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Primary vesicoureteral reflux

MedGen UID:
1788979
Concept ID:
C5539786
Disease or Syndrome
Synonyms: Primary Vesicoureteral Reflux; Reflux, Primary Vesicoureteral; Vesicoureteral Reflux, Primary
 
HPO: HP:0033738

Definition

Vesicoureteral reflux due to abnormalities in ureterovesical junction, e.g. ectopic insertion of the ureter or short intravesical tunnel at the ureterovesical junction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPrimary vesicoureteral reflux

Professional guidelines

PubMed

Fonseca FF, Tanno FY, Nguyen HT
Pediatr Clin North Am 2012 Aug;59(4):819-34. Epub 2012 Jun 22 doi: 10.1016/j.pcl.2012.05.012. PMID: 22857830
Diamond DA, Mattoo TK
N Engl J Med 2012 Mar 29;366(13):1218-26. doi: 10.1056/NEJMct1108922. PMID: 22455416
Peters CA, Skoog SJ, Arant BS Jr, Copp HL, Elder JS, Hudson RG, Khoury AE, Lorenzo AJ, Pohl HG, Shapiro E, Snodgrass WT, Diaz M
J Urol 2010 Sep;184(3):1134-44. Epub 2010 Jul 21 doi: 10.1016/j.juro.2010.05.065. PMID: 20650499

Recent clinical studies

Etiology

Mattoo TK, Mohammad D
Pediatr Clin North Am 2022 Dec;69(6):1115-1129. Epub 2022 Oct 29 doi: 10.1016/j.pcl.2022.07.007. PMID: 36880925
Marcellino A, Bloise S, Fraternali R, Pirone C, Brandino G, Testa A, Filippi L, Lubrano R
Urology 2022 Oct;168:195-200. Epub 2022 Jun 30 doi: 10.1016/j.urology.2022.06.020. PMID: 35780944
Benaired AM, Zahaf H, Bourazi N
J Endourol 2021 Dec;35(12):1808-1812. doi: 10.1089/end.2020.1217. PMID: 34060919
Fukui S, Watanabe M, Yoshino K
Int J Urol 2013 Jun;20(6):631-6. Epub 2012 Nov 27 doi: 10.1111/iju.12015. PMID: 23186044
Mattoo TK
Adv Chronic Kidney Dis 2011 Sep;18(5):348-54. doi: 10.1053/j.ackd.2011.07.006. PMID: 21896376Free PMC Article

Diagnosis

Mattoo TK, Mohammad D
Pediatr Clin North Am 2022 Dec;69(6):1115-1129. Epub 2022 Oct 29 doi: 10.1016/j.pcl.2022.07.007. PMID: 36880925
Andrioli V, Regacini R, Aguiar W
Int Braz J Urol 2020 Mar-Apr;46(2):262-268. doi: 10.1590/S1677-5538.IBJU.2020.02.02. PMID: 32022517Free PMC Article
Garin EH
Pediatr Nephrol 2019 Sep;34(9):1513-1519. Epub 2018 Aug 21 doi: 10.1007/s00467-018-4045-9. PMID: 30132079
Nickavar A, Hajizadeh N, Lahouti Harahdashti A
Acta Med Iran 2015;53(6):376-9. PMID: 26069177
Mattoo TK
Adv Chronic Kidney Dis 2011 Sep;18(5):348-54. doi: 10.1053/j.ackd.2011.07.006. PMID: 21896376Free PMC Article

Therapy

Mittal S, Eftekharzadeh S, Aghababian A, Weaver J, Fischer K, Long CJ, Weiss DA, Van Batavia J, Srinivasan AK, Shukla AR
J Pediatr Urol 2022 Aug;18(4):517.e1-517.e5. Epub 2022 Apr 13 doi: 10.1016/j.jpurol.2022.04.005. PMID: 35654725
Payza AD, Hoşgör M, Serdaroğlu E, Sencan A
J Pediatr Urol 2019 Oct;15(5):515.e1-515.e8. Epub 2019 Jul 13 doi: 10.1016/j.jpurol.2019.07.005. PMID: 31420285
Garin EH
Pediatr Nephrol 2019 Sep;34(9):1513-1519. Epub 2018 Aug 21 doi: 10.1007/s00467-018-4045-9. PMID: 30132079
Tekgül S, Riedmiller H, Hoebeke P, Kočvara R, Nijman RJ, Radmayr C, Stein R, Dogan HS; European Association of Urology
Eur Urol 2012 Sep;62(3):534-42. Epub 2012 Jun 5 doi: 10.1016/j.eururo.2012.05.059. PMID: 22698573
Peters CA, Skoog SJ, Arant BS Jr, Copp HL, Elder JS, Hudson RG, Khoury AE, Lorenzo AJ, Pohl HG, Shapiro E, Snodgrass WT, Diaz M
J Urol 2010 Sep;184(3):1134-44. Epub 2010 Jul 21 doi: 10.1016/j.juro.2010.05.065. PMID: 20650499

Prognosis

Gavrilovici C, Dusa CP, Iliescu Halitchi C, Lupu VV, Spoiala EL, Bogos RA, Mocanu A, Gafencu M, Lupu A, Stoica C, Starcea IM
Int J Mol Sci 2023 Apr 26;24(9) doi: 10.3390/ijms24097904. PMID: 37175609Free PMC Article
Vachvanichsanong P, Dissaneewate P, McNeil E
Nephrology (Carlton) 2016 Apr;21(4):335-40. doi: 10.1111/nep.12615. PMID: 26370584
Arlen AM, Garcia-Roig M, Weiss AD, Leong T, Cooper CS, Kirsch AJ
J Urol 2016 Apr;195(4 Pt 2):1294-9. Epub 2015 Mar 23 doi: 10.1016/j.juro.2015.03.094. PMID: 25813448
Nickavar A, Hajizadeh N, Lahouti Harahdashti A
Acta Med Iran 2015;53(6):376-9. PMID: 26069177
Mattoo TK
Adv Chronic Kidney Dis 2011 Sep;18(5):348-54. doi: 10.1053/j.ackd.2011.07.006. PMID: 21896376Free PMC Article

Clinical prediction guides

Gavrilovici C, Dusa CP, Iliescu Halitchi C, Lupu VV, Spoiala EL, Bogos RA, Mocanu A, Gafencu M, Lupu A, Stoica C, Starcea IM
Int J Mol Sci 2023 Apr 26;24(9) doi: 10.3390/ijms24097904. PMID: 37175609Free PMC Article
Arlen AM, Garcia-Roig M, Weiss AD, Leong T, Cooper CS, Kirsch AJ
J Urol 2016 Apr;195(4 Pt 2):1294-9. Epub 2015 Mar 23 doi: 10.1016/j.juro.2015.03.094. PMID: 25813448
Nickavar A, Hajizadeh N, Lahouti Harahdashti A
Acta Med Iran 2015;53(6):376-9. PMID: 26069177
Fukui S, Watanabe M, Yoshino K
Int J Urol 2013 Jun;20(6):631-6. Epub 2012 Nov 27 doi: 10.1111/iju.12015. PMID: 23186044
Mattoo TK
Adv Chronic Kidney Dis 2011 Sep;18(5):348-54. doi: 10.1053/j.ackd.2011.07.006. PMID: 21896376Free PMC Article

Recent systematic reviews

Basiri A, Ziaeefar P, Khoshdel A, Fattahi P, Mafi Balani M, Tofighi Zavareh MA
Urol J 2023 Dec 26;20(6):385-396. doi: 10.22037/uj.v20i06.8095. PMID: 38158632
Mina-Riascos SH, Fernández N, García-Perdomo HA
Eur J Pediatr 2021 May;180(5):1383-1391. Epub 2021 Jan 20 doi: 10.1007/s00431-021-03948-w. PMID: 33474581

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