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Mucoepidermoid cancer of the parotid

MedGen UID:
1789042
•Concept ID:
C5542992
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMucoepidermoid cancer of the parotid

Professional guidelines

PubMed

Mucoepidermoid carcinoma of the parotid gland: Twenty-year experience in treatment and outcomes.
Chan SA, Van Abel KM, Lewis JE, Routman DM, Garcia JJ, Karp EE, Price DL, Janus JR, Kasperbauer JL, Moore EJ
Head Neck 2021 Sep;43(9):2663-2671. Epub 2021 May 1 doi: 10.1002/hed.26735. PMID: 33931913
Diagnosis and Management of Malignant Salivary Gland Tumors of the Parotid Gland.
Lewis AG, Tong T, Maghami E
Otolaryngol Clin North Am 2016 Apr;49(2):343-80. doi: 10.1016/j.otc.2015.11.001. PMID: 27040585
Management of salivary gland tumors.
Andry G, Hamoir M, Locati LD, Licitra L, Langendijk JA
Expert Rev Anticancer Ther 2012 Sep;12(9):1161-8. doi: 10.1586/era.12.92. PMID: 23098116

Recent clinical studies

Etiology

Rearrangement of KMT2A Characterizes a Subset of Pediatric Parotid Mucoepidermoid Carcinomas Arising Metachronous to Acute Lymphoblastic Leukemia.
Othman BK, Steiner P, Leivo I, Skálová A
Fetal Pediatr Pathol 2023 Oct;42(5):796-807. Epub 2023 Jul 30 doi: 10.1080/15513815.2023.2241903. PMID: 37517063
Elective neck dissection in salivary gland malignancies: Systematic review and meta-analysis.
Yan F, Lao WP, Nguyen SA, Sharma AK, Day TA
Head Neck 2022 Feb;44(2):505-517. Epub 2021 Dec 4 doi: 10.1002/hed.26923. PMID: 34862810
Mucoepidermoid carcinoma of the parotid gland: Twenty-year experience in treatment and outcomes.
Chan SA, Van Abel KM, Lewis JE, Routman DM, Garcia JJ, Karp EE, Price DL, Janus JR, Kasperbauer JL, Moore EJ
Head Neck 2021 Sep;43(9):2663-2671. Epub 2021 May 1 doi: 10.1002/hed.26735. PMID: 33931913
Mucoepidermoid carcinoma of the head and neck in children.
Dombrowski ND, Wolter NE, Irace AL, Cunningham MJ, Mack JW, Marcus KJ, Vargas SO, Perez-Atayde AR, Robson CD, Rahbar R
Int J Pediatr Otorhinolaryngol 2019 May;120:93-99. Epub 2019 Feb 10 doi: 10.1016/j.ijporl.2019.02.020. PMID: 30772619
Diagnosis and Management of Malignant Salivary Gland Tumors of the Parotid Gland.
Lewis AG, Tong T, Maghami E
Otolaryngol Clin North Am 2016 Apr;49(2):343-80. doi: 10.1016/j.otc.2015.11.001. PMID: 27040585

Diagnosis

Mucoepidermoid carcinoma. An update and review of the literature.
Peraza A, Gómez R, Beltran J, Amarista FJ
J Stomatol Oral Maxillofac Surg 2020 Dec;121(6):713-720. Epub 2020 Jun 18 doi: 10.1016/j.jormas.2020.06.003. PMID: 32565266
Diagnosis and Management of Malignant Salivary Gland Tumors of the Parotid Gland.
Lewis AG, Tong T, Maghami E
Otolaryngol Clin North Am 2016 Apr;49(2):343-80. doi: 10.1016/j.otc.2015.11.001. PMID: 27040585
Mucoepidermoid carcinoma.
Devaraju R, Gantala R, Aitha H, Gotoor SG
BMJ Case Rep 2014 Aug 1;2014:bcr-2013-202776. doi: 10.1136/bcr-2013-202776. PMID: 25085946Free PMC Article
Intraparotid schwannoma.
McCarthy WA, Cox BL
Arch Pathol Lab Med 2014 Jul;138(7):982-5. doi: 10.5858/arpa.2013-0014-RS. PMID: 24978928
Submandibular gland tumors.
Hanna DC, Clairmont AA
Plast Reconstr Surg 1978 Feb;61(2):198-203. doi: 10.1097/00006534-197802000-00007. PMID: 202980

Therapy

Prognosis of Pediatric Patients With Mucoepidermoid Carcinoma of the Parotid Gland.
Li MZ, Mao MH, Feng ZE, Li JZ, Li H, Qin LZ, Li JH, Huang X, Xing RD, Han ZX
J Craniofac Surg 2020 Mar/Apr;31(2):e123-e126. doi: 10.1097/SCS.0000000000006048. PMID: 31764567
Ado-trastuzumab emtansine (T-DM1) in patients with HER2-amplified tumors excluding breast and gastric/gastroesophageal junction (GEJ) adenocarcinomas: results from the NCI-MATCH trial (EAY131) subprotocol Q.
Jhaveri KL, Wang XV, Makker V, Luoh SW, Mitchell EP, Zwiebel JA, Sharon E, Gray RJ, Li S, McShane LM, Rubinstein LV, Patton D, Williams PM, Hamilton SR, Conley BA, Arteaga CL, Harris LN, O'Dwyer PJ, Chen AP, Flaherty KT
Ann Oncol 2019 Nov 1;30(11):1821-1830. doi: 10.1093/annonc/mdz291. PMID: 31504139Free PMC Article
Role of fine-needle aspiration in post liver transplant patients: A clinical/cytological review.
Rohra P, Mir F, Lin DM, Furlan K, Javidiparsijani S, Lucero D, Gattuso P
Diagn Cytopathol 2019 May;47(5):434-438. Epub 2018 Dec 28 doi: 10.1002/dc.24133. PMID: 30593732
Salivary gland tumors in children: a retrospective clinical review.
Varan A, Akyüz C, Ataş E, Yücel T, Aydın B, Yalçın B, Kutluk T, Büyükpamukçu M
Pediatr Hematol Oncol 2014 Nov;31(8):681-6. Epub 2014 Sep 23 doi: 10.3109/08880018.2014.942936. PMID: 25247345
Management of salivary gland tumors.
Andry G, Hamoir M, Locati LD, Licitra L, Langendijk JA
Expert Rev Anticancer Ther 2012 Sep;12(9):1161-8. doi: 10.1586/era.12.92. PMID: 23098116

Prognosis

Rearrangement of KMT2A Characterizes a Subset of Pediatric Parotid Mucoepidermoid Carcinomas Arising Metachronous to Acute Lymphoblastic Leukemia.
Othman BK, Steiner P, Leivo I, Skálová A
Fetal Pediatr Pathol 2023 Oct;42(5):796-807. Epub 2023 Jul 30 doi: 10.1080/15513815.2023.2241903. PMID: 37517063
Management and prognosis of cancers in the accessory parotid gland.
Han X, Zhang X, Gao Y, Pang P, Liu F, Sun C
J Int Med Res 2018 Dec;46(12):4930-4933. Epub 2018 Oct 5 doi: 10.1177/0300060518767792. PMID: 30289052Free PMC Article
Diagnosis and Management of Malignant Salivary Gland Tumors of the Parotid Gland.
Lewis AG, Tong T, Maghami E
Otolaryngol Clin North Am 2016 Apr;49(2):343-80. doi: 10.1016/j.otc.2015.11.001. PMID: 27040585
Intraparotid schwannoma.
McCarthy WA, Cox BL
Arch Pathol Lab Med 2014 Jul;138(7):982-5. doi: 10.5858/arpa.2013-0014-RS. PMID: 24978928
Submandibular gland tumors.
Hanna DC, Clairmont AA
Plast Reconstr Surg 1978 Feb;61(2):198-203. doi: 10.1097/00006534-197802000-00007. PMID: 202980

Clinical prediction guides

Number of positive lymph nodes is superior to neck stage of the 8th AJCC in predicting prognosis in parotid mucoepidermoid carcinoma.
Li W, Yu W, Cao H, Zhang A
Head Neck 2023 Oct;45(10):2613-2618. Epub 2023 Aug 18 doi: 10.1002/hed.27486. PMID: 37594176
Utility of Elective Neck Dissection in Clinically Node-Negative Parotid Malignancy.
Vedula S, Shah YS, Barinsky GL, Baredes S, Park RCW
Otolaryngol Head Neck Surg 2023 Oct;169(4):917-927. Epub 2023 Feb 17 doi: 10.1002/ohn.264. PMID: 36807904
Intermediate-grade carcinoma of the parotid and the impact of adjuvant radiation.
North L, Stadler M, Massey B, Campbell B, Shukla M, Awan M, Schultz CJ, Shreenivas A, Wong S, Graboyes E, Pipkorn P, Zenga J
Am J Otolaryngol 2019 Nov-Dec;40(6):102282. Epub 2019 Sep 6 doi: 10.1016/j.amjoto.2019.102282. PMID: 31519432
Ado-trastuzumab emtansine (T-DM1) in patients with HER2-amplified tumors excluding breast and gastric/gastroesophageal junction (GEJ) adenocarcinomas: results from the NCI-MATCH trial (EAY131) subprotocol Q.
Jhaveri KL, Wang XV, Makker V, Luoh SW, Mitchell EP, Zwiebel JA, Sharon E, Gray RJ, Li S, McShane LM, Rubinstein LV, Patton D, Williams PM, Hamilton SR, Conley BA, Arteaga CL, Harris LN, O'Dwyer PJ, Chen AP, Flaherty KT
Ann Oncol 2019 Nov 1;30(11):1821-1830. doi: 10.1093/annonc/mdz291. PMID: 31504139Free PMC Article
Intraparotid schwannoma.
McCarthy WA, Cox BL
Arch Pathol Lab Med 2014 Jul;138(7):982-5. doi: 10.5858/arpa.2013-0014-RS. PMID: 24978928

Recent systematic reviews

Clinicopathological Predictors of Survival for Parotid Mucoepidermoid Carcinoma: A Systematic Review.
Cheng EY, Kim JH, Grose EM, Philteos J, Levin M, de Almeida J, Goldstein D
Otolaryngol Head Neck Surg 2023 Apr;168(4):611-618. Epub 2023 Feb 5 doi: 10.1177/01945998221086845. PMID: 35316125
Elective neck dissection in salivary gland malignancies: Systematic review and meta-analysis.
Yan F, Lao WP, Nguyen SA, Sharma AK, Day TA
Head Neck 2022 Feb;44(2):505-517. Epub 2021 Dec 4 doi: 10.1002/hed.26923. PMID: 34862810
Clinicopathological analysis and survival outcomes of primary salivary gland tumors in pediatric patients: A systematic review.
Louredo BVR, Santos-Silva AR, Vargas PA, Ajudarte Lopes M, Martins MD, Guerra ENDS, Prado Ribeiro AC, Brandão TB, de Mendonça RMH, Kowalski LP, Speight PM, Khurram SA, Pérez-de-Oliveira ME
J Oral Pathol Med 2021 May;50(5):435-443. Epub 2021 Jan 8 doi: 10.1111/jop.13151. PMID: 33314344
Survival and characteristics of pediatric salivary gland cancer: A systematic review and meta-analysis.
Zamani M, Grønhøj C, Schmidt Jensen J, von Buchwald C, Charabi BW, Hjuler T
Pediatr Blood Cancer 2019 Mar;66(3):e27543. Epub 2018 Oct 30 doi: 10.1002/pbc.27543. PMID: 30378272

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