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Non-Febrile Seizure

MedGen UID:
1792903
•Concept ID:
C5556462
•
Sign or Symptom

Definition

A seizure that is not associated with fever. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNon-Febrile Seizure

Professional guidelines

PubMed

Evaluating first seizures in adults in primary care.
Mantoan L, Kullmann DM
Practitioner 2011 Sep;255(1743):25-8, 2-3. PMID: 22032112

Recent clinical studies

Etiology

Recurrence rate of the first nonfebrile seizure in children with autism spectrum disorder.
Jeradeh Boursoulian L, Adeseye V, Malow BA, Ess K
Epilepsy Behav 2021 Sep;122:108187. Epub 2021 Jul 16 doi: 10.1016/j.yebeh.2021.108187. PMID: 34274745Free PMC Article
Focal seizure associated with human parvovirus B19 infection in a non-encephalopathic child.
Samanta D, Willis E
World J Pediatr 2016 Feb;12(1):118-20. Epub 2015 Dec 18 doi: 10.1007/s12519-015-0060-0. PMID: 26684306
Pediatric first time non-febrile seizure with focal manifestations: is emergent imaging indicated?
Aprahamian N, Harper MB, Prabhu SP, Monuteaux MC, Sadiq Z, Torres A, Kimia AA
Seizure 2014 Oct;23(9):740-5. Epub 2014 Jun 8 doi: 10.1016/j.seizure.2014.06.003. PMID: 24970739
Evaluating first seizures in adults in primary care.
Mantoan L, Kullmann DM
Practitioner 2011 Sep;255(1743):25-8, 2-3. PMID: 22032112
Studies of neuron-specific enolase levels in serum and cerebrospinal fluid of children with neurological diseases.
Ko FJ, Chiang CH, Wu CC, Wu L
Gaoxiong Yi Xue Ke Xue Za Zhi 1990 Mar;6(3):137-43. PMID: 2342156

Diagnosis

Advice following a possible first seizure: what do patients attending for EEG remember?
McGonigle O, Russell C, Langan Y
Seizure 2023 Dec;113:19-22. Epub 2023 Oct 30 doi: 10.1016/j.seizure.2023.10.014. PMID: 37924776
Pediatric first time non-febrile seizure with focal manifestations: is emergent imaging indicated?
Aprahamian N, Harper MB, Prabhu SP, Monuteaux MC, Sadiq Z, Torres A, Kimia AA
Seizure 2014 Oct;23(9):740-5. Epub 2014 Jun 8 doi: 10.1016/j.seizure.2014.06.003. PMID: 24970739
Evaluating first seizures in adults in primary care.
Mantoan L, Kullmann DM
Practitioner 2011 Sep;255(1743):25-8, 2-3. PMID: 22032112
Practice parameters in child neurology: do pediatricians use them?
Bale JF Jr, Caplin DA, Bruse JD, Folland D
J Child Neurol 2009 Dec;24(12):1482-5. Epub 2009 Mar 18 doi: 10.1177/0883073809332766. PMID: 19295180
Non-febrile seizure associated with pericallosal lipoma.
Davutoglu M, Yesil Y, Asan A, Dolu H, Karabiber H
Pediatr Neonatol 2008 Dec;49(6):245-7. doi: 10.1016/S1875-9572(09)60019-X. PMID: 19166123

Prognosis

Recurrence rate of the first nonfebrile seizure in children with autism spectrum disorder.
Jeradeh Boursoulian L, Adeseye V, Malow BA, Ess K
Epilepsy Behav 2021 Sep;122:108187. Epub 2021 Jul 16 doi: 10.1016/j.yebeh.2021.108187. PMID: 34274745Free PMC Article
Falling admissions to hospital with febrile seizures in the UK.
Mccrorie K, Thorburn J, Symonds J, Turner SW
Arch Dis Child 2019 Aug;104(8):750-754. Epub 2019 Mar 29 doi: 10.1136/archdischild-2018-316228. PMID: 30926585
EEG characteristics predict subsequent epilepsy in children with their first unprovoked seizure.
Kanemura H, Sano F, Ohyama T, Mizorogi S, Sugita K, Aihara M
Epilepsy Res 2015 Sep;115:58-62. Epub 2015 May 30 doi: 10.1016/j.eplepsyres.2015.05.011. PMID: 26220377
Pediatric first time non-febrile seizure with focal manifestations: is emergent imaging indicated?
Aprahamian N, Harper MB, Prabhu SP, Monuteaux MC, Sadiq Z, Torres A, Kimia AA
Seizure 2014 Oct;23(9):740-5. Epub 2014 Jun 8 doi: 10.1016/j.seizure.2014.06.003. PMID: 24970739
Studies of neuron-specific enolase levels in serum and cerebrospinal fluid of children with neurological diseases.
Ko FJ, Chiang CH, Wu CC, Wu L
Gaoxiong Yi Xue Ke Xue Za Zhi 1990 Mar;6(3):137-43. PMID: 2342156

Clinical prediction guides

Recurrence rate of the first nonfebrile seizure in children with autism spectrum disorder.
Jeradeh Boursoulian L, Adeseye V, Malow BA, Ess K
Epilepsy Behav 2021 Sep;122:108187. Epub 2021 Jul 16 doi: 10.1016/j.yebeh.2021.108187. PMID: 34274745Free PMC Article
Neuro-imaging evaluation after the first afebrile seizure in children: A retrospective observational study.
Al-Shami R, Khair AM, Elseid M, Ibrahim K, Al-Ahmad A, Elsetouhy A, Kamel H, Al Yafei K, Mohamed K
Seizure 2016 Dec;43:26-31. Epub 2016 Oct 19 doi: 10.1016/j.seizure.2016.10.008. PMID: 27821269
EEG characteristics predict subsequent epilepsy in children with their first unprovoked seizure.
Kanemura H, Sano F, Ohyama T, Mizorogi S, Sugita K, Aihara M
Epilepsy Res 2015 Sep;115:58-62. Epub 2015 May 30 doi: 10.1016/j.eplepsyres.2015.05.011. PMID: 26220377
Pediatric first time non-febrile seizure with focal manifestations: is emergent imaging indicated?
Aprahamian N, Harper MB, Prabhu SP, Monuteaux MC, Sadiq Z, Torres A, Kimia AA
Seizure 2014 Oct;23(9):740-5. Epub 2014 Jun 8 doi: 10.1016/j.seizure.2014.06.003. PMID: 24970739

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