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Inverse Marcus-Gunn phenomenon

MedGen UID:
Concept ID:
Disease or Syndrome
Synonym: inverse Marcus-Gunn phenomenon
SNOMED CT: Inverse Marcus-Gunn phenomenon (1156827007)
Monarch Initiative: MONDO:0020362
Orphanet: ORPHA98951


Inverse Marcus-Gunn phenomenon is a rare congenital synkinesis where jaw opening by the pterygoid muscle (during eating or yawning) causes eyelid drooping from inhibition of the oculomotor nerve to the levator palpebrae superioris. Familial occurrence has been reported. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInverse Marcus-Gunn phenomenon

Recent clinical studies


Pavone P, Garozzo R, Trifiletti RR, Parano E
J Child Neurol 1999 Apr;14(4):266-8. doi: 10.1177/088307389901400411. PMID: 10334404


Myers KA, Innes AM, Mah JK
Pediatrics 2016 Dec;138(6) Epub 2016 Nov 17 doi: 10.1542/peds.2016-1724. PMID: 27940697
Rana PV, Wadia RS
J Neurol Neurosurg Psychiatry 1985 Sep;48(9):939-41. doi: 10.1136/jnnp.48.9.939. PMID: 4045488Free PMC Article

Clinical prediction guides

Lubkin V
Arch Neurol 1978 Apr;35(4):249. doi: 10.1001/archneur.1978.00500280067015. PMID: 637763

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