U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Peripheral Pulmonary Nodule

MedGen UID:
1790591
•Concept ID:
C5552721
•
Finding
Synonym: Peripheral Pulmonary Lesion

Definition

A pulmonary nodule located in the outer third of the lung. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeripheral Pulmonary Nodule

Professional guidelines

PubMed

Transareolar uniportal video-assisted thoracoscopic surgery for the treatment of male patients with peripheral pulmonary nodules: a novel technique in thoracic surgery.
Lin J, Yin Y, Zhuo Y, Li X, Lai F
Updates Surg 2021 Aug;73(4):1541-1548. Epub 2021 Jan 4 doi: 10.1007/s13304-020-00945-w. PMID: 33394357
The clinical management of bronchogenic carcinoma-- A progress report.
Baker RR
Johns Hopkins Med J 1975 Nov;137(5):208-15. PMID: 1185914

Recent clinical studies

Etiology

Diagnostic accuracy and adequacy of peripheral pulmonary nodules samples obtained by transthoracic needle aspiration.
Lovrenski A, Gardic N, Tegeltija D, Miljkovic D
Cytopathology 2023 Jan;34(1):35-42. Epub 2022 Sep 15 doi: 10.1111/cyt.13176. PMID: 36062401
Hierarchical clock-scale hand-drawn mapping as a simple method for bronchoscopic navigation in peripheral pulmonary nodule.
Zhong CH, Su ZQ, Luo WZ, Rao WY, Feng JX, Tang CL, Chen Y, Chen XB, Fan MY, Li SY
Respir Res 2022 Sep 14;23(1):245. doi: 10.1186/s12931-022-02160-0. PMID: 36104691Free PMC Article
Accuracy of Pulmonary Nodule Sampling Using Robotic Assisted Bronchoscopy with Shape Sensing, Fluoroscopy, and Radial Endobronchial Ultrasound (The ACCURACY Study).
Thiboutot J, Argento AC, Akulian J, Lee HJ, DeMaio A, Kapp CM, Wahidi MM, Yarmus L
Respiration 2022;101(5):485-493. Epub 2022 Mar 28 doi: 10.1159/000522514. PMID: 35344969
The LungVision navigational platform for peripheral lung nodule biopsy and the added value of cryobiopsy.
Pertzov B, Gershman E, Izhakian S, Heching M, Amor SM, Rosengarten D, Kramer MR
Thorac Cancer 2021 Jul;12(13):2007-2012. Epub 2021 Jun 6 doi: 10.1111/1759-7714.14003. PMID: 34096182Free PMC Article
Feasibility and Safety of the Transbronchial Access Tool for Peripheral Pulmonary Nodule and Mass.
Bowling MR, Brown C, Anciano CJ
Ann Thorac Surg 2017 Aug;104(2):443-449. Epub 2017 May 17 doi: 10.1016/j.athoracsur.2017.02.035. PMID: 28527967

Diagnosis

Diagnostic accuracy and adequacy of peripheral pulmonary nodules samples obtained by transthoracic needle aspiration.
Lovrenski A, Gardic N, Tegeltija D, Miljkovic D
Cytopathology 2023 Jan;34(1):35-42. Epub 2022 Sep 15 doi: 10.1111/cyt.13176. PMID: 36062401
Hierarchical clock-scale hand-drawn mapping as a simple method for bronchoscopic navigation in peripheral pulmonary nodule.
Zhong CH, Su ZQ, Luo WZ, Rao WY, Feng JX, Tang CL, Chen Y, Chen XB, Fan MY, Li SY
Respir Res 2022 Sep 14;23(1):245. doi: 10.1186/s12931-022-02160-0. PMID: 36104691Free PMC Article
Radial-EBUS and virtual bronchoscopy planner for peripheral lung cancer diagnosis: How it became the first-line endoscopic procedure.
Lachkar S, Perrot L, Gervereau D, De Marchi M, Morisse Pradier H, Dantoing E, Piton N, Thiberville L, Guisier F, Salaün M
Thorac Cancer 2022 Oct;13(20):2854-2860. Epub 2022 Aug 29 doi: 10.1111/1759-7714.14629. PMID: 36054681Free PMC Article
The LungVision navigational platform for peripheral lung nodule biopsy and the added value of cryobiopsy.
Pertzov B, Gershman E, Izhakian S, Heching M, Amor SM, Rosengarten D, Kramer MR
Thorac Cancer 2021 Jul;12(13):2007-2012. Epub 2021 Jun 6 doi: 10.1111/1759-7714.14003. PMID: 34096182Free PMC Article
Technologies for targeting the peripheral pulmonary nodule including robotics.
Fielding D, Oki M
Respirology 2020 Sep;25(9):914-923. Epub 2020 Feb 26 doi: 10.1111/resp.13791. PMID: 32103596

Therapy

First-in-human use of a new robotic electromagnetic navigation bronchoscopic platform with integrated Tool-in-Lesion Tomosynthesis (TiLT) technology for peripheral pulmonary lesions: The FRONTIER study.
Saghaie T, Williamson JP, Phillips M, Kafili D, Sundar S, Hogarth DK, Ing A
Respirology 2024 Nov;29(11):969-975. Epub 2024 Jun 24 doi: 10.1111/resp.14778. PMID: 38923084
A Novel Electromagnetic Navigation Bronchoscopy System for the Diagnosis of Peripheral Pulmonary Nodules: A Randomized Clinical Trial.
Zheng X, Cao L, Zhang Y, Xie F, Yang H, Liu J, Qu S, Zhang J, Sun J
Ann Am Thorac Soc 2022 Oct;19(10):1730-1739. doi: 10.1513/AnnalsATS.202109-1071OC. PMID: 35679184
The LungVision navigational platform for peripheral lung nodule biopsy and the added value of cryobiopsy.
Pertzov B, Gershman E, Izhakian S, Heching M, Amor SM, Rosengarten D, Kramer MR
Thorac Cancer 2021 Jul;12(13):2007-2012. Epub 2021 Jun 6 doi: 10.1111/1759-7714.14003. PMID: 34096182Free PMC Article
A novel technique for localization of small pulmonary nodules.
Chen W, Chen L, Yang S, Chen Z, Qian G, Zhang S, Jing J
Chest 2007 May;131(5):1526-31. doi: 10.1378/chest.06-1017. PMID: 17494801
Bronchioalveolar cell carcinoma: radiologic appearance and dilemmas in the assessment of response.
Sabloff BS, Truong MT, Wistuba II, Erasmus JJ
Clin Lung Cancer 2004 Sep;6(2):108-12. doi: 10.3816/CLC.2004.n.024. PMID: 15476596

Prognosis

Accuracy of Pulmonary Nodule Sampling Using Robotic Assisted Bronchoscopy with Shape Sensing, Fluoroscopy, and Radial Endobronchial Ultrasound (The ACCURACY Study).
Thiboutot J, Argento AC, Akulian J, Lee HJ, DeMaio A, Kapp CM, Wahidi MM, Yarmus L
Respiration 2022;101(5):485-493. Epub 2022 Mar 28 doi: 10.1159/000522514. PMID: 35344969
Comparing Pulmonary Nodule Location During Electromagnetic Bronchoscopy With Predicted Location on the Basis of Two Virtual Airway Maps at Different Phases of Respiration.
Furukawa BS, Pastis NJ, Tanner NT, Chen A, Silvestri GA
Chest 2018 Jan;153(1):181-186. Epub 2017 Jun 16 doi: 10.1016/j.chest.2017.06.004. PMID: 28629919Free PMC Article
Alveolar adenoma: an extremely rare innocent coin lesion.
Panagiotou I, Kostikas K, Sampaziotis D, Kotoulas C
Interact Cardiovasc Thorac Surg 2012 Mar;14(3):335-7. Epub 2011 Dec 7 doi: 10.1093/icvts/ivr040. PMID: 22159242Free PMC Article
Bronchioalveolar cell carcinoma: radiologic appearance and dilemmas in the assessment of response.
Sabloff BS, Truong MT, Wistuba II, Erasmus JJ
Clin Lung Cancer 2004 Sep;6(2):108-12. doi: 10.3816/CLC.2004.n.024. PMID: 15476596
CT-guided methylene-blue labelling before thoracoscopic resection of pulmonary nodules.
Vandoni RE, Cuttat JF, Wicky S, Suter M
Eur J Cardiothorac Surg 1998 Sep;14(3):265-70. doi: 10.1016/s1010-7940(98)00160-2. PMID: 9761435

Clinical prediction guides

First-in-human use of a new robotic electromagnetic navigation bronchoscopic platform with integrated Tool-in-Lesion Tomosynthesis (TiLT) technology for peripheral pulmonary lesions: The FRONTIER study.
Saghaie T, Williamson JP, Phillips M, Kafili D, Sundar S, Hogarth DK, Ing A
Respirology 2024 Nov;29(11):969-975. Epub 2024 Jun 24 doi: 10.1111/resp.14778. PMID: 38923084
Accuracy of Pulmonary Nodule Sampling Using Robotic Assisted Bronchoscopy with Shape Sensing, Fluoroscopy, and Radial Endobronchial Ultrasound (The ACCURACY Study).
Thiboutot J, Argento AC, Akulian J, Lee HJ, DeMaio A, Kapp CM, Wahidi MM, Yarmus L
Respiration 2022;101(5):485-493. Epub 2022 Mar 28 doi: 10.1159/000522514. PMID: 35344969
Transareolar uniportal video-assisted thoracoscopic surgery for the treatment of male patients with peripheral pulmonary nodules: a novel technique in thoracic surgery.
Lin J, Yin Y, Zhuo Y, Li X, Lai F
Updates Surg 2021 Aug;73(4):1541-1548. Epub 2021 Jan 4 doi: 10.1007/s13304-020-00945-w. PMID: 33394357
Comparing Pulmonary Nodule Location During Electromagnetic Bronchoscopy With Predicted Location on the Basis of Two Virtual Airway Maps at Different Phases of Respiration.
Furukawa BS, Pastis NJ, Tanner NT, Chen A, Silvestri GA
Chest 2018 Jan;153(1):181-186. Epub 2017 Jun 16 doi: 10.1016/j.chest.2017.06.004. PMID: 28629919Free PMC Article
Diagnostic value of transbronchial lung biopsy under fluoroscopic guidance in solitary pulmonary nodule in an endemic area of tuberculosis.
Lai RS, Lee SS, Ting YM, Wang HC, Lin CC, Lu JY
Respir Med 1996 Mar;90(3):139-43. doi: 10.1016/s0954-6111(96)90155-9. PMID: 8736205

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...