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Unresectable Plexiform Neurofibroma

MedGen UID:
1792120
Concept ID:
C5555679
Neoplastic Process

Definition

Plexiform neurofibroma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Plexiform Neurofibroma

Professional guidelines

PubMed

Brown R
Curr Oncol Rep 2023 Dec;25(12):1409-1417. Epub 2023 Oct 31 doi: 10.1007/s11912-023-01451-z. PMID: 37906356

Recent clinical studies

Etiology

Brown R
Curr Oncol Rep 2023 Dec;25(12):1409-1417. Epub 2023 Oct 31 doi: 10.1007/s11912-023-01451-z. PMID: 37906356
Wollina U, Schönlebe J
Acta Dermatovenerol Croat 2020 Dec;28(7):245-246. PMID: 33835000
Legius E, Brems H
Childs Nerv Syst 2020 Oct;36(10):2285-2295. Epub 2020 Jun 29 doi: 10.1007/s00381-020-04771-8. PMID: 32601904
Jakacki RI, Dombi E, Steinberg SM, Goldman S, Kieran MW, Ullrich NJ, Pollack IF, Goodwin A, Manley PE, Fangusaro J, Allen R, Widemann BC
Neuro Oncol 2017 Feb 1;19(2):289-297. doi: 10.1093/neuonc/now158. PMID: 27510726Free PMC Article
Cavallaro G, Basile U, Polistena A, Giustini S, Arena R, Scorsi A, Zinnamosca L, Letizia C, Calvieri S, De Toma G
Am Surg 2010 Apr;76(4):389-96. PMID: 20420249

Diagnosis

Brown R
Curr Oncol Rep 2023 Dec;25(12):1409-1417. Epub 2023 Oct 31 doi: 10.1007/s11912-023-01451-z. PMID: 37906356
Wollina U, Schönlebe J
Acta Dermatovenerol Croat 2020 Dec;28(7):245-246. PMID: 33835000
Legius E, Brems H
Childs Nerv Syst 2020 Oct;36(10):2285-2295. Epub 2020 Jun 29 doi: 10.1007/s00381-020-04771-8. PMID: 32601904
Cavallaro G, Basile U, Polistena A, Giustini S, Arena R, Scorsi A, Zinnamosca L, Letizia C, Calvieri S, De Toma G
Am Surg 2010 Apr;76(4):389-96. PMID: 20420249
Spinner RJ, Endo T, Amrami KK, Dozois EJ, Babovic-Vuksanovic D, Sim FH
J Neurosurg 2006 Dec;105(6):873-80. doi: 10.3171/jns.2006.105.6.873. PMID: 17405258

Therapy

Brown R
Curr Oncol Rep 2023 Dec;25(12):1409-1417. Epub 2023 Oct 31 doi: 10.1007/s11912-023-01451-z. PMID: 37906356
Hu X, Li W, Zeng K, Xu Z, Li C, Kang Z, Li S, Huang X, Han P, Lin H, Hui AM, Tan Y, Diao L, Li B, Wang X, Wu Z, Lin X
BMC Med 2023 Jul 3;21(1):230. doi: 10.1186/s12916-023-02927-2. PMID: 37400844Free PMC Article
Wang W, Cui XW, Gu YH, Wei CJ, Li YH, Ren JY, Chung MH, Aimaier RH, Zhang HB, Li QF, Wang ZC
J Invest Dermatol 2022 Mar;142(3 Pt A):613-623.e7. Epub 2021 Sep 15 doi: 10.1016/j.jid.2021.07.164. PMID: 34534577
Jakacki RI, Dombi E, Steinberg SM, Goldman S, Kieran MW, Ullrich NJ, Pollack IF, Goodwin A, Manley PE, Fangusaro J, Allen R, Widemann BC
Neuro Oncol 2017 Feb 1;19(2):289-297. doi: 10.1093/neuonc/now158. PMID: 27510726Free PMC Article
Varin J, Poulain L, Hivelin M, Nusbaum P, Hubas A, Laurendeau I, Lantieri L, Wolkenstein P, Vidaud M, Pasmant E, Chapuis N, Parfait B
Oncotarget 2016 Jun 14;7(24):35753-35767. doi: 10.18632/oncotarget.7099. PMID: 26840085Free PMC Article

Prognosis

Brown R
Curr Oncol Rep 2023 Dec;25(12):1409-1417. Epub 2023 Oct 31 doi: 10.1007/s11912-023-01451-z. PMID: 37906356
Legius E, Brems H
Childs Nerv Syst 2020 Oct;36(10):2285-2295. Epub 2020 Jun 29 doi: 10.1007/s00381-020-04771-8. PMID: 32601904
Jakacki RI, Dombi E, Steinberg SM, Goldman S, Kieran MW, Ullrich NJ, Pollack IF, Goodwin A, Manley PE, Fangusaro J, Allen R, Widemann BC
Neuro Oncol 2017 Feb 1;19(2):289-297. doi: 10.1093/neuonc/now158. PMID: 27510726Free PMC Article
Varin J, Poulain L, Hivelin M, Nusbaum P, Hubas A, Laurendeau I, Lantieri L, Wolkenstein P, Vidaud M, Pasmant E, Chapuis N, Parfait B
Oncotarget 2016 Jun 14;7(24):35753-35767. doi: 10.18632/oncotarget.7099. PMID: 26840085Free PMC Article
Cavallaro G, Basile U, Polistena A, Giustini S, Arena R, Scorsi A, Zinnamosca L, Letizia C, Calvieri S, De Toma G
Am Surg 2010 Apr;76(4):389-96. PMID: 20420249

Clinical prediction guides

Hu X, Li W, Zeng K, Xu Z, Li C, Kang Z, Li S, Huang X, Han P, Lin H, Hui AM, Tan Y, Diao L, Li B, Wang X, Wu Z, Lin X
BMC Med 2023 Jul 3;21(1):230. doi: 10.1186/s12916-023-02927-2. PMID: 37400844Free PMC Article
Wollina U, Schönlebe J
Acta Dermatovenerol Croat 2020 Dec;28(7):245-246. PMID: 33835000
Legius E, Brems H
Childs Nerv Syst 2020 Oct;36(10):2285-2295. Epub 2020 Jun 29 doi: 10.1007/s00381-020-04771-8. PMID: 32601904
Varin J, Poulain L, Hivelin M, Nusbaum P, Hubas A, Laurendeau I, Lantieri L, Wolkenstein P, Vidaud M, Pasmant E, Chapuis N, Parfait B
Oncotarget 2016 Jun 14;7(24):35753-35767. doi: 10.18632/oncotarget.7099. PMID: 26840085Free PMC Article
Cavallaro G, Basile U, Polistena A, Giustini S, Arena R, Scorsi A, Zinnamosca L, Letizia C, Calvieri S, De Toma G
Am Surg 2010 Apr;76(4):389-96. PMID: 20420249

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