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Invasive Male Breast Carcinoma

MedGen UID:
1788755
•Concept ID:
C5447280
•
Neoplastic Process

Definition

A rare invasive carcinoma that arises from the male breast. Morphologically, it is similar to the invasive carcinomas that arise from the female breast. It usually develops in the retroareolar region. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInvasive Male Breast Carcinoma

Professional guidelines

PubMed

The multifaceted mechanisms of pristimerin in the treatment of tumors state-of-the-art.
Wang Y, Feng W, Wang X, Li X, Mou Y, Wang X, Zhang Y
Biomed Pharmacother 2022 Oct;154:113575. Epub 2022 Aug 18 doi: 10.1016/j.biopha.2022.113575. PMID: 35988422
Breast cancer risk in transgender people receiving hormone treatment: nationwide cohort study in the Netherlands.
de Blok CJM, Wiepjes CM, Nota NM, van Engelen K, Adank MA, Dreijerink KMA, Barbé E, Konings IRHM, den Heijer M
BMJ 2019 May 14;365:l1652. doi: 10.1136/bmj.l1652. PMID: 31088823Free PMC Article
Surgical management and gynecologic care of the transgender patient.
Schmidt M, Ditrio L, Shute B, Luciano D
Curr Opin Obstet Gynecol 2019 Aug;31(4):228-234. doi: 10.1097/GCO.0000000000000553. PMID: 31045656

Recent clinical studies

Etiology

Papillary lesions of the breast.
Kulka J, Madaras L, Floris G, Lax SF
Virchows Arch 2022 Jan;480(1):65-84. Epub 2021 Nov 3 doi: 10.1007/s00428-021-03182-7. PMID: 34734332Free PMC Article
Male breast cancer: an update.
Fox S, Speirs V, Shaaban AM
Virchows Arch 2022 Jan;480(1):85-93. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03190-7. PMID: 34458944
Genetic Factors, Adherence to Healthy Lifestyle Behavior, and Risk of Invasive Breast Cancer Among Women in the UK Biobank.
Arthur RS, Wang T, Xue X, Kamensky V, Rohan TE
J Natl Cancer Inst 2020 Sep 1;112(9):893-901. doi: 10.1093/jnci/djz241. PMID: 31899501Free PMC Article
Breast cancer risk in transgender people receiving hormone treatment: nationwide cohort study in the Netherlands.
de Blok CJM, Wiepjes CM, Nota NM, van Engelen K, Adank MA, Dreijerink KMA, Barbé E, Konings IRHM, den Heijer M
BMJ 2019 May 14;365:l1652. doi: 10.1136/bmj.l1652. PMID: 31088823Free PMC Article
Male breast carcinoma.
Meguerditchian AN, Falardeau M, Martin G
Can J Surg 2002 Aug;45(4):296-302. PMID: 12174988Free PMC Article

Diagnosis

Papillary lesions of the breast.
Kulka J, Madaras L, Floris G, Lax SF
Virchows Arch 2022 Jan;480(1):65-84. Epub 2021 Nov 3 doi: 10.1007/s00428-021-03182-7. PMID: 34734332Free PMC Article
Male breast cancer: an update.
Fox S, Speirs V, Shaaban AM
Virchows Arch 2022 Jan;480(1):85-93. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03190-7. PMID: 34458944
The diagnosis of male breast cancer.
Nofal MN, Yousef AJ
Neth J Med 2019 Dec;77(10):356-359. PMID: 31880271
Neuroendocrine Tumors of the Breast.
Rosen LE, Gattuso P
Arch Pathol Lab Med 2017 Nov;141(11):1577-1581. doi: 10.5858/arpa.2016-0364-RS. PMID: 29072945
Male breast carcinoma.
Meguerditchian AN, Falardeau M, Martin G
Can J Surg 2002 Aug;45(4):296-302. PMID: 12174988Free PMC Article

Therapy

Abemaciclib plus endocrine therapy for hormone receptor-positive, HER2-negative, node-positive, high-risk early breast cancer (monarchE): results from a preplanned interim analysis of a randomised, open-label, phase 3 trial.
Johnston SRD, Toi M, O'Shaughnessy J, Rastogi P, Campone M, Neven P, Huang CS, Huober J, Jaliffe GG, Cicin I, Tolaney SM, Goetz MP, Rugo HS, Senkus E, Testa L, Del Mastro L, Shimizu C, Wei R, Shahir A, Munoz M, San Antonio B, André V, Harbeck N, Martin M; monarchE Committee Members
Lancet Oncol 2023 Jan;24(1):77-90. Epub 2022 Dec 6 doi: 10.1016/S1470-2045(22)00694-5. PMID: 36493792
Effect of Metformin vs Placebo on Invasive Disease-Free Survival in Patients With Breast Cancer: The MA.32 Randomized Clinical Trial.
Goodwin PJ, Chen BE, Gelmon KA, Whelan TJ, Ennis M, Lemieux J, Ligibel JA, Hershman DL, Mayer IA, Hobday TJ, Bliss JM, Rastogi P, Rabaglio-Poretti M, Mukherjee SD, Mackey JR, Abramson VG, Oja C, Wesolowski R, Thompson AM, Rea DW, Stos PM, Shepherd LE, Stambolic V, Parulekar WR
JAMA 2022 May 24;327(20):1963-1973. doi: 10.1001/jama.2022.6147. PMID: 35608580Free PMC Article
Palbociclib for Residual High-Risk Invasive HR-Positive and HER2-Negative Early Breast Cancer-The Penelope-B Trial.
Loibl S, Marmé F, Martin M, Untch M, Bonnefoi H, Kim SB, Bear H, McCarthy N, Melé Olivé M, Gelmon K, García-Sáenz J, Kelly CM, Reimer T, Toi M, Rugo HS, Denkert C, Gnant M, Makris A, Koehler M, Huang-Bartelett C, Lechuga Frean MJ, Colleoni M, Werutsky G, Seiler S, Burchardi N, Nekljudova V, von Minckwitz G
J Clin Oncol 2021 May 10;39(14):1518-1530. Epub 2021 Apr 1 doi: 10.1200/JCO.20.03639. PMID: 33793299
Safety, pharmacokinetics, and antitumour activity of trastuzumab deruxtecan (DS-8201), a HER2-targeting antibody-drug conjugate, in patients with advanced breast and gastric or gastro-oesophageal tumours: a phase 1 dose-escalation study.
Doi T, Shitara K, Naito Y, Shimomura A, Fujiwara Y, Yonemori K, Shimizu C, Shimoi T, Kuboki Y, Matsubara N, Kitano A, Jikoh T, Lee C, Fujisaki Y, Ogitani Y, Yver A, Tamura K
Lancet Oncol 2017 Nov;18(11):1512-1522. Epub 2017 Oct 13 doi: 10.1016/S1470-2045(17)30604-6. PMID: 29037983
Physical activity, sedentary behaviour, diet, and cancer: an update and emerging new evidence.
Kerr J, Anderson C, Lippman SM
Lancet Oncol 2017 Aug;18(8):e457-e471. Epub 2017 Jul 26 doi: 10.1016/S1470-2045(17)30411-4. PMID: 28759385Free PMC Article

Prognosis

Male breast cancer: an update.
Fox S, Speirs V, Shaaban AM
Virchows Arch 2022 Jan;480(1):85-93. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03190-7. PMID: 34458944
Breast cancer risk in transgender people receiving hormone treatment: nationwide cohort study in the Netherlands.
de Blok CJM, Wiepjes CM, Nota NM, van Engelen K, Adank MA, Dreijerink KMA, Barbé E, Konings IRHM, den Heijer M
BMJ 2019 May 14;365:l1652. doi: 10.1136/bmj.l1652. PMID: 31088823Free PMC Article
Neuroendocrine Tumors of the Breast.
Rosen LE, Gattuso P
Arch Pathol Lab Med 2017 Nov;141(11):1577-1581. doi: 10.5858/arpa.2016-0364-RS. PMID: 29072945
Physical activity, sedentary behaviour, diet, and cancer: an update and emerging new evidence.
Kerr J, Anderson C, Lippman SM
Lancet Oncol 2017 Aug;18(8):e457-e471. Epub 2017 Jul 26 doi: 10.1016/S1470-2045(17)30411-4. PMID: 28759385Free PMC Article
Male breast carcinoma.
Meguerditchian AN, Falardeau M, Martin G
Can J Surg 2002 Aug;45(4):296-302. PMID: 12174988Free PMC Article

Clinical prediction guides

Papillary lesions of the breast.
Kulka J, Madaras L, Floris G, Lax SF
Virchows Arch 2022 Jan;480(1):65-84. Epub 2021 Nov 3 doi: 10.1007/s00428-021-03182-7. PMID: 34734332Free PMC Article
Genetic Factors, Adherence to Healthy Lifestyle Behavior, and Risk of Invasive Breast Cancer Among Women in the UK Biobank.
Arthur RS, Wang T, Xue X, Kamensky V, Rohan TE
J Natl Cancer Inst 2020 Sep 1;112(9):893-901. doi: 10.1093/jnci/djz241. PMID: 31899501Free PMC Article
(89)Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer.
Bensch F, van der Veen EL, Lub-de Hooge MN, Jorritsma-Smit A, Boellaard R, Kok IC, Oosting SF, Schröder CP, Hiltermann TJN, van der Wekken AJ, Groen HJM, Kwee TC, Elias SG, Gietema JA, Bohorquez SS, de Crespigny A, Williams SP, Mancao C, Brouwers AH, Fine BM, de Vries EGE
Nat Med 2018 Dec;24(12):1852-1858. Epub 2018 Nov 26 doi: 10.1038/s41591-018-0255-8. PMID: 30478423
Granulomatous mastitis: etiology, imaging, pathology, treatment, and clinical findings.
Barreto DS, Sedgwick EL, Nagi CS, Benveniste AP
Breast Cancer Res Treat 2018 Oct;171(3):527-534. Epub 2018 Jul 3 doi: 10.1007/s10549-018-4870-3. PMID: 29971624
Physical activity, sedentary behaviour, diet, and cancer: an update and emerging new evidence.
Kerr J, Anderson C, Lippman SM
Lancet Oncol 2017 Aug;18(8):e457-e471. Epub 2017 Jul 26 doi: 10.1016/S1470-2045(17)30411-4. PMID: 28759385Free PMC Article

Recent systematic reviews

Risk Factors for Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.
Mao J, Zhang Q, Zhang H, Zheng K, Wang R, Wang G
Front Endocrinol (Lausanne) 2020;11:265. Epub 2020 May 15 doi: 10.3389/fendo.2020.00265. PMID: 32477264Free PMC Article
Breast cancer in transgender patients: A systematic review. Part 2: Female to Male.
Stone JP, Hartley RL, Temple-Oberle C
Eur J Surg Oncol 2018 Oct;44(10):1463-1468. Epub 2018 Jul 5 doi: 10.1016/j.ejso.2018.06.021. PMID: 30037639
Association Between CHEK2*1100delC and Breast Cancer: A Systematic Review and Meta-Analysis.
Liang M, Zhang Y, Sun C, Rizeq FK, Min M, Shi T, Sun Y
Mol Diagn Ther 2018 Aug;22(4):397-407. doi: 10.1007/s40291-018-0344-x. PMID: 29909568
5-alpha Reductase Inhibitors and risk of male breast cancer: a systematic review and meta-analysis.
Wang J, Zhao S, Luo L, Li E, Li X, Zhao Z
Int Braz J Urol 2018 Sep-Oct;44(5):865-873. doi: 10.1590/S1677-5538.IBJU.2017.0531. PMID: 29697934Free PMC Article
Paget's disease of the male breast in the 21st century: A systematic review.
Adams SJ, Kanthan R
Breast 2016 Oct;29:14-23. Epub 2016 Jul 6 doi: 10.1016/j.breast.2016.06.015. PMID: 27394005

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