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AIDS related complex

MedGen UID:
1793
•Concept ID:
C0001857
•
Disease or Syndrome
Synonyms: AIDS Related Complex; AIDS-Related Complex; ARC; Complex, AIDS-Related; Lymphadenopathy Syndrome; Lymphadenopathy Syndromes; Syndrome, Lymphadenopathy; Syndromes, Lymphadenopathy
 
Monarch Initiative: MONDO:0005639

Definition

A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating aids-related complex (ARC) from aids include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in aids; follicular or mixed hyperplasia in arc lymph nodes, leading to lymphocyte degeneration and depletion more typical of aids; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown aids. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAIDS related complex

Professional guidelines

PubMed

Carotenoids in cancer, mastalgia, and AIDS: prevention and treatment--an overview.
Santamaria L, Bianchi-Santamaria A, dell'Orti M
J Environ Pathol Toxicol Oncol 1996;15(2-4):89-95. PMID: 9216791
Zidovudine toxicity. Clinical features and management.
Rachlis A, Fanning MM
Drug Saf 1993 Apr;8(4):312-20. doi: 10.2165/00002018-199308040-00005. PMID: 8481217
Management of the hematologic complications of human immunodeficiency virus infection.
Groopman JE
Rev Infect Dis 1990 Sep-Oct;12(5):931-7. doi: 10.1093/clinids/12.5.931. PMID: 2237134

Recent clinical studies

Etiology

AIDS and cerebrovascular disease.
Pinto AN
Stroke 1996 Mar;27(3):538-43. doi: 10.1161/01.str.27.3.538. PMID: 8610326
AIDS Clinical Trials Group: phase I/II study of combination 2',3'-dideoxycytidine and zidovudine in patients with acquired immunodeficiency syndrome (AIDS) and advanced AIDS-related complex.
Meng TC, Fischl MA, Richman DD
Am J Med 1990 May 21;88(5B):27S-30S. doi: 10.1016/0002-9343(90)90419-e. PMID: 2159707
Pregnancy and AIDS.
Henrion R
Hum Reprod 1988 Feb;3(2):257-62. doi: 10.1093/oxfordjournals.humrep.a136689. PMID: 3281969
AIDS.
Murphy RL, Phair JP
Compr Ther 1988 Jan;14(1):3-12. PMID: 3277764
Fungal infections in patients with AIDS and AIDS-related complex.
Holmberg K, Meyer RD
Scand J Infect Dis 1986;18(3):179-92. doi: 10.3109/00365548609032326. PMID: 3526530

Diagnosis

India: HIV banks.
Kandela P
Lancet 1991 Aug 17;338(8764):436-7. doi: 10.1016/0140-6736(91)91050-5. PMID: 1678096
Pregnancy and AIDS.
Henrion R
Hum Reprod 1988 Feb;3(2):257-62. doi: 10.1093/oxfordjournals.humrep.a136689. PMID: 3281969
AIDS.
Murphy RL, Phair JP
Compr Ther 1988 Jan;14(1):3-12. PMID: 3277764
AIDS-related Kaposi's sarcoma.
Friedman-Kien AE
Recent Results Cancer Res 1988;112:27-36. PMID: 3060917
Fungal infections in patients with AIDS and AIDS-related complex.
Holmberg K, Meyer RD
Scand J Infect Dis 1986;18(3):179-92. doi: 10.3109/00365548609032326. PMID: 3526530

Therapy

Zidovudine: five years later.
McLeod GX, Hammer SM
Ann Intern Med 1992 Sep 15;117(6):487-501. doi: 10.7326/0003-4819-117-6-487. PMID: 1503352
Zidovudine (Retrovir) update.
Rachlis AR
CMAJ 1990 Dec 1;143(11):1177-85. PMID: 2224694Free PMC Article
Zidovudine intolerance.
Groopman JE
Rev Infect Dis 1990 Jul-Aug;12 Suppl 5:S500-6. doi: 10.1093/clinids/12.supplement_5.s500. PMID: 2201071
Zidovudine update: 1990.
Morse GD, Lechner JL, Santora JA, Rozek SL
DICP 1990 Jul-Aug;24(7-8):754-60. doi: 10.1177/106002809002400720. PMID: 2197818
Odynophagia/dysphagia in AIDS.
Raufman JP
Gastroenterol Clin North Am 1988 Sep;17(3):599-614. PMID: 3049365

Prognosis

HIV/AIDS-related hyponatremia: an old but still serious problem.
Shu Z, Tian Z, Chen J, Ma J, Abudureyimu A, Qian Q, Zhuo L
Ren Fail 2018 Nov;40(1):68-74. doi: 10.1080/0886022X.2017.1419975. PMID: 29299949Free PMC Article
Mycobacterium tuberculosis in the acquired immunodeficiency syndrome.
Kaiser-Smith J, Condoluci DV
J Am Osteopath Assoc 1991 Apr;91(4):377-84. PMID: 1874646
AIDS.
Murphy RL, Phair JP
Compr Ther 1988 Jan;14(1):3-12. PMID: 3277764
AIDS-related lymphadenopathies.
Said JW
Semin Diagn Pathol 1988 Nov;5(4):365-75. PMID: 3064217
Acquired immune deficiency syndrome: review.
Scully C, Cawson RA, Porter SR
Br Dent J 1986 Jul 19;161(2):53-60. doi: 10.1038/sj.bdj.4805895. PMID: 3524629

Clinical prediction guides

Pathology of AIDS in children.
Joshi VV
Indian J Pediatr 1994 Sep-Oct;61(5):497-512. doi: 10.1007/BF02751710. PMID: 7744451
The effects of HIV on hematopoiesis.
Calenda V, Chermann JC
Eur J Haematol 1992 Apr;48(4):181-6. doi: 10.1111/j.1600-0609.1992.tb01582.x. PMID: 1592096
Nutritional support of patients with AIDS.
Hickey MS
Surg Clin North Am 1991 Jun;71(3):645-64. doi: 10.1016/s0039-6109(16)45439-3. PMID: 1904649
Pregnancy and AIDS.
Henrion R
Hum Reprod 1988 Feb;3(2):257-62. doi: 10.1093/oxfordjournals.humrep.a136689. PMID: 3281969
AIDS-related lymphadenopathies.
Said JW
Semin Diagn Pathol 1988 Nov;5(4):365-75. PMID: 3064217

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