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Recurrent Higher Risk Myelodysplastic Syndrome

MedGen UID:
1793832
Concept ID:
C5557391
Neoplastic Process
Synonym: Recurrent Higher-Risk Myelodysplastic Syndrome

Definition

The reemergence of higher-risk myelodysplastic syndrome after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Higher Risk Myelodysplastic Syndrome

Professional guidelines

PubMed

Kewan T, Bewersdorf JP, Gurnari C, Xie Z, Stahl M, Zeidan AM
Best Pract Res Clin Haematol 2023 Dec;36(4):101517. Epub 2023 Oct 17 doi: 10.1016/j.beha.2023.101517. PMID: 38092484
Das TP, North D, Fleming SA, Tan JLC, Ivey A, Cummings NJ, Spencer A, Patil SS, Widjaja JML, Swain MI, Bourke C, O'Brien ME, Kliman DS, Curtis DJ
Transplant Cell Ther 2023 Jul;29(7):454.e1-454.e8. Epub 2023 Mar 24 doi: 10.1016/j.jtct.2023.03.025. PMID: 36966870
Geng S, Xu R, Huang X, Li M, Deng C, Lai P, Wang Y, Wu P, Chen X, Weng J, Du X
Front Immunol 2022;13:950134. Epub 2022 Aug 8 doi: 10.3389/fimmu.2022.950134. PMID: 36003379Free PMC Article

Recent clinical studies

Etiology

Kewan T, Bewersdorf JP, Gurnari C, Xie Z, Stahl M, Zeidan AM
Best Pract Res Clin Haematol 2023 Dec;36(4):101517. Epub 2023 Oct 17 doi: 10.1016/j.beha.2023.101517. PMID: 38092484
Oliva EN, Riva M, Niscola P, Santini V, Breccia M, Giai V, Poloni A, Patriarca A, Crisà E, Capodanno I, Salutari P, Reda G, Cascavilla N, Ferrero D, Guarini A, Tripepi G, Iannì G, Russo E, Castelli A, Fattizzo B, Beltrami G, Bocchia M, Molteni A, Fenaux P, Germing U, Ricco A, Palumbo GA, Impera S, Di Renzo N, Rivellini F, Buccisano F, Stamatoullas-Bastard A, Liberati AM, Candoni A, Delfino IM, Arcadi MT, Cufari P, Rizzo L, Bova I, D'Errigo MG, Zini G, Latagliata R
J Clin Oncol 2023 Oct 1;41(28):4486-4496. Epub 2023 Jun 9 doi: 10.1200/JCO.22.02699. PMID: 37294914Free PMC Article
Gibson CJ, Kim HT, Zhao L, Murdock HM, Hambley B, Ogata A, Madero-Marroquin R, Wang S, Green L, Fleharty M, Dougan T, Cheng CA, Blumenstiel B, Cibulskis C, Tsuji J, Duran M, Gocke CD, Antin JH, Nikiforow S, DeZern AE, Chen YB, Ho VT, Jones RJ, Lennon NJ, Walt DR, Ritz J, Soiffer RJ, Gondek LP, Lindsley RC
J Clin Oncol 2022 Jan 10;40(2):189-201. Epub 2021 Nov 18 doi: 10.1200/JCO.21.02286. PMID: 34793200Free PMC Article
Schwind S, Jentzsch M, Kubasch AS, Metzeler KH, Platzbecker U
Neoplasia 2021 Nov;23(11):1101-1109. Epub 2021 Sep 30 doi: 10.1016/j.neo.2021.09.002. PMID: 34601234Free PMC Article
DiNardo CD, Maiti A, Rausch CR, Pemmaraju N, Naqvi K, Daver NG, Kadia TM, Borthakur G, Ohanian M, Alvarado Y, Issa GC, Montalban-Bravo G, Short NJ, Yilmaz M, Bose P, Jabbour EJ, Takahashi K, Burger JA, Garcia-Manero G, Jain N, Kornblau SM, Thompson PA, Estrov Z, Masarova L, Sasaki K, Verstovsek S, Ferrajoli A, Weirda WG, Wang SA, Konoplev S, Chen Z, Pierce SA, Ning J, Qiao W, Ravandi F, Andreeff M, Welch JS, Kantarjian HM, Konopleva MY
Lancet Haematol 2020 Oct;7(10):e724-e736. Epub 2020 Sep 5 doi: 10.1016/S2352-3026(20)30210-6. PMID: 32896301Free PMC Article

Diagnosis

Kewan T, Bewersdorf JP, Gurnari C, Xie Z, Stahl M, Zeidan AM
Best Pract Res Clin Haematol 2023 Dec;36(4):101517. Epub 2023 Oct 17 doi: 10.1016/j.beha.2023.101517. PMID: 38092484
Schwind S, Jentzsch M, Kubasch AS, Metzeler KH, Platzbecker U
Neoplasia 2021 Nov;23(11):1101-1109. Epub 2021 Sep 30 doi: 10.1016/j.neo.2021.09.002. PMID: 34601234Free PMC Article
DiNardo CD, Maiti A, Rausch CR, Pemmaraju N, Naqvi K, Daver NG, Kadia TM, Borthakur G, Ohanian M, Alvarado Y, Issa GC, Montalban-Bravo G, Short NJ, Yilmaz M, Bose P, Jabbour EJ, Takahashi K, Burger JA, Garcia-Manero G, Jain N, Kornblau SM, Thompson PA, Estrov Z, Masarova L, Sasaki K, Verstovsek S, Ferrajoli A, Weirda WG, Wang SA, Konoplev S, Chen Z, Pierce SA, Ning J, Qiao W, Ravandi F, Andreeff M, Welch JS, Kantarjian HM, Konopleva MY
Lancet Haematol 2020 Oct;7(10):e724-e736. Epub 2020 Sep 5 doi: 10.1016/S2352-3026(20)30210-6. PMID: 32896301Free PMC Article
Nazha A, Bejar R
Curr Hematol Malig Rep 2017 Oct;12(5):461-467. doi: 10.1007/s11899-017-0407-9. PMID: 28844082
Bhatt VR, Steensma DP
J Oncol Pract 2016 Sep;12(9):786-92. doi: 10.1200/JOP.2016.015214. PMID: 27621329

Therapy

Oliva EN, Riva M, Niscola P, Santini V, Breccia M, Giai V, Poloni A, Patriarca A, Crisà E, Capodanno I, Salutari P, Reda G, Cascavilla N, Ferrero D, Guarini A, Tripepi G, Iannì G, Russo E, Castelli A, Fattizzo B, Beltrami G, Bocchia M, Molteni A, Fenaux P, Germing U, Ricco A, Palumbo GA, Impera S, Di Renzo N, Rivellini F, Buccisano F, Stamatoullas-Bastard A, Liberati AM, Candoni A, Delfino IM, Arcadi MT, Cufari P, Rizzo L, Bova I, D'Errigo MG, Zini G, Latagliata R
J Clin Oncol 2023 Oct 1;41(28):4486-4496. Epub 2023 Jun 9 doi: 10.1200/JCO.22.02699. PMID: 37294914Free PMC Article
Gibson CJ, Kim HT, Zhao L, Murdock HM, Hambley B, Ogata A, Madero-Marroquin R, Wang S, Green L, Fleharty M, Dougan T, Cheng CA, Blumenstiel B, Cibulskis C, Tsuji J, Duran M, Gocke CD, Antin JH, Nikiforow S, DeZern AE, Chen YB, Ho VT, Jones RJ, Lennon NJ, Walt DR, Ritz J, Soiffer RJ, Gondek LP, Lindsley RC
J Clin Oncol 2022 Jan 10;40(2):189-201. Epub 2021 Nov 18 doi: 10.1200/JCO.21.02286. PMID: 34793200Free PMC Article
Cluzeau T, Sebert M, Rahmé R, Cuzzubbo S, Lehmann-Che J, Madelaine I, Peterlin P, Bève B, Attalah H, Chermat F, Miekoutima E, Rauzy OB, Recher C, Stamatoullas A, Willems L, Raffoux E, Berthon C, Quesnel B, Loschi M, Carpentier AF, Sallman DA, Komrokji R, Walter-Petrich A, Chevret S, Ades L, Fenaux P
J Clin Oncol 2021 May 10;39(14):1575-1583. Epub 2021 Feb 18 doi: 10.1200/JCO.20.02342. PMID: 33600210Free PMC Article
Tanaka TN, Ferrari V, Tarke A, Fields H, Ferrari L, Ferrari F, McCarthy CL, Sanchez AP, Vitiello A, Lane TA, Bejar R
Cytotherapy 2021 Mar;23(3):236-241. Epub 2020 Dec 3 doi: 10.1016/j.jcyt.2020.11.003. PMID: 33279399
DiNardo CD, Maiti A, Rausch CR, Pemmaraju N, Naqvi K, Daver NG, Kadia TM, Borthakur G, Ohanian M, Alvarado Y, Issa GC, Montalban-Bravo G, Short NJ, Yilmaz M, Bose P, Jabbour EJ, Takahashi K, Burger JA, Garcia-Manero G, Jain N, Kornblau SM, Thompson PA, Estrov Z, Masarova L, Sasaki K, Verstovsek S, Ferrajoli A, Weirda WG, Wang SA, Konoplev S, Chen Z, Pierce SA, Ning J, Qiao W, Ravandi F, Andreeff M, Welch JS, Kantarjian HM, Konopleva MY
Lancet Haematol 2020 Oct;7(10):e724-e736. Epub 2020 Sep 5 doi: 10.1016/S2352-3026(20)30210-6. PMID: 32896301Free PMC Article

Prognosis

Kewan T, Bewersdorf JP, Gurnari C, Xie Z, Stahl M, Zeidan AM
Best Pract Res Clin Haematol 2023 Dec;36(4):101517. Epub 2023 Oct 17 doi: 10.1016/j.beha.2023.101517. PMID: 38092484
Oliva EN, Riva M, Niscola P, Santini V, Breccia M, Giai V, Poloni A, Patriarca A, Crisà E, Capodanno I, Salutari P, Reda G, Cascavilla N, Ferrero D, Guarini A, Tripepi G, Iannì G, Russo E, Castelli A, Fattizzo B, Beltrami G, Bocchia M, Molteni A, Fenaux P, Germing U, Ricco A, Palumbo GA, Impera S, Di Renzo N, Rivellini F, Buccisano F, Stamatoullas-Bastard A, Liberati AM, Candoni A, Delfino IM, Arcadi MT, Cufari P, Rizzo L, Bova I, D'Errigo MG, Zini G, Latagliata R
J Clin Oncol 2023 Oct 1;41(28):4486-4496. Epub 2023 Jun 9 doi: 10.1200/JCO.22.02699. PMID: 37294914Free PMC Article
Gibson CJ, Kim HT, Zhao L, Murdock HM, Hambley B, Ogata A, Madero-Marroquin R, Wang S, Green L, Fleharty M, Dougan T, Cheng CA, Blumenstiel B, Cibulskis C, Tsuji J, Duran M, Gocke CD, Antin JH, Nikiforow S, DeZern AE, Chen YB, Ho VT, Jones RJ, Lennon NJ, Walt DR, Ritz J, Soiffer RJ, Gondek LP, Lindsley RC
J Clin Oncol 2022 Jan 10;40(2):189-201. Epub 2021 Nov 18 doi: 10.1200/JCO.21.02286. PMID: 34793200Free PMC Article
Schwind S, Jentzsch M, Kubasch AS, Metzeler KH, Platzbecker U
Neoplasia 2021 Nov;23(11):1101-1109. Epub 2021 Sep 30 doi: 10.1016/j.neo.2021.09.002. PMID: 34601234Free PMC Article
Bhatt VR, Steensma DP
J Oncol Pract 2016 Sep;12(9):786-92. doi: 10.1200/JOP.2016.015214. PMID: 27621329

Clinical prediction guides

Kewan T, Bewersdorf JP, Gurnari C, Xie Z, Stahl M, Zeidan AM
Best Pract Res Clin Haematol 2023 Dec;36(4):101517. Epub 2023 Oct 17 doi: 10.1016/j.beha.2023.101517. PMID: 38092484
Oliva EN, Riva M, Niscola P, Santini V, Breccia M, Giai V, Poloni A, Patriarca A, Crisà E, Capodanno I, Salutari P, Reda G, Cascavilla N, Ferrero D, Guarini A, Tripepi G, Iannì G, Russo E, Castelli A, Fattizzo B, Beltrami G, Bocchia M, Molteni A, Fenaux P, Germing U, Ricco A, Palumbo GA, Impera S, Di Renzo N, Rivellini F, Buccisano F, Stamatoullas-Bastard A, Liberati AM, Candoni A, Delfino IM, Arcadi MT, Cufari P, Rizzo L, Bova I, D'Errigo MG, Zini G, Latagliata R
J Clin Oncol 2023 Oct 1;41(28):4486-4496. Epub 2023 Jun 9 doi: 10.1200/JCO.22.02699. PMID: 37294914Free PMC Article
Lee WH, Lin CC, Tsai CH, Tseng MH, Kuo YY, Liu MC, Tang JL, Sun HI, Chuang YK, Chou WC, Hou HA, Tien HF
Am J Hematol 2022 Dec;97(12):1589-1598. Epub 2022 Oct 10 doi: 10.1002/ajh.26734. PMID: 36109871
Dillon LW, Gui G, Logan BR, Fei M, Ghannam J, Li Y, Licon A, Alyea EP, Bashey A, Devine SM, Fernandez HF, Giralt S, Hamadani M, Howard A, Maziarz RT, Porter DL, Warlick ED, Pasquini MC, Scott BL, Horwitz ME, Deeg HJ, Hourigan CS
JCO Precis Oncol 2021;5 Epub 2021 Jan 25 doi: 10.1200/PO.20.00355. PMID: 34036237Free PMC Article
Cluzeau T, Sebert M, Rahmé R, Cuzzubbo S, Lehmann-Che J, Madelaine I, Peterlin P, Bève B, Attalah H, Chermat F, Miekoutima E, Rauzy OB, Recher C, Stamatoullas A, Willems L, Raffoux E, Berthon C, Quesnel B, Loschi M, Carpentier AF, Sallman DA, Komrokji R, Walter-Petrich A, Chevret S, Ades L, Fenaux P
J Clin Oncol 2021 May 10;39(14):1575-1583. Epub 2021 Feb 18 doi: 10.1200/JCO.20.02342. PMID: 33600210Free PMC Article

Recent systematic reviews

Wang A, Su D, Luo J, Fu Y, Li Q, Chen S
Medicine (Baltimore) 2022 Oct 21;101(42):e31103. doi: 10.1097/MD.0000000000031103. PMID: 36281138Free PMC Article
Ganbat D, Jugder BE, Ganbat L, Tomoeda M, Dungubat E, Takahashi Y, Mori I, Shiomi T, Tomita Y
Curr Cancer Drug Targets 2021;21(6):495-513. doi: 10.2174/1568009621999210120182834. PMID: 33475062
Martí-Carvajal AJ, Anand V, Cardona AF, Solà I
Cochrane Database Syst Rev 2014 Oct 30;(10):CD010340. doi: 10.1002/14651858.CD010340.pub2. PMID: 25356860

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