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Aortic annulus calcification

MedGen UID:
1788204
•Concept ID:
C5539666
•
Pathologic Function
Synonym: Aortic annular calcification
 
HPO: HP:0033538

Definition

Pathological deposition of calcium salts in the aortic annulus, a fibrous ring-like structure found at the insertion point of the basal attachments of the aortic valve leaflets within the left ventricular outflow tract. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAortic annulus calcification

Professional guidelines

PubMed

Paravalvular Leak After Transcatheter Aortic Valve Implantation Its Incidence, Diagnosis, Clinical Implications, Prevention, Management, and Future Perspectives: A Review Article.
Bhushan S, Huang X, Li Y, He S, Mao L, Hong W, Xiao Z
Curr Probl Cardiol 2022 Oct;47(10):100957. Epub 2021 Aug 5 doi: 10.1016/j.cpcardiol.2021.100957. PMID: 34364915
Management and Outcome of Residual Aortic Regurgitation After Transcatheter Aortic Valve Implantation.
Koifman E, Didier R, Garcia-Garcia H, Weissman G, Ertel AW, Kiramijyan S, Steinvil A, Rogers T, Patel N, Kumar S, Tavil-Shatelyan A, Ben-Dor I, Pichard AD, Torguson R, Gai J, Satler LF, Waksman R
Am J Cardiol 2017 Aug 15;120(4):632-639. Epub 2017 May 31 doi: 10.1016/j.amjcard.2017.05.033. PMID: 28673639
Advances in percutaneous treatment for adult valvular heart disease.
Wong MC, Clark DJ, Horrigan MC, Grube E, Matalanis G, Farouque HM
Intern Med J 2009 Jul;39(7):465-74. doi: 10.1111/j.1445-5994.2008.01877.x. PMID: 19664157

Recent clinical studies

Etiology

Predictors of Paravalvular Regurgitation After Transcatheter Aortic Valve Implantation for Aortic Stenosis Using New-Generation Balloon-Expandable SAPIEN 3.
Kaneko H, Hoelschermann F, Tambor G, Yoon SH, Neuss M, Butter C
Am J Cardiol 2017 Feb 15;119(4):618-622. Epub 2016 Nov 16 doi: 10.1016/j.amjcard.2016.10.047. PMID: 28010874

Diagnosis

The extent of aortic annulus calcification is a predictor of postprocedural eccentricity and paravalvular regurgitation: a pre- and postinterventional cardiac computed tomography angiography study.
Bekeredjian R, Bodingbauer D, Hofmann NP, Greiner S, Schuetz M, Geis NA, Kauczor HU, Bryant M, Chorianopoulos E, Pleger ST, Mereles D, Katus HA, Korosoglou G
J Invasive Cardiol 2015 Mar;27(3):172-80. PMID: 25740972

Therapy

The extent of aortic annulus calcification is a predictor of postprocedural eccentricity and paravalvular regurgitation: a pre- and postinterventional cardiac computed tomography angiography study.
Bekeredjian R, Bodingbauer D, Hofmann NP, Greiner S, Schuetz M, Geis NA, Kauczor HU, Bryant M, Chorianopoulos E, Pleger ST, Mereles D, Katus HA, Korosoglou G
J Invasive Cardiol 2015 Mar;27(3):172-80. PMID: 25740972
Evaluation of aortic root and valve calcifications by multi-detector computed tomography.
Rivard AL, Bartel T, Bianco RW, O'Donnell KS, Bonatti J, Dichtl W, Cury RC, Feuchtner GM
J Heart Valve Dis 2009 Nov;18(6):662-70. PMID: 20099715

Prognosis

Predictors of Paravalvular Regurgitation After Transcatheter Aortic Valve Implantation for Aortic Stenosis Using New-Generation Balloon-Expandable SAPIEN 3.
Kaneko H, Hoelschermann F, Tambor G, Yoon SH, Neuss M, Butter C
Am J Cardiol 2017 Feb 15;119(4):618-622. Epub 2016 Nov 16 doi: 10.1016/j.amjcard.2016.10.047. PMID: 28010874
The extent of aortic annulus calcification is a predictor of postprocedural eccentricity and paravalvular regurgitation: a pre- and postinterventional cardiac computed tomography angiography study.
Bekeredjian R, Bodingbauer D, Hofmann NP, Greiner S, Schuetz M, Geis NA, Kauczor HU, Bryant M, Chorianopoulos E, Pleger ST, Mereles D, Katus HA, Korosoglou G
J Invasive Cardiol 2015 Mar;27(3):172-80. PMID: 25740972

Clinical prediction guides

Predictors of Paravalvular Regurgitation After Transcatheter Aortic Valve Implantation for Aortic Stenosis Using New-Generation Balloon-Expandable SAPIEN 3.
Kaneko H, Hoelschermann F, Tambor G, Yoon SH, Neuss M, Butter C
Am J Cardiol 2017 Feb 15;119(4):618-622. Epub 2016 Nov 16 doi: 10.1016/j.amjcard.2016.10.047. PMID: 28010874
The extent of aortic annulus calcification is a predictor of postprocedural eccentricity and paravalvular regurgitation: a pre- and postinterventional cardiac computed tomography angiography study.
Bekeredjian R, Bodingbauer D, Hofmann NP, Greiner S, Schuetz M, Geis NA, Kauczor HU, Bryant M, Chorianopoulos E, Pleger ST, Mereles D, Katus HA, Korosoglou G
J Invasive Cardiol 2015 Mar;27(3):172-80. PMID: 25740972

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