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AIDS related complex

MedGen UID:: 1793
•Concept ID:: C0001857
•: Disease or Syndrome

Synonyms:	AIDS Related Complex; AIDS-Related Complex; ARC; Complex, AIDS-Related; Lymphadenopathy Syndrome; Lymphadenopathy Syndromes; Syndrome, Lymphadenopathy; Syndromes, Lymphadenopathy

Monarch Initiative:	MONDO:0005639

Definition

A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating aids-related complex (ARC) from aids include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in aids; follicular or mixed hyperplasia in arc lymph nodes, leading to lymphocyte degeneration and depletion more typical of aids; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown aids. [from MONDO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAIDS related complex

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease Attributes
    - Infectious disease
      - Blood-Borne Infections
        Human immunodeficiency virus infection
        AIDS related complex

Professional guidelines

PubMed

Carotenoids in cancer, mastalgia, and AIDS: prevention and treatment--an overview.

Santamaria L, Bianchi-Santamaria A, dell'Orti M
J Environ Pathol Toxicol Oncol 1996;15(2-4):89-95. PMID: 9216791

Zidovudine toxicity. Clinical features and management.

Rachlis A, Fanning MM
Drug Saf 1993 Apr;8(4):312-20. doi: 10.2165/00002018-199308040-00005. PMID: 8481217

Thymostimulin treatment in AIDS-related complex.

Palmisano L, Chisesi T, Galli M, Gritti FM, Ielasi G, Lazzarin A, Mezzaroma I, Moroni M, Raise E, Vaglia A
Clin Immunol Immunopathol 1988 Jun;47(3):253-61. doi: 10.1016/s0090-1229(88)80003-5. PMID: 3259480

See all (41)

Recent clinical studies

Etiology

The changing face of HIV/AIDS in treated patients.

Llibre JM, Falco V, Tural C, Negredo E, Pineda JA, Muñoz J, Ortega E, Videla S, Sirera G, Martinez E, Miralles C, Iribarren J, Galindo MJ, Domingo P, d'Arminio-Monforte A, Miro JM, Clotet B
Curr HIV Res 2009 Jul;7(4):365-77. doi: 10.2174/157016209788680633. PMID: 19601771

AIDS and cerebrovascular disease.

Pinto AN
Stroke 1996 Mar;27(3):538-43. doi: 10.1161/01.str.27.3.538. PMID: 8610326

Parotid manifestations of HIV infection.

Zeitlen S, Shaha A
J Surg Oncol 1991 Aug;47(4):230-2. doi: 10.1002/jso.2930470406. PMID: 1861494

Thymostimulin treatment in AIDS-related complex.

Fungal infections in patients with AIDS and AIDS-related complex.

Holmberg K, Meyer RD
Scand J Infect Dis 1986;18(3):179-92. doi: 10.3109/00365548609032326. PMID: 3526530

See all (926)

Diagnosis

Pregnancy and AIDS.

Henrion R
Hum Reprod 1988 Feb;3(2):257-62. doi: 10.1093/oxfordjournals.humrep.a136689. PMID: 3281969

AIDS.

Murphy RL, Phair JP
Compr Ther 1988 Jan;14(1):3-12. PMID: 3277764

AIDS-related lymphadenopathies.

Said JW
Semin Diagn Pathol 1988 Nov;5(4):365-75. PMID: 3064217

AIDS-related Kaposi's sarcoma.

Friedman-Kien AE
Recent Results Cancer Res 1988;112:27-36. PMID: 3060917

Generalized lymphadenopathy.

Libman H
J Gen Intern Med 1987 Jan-Feb;2(1):48-58. doi: 10.1007/BF02596251. PMID: 3543267

See all (617)

Therapy

Metabolism of Zidovudine.

Veal GJ, Back DJ
Gen Pharmacol 1995 Nov;26(7):1469-75. doi: 10.1016/0306-3623(95)00047-x. PMID: 8690233

Zidovudine (Retrovir) update.

Rachlis AR
CMAJ 1990 Dec 1;143(11):1177-85. PMID: 2224694 Free PMC Article

Zidovudine intolerance.

Groopman JE
Rev Infect Dis 1990 Jul-Aug;12 Suppl 5:S500-6. doi: 10.1093/clinids/12.supplement_5.s500. PMID: 2201071

Zidovudine update: 1990.

Morse GD, Lechner JL, Santora JA, Rozek SL
DICP 1990 Jul-Aug;24(7-8):754-60. doi: 10.1177/106002809002400720. PMID: 2197818

Odynophagia/dysphagia in AIDS.

Raufman JP
Gastroenterol Clin North Am 1988 Sep;17(3):599-614. PMID: 3049365

See all (551)

Prognosis

Shu Z, Tian Z, Chen J, Ma J, Abudureyimu A, Qian Q, Zhuo L
Ren Fail 2018 Nov;40(1):68-74. doi: 10.1080/0886022X.2017.1419975. PMID: 29299949 Free PMC Article

AIDS.

Murphy RL, Phair JP
Compr Ther 1988 Jan;14(1):3-12. PMID: 3277764

AIDS-related lymphadenopathies.

Said JW
Semin Diagn Pathol 1988 Nov;5(4):365-75. PMID: 3064217

Clinical manifestations of HIV infections.

Kennedy DH
Scott Med J 1987 Aug;32(4):101-7. doi: 10.1177/003693308703200402. PMID: 3313725

Acquired immune deficiency syndrome: review.

Scully C, Cawson RA, Porter SR
Br Dent J 1986 Jul 19;161(2):53-60. doi: 10.1038/sj.bdj.4805895. PMID: 3524629

See all (454)

Clinical prediction guides

Neurocognition with maraviroc compared with tenofovir in HIV.

Robertson KR, Miyahara S, Lee A, Brown TT, Chan ES, Berzins B, Rusin D, Eron JJ, Taiwo BO; AIDS Clinical Trials Group (ACTG) 5303 team
AIDS 2016 Sep 24;30(15):2315-21. doi: 10.1097/QAD.0000000000001189. PMID: 27333088 Free PMC Article

Pathology of AIDS in children.

Joshi VV
Indian J Pediatr 1994 Sep-Oct;61(5):497-512. doi: 10.1007/BF02751710. PMID: 7744451

Parotid manifestations of HIV infection.

Zeitlen S, Shaha A
J Surg Oncol 1991 Aug;47(4):230-2. doi: 10.1002/jso.2930470406. PMID: 1861494

Pregnancy and AIDS.

Henrion R
Hum Reprod 1988 Feb;3(2):257-62. doi: 10.1093/oxfordjournals.humrep.a136689. PMID: 3281969

AIDS-related lymphadenopathies.

Said JW
Semin Diagn Pathol 1988 Nov;5(4):365-75. PMID: 3064217

See all (530)