U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Transplant Complication

MedGen UID:
1781005
•Concept ID:
C0432485
•
Pathologic Function

Definition

A problem arising from transplantation. [from NCI]

Professional guidelines

PubMed

Comparison of multiple treatments in the management of transplant-related thrombotic microangiopathy: a network meta-analysis.
Yang J, Xu X, Han S, Qi J, Li X, Pan T, Zhang R, Han Y
Ann Hematol 2023 Jan;102(1):31-39. Epub 2022 Dec 22 doi: 10.1007/s00277-022-05069-2. PMID: 36547721
Ibrutinib for the treatment of patients with chronic graft-versus-host disease after failure of one or more lines of systemic therapy.
Rahmat LT, Logan AC
Drugs Today (Barc) 2018 May;54(5):305-313. doi: 10.1358/dot.2018.54.5.2807865. PMID: 29911695
New approaches in the diagnosis, pathophysiology, and treatment of pediatric hematopoietic stem cell transplantation-associated thrombotic microangiopathy.
Jodele S, Dandoy CE, Myers KC, El-Bietar J, Nelson A, Wallace G, Laskin BL
Transfus Apher Sci 2016 Apr;54(2):181-90. Epub 2016 Apr 25 doi: 10.1016/j.transci.2016.04.007. PMID: 27156964Free PMC Article

Recent clinical studies

Etiology

A multicenter randomized-controlled trial of hypothermic oxygenated perfusion (HOPE) for human liver grafts before transplantation.
Schlegel A, Mueller M, Muller X, Eden J, Panconesi R, von Felten S, Steigmiller K, Sousa Da Silva RX, de Rougemont O, Mabrut JY, Lesurtel M, Cerisuelo MC, Heaton ND, Allard MA, Adam R, Monbaliu D, Jochmans I, Haring MPD, Porte RJ, Parente A, Muiesan P, Kron P, Attia M, Kollmann D, Berlakovich G, Rogiers X, Petterson K, Kranich AL, Amberg S, Müllhaupt B, Clavien PA, Dutkowski P
J Hepatol 2023 Apr;78(4):783-793. Epub 2023 Jan 19 doi: 10.1016/j.jhep.2022.12.030. PMID: 36681160
Hyperammonemia syndrome post-lung transplantation: Case series and systematic review of literature.
Buzo BF, Preiksaitis JK, Halloran K, Nagendran J, Townsend DR, Zelyas N, Sligl WI
Transpl Infect Dis 2022 Dec;24(6):e13940. Epub 2022 Sep 6 doi: 10.1111/tid.13940. PMID: 36039822
Early Postoperative Management of Lung Transplant Recipients.
Trinh BN, Brzezinski M, Kukreja J
Thorac Surg Clin 2022 May;32(2):185-195. doi: 10.1016/j.thorsurg.2021.11.006. PMID: 35512937
Surgical complications after living and deceased donor liver transplant: The NSQIP transplant experience.
Amara D, Parekh J, Sudan D, Elias N, Foley DP, Conzen K, Grieco A, Braun HJ, Greenstein S, Byrd C, Ko C, Hirose R
Clin Transplant 2022 Jun;36(6):e14610. Epub 2022 May 4 doi: 10.1111/ctr.14610. PMID: 35143698
Post-transplantation Development of Food Allergies.
Newman EN, Firszt R
Curr Allergy Asthma Rep 2018 Jan 29;18(1):4. doi: 10.1007/s11882-018-0760-3. PMID: 29380059

Diagnosis

Transplant-associated thrombotic microangiopathy: elucidating prevention strategies and identifying high-risk patients.
Jodele S, Sabulski A
Expert Rev Hematol 2021 Aug;14(8):751-763. Epub 2021 Aug 4 doi: 10.1080/17474086.2021.1960816. PMID: 34301169
BK Polyomavirus Nephropathy in Kidney Transplantation: Balancing Rejection and Infection.
Shen CL, Wu BS, Lien TJ, Yang AH, Yang CY
Viruses 2021 Mar 16;13(3) doi: 10.3390/v13030487. PMID: 33809472Free PMC Article
Nocardia infections in the transplanted host.
Hemmersbach-Miller M, Stout JE, Woodworth MH, Cox GM, Saullo JL
Transpl Infect Dis 2018 Aug;20(4):e12902. Epub 2018 May 7 doi: 10.1111/tid.12902. PMID: 29668123Free PMC Article
Chronic graft-versus-host disease: biological insights from preclinical and clinical studies.
MacDonald KP, Hill GR, Blazar BR
Blood 2017 Jan 5;129(1):13-21. Epub 2016 Nov 7 doi: 10.1182/blood-2016-06-686618. PMID: 27821504Free PMC Article
Pulmonary hypertension after hematopoietic stem cell transplantation.
Dandoy CE, Hirsch R, Chima R, Davies SM, Jodele S
Biol Blood Marrow Transplant 2013 Nov;19(11):1546-56. Epub 2013 Jul 23 doi: 10.1016/j.bbmt.2013.07.017. PMID: 23891748

Therapy

A multicenter randomized-controlled trial of hypothermic oxygenated perfusion (HOPE) for human liver grafts before transplantation.
Schlegel A, Mueller M, Muller X, Eden J, Panconesi R, von Felten S, Steigmiller K, Sousa Da Silva RX, de Rougemont O, Mabrut JY, Lesurtel M, Cerisuelo MC, Heaton ND, Allard MA, Adam R, Monbaliu D, Jochmans I, Haring MPD, Porte RJ, Parente A, Muiesan P, Kron P, Attia M, Kollmann D, Berlakovich G, Rogiers X, Petterson K, Kranich AL, Amberg S, Müllhaupt B, Clavien PA, Dutkowski P
J Hepatol 2023 Apr;78(4):783-793. Epub 2023 Jan 19 doi: 10.1016/j.jhep.2022.12.030. PMID: 36681160
Hyperammonemia syndrome post-lung transplantation: Case series and systematic review of literature.
Buzo BF, Preiksaitis JK, Halloran K, Nagendran J, Townsend DR, Zelyas N, Sligl WI
Transpl Infect Dis 2022 Dec;24(6):e13940. Epub 2022 Sep 6 doi: 10.1111/tid.13940. PMID: 36039822
Early Postoperative Management of Lung Transplant Recipients.
Trinh BN, Brzezinski M, Kukreja J
Thorac Surg Clin 2022 May;32(2):185-195. doi: 10.1016/j.thorsurg.2021.11.006. PMID: 35512937
Post-transplantation Development of Food Allergies.
Newman EN, Firszt R
Curr Allergy Asthma Rep 2018 Jan 29;18(1):4. doi: 10.1007/s11882-018-0760-3. PMID: 29380059
Oral graft-versus-host disease.
Imanguli MM, Alevizos I, Brown R, Pavletic SZ, Atkinson JC
Oral Dis 2008 Jul;14(5):396-412. doi: 10.1111/j.1601-0825.2008.01448.x. PMID: 18593456Free PMC Article

Prognosis

Comparison of multiple treatments in the management of transplant-related thrombotic microangiopathy: a network meta-analysis.
Yang J, Xu X, Han S, Qi J, Li X, Pan T, Zhang R, Han Y
Ann Hematol 2023 Jan;102(1):31-39. Epub 2022 Dec 22 doi: 10.1007/s00277-022-05069-2. PMID: 36547721
Hyperammonemia syndrome post-lung transplantation: Case series and systematic review of literature.
Buzo BF, Preiksaitis JK, Halloran K, Nagendran J, Townsend DR, Zelyas N, Sligl WI
Transpl Infect Dis 2022 Dec;24(6):e13940. Epub 2022 Sep 6 doi: 10.1111/tid.13940. PMID: 36039822
Transplant-associated thrombotic microangiopathy: elucidating prevention strategies and identifying high-risk patients.
Jodele S, Sabulski A
Expert Rev Hematol 2021 Aug;14(8):751-763. Epub 2021 Aug 4 doi: 10.1080/17474086.2021.1960816. PMID: 34301169
Incidence, Risk Factors for and Outcomes of Transplant-Associated Thrombotic Microangiopathy.
Epperla N, Li A, Logan B, Fretham C, Chhabra S, Aljurf M, Chee L, Copelan E, Freytes CO, Hematti P, Lazarus HM, Litzow M, Nishihori T, Olsson RF, Prestidge T, Saber W, Wirk B, Yared JA, Loren A, Pasquini M
Br J Haematol 2020 Jun;189(6):1171-1181. Epub 2020 Mar 2 doi: 10.1111/bjh.16457. PMID: 32124435Free PMC Article
Early versus late ureteric stent removal after kidney transplantation.
Thompson ER, Hosgood SA, Nicholson ML, Wilson CH
Cochrane Database Syst Rev 2018 Jan 29;1(1):CD011455. doi: 10.1002/14651858.CD011455.pub2. PMID: 29376218Free PMC Article

Clinical prediction guides

A multicenter randomized-controlled trial of hypothermic oxygenated perfusion (HOPE) for human liver grafts before transplantation.
Schlegel A, Mueller M, Muller X, Eden J, Panconesi R, von Felten S, Steigmiller K, Sousa Da Silva RX, de Rougemont O, Mabrut JY, Lesurtel M, Cerisuelo MC, Heaton ND, Allard MA, Adam R, Monbaliu D, Jochmans I, Haring MPD, Porte RJ, Parente A, Muiesan P, Kron P, Attia M, Kollmann D, Berlakovich G, Rogiers X, Petterson K, Kranich AL, Amberg S, Müllhaupt B, Clavien PA, Dutkowski P
J Hepatol 2023 Apr;78(4):783-793. Epub 2023 Jan 19 doi: 10.1016/j.jhep.2022.12.030. PMID: 36681160
Predictors of 1-year mortality after adult lung transplantation: Systematic review and meta-analyses.
Foroutan F, Malik A, Clark KE, Buchan TA, Yang H, Cheong GHL, Pezzutti O, Kim I, Gupta R, Tan C, Samman A, Friesen EL, Akhtar A, Rigobon A, Stein M, Yepes-Nuñez JJ, Heels-Ansdell D, Sidhu A, Guyatt G, Meade MO
J Heart Lung Transplant 2022 Jul;41(7):937-951. Epub 2022 Mar 29 doi: 10.1016/j.healun.2022.03.017. PMID: 35570129
Rational use of chronic graft-versus-host treatment alternatives: A systematic review.
Yeral M, Boğa C
Transfus Apher Sci 2022 Feb;61(1):103371. Epub 2022 Jan 24 doi: 10.1016/j.transci.2022.103371. PMID: 35115251
Transplant-associated thrombotic microangiopathy: elucidating prevention strategies and identifying high-risk patients.
Jodele S, Sabulski A
Expert Rev Hematol 2021 Aug;14(8):751-763. Epub 2021 Aug 4 doi: 10.1080/17474086.2021.1960816. PMID: 34301169
Clinical predictors and outcome implications of early readmission in lung transplant recipients.
Osho AA, Castleberry AW, Yerokun BA, Mulvihill MS, Rucker J, Snyder LD, Davis RD, Hartwig MG
J Heart Lung Transplant 2017 May;36(5):546-553. Epub 2016 Nov 10 doi: 10.1016/j.healun.2016.11.001. PMID: 27932071Free PMC Article

Recent systematic reviews

Hyperammonemia syndrome post-lung transplantation: Case series and systematic review of literature.
Buzo BF, Preiksaitis JK, Halloran K, Nagendran J, Townsend DR, Zelyas N, Sligl WI
Transpl Infect Dis 2022 Dec;24(6):e13940. Epub 2022 Sep 6 doi: 10.1111/tid.13940. PMID: 36039822
Predictors of 1-year mortality after adult lung transplantation: Systematic review and meta-analyses.
Foroutan F, Malik A, Clark KE, Buchan TA, Yang H, Cheong GHL, Pezzutti O, Kim I, Gupta R, Tan C, Samman A, Friesen EL, Akhtar A, Rigobon A, Stein M, Yepes-Nuñez JJ, Heels-Ansdell D, Sidhu A, Guyatt G, Meade MO
J Heart Lung Transplant 2022 Jul;41(7):937-951. Epub 2022 Mar 29 doi: 10.1016/j.healun.2022.03.017. PMID: 35570129
The role of preoperative optimization of the nutritional status on the improvement of short-term outcomes after liver transplantation? A review of the literature and expert panel recommendations.
Victor DW 3rd, Zanetto A, Montano-Loza AJ, Heimbach JK, Towey J, Spiro M, Raptis DA, Burra P; ERAS4OLT.org Working Group
Clin Transplant 2022 Oct;36(10):e14647. doi: 10.1111/ctr.14647. PMID: 35303370Free PMC Article
Rational use of chronic graft-versus-host treatment alternatives: A systematic review.
Yeral M, Boğa C
Transfus Apher Sci 2022 Feb;61(1):103371. Epub 2022 Jan 24 doi: 10.1016/j.transci.2022.103371. PMID: 35115251
Early versus late ureteric stent removal after kidney transplantation.
Thompson ER, Hosgood SA, Nicholson ML, Wilson CH
Cochrane Database Syst Rev 2018 Jan 29;1(1):CD011455. doi: 10.1002/14651858.CD011455.pub2. PMID: 29376218Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...