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Anti-desmoglein-1 antibody positivity

MedGen UID:
1782223
•Concept ID:
C5539863
•
Laboratory or Test Result
HPO: HP:4000013

Definition

The presence of autoantibodies (immunoglobulins) in the serum that react against desmoglein-1, a dermal cell adhesion molecule. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-desmoglein-1 antibody positivity

Professional guidelines

PubMed

Rituximab Therapy for Treatment of Pemphigus in Southeast Asians.
Kanokrungsee S, Anuntrangsee T, Tankunakorn J, Srisuwanwattana P, Suchonwanit P, Chanprapaph K
Drug Des Devel Ther 2021;15:1677-1690. Epub 2021 Apr 22 doi: 10.2147/DDDT.S306046. PMID: 33911853Free PMC Article
Rituximab treatment of severe pemphigus: long-term results including immunologic follow-up.
Reguiai Z, Tabary T, Maizières M, Bernard P
J Am Acad Dermatol 2012 Oct;67(4):623-9. Epub 2012 Jan 20 doi: 10.1016/j.jaad.2011.12.019. PMID: 22261417
ELISA testing of anti-desmoglein 1 and 3 antibodies in the management of pemphigus.
Abasq C, Mouquet H, Gilbert D, Tron F, Grassi V, Musette P, Joly P
Arch Dermatol 2009 May;145(5):529-35. doi: 10.1001/archdermatol.2009.9. PMID: 19451496

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