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Round Cell Sarcoma with FUS-NFATC2 Gene Fusion

MedGen UID:
1791495
Concept ID:
C5555054
Neoplastic Process
Synonyms: FUS-NFATC2 Sarcoma; FUS::NFATC2 Sarcoma; Round Cell Sarcoma with FUS::NFATC2 Gene Fusion

Definition

A group of rare round and spindle cell sarcomas characterized by the presence of FUS-NFATC2 gene fusion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRound Cell Sarcoma with FUS-NFATC2 Gene Fusion

Recent clinical studies

Etiology

Tsuda Y, Zhang L, Meyers P, Tap WD, Healey JH, Antonescu CR
Genes Chromosomes Cancer 2020 Sep;59(9):525-534. Epub 2020 May 28 doi: 10.1002/gcc.22857. PMID: 32362012Free PMC Article
Watson S, Perrin V, Guillemot D, Reynaud S, Coindre JM, Karanian M, Guinebretière JM, Freneaux P, Le Loarer F, Bouvet M, Galmiche-Rolland L, Larousserie F, Longchampt E, Ranchere-Vince D, Pierron G, Delattre O, Tirode F
J Pathol 2018 May;245(1):29-40. Epub 2018 Mar 30 doi: 10.1002/path.5053. PMID: 29431183

Diagnosis

Ong SLM, Lam SW, van den Akker BEWM, Kroon HM, Briaire-de Bruijn IH, Cleven AHG, Savci-Heijink DC, Cleton-Jansen AM, Baumhoer D, Szuhai K, Bovée JVMG
Am J Surg Pathol 2021 Dec 1;45(12):1669-1681. doi: 10.1097/PAS.0000000000001748. PMID: 34081036Free PMC Article
Hung YP, Fisch AS, Diaz-Perez JA, Iafrate AJ, Lennerz JK, Nardi V, Bredella MA, Raskin KA, Lozano-Calderon SA, Rosenberg AE, Nielsen GP
Histopathology 2021 May;78(6):849-856. Epub 2021 Mar 16 doi: 10.1111/his.14314. PMID: 33316098
Tsuda Y, Zhang L, Meyers P, Tap WD, Healey JH, Antonescu CR
Genes Chromosomes Cancer 2020 Sep;59(9):525-534. Epub 2020 May 28 doi: 10.1002/gcc.22857. PMID: 32362012Free PMC Article
Perret R, Escuriol J, Velasco V, Mayeur L, Soubeyran I, Delfour C, Aubert S, Polivka M, Karanian M, Meurgey A, Le Guellec S, Weingertner N, Hoeller S, Coindre JM, Larousserie F, Pierron G, Tirode F, Le Loarer F
Mod Pathol 2020 Oct;33(10):1930-1944. Epub 2020 Apr 23 doi: 10.1038/s41379-020-0542-z. PMID: 32327700
Diaz-Perez JA, Nielsen GP, Antonescu C, Taylor MS, Lozano-Calderon SA, Rosenberg AE
Hum Pathol 2019 Aug;90:45-53. Epub 2019 May 9 doi: 10.1016/j.humpath.2019.05.001. PMID: 31078563Free PMC Article

Clinical prediction guides

Perret R, Escuriol J, Velasco V, Mayeur L, Soubeyran I, Delfour C, Aubert S, Polivka M, Karanian M, Meurgey A, Le Guellec S, Weingertner N, Hoeller S, Coindre JM, Larousserie F, Pierron G, Tirode F, Le Loarer F
Mod Pathol 2020 Oct;33(10):1930-1944. Epub 2020 Apr 23 doi: 10.1038/s41379-020-0542-z. PMID: 32327700
Watson S, Perrin V, Guillemot D, Reynaud S, Coindre JM, Karanian M, Guinebretière JM, Freneaux P, Le Loarer F, Bouvet M, Galmiche-Rolland L, Larousserie F, Longchampt E, Ranchere-Vince D, Pierron G, Delattre O, Tirode F
J Pathol 2018 May;245(1):29-40. Epub 2018 Mar 30 doi: 10.1002/path.5053. PMID: 29431183

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