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Refractory Giant Cell Glioblastoma

MedGen UID:
1781610
Concept ID:
C5447549
Neoplastic Process

Definition

Giant cell glioblastoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Giant Cell Glioblastoma

Professional guidelines

PubMed

Datta S, Luthra R, Bharadvaja N
Anticancer Agents Med Chem 2022;22(13):2367-2384. doi: 10.2174/1871520622666211221144739. PMID: 34939551
Qazi MA, Vora P, Venugopal C, Sidhu SS, Moffat J, Swanton C, Singh SK
Ann Oncol 2017 Jul 1;28(7):1448-1456. doi: 10.1093/annonc/mdx169. PMID: 28407030
Theeler BJ, Gilbert MR
BMC Med 2015 Dec 8;13:293. doi: 10.1186/s12916-015-0536-8. PMID: 26646075Free PMC Article

Recent clinical studies

Etiology

Wang JZ, Nassiri F, Bi L, Zadeh G
Adv Exp Med Biol 2023;1416:189-198. doi: 10.1007/978-3-031-29750-2_14. PMID: 37432628
Bose S, Barroso M, Chheda MG, Clevers H, Elez E, Kaochar S, Kopetz SE, Li XN, Meric-Bernstam F, Meyer CA, Mou H, Naegle KM, Pera MF, Perova Z, Politi KA, Raphael BJ, Robson P, Sears RC, Tabernero J, Tuveson DA, Welm AL, Welm BE, Willey CD, Salnikow K, Chuang JH, Shen X
Cancer Cell 2022 Dec 12;40(12):1448-1453. Epub 2022 Oct 20 doi: 10.1016/j.ccell.2022.09.017. PMID: 36270276Free PMC Article
Wen PY, Stein A, van den Bent M, De Greve J, Wick A, de Vos FYFL, von Bubnoff N, van Linde ME, Lai A, Prager GW, Campone M, Fasolo A, Lopez-Martin JA, Kim TM, Mason WP, Hofheinz RD, Blay JY, Cho DC, Gazzah A, Pouessel D, Yachnin J, Boran A, Burgess P, Ilankumaran P, Gasal E, Subbiah V
Lancet Oncol 2022 Jan;23(1):53-64. Epub 2021 Nov 24 doi: 10.1016/S1470-2045(21)00578-7. PMID: 34838156
McFaline-Figueroa JR, Lee EQ
Am J Med 2018 Aug;131(8):874-882. Epub 2018 Jan 31 doi: 10.1016/j.amjmed.2017.12.039. PMID: 29371158
Kizilarslanoglu MC, Aksoy S, Yildirim NO, Ararat E, Sahin I, Altundag K
J BUON 2011 Jul-Sep;16(3):547-50. PMID: 22006764

Diagnosis

Eisenbarth D, Wang YA
Oncogene 2023 Jun;42(27):2155-2165. Epub 2023 Jun 5 doi: 10.1038/s41388-023-02738-y. PMID: 37277603Free PMC Article
Datta S, Luthra R, Bharadvaja N
Anticancer Agents Med Chem 2022;22(13):2367-2384. doi: 10.2174/1871520622666211221144739. PMID: 34939551
McFaline-Figueroa JR, Lee EQ
Am J Med 2018 Aug;131(8):874-882. Epub 2018 Jan 31 doi: 10.1016/j.amjmed.2017.12.039. PMID: 29371158
Wang Q, Hu B, Hu X, Kim H, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, Zheng S, Chang E, Sauvé CG, Olar A, Lan ZD, Finocchiaro G, Phillips JJ, Berger MS, Gabrusiewicz KR, Wang G, Eskilsson E, Hu J, Mikkelsen T, DePinho RA, Muller F, Heimberger AB, Sulman EP, Nam DH, Verhaak RGW
Cancer Cell 2017 Jul 10;32(1):42-56.e6. doi: 10.1016/j.ccell.2017.06.003. PMID: 28697342Free PMC Article
Katoh M, Nakagama H
Med Res Rev 2014 Mar;34(2):280-300. Epub 2013 May 21 doi: 10.1002/med.21288. PMID: 23696246

Therapy

Li Y, Gao Z, Wang Y, Pang B, Zhang B, Hu R, Wang Y, Liu C, Zhang X, Yang J, Mei M, Wang Y, Zhou X, Li M, Ren Y
Nat Commun 2023 Jul 10;14(1):4062. doi: 10.1038/s41467-023-39845-z. PMID: 37429858Free PMC Article
Wen PY, Stein A, van den Bent M, De Greve J, Wick A, de Vos FYFL, von Bubnoff N, van Linde ME, Lai A, Prager GW, Campone M, Fasolo A, Lopez-Martin JA, Kim TM, Mason WP, Hofheinz RD, Blay JY, Cho DC, Gazzah A, Pouessel D, Yachnin J, Boran A, Burgess P, Ilankumaran P, Gasal E, Subbiah V
Lancet Oncol 2022 Jan;23(1):53-64. Epub 2021 Nov 24 doi: 10.1016/S1470-2045(21)00578-7. PMID: 34838156
Vitanza NA, Johnson AJ, Wilson AL, Brown C, Yokoyama JK, Künkele A, Chang CA, Rawlings-Rhea S, Huang W, Seidel K, Albert CM, Pinto N, Gust J, Finn LS, Ojemann JG, Wright J, Orentas RJ, Baldwin M, Gardner RA, Jensen MC, Park JR
Nat Med 2021 Sep;27(9):1544-1552. Epub 2021 Jul 12 doi: 10.1038/s41591-021-01404-8. PMID: 34253928
Hu H, Mu Q, Bao Z, Chen Y, Liu Y, Chen J, Wang K, Wang Z, Nam Y, Jiang B, Sa JK, Cho HJ, Her NG, Zhang C, Zhao Z, Zhang Y, Zeng F, Wu F, Kang X, Liu Y, Qian Z, Wang Z, Huang R, Wang Q, Zhang W, Qiu X, Li W, Nam DH, Fan X, Wang J, Jiang T
Cell 2018 Nov 29;175(6):1665-1678.e18. Epub 2018 Oct 18 doi: 10.1016/j.cell.2018.09.038. PMID: 30343896
Katoh M, Nakagama H
Med Res Rev 2014 Mar;34(2):280-300. Epub 2013 May 21 doi: 10.1002/med.21288. PMID: 23696246

Prognosis

Li Y, Gao Z, Wang Y, Pang B, Zhang B, Hu R, Wang Y, Liu C, Zhang X, Yang J, Mei M, Wang Y, Zhou X, Li M, Ren Y
Nat Commun 2023 Jul 10;14(1):4062. doi: 10.1038/s41467-023-39845-z. PMID: 37429858Free PMC Article
Segura-Collar B, Hiller-Vallina S, de Dios O, Caamaño-Moreno M, Mondejar-Ruescas L, Sepulveda-Sanchez JM, Gargini R
Acta Neuropathol Commun 2023 May 10;11(1):79. doi: 10.1186/s40478-023-01569-y. PMID: 37165457Free PMC Article
Kim Y, Varn FS, Park SH, Yoon BW, Park HR, Lee C, Verhaak RGW, Paek SH
Acta Neuropathol Commun 2021 Mar 24;9(1):50. doi: 10.1186/s40478-021-01151-4. PMID: 33762019Free PMC Article
Hu H, Mu Q, Bao Z, Chen Y, Liu Y, Chen J, Wang K, Wang Z, Nam Y, Jiang B, Sa JK, Cho HJ, Her NG, Zhang C, Zhao Z, Zhang Y, Zeng F, Wu F, Kang X, Liu Y, Qian Z, Wang Z, Huang R, Wang Q, Zhang W, Qiu X, Li W, Nam DH, Fan X, Wang J, Jiang T
Cell 2018 Nov 29;175(6):1665-1678.e18. Epub 2018 Oct 18 doi: 10.1016/j.cell.2018.09.038. PMID: 30343896
McFaline-Figueroa JR, Lee EQ
Am J Med 2018 Aug;131(8):874-882. Epub 2018 Jan 31 doi: 10.1016/j.amjmed.2017.12.039. PMID: 29371158

Clinical prediction guides

Guo X, Chang M, Wang Y, Xing B, Ma W
Int J Biol Sci 2023;19(12):3762-3780. Epub 2023 Jul 24 doi: 10.7150/ijbs.85813. PMID: 37564196Free PMC Article
Segura-Collar B, Hiller-Vallina S, de Dios O, Caamaño-Moreno M, Mondejar-Ruescas L, Sepulveda-Sanchez JM, Gargini R
Acta Neuropathol Commun 2023 May 10;11(1):79. doi: 10.1186/s40478-023-01569-y. PMID: 37165457Free PMC Article
Wu H, Guo C, Wang C, Xu J, Zheng S, Duan J, Li Y, Bai H, Xu Q, Ning F, Wang F, Yang Q
Cancer Sci 2023 Jun;114(6):2609-2621. Epub 2023 Mar 10 doi: 10.1111/cas.15773. PMID: 36853018Free PMC Article
Bose S, Barroso M, Chheda MG, Clevers H, Elez E, Kaochar S, Kopetz SE, Li XN, Meric-Bernstam F, Meyer CA, Mou H, Naegle KM, Pera MF, Perova Z, Politi KA, Raphael BJ, Robson P, Sears RC, Tabernero J, Tuveson DA, Welm AL, Welm BE, Willey CD, Salnikow K, Chuang JH, Shen X
Cancer Cell 2022 Dec 12;40(12):1448-1453. Epub 2022 Oct 20 doi: 10.1016/j.ccell.2022.09.017. PMID: 36270276Free PMC Article
Lamano JB, Ampie L, Choy W, Kesavabhotla K, DiDomenico JD, Oyon DE, Parsa AT, Bloch O
J Neurooncol 2016 Mar;127(1):1-13. Epub 2015 Dec 5 doi: 10.1007/s11060-015-2018-4. PMID: 26638171Free PMC Article

Recent systematic reviews

Bateman ME, Strong AL, Gimble JM, Bunnell BA
Stem Cells 2018 Sep;36(9):1311-1328. Epub 2018 Jul 16 doi: 10.1002/stem.2847. PMID: 29761573

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