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Cervical Atrophy

MedGen UID:
1789357
•Concept ID:
C0849804
•
Disease or Syndrome
Synonym: Atrophy of the Uterine Cervix

Definition

A condition characterized by the absence of squamous maturation in the cervical epithelium. It is associated with decreased estrogen production. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCervical Atrophy

Professional guidelines

PubMed

Clinical management of vaginal bleeding in postmenopausal women.
Carugno J
Climacteric 2020 Aug;23(4):343-349. Epub 2020 Apr 1 doi: 10.1080/13697137.2020.1739642. PMID: 32233689
Prevention and Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis.
Daugėlaitė G, Užkuraitytė K, Jagelavičienė E, Filipauskas A
Medicina (Kaunas) 2019 Jan 22;55(2) doi: 10.3390/medicina55020025. PMID: 30678228Free PMC Article
Hashimoto thyroiditis: clinical and diagnostic criteria.
Caturegli P, De Remigis A, Rose NR
Autoimmun Rev 2014 Apr-May;13(4-5):391-7. Epub 2014 Jan 13 doi: 10.1016/j.autrev.2014.01.007. PMID: 24434360

Recent clinical studies

Etiology

Lower accuracy of cytological screening for high-grade squamous intraepithelial neoplasia in women over 50 years of age in Japan.
Miki M, Imaeda Y, Takahashi H, Iwata A, Tsukamoto T, Nomura H, Kotani K, Mitani T, Ichikawa R, Fujii T
Int J Clin Oncol 2022 Feb;27(2):427-433. Epub 2021 Dec 6 doi: 10.1007/s10147-021-02065-w. PMID: 34873649Free PMC Article
Clinical Characteristics and Histologic Features of Hysterectomy Specimens From Transmasculine Individuals.
Cao CD, Amero MA, Marcinkowski KA, Rosenblum NG, Chan JSY, Richard SD
Obstet Gynecol 2021 Jul 1;138(1):51-57. doi: 10.1097/AOG.0000000000004421. PMID: 34259463
Imaging spinal cord atrophy in progressive myelopathies: HTLV-I-associated neurological disease (HAM/TSP) and multiple sclerosis (MS).
Azodi S, Nair G, Enose-Akahata Y, Charlip E, Vellucci A, Cortese I, Dwyer J, Billioux BJ, Thomas C, Ohayon J, Reich DS, Jacobson S
Ann Neurol 2017 Nov;82(5):719-728. Epub 2017 Nov 8 doi: 10.1002/ana.25072. PMID: 29024167
HAM/TSP: association between white matter lesions on magnetic resonance imaging, clinical and cerebrospinal fluid findings.
Puccioni-Sohler M, Gasparetto E, Cabral-Castro MJ, Slatter C, Vidal CM, Cortes RD, Rosen BR, Mainero C
Arq Neuropsiquiatr 2012 Apr;70(4):246-51. doi: 10.1590/s0004-282x2012000400004. PMID: 22510735
Proliferation in "atypical" atrophic pap smears.
Bulten J, de Wilde PC, Boonstra H, Gemmink JH, Hanselaar AG
Gynecol Oncol 2000 Nov;79(2):225-9. doi: 10.1006/gyno.2000.5943. PMID: 11063649

Diagnosis

Lower accuracy of cytological screening for high-grade squamous intraepithelial neoplasia in women over 50 years of age in Japan.
Miki M, Imaeda Y, Takahashi H, Iwata A, Tsukamoto T, Nomura H, Kotani K, Mitani T, Ichikawa R, Fujii T
Int J Clin Oncol 2022 Feb;27(2):427-433. Epub 2021 Dec 6 doi: 10.1007/s10147-021-02065-w. PMID: 34873649Free PMC Article
Proliferation in "atypical" atrophic pap smears.
Bulten J, de Wilde PC, Boonstra H, Gemmink JH, Hanselaar AG
Gynecol Oncol 2000 Nov;79(2):225-9. doi: 10.1006/gyno.2000.5943. PMID: 11063649
Decreased expression of Ki-67 in atrophic cervical epithelium of post-menopausal women.
Bulten J, de Wilde PC, Schijf C, van der Laak JA, Wienk S, Poddighe PJ, Hanselaar AG
J Pathol 2000 Apr;190(5):545-53. doi: 10.1002/(SICI)1096-9896(200004)190:5<545::AID-PATH549>3.0.CO;2-S. PMID: 10727980
Epidemiology of trichomonas vaginalis. A prospective study in China.
Zhang ZF
Sex Transm Dis 1996 Sep-Oct;23(5):415-24. doi: 10.1097/00007435-199609000-00013. PMID: 8885075

Therapy

Clinical Characteristics and Histologic Features of Hysterectomy Specimens From Transmasculine Individuals.
Cao CD, Amero MA, Marcinkowski KA, Rosenblum NG, Chan JSY, Richard SD
Obstet Gynecol 2021 Jul 1;138(1):51-57. doi: 10.1097/AOG.0000000000004421. PMID: 34259463
The relationship between menopausal women infected with the human immunodeficiency virus and cervical atrophy: A cytologic study.
Davies G, Firnhaber C, Pantanowitz L, Michelow P
Diagn Cytopathol 2019 Apr;47(4):302-306. Epub 2018 Dec 26 doi: 10.1002/dc.24092. PMID: 30588777
Proliferation in "atypical" atrophic pap smears.
Bulten J, de Wilde PC, Boonstra H, Gemmink JH, Hanselaar AG
Gynecol Oncol 2000 Nov;79(2):225-9. doi: 10.1006/gyno.2000.5943. PMID: 11063649
Epidemiology of trichomonas vaginalis. A prospective study in China.
Zhang ZF
Sex Transm Dis 1996 Sep-Oct;23(5):415-24. doi: 10.1097/00007435-199609000-00013. PMID: 8885075

Prognosis

Lower accuracy of cytological screening for high-grade squamous intraepithelial neoplasia in women over 50 years of age in Japan.
Miki M, Imaeda Y, Takahashi H, Iwata A, Tsukamoto T, Nomura H, Kotani K, Mitani T, Ichikawa R, Fujii T
Int J Clin Oncol 2022 Feb;27(2):427-433. Epub 2021 Dec 6 doi: 10.1007/s10147-021-02065-w. PMID: 34873649Free PMC Article
Degeneration of the injured cervical cord is associated with remote changes in corticospinal tract integrity and upper limb impairment.
Freund P, Schneider T, Nagy Z, Hutton C, Weiskopf N, Friston K, Wheeler-Kingshott CA, Thompson AJ
PLoS One 2012;7(12):e51729. Epub 2012 Dec 12 doi: 10.1371/journal.pone.0051729. PMID: 23251612Free PMC Article
Corticomotor representation to a human forearm muscle changes following cervical spinal cord injury.
Freund P, Rothwell J, Craggs M, Thompson AJ, Bestmann S
Eur J Neurosci 2011 Dec;34(11):1839-46. Epub 2011 Nov 14 doi: 10.1111/j.1460-9568.2011.07895.x. PMID: 22082003
Proliferation in "atypical" atrophic pap smears.
Bulten J, de Wilde PC, Boonstra H, Gemmink JH, Hanselaar AG
Gynecol Oncol 2000 Nov;79(2):225-9. doi: 10.1006/gyno.2000.5943. PMID: 11063649
Epidemiology of trichomonas vaginalis. A prospective study in China.
Zhang ZF
Sex Transm Dis 1996 Sep-Oct;23(5):415-24. doi: 10.1097/00007435-199609000-00013. PMID: 8885075

Clinical prediction guides

Lower accuracy of cytological screening for high-grade squamous intraepithelial neoplasia in women over 50 years of age in Japan.
Miki M, Imaeda Y, Takahashi H, Iwata A, Tsukamoto T, Nomura H, Kotani K, Mitani T, Ichikawa R, Fujii T
Int J Clin Oncol 2022 Feb;27(2):427-433. Epub 2021 Dec 6 doi: 10.1007/s10147-021-02065-w. PMID: 34873649Free PMC Article
Imaging spinal cord atrophy in progressive myelopathies: HTLV-I-associated neurological disease (HAM/TSP) and multiple sclerosis (MS).
Azodi S, Nair G, Enose-Akahata Y, Charlip E, Vellucci A, Cortese I, Dwyer J, Billioux BJ, Thomas C, Ohayon J, Reich DS, Jacobson S
Ann Neurol 2017 Nov;82(5):719-728. Epub 2017 Nov 8 doi: 10.1002/ana.25072. PMID: 29024167
Degeneration of the injured cervical cord is associated with remote changes in corticospinal tract integrity and upper limb impairment.
Freund P, Schneider T, Nagy Z, Hutton C, Weiskopf N, Friston K, Wheeler-Kingshott CA, Thompson AJ
PLoS One 2012;7(12):e51729. Epub 2012 Dec 12 doi: 10.1371/journal.pone.0051729. PMID: 23251612Free PMC Article
Corticomotor representation to a human forearm muscle changes following cervical spinal cord injury.
Freund P, Rothwell J, Craggs M, Thompson AJ, Bestmann S
Eur J Neurosci 2011 Dec;34(11):1839-46. Epub 2011 Nov 14 doi: 10.1111/j.1460-9568.2011.07895.x. PMID: 22082003
Epidemiology of trichomonas vaginalis. A prospective study in China.
Zhang ZF
Sex Transm Dis 1996 Sep-Oct;23(5):415-24. doi: 10.1097/00007435-199609000-00013. PMID: 8885075

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