohe Y, Nagai K
Lung Cancer 2012 Mar;75(3):368-73. Epub 2011 Sep 13 doi: 10.1016/j.lungcan.2011.08.012. PMID: 21920624

Clinical prediction guides

Shi X, Yu PC, Lei BW, Li CW, Zhang Y, Tan LC, Shi RL, Wang J, Ma B, Xu WB, Wang X, Hu JQ, Huang NS, Wei WJ, Wang Y, Chen TZ, Wang YL, Ji QH
Thyroid 2019 Sep;29(9):1269-1278. Epub 2019 Aug 19 doi: 10.1089/thy.2019.0079. PMID: 31328653
Metro G, Ricciuti B, Chiari R, Baretti M, Falcinelli L, Giannarelli D, Sidoni A, Mountzios G, Crinò L, Bellezza G, Rebonato A, Ferolla P, Toschi L
Lung Cancer 2016 May;95:82-7. Epub 2016 Mar 15 doi: 10.1016/j.lungcan.2016.03.006. PMID: 27040856

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