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Yolk Sac Tumor with Somatic-Type Malignancy

MedGen UID:
1791547
Concept ID:
C5555106
Neoplastic Process

Definition

A yolk sac tumor that is characterized by morphologic transformation to somatic-type malignancy. The somatic-type malignant component most often is sarcomatous or carcinomatous. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVYolk Sac Tumor with Somatic-Type Malignancy

Professional guidelines

PubMed

Saani I, Raj N, Sood R, Ansari S, Mandviwala HA, Sanchez E, Boussios S
Int J Environ Res Public Health 2023 Jun 9;20(12) doi: 10.3390/ijerph20126089. PMID: 37372675Free PMC Article
Rice KR, Magers MJ, Beck SD, Cary KC, Einhorn LH, Ulbright TM, Foster RS
J Urol 2014 Nov;192(5):1403-9. Epub 2014 Jun 18 doi: 10.1016/j.juro.2014.05.118. PMID: 24952240
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467

Recent clinical studies

Etiology

Saani I, Raj N, Sood R, Ansari S, Mandviwala HA, Sanchez E, Boussios S
Int J Environ Res Public Health 2023 Jun 9;20(12) doi: 10.3390/ijerph20126089. PMID: 37372675Free PMC Article
Acosta AM, Al-Obaidy KI, Sholl LM, Dickson BC, Lindeman NI, Hirsch MS, Collins K, Fletcher CD, Idrees MT
Am J Surg Pathol 2022 May 1;46(5):701-712. doi: 10.1097/PAS.0000000000001865. PMID: 35034041
Lee YL, Lai CR, Yen MS
J Ovarian Res 2019 Jan 10;12(1):2. doi: 10.1186/s13048-018-0476-y. PMID: 30630520Free PMC Article
Rice KR, Magers MJ, Beck SD, Cary KC, Einhorn LH, Ulbright TM, Foster RS
J Urol 2014 Nov;192(5):1403-9. Epub 2014 Jun 18 doi: 10.1016/j.juro.2014.05.118. PMID: 24952240
Harms D, Zahn S, Göbel U, Schneider DT
Klin Padiatr 2006 Nov-Dec;218(6):296-302. doi: 10.1055/s-2006-942271. PMID: 17080330

Diagnosis

Saani I, Raj N, Sood R, Ansari S, Mandviwala HA, Sanchez E, Boussios S
Int J Environ Res Public Health 2023 Jun 9;20(12) doi: 10.3390/ijerph20126089. PMID: 37372675Free PMC Article
Guo CC, Czerniak B
Hum Pathol 2023 Mar;133:102-114. Epub 2023 Mar 6 doi: 10.1016/j.humpath.2023.02.008. PMID: 36890027
Guo CC, Czerniak B
Hum Pathol 2022 Sep;127:123-135. Epub 2022 Jul 5 doi: 10.1016/j.humpath.2022.06.024. PMID: 35803413
Collins K, Alkashash AM, Hwang M, Kaimakliotis HZ, Cheng L, Idrees MT
Int J Surg Pathol 2022 Apr;30(2):207-213. Epub 2021 Jul 13 doi: 10.1177/10668969211030688. PMID: 34255554
El-Zaatari ZM, Ro JY
Adv Anat Pathol 2021 Sep 1;28(5):335-350. doi: 10.1097/PAP.0000000000000304. PMID: 34029275

Therapy

Rice KR, Magers MJ, Beck SD, Cary KC, Einhorn LH, Ulbright TM, Foster RS
J Urol 2014 Nov;192(5):1403-9. Epub 2014 Jun 18 doi: 10.1016/j.juro.2014.05.118. PMID: 24952240
Garg A, Nahal A, Turcotte R, Tabah R, Alcindor T
Tumori 2013 Jan-Feb;99(1):e24-7. doi: 10.1177/030089161309900128. PMID: 23549017

Prognosis

Bremmer F, Pongratanakul P, Skowron M, Che Y, Richter A, Küffer S, Reuter-Jessen K, Bohnenberger H, Pauls S, Kresbach C, Schüller U, Stühler K, Ströbel P, Albers P, Nettersheim D
Br J Cancer 2023 Nov;129(10):1580-1589. Epub 2023 Sep 19 doi: 10.1038/s41416-023-02425-5. PMID: 37726478Free PMC Article
Guo CC, Czerniak B
Hum Pathol 2023 Mar;133:102-114. Epub 2023 Mar 6 doi: 10.1016/j.humpath.2023.02.008. PMID: 36890027
Stang A, Trocchi P, Kajüter H, Trabert B, Oosterhuis JW, McGlynn KA
Andrology 2023 Jan;11(1):65-72. Epub 2022 Sep 12 doi: 10.1111/andr.13282. PMID: 36059277
Guo CC, Czerniak B
Hum Pathol 2022 Sep;127:123-135. Epub 2022 Jul 5 doi: 10.1016/j.humpath.2022.06.024. PMID: 35803413
Acosta AM, Al-Obaidy KI, Sholl LM, Dickson BC, Lindeman NI, Hirsch MS, Collins K, Fletcher CD, Idrees MT
Am J Surg Pathol 2022 May 1;46(5):701-712. doi: 10.1097/PAS.0000000000001865. PMID: 35034041

Clinical prediction guides

Lee YL, Lai CR, Yen MS
J Ovarian Res 2019 Jan 10;12(1):2. doi: 10.1186/s13048-018-0476-y. PMID: 30630520Free PMC Article
Rice KR, Magers MJ, Beck SD, Cary KC, Einhorn LH, Ulbright TM, Foster RS
J Urol 2014 Nov;192(5):1403-9. Epub 2014 Jun 18 doi: 10.1016/j.juro.2014.05.118. PMID: 24952240
Magers MJ, Kao CS, Cole CD, Rice KR, Foster RS, Einhorn LH, Ulbright TM
Am J Surg Pathol 2014 Oct;38(10):1396-409. doi: 10.1097/PAS.0000000000000262. PMID: 24921638

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