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Podocyte microvillous transformation

MedGen UID:
1781390
•Concept ID:
C5539446
•
Finding
HPO: HP:0033238

Definition

Cytoplasmic projections into the urinary space from the luminal side of the podocyte. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPodocyte microvillous transformation

Recent clinical studies

Etiology

Focal Segmental Glomerulosclerosis.
Rosenberg AZ, Kopp JB
Clin J Am Soc Nephrol 2017 Mar 7;12(3):502-517. Epub 2017 Feb 27 doi: 10.2215/CJN.05960616. PMID: 28242845Free PMC Article

Diagnosis

Ultrastructural Characterization of Proteinuric Patients Predicts Clinical Outcomes.
Royal V, Zee J, Liu Q, Avila-Casado C, Smith AR, Liu G, Mariani LH, Hewitt S, Holzman LB, Gillespie BW, Hodgin JB, Barisoni L
J Am Soc Nephrol 2020 Apr;31(4):841-854. Epub 2020 Feb 21 doi: 10.1681/ASN.2019080825. PMID: 32086276Free PMC Article

Therapy

Focal Segmental Glomerulosclerosis.
Rosenberg AZ, Kopp JB
Clin J Am Soc Nephrol 2017 Mar 7;12(3):502-517. Epub 2017 Feb 27 doi: 10.2215/CJN.05960616. PMID: 28242845Free PMC Article

Prognosis

Ultrastructural Characterization of Proteinuric Patients Predicts Clinical Outcomes.
Royal V, Zee J, Liu Q, Avila-Casado C, Smith AR, Liu G, Mariani LH, Hewitt S, Holzman LB, Gillespie BW, Hodgin JB, Barisoni L
J Am Soc Nephrol 2020 Apr;31(4):841-854. Epub 2020 Feb 21 doi: 10.1681/ASN.2019080825. PMID: 32086276Free PMC Article
Focal Segmental Glomerulosclerosis.
Rosenberg AZ, Kopp JB
Clin J Am Soc Nephrol 2017 Mar 7;12(3):502-517. Epub 2017 Feb 27 doi: 10.2215/CJN.05960616. PMID: 28242845Free PMC Article

Clinical prediction guides

Ultrastructural Characterization of Proteinuric Patients Predicts Clinical Outcomes.
Royal V, Zee J, Liu Q, Avila-Casado C, Smith AR, Liu G, Mariani LH, Hewitt S, Holzman LB, Gillespie BW, Hodgin JB, Barisoni L
J Am Soc Nephrol 2020 Apr;31(4):841-854. Epub 2020 Feb 21 doi: 10.1681/ASN.2019080825. PMID: 32086276Free PMC Article
Reproducibility of the NEPTUNE descriptor-based scoring system on whole-slide images and histologic and ultrastructural digital images.
Barisoni L, Troost JP, Nast C, Bagnasco S, Avila-Casado C, Hodgin J, Palmer M, Rosenberg A, Gasim A, Liensziewski C, Merlino L, Chien HP, Chang A, Meehan SM, Gaut J, Song P, Holzman L, Gibson D, Kretzler M, Gillespie BW, Hewitt SM
Mod Pathol 2016 Jul;29(7):671-84. Epub 2016 Apr 22 doi: 10.1038/modpathol.2016.58. PMID: 27102348Free PMC Article

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