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High Risk Breast Carcinoma

MedGen UID:
1792118
Concept ID:
C5555677
Neoplastic Process
Synonym: High-Risk Breast Carcinoma

Definition

Breast carcinoma with clinicopathologic, cytogenetic, and molecular findings that define a breast carcinoma as high risk. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHigh Risk Breast Carcinoma

Professional guidelines

PubMed

Downes KJ, Glatt BS, Kanchwala SK, Mick R, Fraker DL, Fox KR, Solin LJ, Bucky LP, Czerniecki BJ
Cancer 2005 Mar 1;103(5):906-13. doi: 10.1002/cncr.20851. PMID: 15651068
Gonzalez-Angulo AM, Cristofanilli M, Strom EA, Buzdar AU, Kau SW, Broglio KR, Smith TL, Hortobagyi GN
Cancer 2004 Oct 15;101(8):1760-6. doi: 10.1002/cncr.20530. PMID: 15386311
Hecht JR, Lembo T, Chap L
Cancer 1997 May 1;79(9):1698-702. doi: 10.1002/(sici)1097-0142(19970501)79:9<1698::aid-cncr9>3.0.co;2-8. PMID: 9128984

Recent clinical studies

Etiology

Dayan D, Lukac S, Rack B, Ebner F, Fink V, Leinert E, Veselinovic K, Schütze S, El Taie Z, Janni W, Friedl TWP
Breast Cancer Res 2023 Dec 14;25(1):153. doi: 10.1186/s13058-023-01750-0. PMID: 38098086Free PMC Article
Varma S, Myerson R, Moros E, Taylor M, Straube W, Zoberi I
Int J Hyperthermia 2012;28(7):583-90. Epub 2012 Sep 4 doi: 10.3109/02656736.2012.705216. PMID: 22946861Free PMC Article
Downes KJ, Glatt BS, Kanchwala SK, Mick R, Fraker DL, Fox KR, Solin LJ, Bucky LP, Czerniecki BJ
Cancer 2005 Mar 1;103(5):906-13. doi: 10.1002/cncr.20851. PMID: 15651068
Gonzalez-Angulo AM, Cristofanilli M, Strom EA, Buzdar AU, Kau SW, Broglio KR, Smith TL, Hortobagyi GN
Cancer 2004 Oct 15;101(8):1760-6. doi: 10.1002/cncr.20530. PMID: 15386311
Pérez-Gracia JL, Colomer R, Esteban E, Barceló R, Benavides M, Puertas J, Arcediano A, Tornamira MV, Valentín V, Muñoz A, Cortés-Funes H, Hornedo J
Cancer 2001 Nov 15;92(10):2508-16. doi: 10.1002/1097-0142(20011115)92:10<2508::aid-cncr1601>3.0.co;2-#. PMID: 11745183

Diagnosis

Tomasevic ZI, Rakocevic Z, Tomasevic ZM, Milovanovic Z, Inic M, Kolarevic D, Lukic V, Kovac Z
J BUON 2012 Apr-Jun;17(2):249-53. PMID: 22740201
Gonzalez-Angulo AM, Cristofanilli M, Strom EA, Buzdar AU, Kau SW, Broglio KR, Smith TL, Hortobagyi GN
Cancer 2004 Oct 15;101(8):1760-6. doi: 10.1002/cncr.20530. PMID: 15386311

Therapy

Dayan D, Lukac S, Rack B, Ebner F, Fink V, Leinert E, Veselinovic K, Schütze S, El Taie Z, Janni W, Friedl TWP
Breast Cancer Res 2023 Dec 14;25(1):153. doi: 10.1186/s13058-023-01750-0. PMID: 38098086Free PMC Article
Varma S, Myerson R, Moros E, Taylor M, Straube W, Zoberi I
Int J Hyperthermia 2012;28(7):583-90. Epub 2012 Sep 4 doi: 10.3109/02656736.2012.705216. PMID: 22946861Free PMC Article
Gonzalez-Angulo AM, Cristofanilli M, Strom EA, Buzdar AU, Kau SW, Broglio KR, Smith TL, Hortobagyi GN
Cancer 2004 Oct 15;101(8):1760-6. doi: 10.1002/cncr.20530. PMID: 15386311
Pérez-Gracia JL, Colomer R, Esteban E, Barceló R, Benavides M, Puertas J, Arcediano A, Tornamira MV, Valentín V, Muñoz A, Cortés-Funes H, Hornedo J
Cancer 2001 Nov 15;92(10):2508-16. doi: 10.1002/1097-0142(20011115)92:10<2508::aid-cncr1601>3.0.co;2-#. PMID: 11745183
Hecht JR, Lembo T, Chap L
Cancer 1997 May 1;79(9):1698-702. doi: 10.1002/(sici)1097-0142(19970501)79:9<1698::aid-cncr9>3.0.co;2-8. PMID: 9128984

Prognosis

Dayan D, Lukac S, Rack B, Ebner F, Fink V, Leinert E, Veselinovic K, Schütze S, El Taie Z, Janni W, Friedl TWP
Breast Cancer Res 2023 Dec 14;25(1):153. doi: 10.1186/s13058-023-01750-0. PMID: 38098086Free PMC Article
Gulbahce HE, Vanderwerf S, Blair C, Sweeney C
Hum Pathol 2014 Jan;45(1):78-84. Epub 2013 Oct 21 doi: 10.1016/j.humpath.2013.08.008. PMID: 24157064
Abdel-Fatah TM, Powe DG, Agboola J, Adamowicz-Brice M, Blamey RW, Lopez-Garcia MA, Green AR, Reis-Filho JS, Ellis IO
J Pathol 2010 Mar;220(4):419-34. doi: 10.1002/path.2663. PMID: 20044801
Gonzalez-Angulo AM, Cristofanilli M, Strom EA, Buzdar AU, Kau SW, Broglio KR, Smith TL, Hortobagyi GN
Cancer 2004 Oct 15;101(8):1760-6. doi: 10.1002/cncr.20530. PMID: 15386311
Solano C, Badia B, Lluch A, Marugan I, Benet I, Arbona C, Prosper F, García-Conde J
Bone Marrow Transplant 2001 Feb;27(3):287-93. doi: 10.1038/sj.bmt.1702782. PMID: 11277176

Clinical prediction guides

Dayan D, Lukac S, Rack B, Ebner F, Fink V, Leinert E, Veselinovic K, Schütze S, El Taie Z, Janni W, Friedl TWP
Breast Cancer Res 2023 Dec 14;25(1):153. doi: 10.1186/s13058-023-01750-0. PMID: 38098086Free PMC Article

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