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Breast Florid Lobular Carcinoma In Situ

MedGen UID:
1785316
Concept ID:
C5446878
Neoplastic Process

Definition

Breast lobular carcinoma in situ characterized by the presence of neoplastic cells with cytological features identical to classic lobular carcinoma in situ, but with marked distention of terminal ductal lobular units or ducts. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast Florid Lobular Carcinoma In Situ

Professional guidelines

PubMed

Sokolova A, Lakhani SR
Mod Pathol 2021 Jan;34(Suppl 1):8-14. Epub 2020 Oct 6 doi: 10.1038/s41379-020-00689-3. PMID: 33024303
Calle C, Kuba MG, Brogi E
Breast J 2020 Jun;26(6):1148-1155. Epub 2020 Jun 4 doi: 10.1111/tbj.13857. PMID: 32500575
Ginter PS, D'Alfonso TM
Arch Pathol Lab Med 2017 Dec;141(12):1668-1678. Epub 2017 Jun 2 doi: 10.5858/arpa.2016-0421-RA. PMID: 28574280

Recent clinical studies

Etiology

Heller SL, Gao Y
Radiographics 2023 Oct;43(10):e220188. doi: 10.1148/rg.220188. PMID: 37676825
Kuba MG, Murray MP, Coffey K, Calle C, Morrow M, Brogi E
Mod Pathol 2021 Aug;34(8):1495-1506. Epub 2021 Apr 6 doi: 10.1038/s41379-021-00796-9. PMID: 33824462Free PMC Article
Sokolova A, Lakhani SR
Mod Pathol 2021 Jan;34(Suppl 1):8-14. Epub 2020 Oct 6 doi: 10.1038/s41379-020-00689-3. PMID: 33024303
Ginter PS, D'Alfonso TM
Arch Pathol Lab Med 2017 Dec;141(12):1668-1678. Epub 2017 Jun 2 doi: 10.5858/arpa.2016-0421-RA. PMID: 28574280
Visscher DW, Yasir S
Endocr Pathol 2017 Jun;28(2):121-127. doi: 10.1007/s12022-017-9477-4. PMID: 28389994

Diagnosis

Heller SL, Gao Y
Radiographics 2023 Oct;43(10):e220188. doi: 10.1148/rg.220188. PMID: 37676825
Sokolova A, Lakhani SR
Mod Pathol 2021 Jan;34(Suppl 1):8-14. Epub 2020 Oct 6 doi: 10.1038/s41379-020-00689-3. PMID: 33024303
Foschini MP, Miglio R, Fiore R, Baldovini C, Castellano I, Callagy G, Bianchi S, Kaya H, Amendoeira I, Querzoli P, Poli F, Scatena C, Cordoba A, Pietribiasi F, Kovács A, Faistova H, Cserni G, Quinn C
Eur J Surg Oncol 2019 Dec;45(12):2279-2286. Epub 2019 Jul 5 doi: 10.1016/j.ejso.2019.07.011. PMID: 31301938
Ginter PS, D'Alfonso TM
Arch Pathol Lab Med 2017 Dec;141(12):1668-1678. Epub 2017 Jun 2 doi: 10.5858/arpa.2016-0421-RA. PMID: 28574280
Cheng E, D'Alfonso TM, Arafah M, Marrero Rolon R, Ginter PS, Hoda SA
Int J Surg Pathol 2017 Feb;25(1):4-11. Epub 2016 Nov 10 doi: 10.1177/1066896916677288. PMID: 27831531

Therapy

Rajesh L, Dey P, Joshi K
Anal Quant Cytol Histol 2002 Apr;24(2):81-4. PMID: 12026054
Waldo ED, Sidhu GS, Hu AW
Arch Pathol 1975 Jul;99(7):364-6. PMID: 167700

Prognosis

Brogi E
Virchows Arch 2022 Dec;481(6):823-837. Epub 2022 May 14 doi: 10.1007/s00428-022-03299-3. PMID: 35567633
Zhong E, Solomon JP, Cheng E, Baum J, Song W, Hoda SA
Am J Surg Pathol 2020 Aug;44(8):1092-1103. doi: 10.1097/PAS.0000000000001493. PMID: 32317606
Zhong E, Cheng E, Goldfischer M, Hoda SA
Am J Surg Pathol 2020 Jan;44(1):68-76. doi: 10.1097/PAS.0000000000001340. PMID: 31403965
Singh K, Paquette C, Kalife ET, Wang Y, Mangray S, Quddus MR, Steinhoff MM
Hum Pathol 2018 Aug;78:163-170. Epub 2018 May 9 doi: 10.1016/j.humpath.2018.04.026. PMID: 29753007
Visscher DW, Yasir S
Endocr Pathol 2017 Jun;28(2):121-127. doi: 10.1007/s12022-017-9477-4. PMID: 28389994

Clinical prediction guides

Jani C, Lotz M, Keates S, Gupta Y, Walker A, Al Omari O, Parvez A, Patel D, Gnata M, Perry J, Khorashadi L, Weissmann L, Pories SE
Breast J 2023;2023:8185446. Epub 2023 Apr 18 doi: 10.1155/2023/8185446. PMID: 37114120Free PMC Article
Brogi E
Virchows Arch 2022 Dec;481(6):823-837. Epub 2022 May 14 doi: 10.1007/s00428-022-03299-3. PMID: 35567633
Singh K, Paquette C, Kalife ET, Wang Y, Mangray S, Quddus MR, Steinhoff MM
Hum Pathol 2018 Aug;78:163-170. Epub 2018 May 9 doi: 10.1016/j.humpath.2018.04.026. PMID: 29753007
Bloise E, Couto HL, Massai L, Ciarmela P, Mencarelli M, Borges LE, Muscettola M, Grasso G, Amaral VF, Cassali GD, Petraglia F, Reis FM
BMC Cancer 2009 Sep 9;9:320. doi: 10.1186/1471-2407-9-320. PMID: 19740438Free PMC Article
Viacava P, Naccarato AG, Bocci G, Fanelli G, Aretini P, Lonobile A, Evangelista G, Montruccoli G, Bevilacqua G
J Pathol 2004 Oct;204(2):140-6. doi: 10.1002/path.1626. PMID: 15376259

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