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Advanced Malignant Genitourinary System Neoplasm

MedGen UID:
1783465
Concept ID:
C5447477
Neoplastic Process

Definition

A malignant genitourinary neoplasm that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Malignant Genitourinary System Neoplasm

Professional guidelines

PubMed

Sekhoacha M, Riet K, Motloung P, Gumenku L, Adegoke A, Mashele S
Molecules 2022 Sep 5;27(17) doi: 10.3390/molecules27175730. PMID: 36080493Free PMC Article
Bahadoram S, Davoodi M, Hassanzadeh S, Bahadoram M, Barahman M, Mafakher L
G Ital Nefrol 2022 Jun 20;39(3) PMID: 35819037
Litwin MS, Tan HJ
JAMA 2017 Jun 27;317(24):2532-2542. doi: 10.1001/jama.2017.7248. PMID: 28655021

Recent clinical studies

Etiology

Gillessen S, Bossi A, Davis ID, de Bono J, Fizazi K, James ND, Mottet N, Shore N, Small E, Smith M, Sweeney C, Tombal B, Antonarakis ES, Aparicio AM, Armstrong AJ, Attard G, Beer TM, Beltran H, Bjartell A, Blanchard P, Briganti A, Bristow RG, Bulbul M, Caffo O, Castellano D, Castro E, Cheng HH, Chi KN, Chowdhury S, Clarke CS, Clarke N, Daugaard G, De Santis M, Duran I, Eeles R, Efstathiou E, Efstathiou J, Ngozi Ekeke O, Evans CP, Fanti S, Feng FY, Fonteyne V, Fossati N, Frydenberg M, George D, Gleave M, Gravis G, Halabi S, Heinrich D, Herrmann K, Higano C, Hofman MS, Horvath LG, Hussain M, Jereczek-Fossa BA, Jones R, Kanesvaran R, Kellokumpu-Lehtinen PL, Khauli RB, Klotz L, Kramer G, Leibowitz R, Logothetis CJ, Mahal BA, Maluf F, Mateo J, Matheson D, Mehra N, Merseburger A, Morgans AK, Morris MJ, Mrabti H, Mukherji D, Murphy DG, Murthy V, Nguyen PL, Oh WK, Ost P, O'Sullivan JM, Padhani AR, Pezaro C, Poon DMC, Pritchard CC, Rabah DM, Rathkopf D, Reiter RE, Rubin MA, Ryan CJ, Saad F, Pablo Sade J, Sartor OA, Scher HI, Sharifi N, Skoneczna I, Soule H, Spratt DE, Srinivas S, Sternberg CN, Steuber T, Suzuki H, Sydes MR, Taplin ME, Tilki D, Türkeri L, Turco F, Uemura H, Uemura H, Ürün Y, Vale CL, van Oort I, Vapiwala N, Walz J, Yamoah K, Ye D, Yu EY, Zapatero A, Zilli T, Omlin A
Eur Urol 2023 Mar;83(3):267-293. Epub 2022 Dec 6 doi: 10.1016/j.eururo.2022.11.002. PMID: 36494221Free PMC Article
Bahadoram S, Davoodi M, Hassanzadeh S, Bahadoram M, Barahman M, Mafakher L
G Ital Nefrol 2022 Jun 20;39(3) PMID: 35819037
Crosbie EJ, Kitson SJ, McAlpine JN, Mukhopadhyay A, Powell ME, Singh N
Lancet 2022 Apr 9;399(10333):1412-1428. doi: 10.1016/S0140-6736(22)00323-3. PMID: 35397864
Spreafico F, Fernandez CV, Brok J, Nakata K, Vujanic G, Geller JI, Gessler M, Maschietto M, Behjati S, Polanco A, Paintsil V, Luna-Fineman S, Pritchard-Jones K
Nat Rev Dis Primers 2021 Oct 14;7(1):75. doi: 10.1038/s41572-021-00308-8. PMID: 34650095
Teo MY, Rathkopf DE, Kantoff P
Annu Rev Med 2019 Jan 27;70:479-499. doi: 10.1146/annurev-med-051517-011947. PMID: 30691365Free PMC Article

Diagnosis

Wasim S, Lee SY, Kim J
Int J Mol Sci 2022 Nov 17;23(22) doi: 10.3390/ijms232214257. PMID: 36430730Free PMC Article
Bahadoram S, Davoodi M, Hassanzadeh S, Bahadoram M, Barahman M, Mafakher L
G Ital Nefrol 2022 Jun 20;39(3) PMID: 35819037
Crosbie EJ, Kitson SJ, McAlpine JN, Mukhopadhyay A, Powell ME, Singh N
Lancet 2022 Apr 9;399(10333):1412-1428. doi: 10.1016/S0140-6736(22)00323-3. PMID: 35397864
Teo MY, Rathkopf DE, Kantoff P
Annu Rev Med 2019 Jan 27;70:479-499. doi: 10.1146/annurev-med-051517-011947. PMID: 30691365Free PMC Article
Wang G, Zhao D, Spring DJ, DePinho RA
Genes Dev 2018 Sep 1;32(17-18):1105-1140. doi: 10.1101/gad.315739.118. PMID: 30181359Free PMC Article

Therapy

He Y, Xu W, Xiao YT, Huang H, Gu D, Ren S
Signal Transduct Target Ther 2022 Jun 24;7(1):198. doi: 10.1038/s41392-022-01042-7. PMID: 35750683Free PMC Article
Achard V, Putora PM, Omlin A, Zilli T, Fischer S
Oncology 2022;100(1):48-59. Epub 2021 Nov 15 doi: 10.1159/000519861. PMID: 34781285
How JA, Patel A, Jazaeri AA
Adv Exp Med Biol 2021;1342:193-232. doi: 10.1007/978-3-030-79308-1_6. PMID: 34972966
Attademo L, Tuninetti V, Pisano C, Cecere SC, Di Napoli M, Tambaro R, Valabrega G, Musacchio L, Setola SV, Piccirillo P, Califano D, Spina A, Losito S, Greggi S, Pignata S
Cancer Treat Rev 2020 Nov;90:102088. Epub 2020 Aug 7 doi: 10.1016/j.ctrv.2020.102088. PMID: 32827839
Mayadev J, Nunes AT, Li M, Marcovitz M, Lanasa MC, Monk BJ
Int J Gynecol Cancer 2020 Jul;30(7):1065-1070. Epub 2020 May 23 doi: 10.1136/ijgc-2019-001135. PMID: 32447296Free PMC Article

Prognosis

Siegel RL, Miller KD, Fuchs HE, Jemal A
CA Cancer J Clin 2022 Jan;72(1):7-33. Epub 2022 Jan 12 doi: 10.3322/caac.21708. PMID: 35020204
O'Malley DM, Bariani GM, Cassier PA, Marabelle A, Hansen AR, De Jesus Acosta A, Miller WH Jr, Safra T, Italiano A, Mileshkin L, Xu L, Jin F, Norwood K, Maio M
J Clin Oncol 2022 Mar 1;40(7):752-761. Epub 2022 Jan 6 doi: 10.1200/JCO.21.01874. PMID: 34990208Free PMC Article
Guo M, Xu J, Du J
BMC Public Health 2021 Jul 6;21(1):1329. doi: 10.1186/s12889-021-11401-8. PMID: 34229639Free PMC Article
McDermott DF, Lee JL, Ziobro M, Suarez C, Langiewicz P, Matveev VB, Wiechno P, Gafanov RA, Tomczak P, Pouliot F, Donskov F, Alekseev BY, Shin SJ, Bjarnason GA, Castellano D, Silverman RK, Perini RF, Schloss C, Atkins MB
J Clin Oncol 2021 Mar 20;39(9):1029-1039. Epub 2021 Feb 2 doi: 10.1200/JCO.20.02365. PMID: 33529058Free PMC Article
Moore DH
Obstet Gynecol 2006 May;107(5):1152-61. doi: 10.1097/01.AOG.0000215986.48590.79. PMID: 16648423

Clinical prediction guides

Koti M, Bivalacqua T, Black PC, Cathomen T, Galsky MD, Gulley JL, Ingersoll MA, Kamat AM, Kassouf W, Siemens DR, Gao J
Eur Urol Oncol 2023 Jun;6(3):263-272. Epub 2023 Apr 15 doi: 10.1016/j.euo.2023.03.002. PMID: 37069029
Xiao Y, Shan ZJ, Yang JF, Len JJ, Yu YH, Yang ML
Urol Oncol 2023 Jan;41(1):15-26. Epub 2022 Jul 28 doi: 10.1016/j.urolonc.2022.06.019. PMID: 35907706
Jones RT, Felsenstein KM, Theodorescu D
Urol Clin North Am 2016 Feb;43(1):77-86. Epub 2015 Oct 31 doi: 10.1016/j.ucl.2015.08.007. PMID: 26614030Free PMC Article
Cowan NC, Crew JP
Curr Opin Urol 2010 Sep;20(5):409-13. doi: 10.1097/MOU.0b013e32833cbcb9. PMID: 20625298
Fagotti A, Ferrandina G, Fanfani F, Ercoli A, Lorusso D, Rossi M, Scambia G
Ann Surg Oncol 2006 Aug;13(8):1156-61. Epub 2006 Jun 21 doi: 10.1245/ASO.2006.08.021. PMID: 16791447

Recent systematic reviews

Bukavina L, Bensalah K, Bray F, Carlo M, Challacombe B, Karam JA, Kassouf W, Mitchell T, Montironi R, O'Brien T, Panebianco V, Scelo G, Shuch B, van Poppel H, Blosser CD, Psutka SP
Eur Urol 2022 Nov;82(5):529-542. Epub 2022 Sep 10 doi: 10.1016/j.eururo.2022.08.019. PMID: 36100483
Xu Y, Jia Y, Zhang Q, Du Y, He Y, Zheng A
Gynecol Oncol 2021 Feb;160(2):610-618. Epub 2020 Nov 19 doi: 10.1016/j.ygyno.2020.11.010. PMID: 33221022
Vale CL, Fisher D, Kneebone A, Parker C, Pearse M, Richaud P, Sargos P, Sydes MR, Brawley C, Brihoum M, Brown C, Chabaud S, Cook A, Forcat S, Fraser-Browne C, Latorzeff I, Parmar MKB, Tierney JF; ARTISTIC Meta-analysis Group
Lancet 2020 Oct 31;396(10260):1422-1431. Epub 2020 Sep 28 doi: 10.1016/S0140-6736(20)31952-8. PMID: 33002431Free PMC Article
Applegate CC, Rowles JL, Ranard KM, Jeon S, Erdman JW
Nutrients 2018 Jan 4;10(1) doi: 10.3390/nu10010040. PMID: 29300347Free PMC Article
Peirson L, Fitzpatrick-Lewis D, Ciliska D, Warren R
Syst Rev 2013 May 24;2:35. doi: 10.1186/2046-4053-2-35. PMID: 23706117Free PMC Article

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