U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Elevated myocardial native T1

MedGen UID:
1785178
Concept ID:
C5539858
Finding
Synonym: Prolonged myocardial native T1
 
HPO: HP:4000006

Definition

Increased duration of myocardial T1 time without gadolinium contrast. T1 mapping consists of quantifying the T1 relaxation time of a tissue by using analytical expressions of image-based signal intensities. A fundamental principle of MR imaging is that the signal intensity of pixels is based on the relaxation of hydrogen nuclei protons in a static magnetic field. The T1 relaxation times between two tissues vary substantially. Edema, fat infiltration, and fibrosis also cause differences in T1 relaxivity. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Haslbauer JD, Lindner S, Valbuena-Lopez S, Zainal H, Zhou H, D'Angelo T, Pathan F, Arendt CA, Bug G, Serve H, Vogl TJ, Zeiher AM, Carr-White G, Nagel E, Puntmann VO
Int J Cardiol 2019 Jan 15;275:179-186. Epub 2018 Oct 11 doi: 10.1016/j.ijcard.2018.10.023. PMID: 30360992

Recent clinical studies

Etiology

Chehab O, Abdollahi A, Whelton SP, Wu CO, Ambale-Venkatesh B, Post WS, Bluemke DA, Tsai MY, Lima JAC
J Am Coll Cardiol 2023 Dec 12;82(24):2280-2291. doi: 10.1016/j.jacc.2023.10.016. PMID: 38057070
Thavendiranathan P, Shalmon T, Fan CS, Houbois C, Amir E, Thevakumaran Y, Somerset E, Malowany JM, Urzua-Fresno C, Yip P, McIntosh C, Sussman MS, Brezden-Masley C, Yan AT, Koch CA, Spiller N, Abdel-Qadir H, Power C, Hanneman K, Wintersperger BJ
JAMA Cardiol 2023 Jun 1;8(6):524-534. doi: 10.1001/jamacardio.2023.0494. PMID: 37043251Free PMC Article
Buck B, Chum AP, Patel M, Carter R, Nawaz H, Yildiz V, Ruz P, Wiczer T, Rogers KA, Awan FT, Bhat S, Guha A, Kittai AS, Simonetti OP, Raman SV, Wallace G, Sanchez R, Bonsu JM, Gambril J, Haddad D, Mann J, Wei L, Kola-Kehinde O, Byrd JC, Woyach JA, Addison D
JAMA Oncol 2023 Apr 1;9(4):552-555. doi: 10.1001/jamaoncol.2022.6869. PMID: 36729480Free PMC Article
Puntmann VO, Carerj ML, Wieters I, Fahim M, Arendt C, Hoffmann J, Shchendrygina A, Escher F, Vasa-Nicotera M, Zeiher AM, Vehreschild M, Nagel E
JAMA Cardiol 2020 Nov 1;5(11):1265-1273. doi: 10.1001/jamacardio.2020.3557. PMID: 32730619Free PMC Article
Huang L, Ran L, Zhao P, Tang D, Han R, Ai T, Xia L, Tao Q
Br J Radiol 2019 Dec;92(1104):20190634. Epub 2019 Oct 16 doi: 10.1259/bjr.20190634. PMID: 31613647Free PMC Article

Diagnosis

Chehab O, Abdollahi A, Whelton SP, Wu CO, Ambale-Venkatesh B, Post WS, Bluemke DA, Tsai MY, Lima JAC
J Am Coll Cardiol 2023 Dec 12;82(24):2280-2291. doi: 10.1016/j.jacc.2023.10.016. PMID: 38057070
Thavendiranathan P, Shalmon T, Fan CS, Houbois C, Amir E, Thevakumaran Y, Somerset E, Malowany JM, Urzua-Fresno C, Yip P, McIntosh C, Sussman MS, Brezden-Masley C, Yan AT, Koch CA, Spiller N, Abdel-Qadir H, Power C, Hanneman K, Wintersperger BJ
JAMA Cardiol 2023 Jun 1;8(6):524-534. doi: 10.1001/jamacardio.2023.0494. PMID: 37043251Free PMC Article
Buck B, Chum AP, Patel M, Carter R, Nawaz H, Yildiz V, Ruz P, Wiczer T, Rogers KA, Awan FT, Bhat S, Guha A, Kittai AS, Simonetti OP, Raman SV, Wallace G, Sanchez R, Bonsu JM, Gambril J, Haddad D, Mann J, Wei L, Kola-Kehinde O, Byrd JC, Woyach JA, Addison D
JAMA Oncol 2023 Apr 1;9(4):552-555. doi: 10.1001/jamaoncol.2022.6869. PMID: 36729480Free PMC Article
Puntmann VO, Carerj ML, Wieters I, Fahim M, Arendt C, Hoffmann J, Shchendrygina A, Escher F, Vasa-Nicotera M, Zeiher AM, Vehreschild M, Nagel E
JAMA Cardiol 2020 Nov 1;5(11):1265-1273. doi: 10.1001/jamacardio.2020.3557. PMID: 32730619Free PMC Article
Huang L, Ran L, Zhao P, Tang D, Han R, Ai T, Xia L, Tao Q
Br J Radiol 2019 Dec;92(1104):20190634. Epub 2019 Oct 16 doi: 10.1259/bjr.20190634. PMID: 31613647Free PMC Article

Therapy

Sunthankar SD, George-Durrett K, Crum K, Slaughter JC, Kasten J, Raucci FJ Jr, Markham LW, Soslow JH
J Cardiovasc Magn Reson 2023 Jul 31;25(1):44. doi: 10.1186/s12968-023-00951-y. PMID: 37517994Free PMC Article
Thavendiranathan P, Shalmon T, Fan CS, Houbois C, Amir E, Thevakumaran Y, Somerset E, Malowany JM, Urzua-Fresno C, Yip P, McIntosh C, Sussman MS, Brezden-Masley C, Yan AT, Koch CA, Spiller N, Abdel-Qadir H, Power C, Hanneman K, Wintersperger BJ
JAMA Cardiol 2023 Jun 1;8(6):524-534. doi: 10.1001/jamacardio.2023.0494. PMID: 37043251Free PMC Article
Thavendiranathan P, Zhang L, Zafar A, Drobni ZD, Mahmood SS, Cabral M, Awadalla M, Nohria A, Zlotoff DA, Thuny F, Heinzerling LM, Barac A, Sullivan RJ, Chen CL, Gupta D, Kirchberger MC, Hartmann SE, Weinsaft JW, Gilman HK, Rizvi MA, Kovacina B, Michel C, Sahni G, González-Mansilla A, Calles A, Fernández-Avilés F, Mahmoudi M, Reynolds KL, Ganatra S, Gavira JJ, González NS, García de Yébenes Castro M, Kwong RY, Jerosch-Herold M, Coelho-Filho OR, Afilalo J, Zataraín-Nicolás E, Baksi AJ, Wintersperger BJ, Calvillo-Arguelles O, Ederhy S, Yang EH, Lyon AR, Fradley MG, Neilan TG
J Am Coll Cardiol 2021 Mar 30;77(12):1503-1516. doi: 10.1016/j.jacc.2021.01.050. PMID: 33766256Free PMC Article
Mawad W, Mertens L, Pagano JJ, Riesenkampff E, Reichert MJE, Mital S, Kantor PF, Greenberg M, Liu P, Nathan PC, Grosse-Wortmann L
Eur Heart J Cardiovasc Imaging 2021 Mar 22;22(4):435-442. doi: 10.1093/ehjci/jeaa093. PMID: 32535624Free PMC Article
Puntmann VO, Carerj ML, Wieters I, Fahim M, Arendt C, Hoffmann J, Shchendrygina A, Escher F, Vasa-Nicotera M, Zeiher AM, Vehreschild M, Nagel E
JAMA Cardiol 2020 Nov 1;5(11):1265-1273. doi: 10.1001/jamacardio.2020.3557. PMID: 32730619Free PMC Article

Prognosis

Chehab O, Abdollahi A, Whelton SP, Wu CO, Ambale-Venkatesh B, Post WS, Bluemke DA, Tsai MY, Lima JAC
J Am Coll Cardiol 2023 Dec 12;82(24):2280-2291. doi: 10.1016/j.jacc.2023.10.016. PMID: 38057070
Yue P, Xu Z, Wan K, Tan Y, Xu Y, Xie X, Mui D, Yi C, Han Y, Chen Y
J Cardiovasc Magn Reson 2023 Jun 22;25(1):37. doi: 10.1186/s12968-023-00938-9. PMID: 37349765Free PMC Article
Buck B, Chum AP, Patel M, Carter R, Nawaz H, Yildiz V, Ruz P, Wiczer T, Rogers KA, Awan FT, Bhat S, Guha A, Kittai AS, Simonetti OP, Raman SV, Wallace G, Sanchez R, Bonsu JM, Gambril J, Haddad D, Mann J, Wei L, Kola-Kehinde O, Byrd JC, Woyach JA, Addison D
JAMA Oncol 2023 Apr 1;9(4):552-555. doi: 10.1001/jamaoncol.2022.6869. PMID: 36729480Free PMC Article
Puntmann VO, Carerj ML, Wieters I, Fahim M, Arendt C, Hoffmann J, Shchendrygina A, Escher F, Vasa-Nicotera M, Zeiher AM, Vehreschild M, Nagel E
JAMA Cardiol 2020 Nov 1;5(11):1265-1273. doi: 10.1001/jamacardio.2020.3557. PMID: 32730619Free PMC Article
Martinez-Naharro A, Kotecha T, Norrington K, Boldrini M, Rezk T, Quarta C, Treibel TA, Whelan CJ, Knight DS, Kellman P, Ruberg FL, Gillmore JD, Moon JC, Hawkins PN, Fontana M
JACC Cardiovasc Imaging 2019 May;12(5):810-819. Epub 2018 Mar 14 doi: 10.1016/j.jcmg.2018.02.006. PMID: 29550324

Clinical prediction guides

Chehab O, Abdollahi A, Whelton SP, Wu CO, Ambale-Venkatesh B, Post WS, Bluemke DA, Tsai MY, Lima JAC
J Am Coll Cardiol 2023 Dec 12;82(24):2280-2291. doi: 10.1016/j.jacc.2023.10.016. PMID: 38057070
Thavendiranathan P, Shalmon T, Fan CS, Houbois C, Amir E, Thevakumaran Y, Somerset E, Malowany JM, Urzua-Fresno C, Yip P, McIntosh C, Sussman MS, Brezden-Masley C, Yan AT, Koch CA, Spiller N, Abdel-Qadir H, Power C, Hanneman K, Wintersperger BJ
JAMA Cardiol 2023 Jun 1;8(6):524-534. doi: 10.1001/jamacardio.2023.0494. PMID: 37043251Free PMC Article
Buck B, Chum AP, Patel M, Carter R, Nawaz H, Yildiz V, Ruz P, Wiczer T, Rogers KA, Awan FT, Bhat S, Guha A, Kittai AS, Simonetti OP, Raman SV, Wallace G, Sanchez R, Bonsu JM, Gambril J, Haddad D, Mann J, Wei L, Kola-Kehinde O, Byrd JC, Woyach JA, Addison D
JAMA Oncol 2023 Apr 1;9(4):552-555. doi: 10.1001/jamaoncol.2022.6869. PMID: 36729480Free PMC Article
Puntmann VO, Carerj ML, Wieters I, Fahim M, Arendt C, Hoffmann J, Shchendrygina A, Escher F, Vasa-Nicotera M, Zeiher AM, Vehreschild M, Nagel E
JAMA Cardiol 2020 Nov 1;5(11):1265-1273. doi: 10.1001/jamacardio.2020.3557. PMID: 32730619Free PMC Article
Martinez-Naharro A, Kotecha T, Norrington K, Boldrini M, Rezk T, Quarta C, Treibel TA, Whelan CJ, Knight DS, Kellman P, Ruberg FL, Gillmore JD, Moon JC, Hawkins PN, Fontana M
JACC Cardiovasc Imaging 2019 May;12(5):810-819. Epub 2018 Mar 14 doi: 10.1016/j.jcmg.2018.02.006. PMID: 29550324

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...