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Central Atypical Cartilaginous Tumor

MedGen UID:
1791509
•Concept ID:
C5555068
•
Neoplastic Process

Definition

A locally aggressive, low-grade chondrosarcoma arising in the medulla of bone in the appendicular skeleton. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral Atypical Cartilaginous Tumor

Professional guidelines

PubMed

Local Treatment with Adjuvant Therapy for Central Atypical Cartilaginous Tumors in the Long Bones: Analysis of Outcome and Complications in One Hundred and Eight Patients with a Minimum Follow-up of Two Years.
Dierselhuis EF, Gerbers JG, Ploegmakers JJ, Stevens M, Suurmeijer AJ, Jutte PC
J Bone Joint Surg Am 2016 Feb 17;98(4):303-13. doi: 10.2106/JBJS.O.00472. PMID: 26888678

Recent clinical studies

Therapy

Local Treatment with Adjuvant Therapy for Central Atypical Cartilaginous Tumors in the Long Bones: Analysis of Outcome and Complications in One Hundred and Eight Patients with a Minimum Follow-up of Two Years.
Dierselhuis EF, Gerbers JG, Ploegmakers JJ, Stevens M, Suurmeijer AJ, Jutte PC
J Bone Joint Surg Am 2016 Feb 17;98(4):303-13. doi: 10.2106/JBJS.O.00472. PMID: 26888678

Prognosis

The incidence and diagnostic relevance of pathological fracture in conventional central chondrosarcoma.
Alqubaisi A, Oliveira I, Singla N, Chavda A, Khoo M, Saifuddin A
Skeletal Radiol 2021 Jun;50(6):1131-1140. Epub 2020 Oct 30 doi: 10.1007/s00256-020-03651-1. PMID: 33123743
An imaging protocol for the management of central cartilage tumours of the proximal fibula.
Davies AM, Patel A, James SL, Azzopardi C, Botchu R
Clin Radiol 2020 Sep;75(9):714.e1-714.e6. Epub 2020 Jul 11 doi: 10.1016/j.crad.2020.03.040. PMID: 32665062
A pragmatic approach to the imaging and follow-up of solitary central cartilage tumours of the proximal humerus and knee.
Patel A, Davies AM, Botchu R, James S
Clin Radiol 2019 Jul;74(7):517-526. Epub 2019 Mar 1 doi: 10.1016/j.crad.2019.01.025. PMID: 30827492
Local Treatment with Adjuvant Therapy for Central Atypical Cartilaginous Tumors in the Long Bones: Analysis of Outcome and Complications in One Hundred and Eight Patients with a Minimum Follow-up of Two Years.
Dierselhuis EF, Gerbers JG, Ploegmakers JJ, Stevens M, Suurmeijer AJ, Jutte PC
J Bone Joint Surg Am 2016 Feb 17;98(4):303-13. doi: 10.2106/JBJS.O.00472. PMID: 26888678
MRI differentiation of low-grade from high-grade appendicular chondrosarcoma.
Douis H, Singh L, Saifuddin A
Eur Radiol 2014 Jan;24(1):232-40. Epub 2013 Sep 10 doi: 10.1007/s00330-013-3003-y. PMID: 24337911

Clinical prediction guides

Assessment of central cartilaginous tumor of the appendicular bone: inter-observer and intermodality agreement and comparison of diagnostic performance of CT and MRI.
Lee S, Yoon MA
Acta Radiol 2022 Mar;63(3):376-386. Epub 2021 Feb 27 doi: 10.1177/0284185121996268. PMID: 33641451
Local Treatment with Adjuvant Therapy for Central Atypical Cartilaginous Tumors in the Long Bones: Analysis of Outcome and Complications in One Hundred and Eight Patients with a Minimum Follow-up of Two Years.
Dierselhuis EF, Gerbers JG, Ploegmakers JJ, Stevens M, Suurmeijer AJ, Jutte PC
J Bone Joint Surg Am 2016 Feb 17;98(4):303-13. doi: 10.2106/JBJS.O.00472. PMID: 26888678
Is there a role for diffusion-weighted MRI (DWI) in the diagnosis of central cartilage tumors?
Douis H, Jeys L, Grimer R, Vaiyapuri S, Davies AM
Skeletal Radiol 2015 Jul;44(7):963-9. Epub 2015 Mar 7 doi: 10.1007/s00256-015-2123-7. PMID: 25744812
MRI of chondromyxoid fibroma.
Kim HS, Jee WH, Ryu KN, Cho KH, Suh JS, Cho JH, Choi YS, Lee SM, Lee JM, Sung MS, Kim JY, Jung ES, Chung YG, Ok IY
Acta Radiol 2011 Oct 1;52(8):875-80. Epub 2011 Aug 11 doi: 10.1258/ar.2011.110180. PMID: 21835889
The role of cytogenetics in the classification of soft tissue tumours.
Dei Tos AP, Dal Cin P
Virchows Arch 1997 Aug;431(2):83-94. doi: 10.1007/s004280050073. PMID: 9293889

Recent systematic reviews

Can MRI differentiate between atypical cartilaginous tumors and high-grade chondrosarcoma? A systematic review.
Deckers C, Steyvers MJ, Hannink G, Schreuder HWB, de Rooy JWJ, Van Der Geest ICM
Acta Orthop 2020 Aug;91(4):471-478. Epub 2020 May 20 doi: 10.1080/17453674.2020.1763717. PMID: 32429792Free PMC Article

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