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Decreased left ventricular end-diastolic volume

MedGen UID:
1784775
•Concept ID:
C5539796
•
Finding
HPO: HP:0033756

Definition

Abnormally low volume of blood in the left ventricle at the end of diastole (just before systole). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased left ventricular end-diastolic volume

Professional guidelines

PubMed

ESC/EACTS vs. ACC/AHA guidelines for the management of severe aortic stenosis.
Lee G, Chikwe J, Milojevic M, Wijeysundera HC, Biondi-Zoccai G, Flather M, Gaudino MFL, Fremes SE, Tam DY
Eur Heart J 2023 Mar 7;44(10):796-812. doi: 10.1093/eurheartj/ehac803. PMID: 36632841
Heart failure with preserved ejection fraction: recent concepts in diagnosis, mechanisms and management.
Gevaert AB, Kataria R, Zannad F, Sauer AJ, Damman K, Sharma K, Shah SJ, Van Spall HGC
Heart 2022 Aug 11;108(17):1342-1350. doi: 10.1136/heartjnl-2021-319605. PMID: 35022210
Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology.
Harjola VP, Mebazaa A, Čelutkienė J, Bettex D, Bueno H, Chioncel O, Crespo-Leiro MG, Falk V, Filippatos G, Gibbs S, Leite-Moreira A, Lassus J, Masip J, Mueller C, Mullens W, Naeije R, Nordegraaf AV, Parissis J, Riley JP, Ristic A, Rosano G, Rudiger A, Ruschitzka F, Seferovic P, Sztrymf B, Vieillard-Baron A, Yilmaz MB, Konstantinides S
Eur J Heart Fail 2016 Mar;18(3):226-41. doi: 10.1002/ejhf.478. PMID: 26995592

Recent clinical studies

Etiology

Absence of left ventricular volume loading in infants with coarctation of the aorta and a large ventricular septal defect.
Graham TP Jr, Burger J, Boucek RJ Jr, Johns JA, Moreau GA, Hammon JW Jr, Bender HW Jr
J Am Coll Cardiol 1989 Nov 15;14(6):1545-52. doi: 10.1016/0735-1097(89)90396-3. PMID: 2530263

Diagnosis

Demasking of subclinical left ventricular dysfunction in anemic children.
Kapoor RK, Singh L, Mehrotra S, Mishra PK, Chandra M
Indian Pediatr 1999 Oct;36(10):991-8. PMID: 10745309
Left ventricular function assessed with echocardiography and myocardial perfusion assessed with scintigraphy under dipyridamole stress in pediatric patients after repair for anomalous origin of the left coronary artery from the pulmonary artery.
Stern H, Sauer U, Locher D, Bauer R, Meisner H, Sebening F, Bühlmeyer K
J Thorac Cardiovasc Surg 1993 Oct;106(4):723-32. PMID: 8412269

Therapy

Predicted Cardiac Hemodynamic Consequences of the Renal Actions of SGLT2i in the DAPA-HF Study Population: A Mathematical Modeling Analysis.
Yu H, Tang W, Greasley PJ, Penland RC, Boulton DW, Hallow KM
J Clin Pharmacol 2021 May;61(5):636-648. Epub 2020 Oct 22 doi: 10.1002/jcph.1769. PMID: 33091173
Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression.
Morelli A, De Castro S, Teboul JL, Singer M, Rocco M, Conti G, De Luca L, Di Angelantonio E, Orecchioni A, Pandian NG, Pietropaoli P
Intensive Care Med 2005 May;31(5):638-44. Epub 2005 Apr 6 doi: 10.1007/s00134-005-2619-z. PMID: 15812624
Comparative effects of verapamil and nitroprusside on left ventricular function in patients with hypertension.
Brush JE Jr, Udelson JE, Bacharach SL, Cannon RO 3rd, Leon MB, Rumble TF, Bonow RO
J Am Coll Cardiol 1989 Aug;14(2):515-22. doi: 10.1016/0735-1097(89)90210-6. PMID: 2754137

Prognosis

Predicted Cardiac Hemodynamic Consequences of the Renal Actions of SGLT2i in the DAPA-HF Study Population: A Mathematical Modeling Analysis.
Yu H, Tang W, Greasley PJ, Penland RC, Boulton DW, Hallow KM
J Clin Pharmacol 2021 May;61(5):636-648. Epub 2020 Oct 22 doi: 10.1002/jcph.1769. PMID: 33091173
Left ventricular function assessed with echocardiography and myocardial perfusion assessed with scintigraphy under dipyridamole stress in pediatric patients after repair for anomalous origin of the left coronary artery from the pulmonary artery.
Stern H, Sauer U, Locher D, Bauer R, Meisner H, Sebening F, Bühlmeyer K
J Thorac Cardiovasc Surg 1993 Oct;106(4):723-32. PMID: 8412269
Absence of left ventricular volume loading in infants with coarctation of the aorta and a large ventricular septal defect.
Graham TP Jr, Burger J, Boucek RJ Jr, Johns JA, Moreau GA, Hammon JW Jr, Bender HW Jr
J Am Coll Cardiol 1989 Nov 15;14(6):1545-52. doi: 10.1016/0735-1097(89)90396-3. PMID: 2530263

Clinical prediction guides

Predicted Cardiac Hemodynamic Consequences of the Renal Actions of SGLT2i in the DAPA-HF Study Population: A Mathematical Modeling Analysis.
Yu H, Tang W, Greasley PJ, Penland RC, Boulton DW, Hallow KM
J Clin Pharmacol 2021 May;61(5):636-648. Epub 2020 Oct 22 doi: 10.1002/jcph.1769. PMID: 33091173
Demasking of subclinical left ventricular dysfunction in anemic children.
Kapoor RK, Singh L, Mehrotra S, Mishra PK, Chandra M
Indian Pediatr 1999 Oct;36(10):991-8. PMID: 10745309
Left ventricular function assessed with echocardiography and myocardial perfusion assessed with scintigraphy under dipyridamole stress in pediatric patients after repair for anomalous origin of the left coronary artery from the pulmonary artery.
Stern H, Sauer U, Locher D, Bauer R, Meisner H, Sebening F, Bühlmeyer K
J Thorac Cardiovasc Surg 1993 Oct;106(4):723-32. PMID: 8412269
Absence of left ventricular volume loading in infants with coarctation of the aorta and a large ventricular septal defect.
Graham TP Jr, Burger J, Boucek RJ Jr, Johns JA, Moreau GA, Hammon JW Jr, Bender HW Jr
J Am Coll Cardiol 1989 Nov 15;14(6):1545-52. doi: 10.1016/0735-1097(89)90396-3. PMID: 2530263

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