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Malignant Lacrimal System Neoplasm

MedGen UID:: 1787925
•Concept ID:: C5428719
•: Neoplastic Process

Synonym:

Malignant Lacrimal Apparatus Neoplasm

Definition

A primary or metastatic malignant neoplasm affecting the lacrimal gland or the lacrimal drainage system. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMalignant Lacrimal System Neoplasm

Pathological process
- Disease
  - Disorder by Site
    - Disorder of orbital region
      - Lacrimal apparatus disorder
        Lacrimal system cancer
        Malignant Lacrimal System Neoplasm
        Lacrimal gland cancer
        Lacrimal gland carcinoma
        Lacrimal gland adenocarcinoma
        Lacrimal gland adenoid cystic carcinoma
        Lacrimal gland carcinoma ex pleomorphic adenoma
        Lacrimal Gland Epithelial-Myoepithelial Carcinoma
        Lacrimal gland mucoepidermoid carcinoma
        Lacrimal Gland Myoepithelial Carcinoma
        Lacrimal Gland Carcinosarcoma
        Lacrimal Gland Non-Hodgkin Lymphoma
        Lacrimal Gland Diffuse Large B-Cell Lymphoma
        Lacrimal Gland Follicular Lymphoma
        Lacrimal Gland Mucosa-Associated Lymphoid Tissue Lymphoma
        Metastatic Malignant Neoplasm in the Lacrimal Gland
        Lacrimal System Carcinoma
        Lacrimal Drainage System Carcinoma
        Lacrimal Drainage System Adenocarcinoma
        Lacrimal Drainage System Adenoid Cystic Carcinoma
        Lacrimal Drainage System Lymphoepithelial Carcinoma
        Lacrimal Drainage System Mucoepidermoid Carcinoma
        Lacrimal Drainage System Squamous Cell Carcinoma
        Lacrimal System Non-Hodgkin Lymphoma
        Lacrimal Drainage System Non-Hodgkin Lymphoma
        Lacrimal Drainage System Diffuse Large B-Cell Lymphoma
        Lacrimal Drainage System Mucosa-Associated Lymphoid Tissue Lymphoma
        Lacrimal System Diffuse Large B-Cell Lymphoma
        Lacrimal System Mucosa-Associated Lymphoid Tissue Lymphoma
        Malignant Lacrimal Drainage System Neoplasm
        Lacrimal Drainage System Melanoma
        Lacrimal duct cancer
        Metastatic Malignant Neoplasm in the Lacrimal Drainage System
        Metastatic Malignant Neoplasm in the Lacrimal System

Professional guidelines

PubMed

Clinical management and outcomes of lacrimal sac squamous cell carcinoma.

Song X, Wang S, Wang J, Wang W, Wang S, Yang G, Li J, Zhu Y, Chen F, Zhu W
Head Neck 2019 Apr;41(4):974-981. Epub 2019 Jan 10 doi: 10.1002/hed.25529. PMID: 30629760

Clinical features and management of dacryops.

Ozgonul C, Uysal Y, Ayyildiz O, Kucukevcilioglu M
Orbit 2018 Aug;37(4):262-265. Epub 2018 Jan 4 doi: 10.1080/01676830.2017.1423081. PMID: 29300516

Current treatment of lacrimal gland carcinoma.

Woo KI, Kim YD, Sa HS, Esmaeli B
Curr Opin Ophthalmol 2016 Sep;27(5):449-56. doi: 10.1097/ICU.0000000000000301. PMID: 27273588

See all (73)

Recent clinical studies

Etiology

Lacrimal Sac Tumors: A Single-institution Experience, Including New Insights.

Wakasaki T, Yasumatsu R, Tanabe M, Yoshikawa H, Jiromaru R, Hashimoto K, Matsuo M, Fujimura A, Nakagawa T
In Vivo 2023 May-Jun;37(3):1219-1225. doi: 10.21873/invivo.13198. PMID: 37103086 Free PMC Article

Carcinomas of the lacrimal drainage system.

Ramberg I, Toft PB, Heegaard S
Surv Ophthalmol 2020 Nov-Dec;65(6):691-707. Epub 2020 Apr 15 doi: 10.1016/j.survophthal.2020.04.001. PMID: 32304675

More advantages in detecting bone and soft tissue metastases from prostate cancer using (18)F-PSMA PET/CT.

Pianou NK, Stavrou PZ, Vlontzou E, Rondogianni P, Exarhos DN, Datseris IE
Hell J Nucl Med 2019 Jan-Apr;22(1):6-9. Epub 2019 Mar 7 doi: 10.1967/s002449910952. PMID: 30843003

Overview of benign and malignant lacrimal gland tumors.

Gündüz AK, Yeşiltaş YS, Shields CL
Curr Opin Ophthalmol 2018 Sep;29(5):458-468. doi: 10.1097/ICU.0000000000000515. PMID: 30028745

Lacrimal Sac Tumors--A Review.

Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337

See all (556)

Diagnosis

Primary Malignant Epithelial Tumors of the Lacrimal Drainage System: A Major Review.

Singh S, Ali MJ
Orbit 2021 Jun;40(3):179-192. Epub 2020 Jun 8 doi: 10.1080/01676830.2020.1769684. PMID: 32506982

Carcinomas of the lacrimal drainage system.

Ramberg I, Toft PB, Heegaard S
Surv Ophthalmol 2020 Nov-Dec;65(6):691-707. Epub 2020 Apr 15 doi: 10.1016/j.survophthal.2020.04.001. PMID: 32304675

Overview of benign and malignant lacrimal gland tumors.

Gündüz AK, Yeşiltaş YS, Shields CL
Curr Opin Ophthalmol 2018 Sep;29(5):458-468. doi: 10.1097/ICU.0000000000000515. PMID: 30028745

Lacrimal Sac Tumors--A Review.

Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337

An Update on Tumors of the Lacrimal Gland.

Andreasen S, Esmaeli B, Holstein SL, Mikkelsen LH, Rasmussen PK, Heegaard S
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):159-172. doi: 10.22608/APO.201707. PMID: 28399336

See all (1066)

Therapy

Dysfunction of the Salivary and Lacrimal Glands After Radioiodine Therapy for Thyroid Cancer: Results of the START Study After 6-Months of Follow-Up.

Baudin C, Bressand A, Buffet C, Menegaux F, Soret M, Lê AT, Cardon T, Broggio D, Bassinet C, Huet C, Armengol G, Richardson DB, Leenhardt L, Bernier MO, Lussey-Lepoutre C
Thyroid 2023 Sep;33(9):1100-1109. Epub 2023 Jun 23 doi: 10.1089/thy.2023.0090. PMID: 37300484

The Association Between Taxane Use and Lacrimal Disorders.

McGwin G Jr, Contorno T, Vicinanzo MG, Owsley C
Curr Eye Res 2023 Sep;48(9):873-877. Epub 2023 Jun 2 doi: 10.1080/02713683.2023.2219041. PMID: 37232564

Visual outcome and ocular complications in patients with lacrimal gland carcinoma after eye-sparing surgery and adjuvant radiation therapy.

Zhao Z, Frank SJ, Ning J, Zhao J, Jiang X, Wang XA, Schefler AC, Hanna E, Moreno A, Gunn B, Ferrarotto R, Esmaeli B
Br J Ophthalmol 2023 Nov 22;107(12):1914-1919. doi: 10.1136/bjo-2022-321889. PMID: 36229179 Free PMC Article

Lymphoproliferative tumors involving the lacrimal drainage system: a major review.

Singh S, Ali MJ
Orbit 2020 Aug;39(4):276-284. Epub 2019 Jul 3 doi: 10.1080/01676830.2019.1634104. PMID: 31267826

Mycotic Infections of the Eye.

Słowik M, Biernat MM, Urbaniak-Kujda D, Kapelko-Słowik K, Misiuk-Hojło M
Adv Clin Exp Med 2015 Nov-Dec;24(6):1113-7. doi: 10.17219/acem/50572. PMID: 26771986

See all (333)

Prognosis

More advantages in detecting bone and soft tissue metastases from prostate cancer using (18)F-PSMA PET/CT.

Pianou NK, Stavrou PZ, Vlontzou E, Rondogianni P, Exarhos DN, Datseris IE
Hell J Nucl Med 2019 Jan-Apr;22(1):6-9. Epub 2019 Mar 7 doi: 10.1967/s002449910952. PMID: 30843003

Chen LYC, Mattman A, Seidman MA, Carruthers MN
Haematologica 2019 Mar;104(3):444-455. Epub 2019 Jan 31 doi: 10.3324/haematol.2018.205526. PMID: 30705099 Free PMC Article

Overview of benign and malignant lacrimal gland tumors.

Gündüz AK, Yeşiltaş YS, Shields CL
Curr Opin Ophthalmol 2018 Sep;29(5):458-468. doi: 10.1097/ICU.0000000000000515. PMID: 30028745

Lacrimal Sac Tumors--A Review.

Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337

An Update on Tumors of the Lacrimal Gland.

Andreasen S, Esmaeli B, Holstein SL, Mikkelsen LH, Rasmussen PK, Heegaard S
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):159-172. doi: 10.22608/APO.201707. PMID: 28399336

See all (448)

Clinical prediction guides

Dacryops and clinical diagnostic challenges.

Alsarhani WK, Al-Sharif EM, Al-Faky YH, Alkatan HM, Maktabi AM, Alsuhaibani AH
Can J Ophthalmol 2022 Dec;57(6):388-393. Epub 2021 Jul 26 doi: 10.1016/j.jcjo.2021.06.014. PMID: 34324876

Human Papillomavirus Related Neoplasia of the Ocular Adnexa.

Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388 Free PMC Article

Dacryops - A review.

Tanaboonyawat S, Idowu OO, Copperman TS, Vagefi MR, Kersten RC
Orbit 2020 Apr;39(2):128-134. Epub 2019 Sep 12 doi: 10.1080/01676830.2019.1608564. PMID: 31512543

More advantages in detecting bone and soft tissue metastases from prostate cancer using (18)F-PSMA PET/CT.

Pianou NK, Stavrou PZ, Vlontzou E, Rondogianni P, Exarhos DN, Datseris IE
Hell J Nucl Med 2019 Jan-Apr;22(1):6-9. Epub 2019 Mar 7 doi: 10.1967/s002449910952. PMID: 30843003

Mycotic Infections of the Eye.

Słowik M, Biernat MM, Urbaniak-Kujda D, Kapelko-Słowik K, Misiuk-Hojło M
Adv Clin Exp Med 2015 Nov-Dec;24(6):1113-7. doi: 10.17219/acem/50572. PMID: 26771986

See all (224)

Recent systematic reviews

Recurrence rate of pleomorphic adenoma of the lacrimal gland: systematic review and meta-analysis.

Van Swol EG, Gupta A, Nguyen SA, Eiseman AS
Orbit 2024 Apr;43(2):208-216. Epub 2023 Oct 23 doi: 10.1080/01676830.2023.2269252. PMID: 37870812

Holding back the tears: is there a role for marsupialisation?

Chiu SJ, Currie ZI, Tan JH
BMJ Open Ophthalmol 2022 Aug;7(1) doi: 10.1136/bmjophth-2022-000985. PMID: 36161857 Free PMC Article

Melanoma of the lacrimal drainage system: A systematic review.

Vinciguerra A, Rampi A, Giordano Resti A, Barbieri D, Bussi M, Trimarchi M
Head Neck 2021 Jul;43(7):2240-2252. Epub 2021 Apr 12 doi: 10.1002/hed.26705. PMID: 33843111

Ectopic Lacrimal Gland Tissue: A Systematic Review.

Nagendran S, Alsamnan M, Strianese D, Malhotra R
Ophthalmic Plast Reconstr Surg 2020 Nov/Dec;36(6):540-544. doi: 10.1097/IOP.0000000000001621. PMID: 32205779

A systematic review of sinonasal oncocytomas and oncocytic carcinomas: Diagnosis, management, and technical considerations.

Hodzic Z, Rowan NR, Kashiwazaki R, Willson TJ, Wang EW, Lee SE
Int Forum Allergy Rhinol 2017 May;7(5):514-524. Epub 2017 Jan 16 doi: 10.1002/alr.21902. PMID: 28092140

See all (10)

MedGen

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Malignant Lacrimal System Neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Recent activity