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Genetic Predisposition to Neoplasm

MedGen UID:
1791442
•Concept ID:
C5555001
•
Finding

Definition

The predisposition of an individual to develop a neoplasm based on their heredity. [from NCI]

Professional guidelines

PubMed

SCLC: Epidemiology, Risk Factors, Genetic Susceptibility, Molecular Pathology, Screening, and Early Detection.
Wang Q, Gümüş ZH, Colarossi C, Memeo L, Wang X, Kong CY, Boffetta P
J Thorac Oncol 2023 Jan;18(1):31-46. Epub 2022 Oct 12 doi: 10.1016/j.jtho.2022.10.002. PMID: 36243387Free PMC Article
Expert consensus document: Clinical and molecular diagnosis, screening and management of Beckwith-Wiedemann syndrome: an international consensus statement.
Brioude F, Kalish JM, Mussa A, Foster AC, Bliek J, Ferrero GB, Boonen SE, Cole T, Baker R, Bertoletti M, Cocchi G, Coze C, De Pellegrin M, Hussain K, Ibrahim A, Kilby MD, Krajewska-Walasek M, Kratz CP, Ladusans EJ, Lapunzina P, Le Bouc Y, Maas SM, Macdonald F, Õunap K, Peruzzi L, Rossignol S, Russo S, Shipster C, Skórka A, Tatton-Brown K, Tenorio J, Tortora C, Grønskov K, Netchine I, Hennekam RC, Prawitt D, Tümer Z, Eggermann T, Mackay DJG, Riccio A, Maher ER
Nat Rev Endocrinol 2018 Apr;14(4):229-249. Epub 2018 Jan 29 doi: 10.1038/nrendo.2017.166. PMID: 29377879Free PMC Article
Pathophysiology, clinical presentation, and management of colon cancer.
Cappell MS
Gastroenterol Clin North Am 2008 Mar;37(1):1-24, v. doi: 10.1016/j.gtc.2007.12.002. PMID: 18313537

Recent clinical studies

Etiology

The Clinical Spectrum of PTEN Mutations.
Yehia L, Keel E, Eng C
Annu Rev Med 2020 Jan 27;71:103-116. Epub 2019 Aug 21 doi: 10.1146/annurev-med-052218-125823. PMID: 31433956
Gallbladder cancer: epidemiology and genetic risk associations.
Schmidt MA, Marcano-Bonilla L, Roberts LR
Chin Clin Oncol 2019 Aug;8(4):31. doi: 10.21037/cco.2019.08.13. PMID: 31484487
Epidemiology of Intracranial Gliomas.
Ostrom QT, Gittleman H, Stetson L, Virk S, Barnholtz-Sloan JS
Prog Neurol Surg 2018;30:1-11. Epub 2017 Dec 14 doi: 10.1159/000464374. PMID: 29241168
Personalised cancer medicine.
Jackson SE, Chester JD
Int J Cancer 2015 Jul 15;137(2):262-6. Epub 2014 May 12 doi: 10.1002/ijc.28940. PMID: 24789362
Male breast cancer: risk factors, biology, diagnosis, treatment, and survivorship.
Ruddy KJ, Winer EP
Ann Oncol 2013 Jun;24(6):1434-43. Epub 2013 Feb 20 doi: 10.1093/annonc/mdt025. PMID: 23425944

Diagnosis

The Clinical Spectrum of PTEN Mutations.
Yehia L, Keel E, Eng C
Annu Rev Med 2020 Jan 27;71:103-116. Epub 2019 Aug 21 doi: 10.1146/annurev-med-052218-125823. PMID: 31433956
Gallbladder cancer: epidemiology and genetic risk associations.
Schmidt MA, Marcano-Bonilla L, Roberts LR
Chin Clin Oncol 2019 Aug;8(4):31. doi: 10.21037/cco.2019.08.13. PMID: 31484487
Lung cancer: Biology and treatment options.
Lemjabbar-Alaoui H, Hassan OU, Yang YW, Buchanan P
Biochim Biophys Acta 2015 Dec;1856(2):189-210. Epub 2015 Aug 19 doi: 10.1016/j.bbcan.2015.08.002. PMID: 26297204Free PMC Article
Personalised cancer medicine.
Jackson SE, Chester JD
Int J Cancer 2015 Jul 15;137(2):262-6. Epub 2014 May 12 doi: 10.1002/ijc.28940. PMID: 24789362
Male breast cancer: risk factors, biology, diagnosis, treatment, and survivorship.
Ruddy KJ, Winer EP
Ann Oncol 2013 Jun;24(6):1434-43. Epub 2013 Feb 20 doi: 10.1093/annonc/mdt025. PMID: 23425944

Therapy

Coffee consumption and risk of breast cancer: A Mendelian randomization study.
Ellingjord-Dale M, Papadimitriou N, Katsoulis M, Yee C, Dimou N, Gill D, Aune D, Ong JS, MacGregor S, Elsworth B, Lewis SJ, Martin RM, Riboli E, Tsilidis KK
PLoS One 2021;16(1):e0236904. Epub 2021 Jan 19 doi: 10.1371/journal.pone.0236904. PMID: 33465101Free PMC Article
Environmental risk factors for cancer - review paper.
Lewandowska AM, Rudzki M, Rudzki S, Lewandowski T, Laskowska B
Ann Agric Environ Med 2019 Mar 22;26(1):1-7. Epub 2018 Oct 17 doi: 10.26444/aaem/94299. PMID: 30922021
Epidemiology of Intracranial Gliomas.
Ostrom QT, Gittleman H, Stetson L, Virk S, Barnholtz-Sloan JS
Prog Neurol Surg 2018;30:1-11. Epub 2017 Dec 14 doi: 10.1159/000464374. PMID: 29241168
Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification.
Kamps R, Brandão RD, Bosch BJ, Paulussen AD, Xanthoulea S, Blok MJ, Romano A
Int J Mol Sci 2017 Jan 31;18(2) doi: 10.3390/ijms18020308. PMID: 28146134Free PMC Article
Pharmacogenomic biomarkers.
Kirkwood SC, Hockett RD Jr
Dis Markers 2002;18(2):63-71. doi: 10.1155/2002/341708. PMID: 12364812Free PMC Article

Prognosis

The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection.
Patel SG, Karlitz JJ, Yen T, Lieu CH, Boland CR
Lancet Gastroenterol Hepatol 2022 Mar;7(3):262-274. Epub 2022 Jan 26 doi: 10.1016/S2468-1253(21)00426-X. PMID: 35090605
Epidemiology of Follicular Lymphoma.
Cerhan JR
Hematol Oncol Clin North Am 2020 Aug;34(4):631-646. Epub 2020 May 5 doi: 10.1016/j.hoc.2020.02.001. PMID: 32586570Free PMC Article
The Clinical Spectrum of PTEN Mutations.
Yehia L, Keel E, Eng C
Annu Rev Med 2020 Jan 27;71:103-116. Epub 2019 Aug 21 doi: 10.1146/annurev-med-052218-125823. PMID: 31433956
Cutaneous Squamous Cell Carcinoma.
Waldman A, Schmults C
Hematol Oncol Clin North Am 2019 Feb;33(1):1-12. doi: 10.1016/j.hoc.2018.08.001. PMID: 30497667
Leukemia.
Juliusson G, Hough R
Prog Tumor Res 2016;43:87-100. Epub 2016 Sep 5 doi: 10.1159/000447076. PMID: 27595359

Clinical prediction guides

The emerging roles of NGS in clinical oncology and personalized medicine.
Hussen BM, Abdullah ST, Salihi A, Sabir DK, Sidiq KR, Rasul MF, Hidayat HJ, Ghafouri-Fard S, Taheri M, Jamali E
Pathol Res Pract 2022 Feb;230:153760. Epub 2022 Jan 10 doi: 10.1016/j.prp.2022.153760. PMID: 35033746
Genetic risk, incident gastric cancer, and healthy lifestyle: a meta-analysis of genome-wide association studies and prospective cohort study.
Jin G, Lv J, Yang M, Wang M, Zhu M, Wang T, Yan C, Yu C, Ding Y, Li G, Ren C, Ni J, Zhang R, Guo Y, Bian Z, Zheng Y, Zhang N, Jiang Y, Chen J, Wang Y, Xu D, Zheng H, Yang L, Chen Y, Walters R, Millwood IY, Dai J, Ma H, Chen K, Chen Z, Hu Z, Wei Q, Shen H, Li L
Lancet Oncol 2020 Oct;21(10):1378-1386. doi: 10.1016/S1470-2045(20)30460-5. PMID: 33002439
Heterogeneity and cancer.
Allison KH, Sledge GW
Oncology (Williston Park) 2014 Sep;28(9):772-8. PMID: 25224475
Genetic predisposition to pancreatic cancer.
Ghiorzo P
World J Gastroenterol 2014 Aug 21;20(31):10778-89. doi: 10.3748/wjg.v20.i31.10778. PMID: 25152581Free PMC Article
Next-generation sequencing in the clinic: promises and challenges.
Xuan J, Yu Y, Qing T, Guo L, Shi L
Cancer Lett 2013 Nov 1;340(2):284-95. Epub 2012 Nov 19 doi: 10.1016/j.canlet.2012.11.025. PMID: 23174106Free PMC Article

Recent systematic reviews

Germline Testing in Patients With Breast Cancer: ASCO-Society of Surgical Oncology Guideline.
Bedrosian I, Somerfield MR, Achatz MI, Boughey JC, Curigliano G, Friedman S, Kohlmann WK, Kurian AW, Laronga C, Lynce F, Norquist BS, Plichta JK, Rodriguez P, Shah PD, Tischkowitz M, Wood M, Yadav S, Yao K, Robson ME
J Clin Oncol 2024 Feb 10;42(5):584-604. Epub 2024 Jan 4 doi: 10.1200/JCO.23.02225. PMID: 38175972
Hormone replacement therapy in BRCA mutation carriers and risk of ovarian, endometrial, and breast cancer: a systematic review.
Huber D, Seitz S, Kast K, Emons G, Ortmann O
J Cancer Res Clin Oncol 2021 Jul;147(7):2035-2045. Epub 2021 Apr 22 doi: 10.1007/s00432-021-03629-z. PMID: 33885953Free PMC Article
Risk Factors for Gastric Cancer: A Systematic Review.
Yusefi AR, Bagheri Lankarani K, Bastani P, Radinmanesh M, Kavosi Z
Asian Pac J Cancer Prev 2018 Mar 27;19(3):591-603. doi: 10.22034/APJCP.2018.19.3.591. PMID: 29579788Free PMC Article
Risk Factors for Cutaneous Squamous Cell Carcinoma Recurrence, Metastasis, and Disease-Specific Death: A Systematic Review and Meta-analysis.
Thompson AK, Kelley BF, Prokop LJ, Murad MH, Baum CL
JAMA Dermatol 2016 Apr;152(4):419-28. doi: 10.1001/jamadermatol.2015.4994. PMID: 26762219Free PMC Article
Male breast cancer: risk factors, biology, diagnosis, treatment, and survivorship.
Ruddy KJ, Winer EP
Ann Oncol 2013 Jun;24(6):1434-43. Epub 2013 Feb 20 doi: 10.1093/annonc/mdt025. PMID: 23425944

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