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Lymphoma, B-cell, EBV-associated

MedGen UID:
1767418
•Concept ID:
C5436861
•
Neoplastic Process
Synonym: EBV-associated B cell lymphoma

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLymphoma, B-cell, EBV-associated

Professional guidelines

PubMed

'Off-the-shelf' allogeneic antigen-specific adoptive T-cell therapy for the treatment of multiple EBV-associated malignancies.
Sinha D, Srihari S, Beckett K, Le Texier L, Solomon M, Panikkar A, Ambalathingal GR, Lekieffre L, Crooks P, Rehan S, Neller MA, Smith C, Khanna R
J Immunother Cancer 2021 Feb;9(2) doi: 10.1136/jitc-2020-001608. PMID: 33589524Free PMC Article
Lymphoproliferative disorders after solid organ transplantation-classification, incidence, risk factors, early detection and treatment options.
Végso G, Hajdu M, Sebestyén A
Pathol Oncol Res 2011 Sep;17(3):443-54. Epub 2010 Dec 31 doi: 10.1007/s12253-010-9329-8. PMID: 21193979
Treatment options for post-transplant lymphoproliferative disorder and other Epstein-Barr virus-associated malignancies.
Davis JE, Moss DJ
Tissue Antigens 2004 Apr;63(4):285-92. doi: 10.1111/j.0001-2815.2004.00227.x. PMID: 15009802

Recent clinical studies

Etiology

New concepts in EBV-associated B, T, and NK cell lymphoproliferative disorders.
Quintanilla-Martinez L, Swerdlow SH, Tousseyn T, Barrionuevo C, Nakamura S, Jaffe ES
Virchows Arch 2023 Jan;482(1):227-244. Epub 2022 Oct 11 doi: 10.1007/s00428-022-03414-4. PMID: 36216980Free PMC Article
Impact of Epstein-Barr virus infection in patients with inflammatory bowel disease.
Zhang H, Zhao S, Cao Z
Front Immunol 2022;13:1001055. Epub 2022 Oct 28 doi: 10.3389/fimmu.2022.1001055. PMID: 36389673Free PMC Article
Epstein-Barr virus and rheumatoid arthritis.
Balandraud N, Roudier J
Joint Bone Spine 2018 Mar;85(2):165-170. Epub 2017 May 9 doi: 10.1016/j.jbspin.2017.04.011. PMID: 28499895
Cutaneous EBV-related lymphoproliferative disorders.
Gru AA, Jaffe ES
Semin Diagn Pathol 2017 Jan;34(1):60-75. Epub 2016 Dec 7 doi: 10.1053/j.semdp.2016.11.003. PMID: 27988064Free PMC Article
HIV-associated Hodgkin lymphoma.
Carbone A, Gloghini A, Serraino D, Spina M
Curr Opin HIV AIDS 2009 Jan;4(1):3-10. doi: 10.1097/COH.0b013e32831a722b. PMID: 19339934

Diagnosis

New concepts in EBV-associated B, T, and NK cell lymphoproliferative disorders.
Quintanilla-Martinez L, Swerdlow SH, Tousseyn T, Barrionuevo C, Nakamura S, Jaffe ES
Virchows Arch 2023 Jan;482(1):227-244. Epub 2022 Oct 11 doi: 10.1007/s00428-022-03414-4. PMID: 36216980Free PMC Article
Impact of Epstein-Barr virus infection in patients with inflammatory bowel disease.
Zhang H, Zhao S, Cao Z
Front Immunol 2022;13:1001055. Epub 2022 Oct 28 doi: 10.3389/fimmu.2022.1001055. PMID: 36389673Free PMC Article
EBV-Associated Lymphoproliferative Disorders: Update in Classification.
Rezk SA, Weiss LM
Surg Pathol Clin 2019 Sep;12(3):745-770. doi: 10.1016/j.path.2019.03.002. PMID: 31352986
The Epstein-Barr virus and the pathogenesis of lymphoma.
Vockerodt M, Yap LF, Shannon-Lowe C, Curley H, Wei W, Vrzalikova K, Murray PG
J Pathol 2015 Jan;235(2):312-22. doi: 10.1002/path.4459. PMID: 25294567
Pulmonary lymphoid disorders.
Koss MN
Semin Diagn Pathol 1995 May;12(2):158-71. PMID: 7638448

Therapy

Genetically modified CD7-targeting allogeneic CAR-T cell therapy with enhanced efficacy for relapsed/refractory CD7-positive hematological malignancies: a phase I clinical study.
Hu Y, Zhou Y, Zhang M, Zhao H, Wei G, Ge W, Cui Q, Mu Q, Chen G, Han L, Guo T, Cui J, Jiang X, Zheng X, Yu S, Li X, Zhang X, Chen M, Li X, Gao M, Wang K, Zu C, Zhang H, He X, Wang Y, Wang D, Ren J, Huang H
Cell Res 2022 Nov;32(11):995-1007. Epub 2022 Sep 23 doi: 10.1038/s41422-022-00721-y. PMID: 36151216Free PMC Article
Estimating the global burden of Epstein-Barr virus-related cancers.
Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104Free PMC Article
EBV-Associated Lymphoproliferative Disorders: Update in Classification.
Rezk SA, Weiss LM
Surg Pathol Clin 2019 Sep;12(3):745-770. doi: 10.1016/j.path.2019.03.002. PMID: 31352986
T-cell therapies for T-cell lymphoma.
Toner K, Bollard CM, Dave H
Cytotherapy 2019 Sep;21(9):935-942. Epub 2019 Jul 16 doi: 10.1016/j.jcyt.2019.04.058. PMID: 31320195
HIV-associated Hodgkin lymphoma.
Carbone A, Gloghini A, Serraino D, Spina M
Curr Opin HIV AIDS 2009 Jan;4(1):3-10. doi: 10.1097/COH.0b013e32831a722b. PMID: 19339934

Prognosis

Epstein-Barr virus-associated lymphomas decoded.
Bednarska K, Chowdhury R, Tobin JWD, Swain F, Keane C, Boyle S, Khanna R, Gandhi MK
Br J Haematol 2024 Feb;204(2):415-433. Epub 2023 Dec 28 doi: 10.1111/bjh.19255. PMID: 38155519
New concepts in EBV-associated B, T, and NK cell lymphoproliferative disorders.
Quintanilla-Martinez L, Swerdlow SH, Tousseyn T, Barrionuevo C, Nakamura S, Jaffe ES
Virchows Arch 2023 Jan;482(1):227-244. Epub 2022 Oct 11 doi: 10.1007/s00428-022-03414-4. PMID: 36216980Free PMC Article
Impact of Epstein-Barr virus infection in patients with inflammatory bowel disease.
Zhang H, Zhao S, Cao Z
Front Immunol 2022;13:1001055. Epub 2022 Oct 28 doi: 10.3389/fimmu.2022.1001055. PMID: 36389673Free PMC Article
EBV-Associated Lymphoproliferative Disorders: Update in Classification.
Rezk SA, Weiss LM
Surg Pathol Clin 2019 Sep;12(3):745-770. doi: 10.1016/j.path.2019.03.002. PMID: 31352986
EBV in T-/NK-Cell Tumorigenesis.
Kimura H
Adv Exp Med Biol 2018;1045:459-475. doi: 10.1007/978-981-10-7230-7_21. PMID: 29896680

Clinical prediction guides

Genetically modified CD7-targeting allogeneic CAR-T cell therapy with enhanced efficacy for relapsed/refractory CD7-positive hematological malignancies: a phase I clinical study.
Hu Y, Zhou Y, Zhang M, Zhao H, Wei G, Ge W, Cui Q, Mu Q, Chen G, Han L, Guo T, Cui J, Jiang X, Zheng X, Yu S, Li X, Zhang X, Chen M, Li X, Gao M, Wang K, Zu C, Zhang H, He X, Wang Y, Wang D, Ren J, Huang H
Cell Res 2022 Nov;32(11):995-1007. Epub 2022 Sep 23 doi: 10.1038/s41422-022-00721-y. PMID: 36151216Free PMC Article
Estimating the global burden of Epstein-Barr virus-related cancers.
Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104Free PMC Article
Defective Epstein-Barr virus in chronic active infection and haematological malignancy.
Okuno Y, Murata T, Sato Y, Muramatsu H, Ito Y, Watanabe T, Okuno T, Murakami N, Yoshida K, Sawada A, Inoue M, Kawa K, Seto M, Ohshima K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Narita Y, Yoshida M, Goshima F, Kawada JI, Nishida T, Kiyoi H, Kato S, Nakamura S, Morishima S, Yoshikawa T, Fujiwara S, Shimizu N, Isobe Y, Noguchi M, Kikuta A, Iwatsuki K, Takahashi Y, Kojima S, Ogawa S, Kimura H
Nat Microbiol 2019 Mar;4(3):404-413. Epub 2019 Jan 21 doi: 10.1038/s41564-018-0334-0. PMID: 30664667
The Epstein-Barr virus and the pathogenesis of lymphoma.
Vockerodt M, Yap LF, Shannon-Lowe C, Curley H, Wei W, Vrzalikova K, Murray PG
J Pathol 2015 Jan;235(2):312-22. doi: 10.1002/path.4459. PMID: 25294567
HIV-associated Hodgkin lymphoma.
Carbone A, Gloghini A, Serraino D, Spina M
Curr Opin HIV AIDS 2009 Jan;4(1):3-10. doi: 10.1097/COH.0b013e32831a722b. PMID: 19339934

Recent systematic reviews

Risk factors for Epstein Barr virus-associated cancers: a systematic review, critical appraisal, and mapping of the epidemiological evidence.
Bakkalci D, Jia Y, Winter JR, Lewis JE, Taylor GS, Stagg HR
J Glob Health 2020 Jun;10(1):010405. doi: 10.7189/jogh.10.010405. PMID: 32257153Free PMC Article

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