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Advanced Distal Bile Duct Adenocarcinoma

MedGen UID:
1787677
Concept ID:
C5447499
Neoplastic Process
Synonym: Advanced Extrahepatic Cholangiocarcinoma

Definition

Distal bile duct adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Distal Bile Duct Adenocarcinoma

Professional guidelines

PubMed

Gorji L, Beal EW
Curr Oncol 2022 Sep 17;29(9):6674-6687. doi: 10.3390/curroncol29090524. PMID: 36135093Free PMC Article
Elvevi A, Laffusa A, Scaravaglio M, Rossi RE, Longarini R, Stagno AM, Cristoferi L, Ciaccio A, Cortinovis DL, Invernizzi P, Massironi S
Ann Hepatol 2022 Sep-Oct;27(5):100737. Epub 2022 Jul 7 doi: 10.1016/j.aohep.2022.100737. PMID: 35809836
Rizvi S, Gores GJ
Gastroenterology 2013 Dec;145(6):1215-29. Epub 2013 Oct 15 doi: 10.1053/j.gastro.2013.10.013. PMID: 24140396Free PMC Article

Recent clinical studies

Etiology

Elvevi A, Laffusa A, Scaravaglio M, Rossi RE, Longarini R, Stagno AM, Cristoferi L, Ciaccio A, Cortinovis DL, Invernizzi P, Massironi S
Ann Hepatol 2022 Sep-Oct;27(5):100737. Epub 2022 Jul 7 doi: 10.1016/j.aohep.2022.100737. PMID: 35809836
Sapisochin G, Ivanics T, Heimbach J
Hepatology 2022 Feb;75(2):455-472. Epub 2022 Jan 6 doi: 10.1002/hep.32258. PMID: 34859465
Sarcognato S, Sacchi D, Fassan M, Fabris L, Cadamuro M, Zanus G, Cataldo I, Capelli P, Baciorri F, Cacciatore M, Guido M
Pathologica 2021 Jun;113(3):158-169. doi: 10.32074/1591-951X-252. PMID: 34294934Free PMC Article
Razumilava N, Gores GJ
Lancet 2014 Jun 21;383(9935):2168-79. Epub 2014 Feb 26 doi: 10.1016/S0140-6736(13)61903-0. PMID: 24581682Free PMC Article
Rizvi S, Gores GJ
Gastroenterology 2013 Dec;145(6):1215-29. Epub 2013 Oct 15 doi: 10.1053/j.gastro.2013.10.013. PMID: 24140396Free PMC Article

Diagnosis

Elvevi A, Laffusa A, Scaravaglio M, Rossi RE, Longarini R, Stagno AM, Cristoferi L, Ciaccio A, Cortinovis DL, Invernizzi P, Massironi S
Ann Hepatol 2022 Sep-Oct;27(5):100737. Epub 2022 Jul 7 doi: 10.1016/j.aohep.2022.100737. PMID: 35809836
Sarcognato S, Sacchi D, Fassan M, Fabris L, Cadamuro M, Zanus G, Cataldo I, Capelli P, Baciorri F, Cacciatore M, Guido M
Pathologica 2021 Jun;113(3):158-169. doi: 10.32074/1591-951X-252. PMID: 34294934Free PMC Article
Razumilava N, Gores GJ
Lancet 2014 Jun 21;383(9935):2168-79. Epub 2014 Feb 26 doi: 10.1016/S0140-6736(13)61903-0. PMID: 24581682Free PMC Article
Rizvi S, Gores GJ
Gastroenterology 2013 Dec;145(6):1215-29. Epub 2013 Oct 15 doi: 10.1053/j.gastro.2013.10.013. PMID: 24140396Free PMC Article
Blechacz B, Komuta M, Roskams T, Gores GJ
Nat Rev Gastroenterol Hepatol 2011 Aug 2;8(9):512-22. doi: 10.1038/nrgastro.2011.131. PMID: 21808282Free PMC Article

Therapy

Vogel A, Segatto O, Stenzinger A, Saborowski A
Annu Rev Med 2023 Jan 27;74:293-306. Epub 2022 Sep 28 doi: 10.1146/annurev-med-042921-024707. PMID: 36170665
Sapisochin G, Ivanics T, Heimbach J
Hepatology 2022 Feb;75(2):455-472. Epub 2022 Jan 6 doi: 10.1002/hep.32258. PMID: 34859465
Mertens JC, Rizvi S, Gores GJ
Biochim Biophys Acta Mol Basis Dis 2018 Apr;1864(4 Pt B):1454-1460. Epub 2017 Aug 24 doi: 10.1016/j.bbadis.2017.08.027. PMID: 28844952Free PMC Article
Squadroni M, Tondulli L, Gatta G, Mosconi S, Beretta G, Labianca R
Crit Rev Oncol Hematol 2017 Aug;116:11-31. Epub 2016 Nov 25 doi: 10.1016/j.critrevonc.2016.11.012. PMID: 28693792
Vogel A, Saborowski A
Digestion 2017;95(3):181-185. Epub 2017 Mar 14 doi: 10.1159/000454763. PMID: 28288474

Prognosis

Elvevi A, Laffusa A, Scaravaglio M, Rossi RE, Longarini R, Stagno AM, Cristoferi L, Ciaccio A, Cortinovis DL, Invernizzi P, Massironi S
Ann Hepatol 2022 Sep-Oct;27(5):100737. Epub 2022 Jul 7 doi: 10.1016/j.aohep.2022.100737. PMID: 35809836
Izquierdo-Sanchez L, Lamarca A, La Casta A, Buettner S, Utpatel K, Klümpen HJ, Adeva J, Vogel A, Lleo A, Fabris L, Ponz-Sarvise M, Brustia R, Cardinale V, Braconi C, Vidili G, Jamieson NB, Macias RI, Jonas JP, Marzioni M, Hołówko W, Folseraas T, Kupčinskas J, Sparchez Z, Krawczyk M, Krupa Ł, Scripcariu V, Grazi GL, Landa-Magdalena A, Ijzermans JN, Evert K, Erdmann JI, López-López F, Saborowski A, Scheiter A, Santos-Laso A, Carpino G, Andersen JB, Marin JJ, Alvaro D, Bujanda L, Forner A, Valle JW, Koerkamp BG, Banales JM
J Hepatol 2022 May;76(5):1109-1121. Epub 2022 Feb 12 doi: 10.1016/j.jhep.2021.12.010. PMID: 35167909
Squadroni M, Tondulli L, Gatta G, Mosconi S, Beretta G, Labianca R
Crit Rev Oncol Hematol 2017 Aug;116:11-31. Epub 2016 Nov 25 doi: 10.1016/j.critrevonc.2016.11.012. PMID: 28693792
Rizvi S, Gores GJ
Gastroenterology 2013 Dec;145(6):1215-29. Epub 2013 Oct 15 doi: 10.1053/j.gastro.2013.10.013. PMID: 24140396Free PMC Article
Blechacz B, Komuta M, Roskams T, Gores GJ
Nat Rev Gastroenterol Hepatol 2011 Aug 2;8(9):512-22. doi: 10.1038/nrgastro.2011.131. PMID: 21808282Free PMC Article

Clinical prediction guides

Jung JH, Yoon SJ, Lee OJ, Shin SH, Han IW, Heo JS
BMC Surg 2022 Jul 4;22(1):258. doi: 10.1186/s12893-022-01649-1. PMID: 35787702Free PMC Article
Izquierdo-Sanchez L, Lamarca A, La Casta A, Buettner S, Utpatel K, Klümpen HJ, Adeva J, Vogel A, Lleo A, Fabris L, Ponz-Sarvise M, Brustia R, Cardinale V, Braconi C, Vidili G, Jamieson NB, Macias RI, Jonas JP, Marzioni M, Hołówko W, Folseraas T, Kupčinskas J, Sparchez Z, Krawczyk M, Krupa Ł, Scripcariu V, Grazi GL, Landa-Magdalena A, Ijzermans JN, Evert K, Erdmann JI, López-López F, Saborowski A, Scheiter A, Santos-Laso A, Carpino G, Andersen JB, Marin JJ, Alvaro D, Bujanda L, Forner A, Valle JW, Koerkamp BG, Banales JM
J Hepatol 2022 May;76(5):1109-1121. Epub 2022 Feb 12 doi: 10.1016/j.jhep.2021.12.010. PMID: 35167909
Amato F, Rae C, Prete MG, Braconi C
Cells 2020 Mar 30;9(4) doi: 10.3390/cells9040832. PMID: 32235647Free PMC Article
Akita M, Ajiki T, Ueno K, Tsugawa D, Tanaka M, Kido M, Toyama H, Fukumoto T
Hepatobiliary Pancreat Dis Int 2020 Apr;19(2):147-152. Epub 2020 Jan 30 doi: 10.1016/j.hbpd.2020.01.002. PMID: 32037277
Makita C, Nakamura T, Takada A, Takayama K, Suzuki M, Ishikawa Y, Azami Y, Kato T, Tsukiyama I, Kikuchi Y, Hareyama M, Murakami M, Fuwa N, Hata M, Inoue T
Radiat Oncol 2014 Jan 14;9:26. doi: 10.1186/1748-717X-9-26. PMID: 24422711Free PMC Article

Recent systematic reviews

Schizas D, Mastoraki A, Routsi E, Papapanou M, Tsapralis D, Vassiliu P, Toutouzas K, Felekouras E
Hepatobiliary Pancreat Dis Int 2020 Dec;19(6):515-523. Epub 2020 Jul 24 doi: 10.1016/j.hbpd.2020.07.004. PMID: 32753331

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