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Unresectable Colon Carcinoma

MedGen UID:
1792785
Concept ID:
C5556344
Neoplastic Process

Definition

Colon carcinoma that is not amenable to surgical resection. [from NCI]

Professional guidelines

PubMed

Mirza KL, Wickham CJ, Noren ER, Shin J, Cologne KG, Lee SW
Dis Colon Rectum 2021 Dec 1;64(12):1559-1563. doi: 10.1097/DCR.0000000000002112. PMID: 34596631
Song SW, Cheng JF, Liu N, Zhao TH
World J Surg Oncol 2014 Sep 25;12:299. doi: 10.1186/1477-7819-12-299. PMID: 25256096Free PMC Article
Choti MA, Bulkley GB
Liver Transpl Surg 1999 Jan;5(1):65-80. doi: 10.1002/lt.500050113. PMID: 9873095

Recent clinical studies

Etiology

Wang F, Huang YS, Wu HX, Wang ZX, Jin Y, Yao YC, Chen YX, Zhao Q, Chen S, He MM, Luo HY, Qiu MZ, Wang DS, Wang FH, Xu M, Li YH, Xu RH
Gut 2022 Jul;71(7):1340-1349. Epub 2021 Sep 6 doi: 10.1136/gutjnl-2021-324852. PMID: 34489309Free PMC Article
Mirza KL, Wickham CJ, Noren ER, Shin J, Cologne KG, Lee SW
Dis Colon Rectum 2021 Dec 1;64(12):1559-1563. doi: 10.1097/DCR.0000000000002112. PMID: 34596631
Uhlig J, Lukovic J, Dawson LA, Patel RA, Cavnar MJ, Kim HS
Am Soc Clin Oncol Educ Book 2021 Mar;41:133-146. doi: 10.1200/EDBK_320519. PMID: 34010047
Ripley RT, Gajdos C, Reppert AE, Macdermott T, McCarter MD, Pearlman NW
J Surg Oncol 2013 Feb;107(2):144-7. Epub 2012 Aug 23 doi: 10.1002/jso.23211. PMID: 22927225
Schirmer BD
Surg Clin North Am 1996 Jun;76(3):571-83. doi: 10.1016/s0039-6109(05)70463-1. PMID: 8669016

Diagnosis

Mirza KL, Wickham CJ, Noren ER, Shin J, Cologne KG, Lee SW
Dis Colon Rectum 2021 Dec 1;64(12):1559-1563. doi: 10.1097/DCR.0000000000002112. PMID: 34596631
Tanaka T, Kaneko M, Nozawa H, Emoto S, Murono K, Otani K, Sasaki K, Nishikawa T, Kiyomatsu T, Hata K, Morikawa T, Kawai K, Watanabe T
Neuroendocrinology 2017;105(4):426-434. Epub 2017 Jun 23 doi: 10.1159/000478743. PMID: 28641295
Mavrogenis AF, Mimidis G, Kokkalis ZT, Karampi ES, Karampela I, Papagelopoulos PJ, Armaganidis A
Eur J Orthop Surg Traumatol 2014 Apr;24(3):279-83. Epub 2013 Sep 8 doi: 10.1007/s00590-013-1311-1. PMID: 24013815
Muñoz-Casares FC, Rufián S, Rubio MJ, Lizárraga E, Díaz-Iglesias C, Aranda E, Ciria R, Muntané J, Barrios P, Torres-Melero J, González-Moreno S, González-Bayón L, Camps B, Bretcha P, Farré J, Ortega-Pérez G, Gómez-Portilla A
Clin Transl Oncol 2007 Oct;9(10):652-62. doi: 10.1007/s12094-007-0118-0. PMID: 17974526
Didolkar MS, Elias EG, Whitley NO, Keramati B, Jackson AJ, Hebel RJ, Jordan TE
Surg Gynecol Obstet 1985 May;160(5):429-36. PMID: 3992446

Therapy

Wang F, Huang YS, Wu HX, Wang ZX, Jin Y, Yao YC, Chen YX, Zhao Q, Chen S, He MM, Luo HY, Qiu MZ, Wang DS, Wang FH, Xu M, Li YH, Xu RH
Gut 2022 Jul;71(7):1340-1349. Epub 2021 Sep 6 doi: 10.1136/gutjnl-2021-324852. PMID: 34489309Free PMC Article
Lu S, Casarini I, Kato T, Cobo M, Özgüroğlu M, Hodge R, van der Gronde T, Saggese M, Ramalingam SS
Clin Lung Cancer 2021 Jul;22(4):371-375. Epub 2021 Jan 6 doi: 10.1016/j.cllc.2020.11.004. PMID: 33558193
Kennedy AS, Nutting C, Coldwell D, Gaiser J, Drachenberg C
Int J Radiat Oncol Biol Phys 2004 Dec 1;60(5):1552-63. doi: 10.1016/j.ijrobp.2004.09.004. PMID: 15590187
Choti MA, Bulkley GB
Liver Transpl Surg 1999 Jan;5(1):65-80. doi: 10.1002/lt.500050113. PMID: 9873095
Schirmer BD
Surg Clin North Am 1996 Jun;76(3):571-83. doi: 10.1016/s0039-6109(05)70463-1. PMID: 8669016

Prognosis

Wang F, Huang YS, Wu HX, Wang ZX, Jin Y, Yao YC, Chen YX, Zhao Q, Chen S, He MM, Luo HY, Qiu MZ, Wang DS, Wang FH, Xu M, Li YH, Xu RH
Gut 2022 Jul;71(7):1340-1349. Epub 2021 Sep 6 doi: 10.1136/gutjnl-2021-324852. PMID: 34489309Free PMC Article
Lu S, Casarini I, Kato T, Cobo M, Özgüroğlu M, Hodge R, van der Gronde T, Saggese M, Ramalingam SS
Clin Lung Cancer 2021 Jul;22(4):371-375. Epub 2021 Jan 6 doi: 10.1016/j.cllc.2020.11.004. PMID: 33558193
Mavrogenis AF, Mimidis G, Kokkalis ZT, Karampi ES, Karampela I, Papagelopoulos PJ, Armaganidis A
Eur J Orthop Surg Traumatol 2014 Apr;24(3):279-83. Epub 2013 Sep 8 doi: 10.1007/s00590-013-1311-1. PMID: 24013815
Petros JG, Augustinos P, Lopez MJ
Semin Surg Oncol 1999 Oct-Nov;17(3):206-12. doi: 10.1002/(sici)1098-2388(199910/11)17:3<206::aid-ssu10>3.0.co;2-s. PMID: 10504669
Choti MA, Bulkley GB
Liver Transpl Surg 1999 Jan;5(1):65-80. doi: 10.1002/lt.500050113. PMID: 9873095

Clinical prediction guides

Nishikawa Y, Horimatsu T, Oka S, Yamada T, Mitsui K, Yamamoto H, Takahashi K, Shiomi A, Hotta K, Takeuchi Y, Kuwai T, Ishida F, Kudo SE, Saito S, Ueno M, Sunami E, Yamano T, Itabashi M, Ohtsuka K, Kinugasa Y, Matsumoto T, Sugai T, Uraoka T, Kurahara K, Yamaguchi S, Kato T, Okajima M, Kashida H, Fujita F, Ikematsu H, Ito M, Esaki M, Kawai M, Yao T, Hamada M, Koda K, Fukai Y, Komori K, Saitoh Y, Kanemitsu Y, Takamaru H, Yamada K, Nozawa H, Takayama T, Togashi K, Shinto E, Torisu T, Toyoshima A, Ohmiya N, Kato T, Otsuji E, Nagata S, Hashiguchi Y, Sugihara K, Ajioka Y, Tanaka S
JCO Glob Oncol 2024 Feb;10:e2300392. doi: 10.1200/GO.23.00392. PMID: 38330276Free PMC Article
Yim K, Jang WM, Cho U, Sun S, Chong Y, Seo KJ
Medicina (Kaunas) 2022 Jul 12;58(7) doi: 10.3390/medicina58070926. PMID: 35888645Free PMC Article
Leicher LW, Huisman JF, van Grevenstein WMU, Didden P, Backes Y, Offerhaus GJA, Laclé MM, Moll FCP, Geesing JMJ, Smakman N, Droste JSTS, Verdaasdonk EGG, Ter Borg F, Talsma AK, Erkelens GW, van der Zaag ES, Schrauwen RW, van Wely BJ, Schot I, Vermaas M, van Bergeijk JD, Sietses C, Hazen WL, Wasowicz DK, Ramsoekh D, Tuynman JB, Alderlieste YA, Renger RJ, Oort FA, Bilgen EJS, Vleggaar FP, Vasen HFA, de Vos Tot Nederveen Cappel WH, Moons LMG, van Westreenen HL
Ann Surg 2022 May 1;275(5):933-939. Epub 2022 Feb 17 doi: 10.1097/SLA.0000000000005417. PMID: 35185125
Mirza KL, Wickham CJ, Noren ER, Shin J, Cologne KG, Lee SW
Dis Colon Rectum 2021 Dec 1;64(12):1559-1563. doi: 10.1097/DCR.0000000000002112. PMID: 34596631
Uhlig J, Lukovic J, Dawson LA, Patel RA, Cavnar MJ, Kim HS
Am Soc Clin Oncol Educ Book 2021 Mar;41:133-146. doi: 10.1200/EDBK_320519. PMID: 34010047

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