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Abnormal urine metabolite level

MedGen UID:
1785188
Concept ID:
C5539535
Finding
HPO: HP:0033354

Definition

Any deviation from the normal amount of a metabolite in urine. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal urine metabolite level

Professional guidelines

PubMed

Stockler S, Schutz PW, Salomons GS
Subcell Biochem 2007;46:149-66. doi: 10.1007/978-1-4020-6486-9_8. PMID: 18652076
Hughes IA, Arisaka O, Perry LA, Honour JW
Acta Endocrinol (Copenh) 1986 Mar;111(3):349-54. doi: 10.1530/acta.0.1110349. PMID: 3515819
Correa de Oliveira RF, Novaes LP, Lima MB, Rodrigues J, Franco S, Khenaifes AI, Francalanci CP
Ann Intern Med 1975 Dec;83(6):817-9. doi: 10.7326/0003-4819-83-6-817. PMID: 1200527

Recent clinical studies

Etiology

Li Y, Wang X, Zhu Q, Xu Y, Fu Q, Wang T, Liao C, Jiang G
Environ Sci Technol 2023 May 9;57(18):7109-7128. Epub 2023 Apr 20 doi: 10.1021/acs.est.2c06503. PMID: 37079500
Ji J, Song L, Wang J, Yang Z, Yan H, Li T, Yu L, Jian L, Jiang F, Li J, Zheng J, Li K
Environ Int 2021 Aug;153:106524. Epub 2021 Mar 19 doi: 10.1016/j.envint.2021.106524. PMID: 33773143Free PMC Article
Fratrić I, Varga J, Vukmirović S, Sudji J, Živković D
J Pediatr Surg 2017 Jul;52(7):1166-1168. Epub 2016 Dec 7 doi: 10.1016/j.jpedsurg.2016.11.048. PMID: 27956069
Zhang C, Yin A, Li H, Wang R, Wu G, Shen J, Zhang M, Wang L, Hou Y, Ouyang H, Zhang Y, Zheng Y, Wang J, Lv X, Wang Y, Zhang F, Zeng B, Li W, Yan F, Zhao Y, Pang X, Zhang X, Fu H, Chen F, Zhao N, Hamaker BR, Bridgewater LC, Weinkove D, Clement K, Dore J, Holmes E, Xiao H, Zhao G, Yang S, Bork P, Nicholson JK, Wei H, Tang H, Zhang X, Zhao L
EBioMedicine 2015 Aug;2(8):968-84. Epub 2015 Jul 10 doi: 10.1016/j.ebiom.2015.07.007. PMID: 26425705Free PMC Article
Wilson RG, Davis RE
Adv Clin Chem 1983;23:1-68. doi: 10.1016/s0065-2423(08)60397-2. PMID: 6398613

Diagnosis

Kim Y, Lee J, Kang MS, Song J, Kim SG, Cho S, Huh H, Lee S, Park S, Jo HA, Yang SH, Paek JH, Park WY, Han SS, Lee H, Lee JP, Joo KW, Lim CS, Hwang GS, Kim DK
Kidney360 2023 Aug 1;4(8):1048-1057. Epub 2023 Jun 9 doi: 10.34067/KID.0000000000000158. PMID: 37291728Free PMC Article
Morava E, Oglesbee D
Handb Clin Neurol 2023;194:167-172. doi: 10.1016/B978-0-12-821751-1.00012-9. PMID: 36813311
Funder JW
J Steroid Biochem Mol Biol 2017 Jan;165(Pt A):151-153. Epub 2016 Mar 5 doi: 10.1016/j.jsbmb.2016.03.010. PMID: 26956190
Sprott H, Müller A, Heine H
Arthritis Rheum 1997 Aug;40(8):1450-4. doi: 10.1002/art.1780400813. PMID: 9259425
Funder JW
Endocrinol Metab Clin North Am 1995 Sep;24(3):613-21. PMID: 8575412

Therapy

Christov M, Neyra JA, Gupta S, Leaf DE
Semin Nephrol 2019 Jan;39(1):57-75. doi: 10.1016/j.semnephrol.2018.10.005. PMID: 30606408
Fratrić I, Varga J, Vukmirović S, Sudji J, Živković D
J Pediatr Surg 2017 Jul;52(7):1166-1168. Epub 2016 Dec 7 doi: 10.1016/j.jpedsurg.2016.11.048. PMID: 27956069
Zhang C, Yin A, Li H, Wang R, Wu G, Shen J, Zhang M, Wang L, Hou Y, Ouyang H, Zhang Y, Zheng Y, Wang J, Lv X, Wang Y, Zhang F, Zeng B, Li W, Yan F, Zhao Y, Pang X, Zhang X, Fu H, Chen F, Zhao N, Hamaker BR, Bridgewater LC, Weinkove D, Clement K, Dore J, Holmes E, Xiao H, Zhao G, Yang S, Bork P, Nicholson JK, Wei H, Tang H, Zhang X, Zhao L
EBioMedicine 2015 Aug;2(8):968-84. Epub 2015 Jul 10 doi: 10.1016/j.ebiom.2015.07.007. PMID: 26425705Free PMC Article
Kennedy GL Jr
Crit Rev Toxicol 1986;17(2):129-82. doi: 10.3109/10408448609023768. PMID: 3530639
Wilson RG, Davis RE
Adv Clin Chem 1983;23:1-68. doi: 10.1016/s0065-2423(08)60397-2. PMID: 6398613

Prognosis

Kim Y, Lee J, Kang MS, Song J, Kim SG, Cho S, Huh H, Lee S, Park S, Jo HA, Yang SH, Paek JH, Park WY, Han SS, Lee H, Lee JP, Joo KW, Lim CS, Hwang GS, Kim DK
Kidney360 2023 Aug 1;4(8):1048-1057. Epub 2023 Jun 9 doi: 10.34067/KID.0000000000000158. PMID: 37291728Free PMC Article
Li Y, Wang X, Zhu Q, Xu Y, Fu Q, Wang T, Liao C, Jiang G
Environ Sci Technol 2023 May 9;57(18):7109-7128. Epub 2023 Apr 20 doi: 10.1021/acs.est.2c06503. PMID: 37079500
Hipperson L, Hadden WJ, Nahm CB, Gill AJ, Samra JS, Dona A, Mittal A, Sahni S
Biochim Biophys Acta Gen Subj 2021 Nov;1865(11):129966. Epub 2021 Jul 27 doi: 10.1016/j.bbagen.2021.129966. PMID: 34329704
Christov M, Neyra JA, Gupta S, Leaf DE
Semin Nephrol 2019 Jan;39(1):57-75. doi: 10.1016/j.semnephrol.2018.10.005. PMID: 30606408
Fratrić I, Varga J, Vukmirović S, Sudji J, Živković D
J Pediatr Surg 2017 Jul;52(7):1166-1168. Epub 2016 Dec 7 doi: 10.1016/j.jpedsurg.2016.11.048. PMID: 27956069

Clinical prediction guides

Kim Y, Lee J, Kang MS, Song J, Kim SG, Cho S, Huh H, Lee S, Park S, Jo HA, Yang SH, Paek JH, Park WY, Han SS, Lee H, Lee JP, Joo KW, Lim CS, Hwang GS, Kim DK
Kidney360 2023 Aug 1;4(8):1048-1057. Epub 2023 Jun 9 doi: 10.34067/KID.0000000000000158. PMID: 37291728Free PMC Article
Li Y, Wang X, Zhu Q, Xu Y, Fu Q, Wang T, Liao C, Jiang G
Environ Sci Technol 2023 May 9;57(18):7109-7128. Epub 2023 Apr 20 doi: 10.1021/acs.est.2c06503. PMID: 37079500
Morava E, Oglesbee D
Handb Clin Neurol 2023;194:167-172. doi: 10.1016/B978-0-12-821751-1.00012-9. PMID: 36813311
Christov M, Neyra JA, Gupta S, Leaf DE
Semin Nephrol 2019 Jan;39(1):57-75. doi: 10.1016/j.semnephrol.2018.10.005. PMID: 30606408
Wilson RG, Davis RE
Adv Clin Chem 1983;23:1-68. doi: 10.1016/s0065-2423(08)60397-2. PMID: 6398613

Recent systematic reviews

De Spiegeleer M, De Paepe E, Van Meulebroek L, Gies I, De Schepper J, Vanhaecke L
Mol Med 2021 Nov 6;27(1):145. doi: 10.1186/s10020-021-00394-0. PMID: 34742239Free PMC Article
Gao H, Zhang C, Tao FB
Environ Sci Pollut Res Int 2021 May;28(17):20921-20938. Epub 2021 Mar 5 doi: 10.1007/s11356-021-13120-4. PMID: 33674970
Gallagher K, Catesson A, Griffin JL, Holmes E, Williams HRT
J Crohns Colitis 2021 May 4;15(5):813-826. doi: 10.1093/ecco-jcc/jjaa227. PMID: 33175138

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