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Ovarian Sex Cord-Stromal Tumor, Not Otherwise Specified

MedGen UID:
1793867
Concept ID:
C5557426
Neoplastic Process
Synonym: Ovarian Sex Cord-Stromal Tumor, NOS

Definition

A sex cord-stromal tumor that arises from the ovary and lacks the morphologic features that belong to the categories of granulosa-stromal tumors, Sertoli-stromal tumors, or steroid cell tumors. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian Sex Cord-Stromal Tumor, Not Otherwise Specified

Professional guidelines

PubMed

Al Harbi R, McNeish IA, El-Bahrawy M
Int J Gynecol Cancer 2021 Feb;31(2):161-168. Epub 2021 Jan 7 doi: 10.1136/ijgc-2020-002018. PMID: 33414107
Debuquoy C, Romeo C, Vanacker H, Ray-Coquard I
Int J Gynecol Cancer 2020 Jun;30(6):879-887. Epub 2020 May 26 doi: 10.1136/ijgc-2020-001235. PMID: 32461259
Peng Y, Lin J, Guan J, Chen L, Zhang X, Li S, Wang H, Liu M, Guo Y
Abdom Radiol (NY) 2018 Aug;43(8):2156-2168. doi: 10.1007/s00261-017-1419-6. PMID: 29198011

Recent clinical studies

Etiology

Hammer PM, Wang A, Beard C, Zdravkovic S, Tenney T, Liang B, Das I, Bremer R, Wang LC, McCluggage WG, Stewart CJR, Howitt BE
Mod Pathol 2023 Nov;36(11):100318. Epub 2023 Aug 25 doi: 10.1016/j.modpat.2023.100318. PMID: 37634867
Lin M, Bao K, Lu L, Xu S, Liang Y, Cheng X, Wang F
BMC Endocr Disord 2022 Nov 1;22(1):265. doi: 10.1186/s12902-022-01170-9. PMID: 36316664Free PMC Article
Jiang MJ, Le Q, Yang BW, Yuan F, Chen H
J Ovarian Res 2021 Apr 17;14(1):53. doi: 10.1186/s13048-021-00805-0. PMID: 33865445Free PMC Article
Fresneau B, Orbach D, Faure-Conter C, Verité C, Castex MP, Kalfa N, Martelli H, Patte C
Pediatr Blood Cancer 2015 Dec;62(12):2114-9. Epub 2015 Jul 23 doi: 10.1002/pbc.25614. PMID: 26206391
Haroon S, Idrees R, Fatima S, Memon A, Kayani N
J Obstet Gynaecol Res 2015 Mar;41(3):424-31. Epub 2014 Oct 27 doi: 10.1111/jog.12537. PMID: 25345475

Diagnosis

Chao A, Huang HJ, Lin CY, Lee CH, Lin CH, Chao AS, Lai CH, Chang TC, Wu KY, Wu RC
Endocr Relat Cancer 2023 Nov 1;30(11) Epub 2023 Oct 4 doi: 10.1530/ERC-23-0179. PMID: 37655726
Lobaton-Ginsberg M, Malanco-Hernández LM, Ferreira-Hermosillo A
J Med Case Rep 2022 Dec 24;16(1):478. doi: 10.1186/s13256-022-03697-w. PMID: 36564842Free PMC Article
Tjitro A, Wong DA, Ajmal A, Buddhdev K, Brady R
J Investig Med High Impact Case Rep 2022 Jan-Dec;10:23247096211056494. doi: 10.1177/23247096211056494. PMID: 35596563Free PMC Article
Jiang MJ, Le Q, Yang BW, Yuan F, Chen H
J Ovarian Res 2021 Apr 17;14(1):53. doi: 10.1186/s13048-021-00805-0. PMID: 33865445Free PMC Article
Mayer R, Dandulakis M, Richards S, Roque DM, Staats PN
Int J Gynecol Pathol 2020 Nov;39(6):567-572. doi: 10.1097/PGP.0000000000000651. PMID: 31789679

Therapy

Mayer R, Dandulakis M, Richards S, Roque DM, Staats PN
Int J Gynecol Pathol 2020 Nov;39(6):567-572. doi: 10.1097/PGP.0000000000000651. PMID: 31789679
Fresneau B, Orbach D, Faure-Conter C, Verité C, Castex MP, Kalfa N, Martelli H, Patte C
Pediatr Blood Cancer 2015 Dec;62(12):2114-9. Epub 2015 Jul 23 doi: 10.1002/pbc.25614. PMID: 26206391
Brown J, Sood AK, Deavers MT, Milojevic L, Gershenson DM
Gynecol Oncol 2009 Apr;113(1):86-90. Epub 2009 Jan 21 doi: 10.1016/j.ygyno.2008.12.007. PMID: 19162310

Prognosis

Lin M, Bao K, Lu L, Xu S, Liang Y, Cheng X, Wang F
BMC Endocr Disord 2022 Nov 1;22(1):265. doi: 10.1186/s12902-022-01170-9. PMID: 36316664Free PMC Article
Jiang MJ, Le Q, Yang BW, Yuan F, Chen H
J Ovarian Res 2021 Apr 17;14(1):53. doi: 10.1186/s13048-021-00805-0. PMID: 33865445Free PMC Article
Vasilevska D, Rudaitis V, Vasilevska D, Mickys U, Wawrysiuk S, Semczuk A
J Int Med Res 2021 Jan;49(1):300060520983195. doi: 10.1177/0300060520983195. PMID: 33435776Free PMC Article
Mayer R, Dandulakis M, Richards S, Roque DM, Staats PN
Int J Gynecol Pathol 2020 Nov;39(6):567-572. doi: 10.1097/PGP.0000000000000651. PMID: 31789679
Fresneau B, Orbach D, Faure-Conter C, Verité C, Castex MP, Kalfa N, Martelli H, Patte C
Pediatr Blood Cancer 2015 Dec;62(12):2114-9. Epub 2015 Jul 23 doi: 10.1002/pbc.25614. PMID: 26206391

Clinical prediction guides

Umeda S, Takase K, Takayama K, Yamamichi T, Higuchi K, Kawai M, Takeuchi M, Inoue M, Usui N
J Pediatr Hematol Oncol 2023 May 1;45(4):e522-e524. Epub 2022 Jun 7 doi: 10.1097/MPH.0000000000002496. PMID: 35700385
Lin M, Bao K, Lu L, Xu S, Liang Y, Cheng X, Wang F
BMC Endocr Disord 2022 Nov 1;22(1):265. doi: 10.1186/s12902-022-01170-9. PMID: 36316664Free PMC Article
Jiang MJ, Le Q, Yang BW, Yuan F, Chen H
J Ovarian Res 2021 Apr 17;14(1):53. doi: 10.1186/s13048-021-00805-0. PMID: 33865445Free PMC Article
Haroon S, Idrees R, Fatima S, Memon A, Kayani N
J Obstet Gynaecol Res 2015 Mar;41(3):424-31. Epub 2014 Oct 27 doi: 10.1111/jog.12537. PMID: 25345475

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