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Advanced Pharyngeal Squamous Cell Carcinoma

MedGen UID:
1769475
Concept ID:
C5420343
Neoplastic Process

Definition

Pharyngeal squamous cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Professional guidelines

PubMed

Eckel HE, Bradley PJ
Adv Otorhinolaryngol 2019;83:47-53. Epub 2019 Feb 12 doi: 10.1159/000492308. PMID: 30943512
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Saba NF, Salama JK, Beitler JJ, Busse PM, Cooper JS, Jones CU, Koyfman S, Quon H, Ridge JA, Siddiqui F, Worden F, Yao M, Yom SS; Expert Panel on Radiation Oncology-Head and Neck Cancer
Head Neck 2016 Jul;38(7):979-86. Epub 2016 Apr 30 doi: 10.1002/hed.24423. PMID: 27131050

Recent clinical studies

Etiology

Xie C, Liao J, Huang C, Wei F, Liu T, Wen W, Sun W
Eur Arch Otorhinolaryngol 2022 Apr;279(4):2099-2107. Epub 2021 Jul 28 doi: 10.1007/s00405-021-07007-w. PMID: 34319483
Echanique KA, Evans LK, Han AY, Chhetri DK, St John MA
Hematol Oncol Clin North Am 2021 Oct;35(5):933-947. Epub 2021 Jul 14 doi: 10.1016/j.hoc.2021.05.005. PMID: 34272102
Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Dillon MT, Harrington KJ
J Clin Oncol 2015 Oct 10;33(29):3251-61. Epub 2015 Sep 8 doi: 10.1200/JCO.2015.60.7804. PMID: 26351347

Diagnosis

Xie C, Liao J, Huang C, Wei F, Liu T, Wen W, Sun W
Eur Arch Otorhinolaryngol 2022 Apr;279(4):2099-2107. Epub 2021 Jul 28 doi: 10.1007/s00405-021-07007-w. PMID: 34319483
Peng Q, Li H, Chen J, Wang Y, Tang Z
J Oral Pathol Med 2020 Apr;49(4):294-304. Epub 2019 Jul 16 doi: 10.1111/jop.12924. PMID: 31310693
Eckel HE, Bradley PJ
Adv Otorhinolaryngol 2019;83:47-53. Epub 2019 Feb 12 doi: 10.1159/000492308. PMID: 30943512
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Wycliffe ND, Grover RS, Kim PD, Simental A Jr
Top Magn Reson Imaging 2007 Aug;18(4):243-58. doi: 10.1097/RMR.0b013e3181570c3f. PMID: 17893590

Therapy

Campbell G, Glazer TA, Kimple RJ, Bruce JY
Curr Treat Options Oncol 2022 Apr;23(4):594-608. Epub 2022 Mar 18 doi: 10.1007/s11864-022-00945-5. PMID: 35303749Free PMC Article
Echanique KA, Evans LK, Han AY, Chhetri DK, St John MA
Hematol Oncol Clin North Am 2021 Oct;35(5):933-947. Epub 2021 Jul 14 doi: 10.1016/j.hoc.2021.05.005. PMID: 34272102
Eckel HE, Bradley PJ
Adv Otorhinolaryngol 2019;83:47-53. Epub 2019 Feb 12 doi: 10.1159/000492308. PMID: 30943512
Dillon MT, Harrington KJ
J Clin Oncol 2015 Oct 10;33(29):3251-61. Epub 2015 Sep 8 doi: 10.1200/JCO.2015.60.7804. PMID: 26351347
Hinerman RW, Amdur RJ, Mendenhall WM, Villaret DB, Robbins KT
Curr Treat Options Oncol 2002 Feb;3(1):41-9. doi: 10.1007/s11864-002-0040-1. PMID: 12057086

Prognosis

Billard-Sandu C, Tao YG, Sablin MP, Dumitrescu G, Billard D, Deutsch E
Eur Arch Otorhinolaryngol 2020 May;277(5):1273-1280. Epub 2020 Mar 11 doi: 10.1007/s00405-020-05891-2. PMID: 32162057
Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Dillon MT, Harrington KJ
J Clin Oncol 2015 Oct 10;33(29):3251-61. Epub 2015 Sep 8 doi: 10.1200/JCO.2015.60.7804. PMID: 26351347
Wycliffe ND, Grover RS, Kim PD, Simental A Jr
Top Magn Reson Imaging 2007 Aug;18(4):243-58. doi: 10.1097/RMR.0b013e3181570c3f. PMID: 17893590

Clinical prediction guides

Kuga R, Yamamoto H, Jiromaru R, Hongo T, Yasumatsu R, Matsuo M, Hashimoto K, Taniguchi M, Nakagawa T, Oda Y
Am J Surg Pathol 2023 Sep 1;47(9):955-966. Epub 2023 Jun 26 doi: 10.1097/PAS.0000000000002086. PMID: 37357948
Meng X, Matsumoto F, Mori T, Miura N, Ino Y, Onidani K, Kobayashi K, Matsuzaki Y, Yoshimoto S, Ikeda K, Honda K
Anticancer Res 2021 Feb;41(2):1089-1099. doi: 10.21873/anticanres.14867. PMID: 33517320
Zhong J, Frood R, Brown P, Nelstrop H, Prestwich R, McDermott G, Currie S, Vaidyanathan S, Scarsbrook AF
Clin Radiol 2021 Jan;76(1):78.e9-78.e17. Epub 2020 Oct 6 doi: 10.1016/j.crad.2020.08.030. PMID: 33036778
Kishimoto Y, Harada H, Funakoshi M, Miyamoto SI, Suehiro A, Kitamura M, Muto M, Tateya I, Omori K
Auris Nasus Larynx 2019 Apr;46(2):279-284. Epub 2018 Sep 8 doi: 10.1016/j.anl.2018.08.008. PMID: 30205915
Arantes LMRB, De Carvalho AC, Melendez ME, Lopes Carvalho A
Expert Rev Mol Diagn 2018 Jan;18(1):85-112. Epub 2017 Nov 20 doi: 10.1080/14737159.2017.1404906. PMID: 29134827

Recent systematic reviews

Razavian NB, D'Agostino RB Jr, Steber CR, Helis CA, Hughes RT
JAMA Netw Open 2023 Feb 1;6(2):e2255209. doi: 10.1001/jamanetworkopen.2022.55209. PMID: 36753275Free PMC Article
Kamal F, Khan MA, Lee-Smith W, Sharma S, Imam Z, Jowhar D, Petryna E, Esswein J, Acharya A, Aziz M, Farooq U, Zafar U, Mcdonough S, Adler DG
Dig Dis Sci 2022 Aug;67(8):3518-3528. Epub 2021 Sep 9 doi: 10.1007/s10620-021-07225-6. PMID: 34505257
De Virgilio A, Russo E, Costantino A, Malvezzi L, Colombo G, Cugini G, Miceli S, Rossi V, Spriano G, Mercante G
Eur Arch Otorhinolaryngol 2020 Oct;277(10):2663-2672. Epub 2020 May 2 doi: 10.1007/s00405-020-05990-0. PMID: 32361771
Kao SS, Peters MD, Krishnan SG, Ooi EH
Laryngoscope 2016 Jul;126(7):1572-80. Epub 2016 Feb 10 doi: 10.1002/lary.25894. PMID: 26865034
Dedivitis RA, Aires FT, Cernea CR, Brandão LG
Head Neck 2015 Nov;37(11):1691-7. Epub 2015 Jun 26 doi: 10.1002/hed.23804. PMID: 24958209

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