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Elevated functional residual capacity

MedGen UID:
1782732
•Concept ID:
C5539792
•
Finding
HPO: HP:0033751

Definition

An abnormal increase in the volume remaining in the lungs after a normal, passive exhalation. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVElevated functional residual capacity

Professional guidelines

PubMed

Lung function is abnormal in 3-month-old infants with cystic fibrosis diagnosed by newborn screening.
Hoo AF, Thia LP, Nguyen TT, Bush A, Chudleigh J, Lum S, Ahmed D, Balfour Lynn I, Carr SB, Chavasse RJ, Costeloe KL, Price J, Shankar A, Wallis C, Wyatt HA, Wade A, Stocks J; London Cystic Fibrosis Collaboration
Thorax 2012 Oct;67(10):874-81. Epub 2012 Jun 29 doi: 10.1136/thoraxjnl-2012-201747. PMID: 22752198
Effect of uremia and its treatment on pulmonary function.
Prezant DJ
Lung 1990;168(1):1-14. doi: 10.1007/BF02719668. PMID: 2105408
Insulin antibodies in juvenile diabetes mellitus. Correlations to diabetic stability, insulin requirement and duration of insulin treatment.
Keilacker H, Rjasanowski I, Ziegler M, Michaelis D, Woltanski KP, Besch W
Horm Metab Res 1982 May;14(5):227-32. doi: 10.1055/s-2007-1018979. PMID: 7047344

Recent clinical studies

Etiology

The Impact of Positive Expiratory Pressure Therapy on Hyperinflation in Patients With COPD.
de Macedo JRFF, Conceiçãodos Dos Santos ED, Reychler G, Poncin W
Respir Care 2024 Feb 28;69(3):366-375. doi: 10.4187/respcare.11039. PMID: 38416659Free PMC Article
Altered airway mechanics in the context of obesity and asthma.
Bates JHT, Peters U, Daphtary N, MacLean ES, Hodgdon K, Kaminsky DA, Bhatawadekar S, Dixon AE
J Appl Physiol (1985) 2021 Jan 1;130(1):36-47. Epub 2020 Oct 29 doi: 10.1152/japplphysiol.00666.2020. PMID: 33119471Free PMC Article
Measuring the effects of bronchial thermoplasty using oscillometry.
Langton D, Ing A, Sha J, Bennetts K, Hersch N, Kwok M, Plummer V, Thien F, Farah C
Respirology 2019 May;24(5):431-436. Epub 2018 Nov 12 doi: 10.1111/resp.13439. PMID: 30419608
Preoxygenation: Physiologic Basis, Benefits, and Potential Risks.
Nimmagadda U, Salem MR, Crystal GJ
Anesth Analg 2017 Feb;124(2):507-517. doi: 10.1213/ANE.0000000000001589. PMID: 28099321
Prediction of bronchopulmonary dysplasia.
May C, Patel S, Kennedy C, Pollina E, Rafferty GF, Peacock JL, Greenough A
Arch Dis Child Fetal Neonatal Ed 2011 Nov;96(6):F410-6. Epub 2011 Feb 28 doi: 10.1136/adc.2010.189597. PMID: 21362700

Diagnosis

Imaging-based assessment of lung function in a population cooking indoors with biomass fuel: a pilot study.
Kizhakke Puliyakote AS, Stapleton EM, Durairaj K, Karuppusamy K, Kathiresan GB, Shanmugam K, Abdul Rahim S, Navaneethakrishnan S, Bilas M, Huang R, Metwali N, Jeronimo M, Chan KS, Guo J, Nagpal P, Peters TM, Thorne PS, Comellas AP, Hoffman EA
J Appl Physiol (1985) 2023 Mar 1;134(3):710-721. Epub 2023 Feb 9 doi: 10.1152/japplphysiol.00286.2022. PMID: 36759166Free PMC Article
Elevated serum IgE, oral corticosteroid dependence and IL-17/22 expression in highly neutrophilic asthma.
Bullone M, Carriero V, Bertolini F, Folino A, Mannelli A, Di Stefano A, Gnemmi I, Torchio R, Ricciardolo FLM
Eur Respir J 2019 Nov;54(5) Epub 2019 Nov 7 doi: 10.1183/13993003.00068-2019. PMID: 31439682
The similarities and differences between pleuroparenchymal fibroelastosis and idiopathic pulmonary fibrosis.
Ishii H, Kinoshita Y, Kushima H, Nagata N, Watanabe K
Chron Respir Dis 2019 Jan-Dec;16:1479973119867945. doi: 10.1177/1479973119867945. PMID: 31387379Free PMC Article
Cancer stem cells as functional biomarkers.
D'Andrea V, Panarese A, Tonda M, Biffoni M, Monti M
Cancer Biomark 2017 Sep 7;20(3):231-234. doi: 10.3233/CBM-151176. PMID: 28800308
Prediction of bronchopulmonary dysplasia.
May C, Patel S, Kennedy C, Pollina E, Rafferty GF, Peacock JL, Greenough A
Arch Dis Child Fetal Neonatal Ed 2011 Nov;96(6):F410-6. Epub 2011 Feb 28 doi: 10.1136/adc.2010.189597. PMID: 21362700

Therapy

The Impact of Positive Expiratory Pressure Therapy on Hyperinflation in Patients With COPD.
de Macedo JRFF, Conceiçãodos Dos Santos ED, Reychler G, Poncin W
Respir Care 2024 Feb 28;69(3):366-375. doi: 10.4187/respcare.11039. PMID: 38416659Free PMC Article
Imaging-based assessment of lung function in a population cooking indoors with biomass fuel: a pilot study.
Kizhakke Puliyakote AS, Stapleton EM, Durairaj K, Karuppusamy K, Kathiresan GB, Shanmugam K, Abdul Rahim S, Navaneethakrishnan S, Bilas M, Huang R, Metwali N, Jeronimo M, Chan KS, Guo J, Nagpal P, Peters TM, Thorne PS, Comellas AP, Hoffman EA
J Appl Physiol (1985) 2023 Mar 1;134(3):710-721. Epub 2023 Feb 9 doi: 10.1152/japplphysiol.00286.2022. PMID: 36759166Free PMC Article
Systemic but not local rehydration restores dehydration-induced changes in pulmonary function in healthy adults.
Marshall H, Gibson OR, Romer LM, Illidi C, Hull JH, Kippelen P
J Appl Physiol (1985) 2021 Mar 1;130(3):517-527. Epub 2020 Dec 10 doi: 10.1152/japplphysiol.00311.2020. PMID: 33300853
The similarities and differences between pleuroparenchymal fibroelastosis and idiopathic pulmonary fibrosis.
Ishii H, Kinoshita Y, Kushima H, Nagata N, Watanabe K
Chron Respir Dis 2019 Jan-Dec;16:1479973119867945. doi: 10.1177/1479973119867945. PMID: 31387379Free PMC Article
Preoxygenation: Physiologic Basis, Benefits, and Potential Risks.
Nimmagadda U, Salem MR, Crystal GJ
Anesth Analg 2017 Feb;124(2):507-517. doi: 10.1213/ANE.0000000000001589. PMID: 28099321

Prognosis

Elevated serum IgE, oral corticosteroid dependence and IL-17/22 expression in highly neutrophilic asthma.
Bullone M, Carriero V, Bertolini F, Folino A, Mannelli A, Di Stefano A, Gnemmi I, Torchio R, Ricciardolo FLM
Eur Respir J 2019 Nov;54(5) Epub 2019 Nov 7 doi: 10.1183/13993003.00068-2019. PMID: 31439682
The similarities and differences between pleuroparenchymal fibroelastosis and idiopathic pulmonary fibrosis.
Ishii H, Kinoshita Y, Kushima H, Nagata N, Watanabe K
Chron Respir Dis 2019 Jan-Dec;16:1479973119867945. doi: 10.1177/1479973119867945. PMID: 31387379Free PMC Article
Elevated lung volumes in neonates with bronchopulmonary dysplasia measured via MRI.
Yoder LM, Higano NS, Schapiro AH, Fleck RJ, Hysinger EB, Bates AJ, Kingma PS, Merhar SL, Fain SB, Woods JC
Pediatr Pulmonol 2019 Aug;54(8):1311-1318. Epub 2019 May 27 doi: 10.1002/ppul.24378. PMID: 31134768
Measuring the effects of bronchial thermoplasty using oscillometry.
Langton D, Ing A, Sha J, Bennetts K, Hersch N, Kwok M, Plummer V, Thien F, Farah C
Respirology 2019 May;24(5):431-436. Epub 2018 Nov 12 doi: 10.1111/resp.13439. PMID: 30419608
Prediction of bronchopulmonary dysplasia.
May C, Patel S, Kennedy C, Pollina E, Rafferty GF, Peacock JL, Greenough A
Arch Dis Child Fetal Neonatal Ed 2011 Nov;96(6):F410-6. Epub 2011 Feb 28 doi: 10.1136/adc.2010.189597. PMID: 21362700

Clinical prediction guides

Measuring the effects of bronchial thermoplasty using oscillometry.
Langton D, Ing A, Sha J, Bennetts K, Hersch N, Kwok M, Plummer V, Thien F, Farah C
Respirology 2019 May;24(5):431-436. Epub 2018 Nov 12 doi: 10.1111/resp.13439. PMID: 30419608
Molecular sources of residual cardiovascular risk, clinical signals, and innovative solutions: relationship with subclinical disease, undertreatment, and poor adherence: implications of new evidence upon optimizing cardiovascular patient outcomes.
Kones R
Vasc Health Risk Manag 2013;9:617-70. Epub 2013 Oct 21 doi: 10.2147/VHRM.S37119. PMID: 24174878Free PMC Article
Correlation of early functional capacity with biventricular function and residual pulmonary artery hypertension following mitral valve replacement surgery.
Puri S, Mehta V, Ahmed F, Banerjee A, Yusuf J, Mukhopadhyay S, Tyagi S
J Cardiopulm Rehabil Prev 2013 Jul-Aug;33(4):244-8. doi: 10.1097/HCR.0b013e3182972db7. PMID: 23748376
Prediction of bronchopulmonary dysplasia.
May C, Patel S, Kennedy C, Pollina E, Rafferty GF, Peacock JL, Greenough A
Arch Dis Child Fetal Neonatal Ed 2011 Nov;96(6):F410-6. Epub 2011 Feb 28 doi: 10.1136/adc.2010.189597. PMID: 21362700
Effect of uremia and its treatment on pulmonary function.
Prezant DJ
Lung 1990;168(1):1-14. doi: 10.1007/BF02719668. PMID: 2105408

Recent systematic reviews

The Impact of Positive Expiratory Pressure Therapy on Hyperinflation in Patients With COPD.
de Macedo JRFF, Conceiçãodos Dos Santos ED, Reychler G, Poncin W
Respir Care 2024 Feb 28;69(3):366-375. doi: 10.4187/respcare.11039. PMID: 38416659Free PMC Article

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